Experimental obstructive jaundice alters claudin-4 expression in intestinal mucosa: effect of bombesin and neurotensin.

abstract：:Proteus syndrome is an extremely rare congenital disorder that produces multifocal overgrowth of tissue. This report presents a surgical case of a large lipoma in the abdominal wall of a patient with Proteus syndrome. She was diagnosed with Proteus syndrome based on certain diagnostic criteria. The neoplasm increased ...

journal_title：World journal of gastroenterology

authors： Nakayama Y,Kusuda S,Nagata N,Yamaguchi K

更新日期：2009-07-14 00:00:00

abstract：AIM:To explore the role and mechanism of total flavone of Abelmoschus manihot (TFA) on epithelial-mesenchymal transition (EMT) progress of Crohn's disease (CD) intestinal fibrosis. METHODS:First, CCK-8 assay was performed to assess TFA on the viability of intestinal epithelial (IEC-6) cells and select the optimal conc...

journal_title：World journal of gastroenterology

authors： Yang BL,Zhu P,Li YR,Xu MM,Wang H,Qiao LC,Xu HX,Chen HJ

更新日期：2018-08-14 00:00:00

abstract：AIM:To elucidate the underlying mechanisms of metastasis and to identify the metabolomic markers of gastric cancer metastasis. METHODS:Gastric tumors from metastatic and non-metastatic groups were used in this study. Metabolites and different metabolic patterns were analyzed by gas chromatography, mass spectrometry an...

journal_title：World journal of gastroenterology

authors： Chen JL,Tang HQ,Hu JD,Fan J,Hong J,Gu JZ

更新日期：2010-12-14 00:00:00

abstract：AIM:To analyze the available evidence about the risk of extrapancreatic malignancies and pancreatic ductal adenocarcinoma associated to pancreatic intraductal papillary mucinous tumors (IPMNs). METHODS:A systematic search of literature was undertaken using MEDLINE, EMBASE, Cochrane and Web-of-Science libraries. No lim...

journal_title：World journal of gastroenterology

authors： Baiocchi GL,Molfino S,Frittoli B,Pigozzi G,Gheza F,Gaverini G,Tarasconi A,Ricci C,Bertagna F,Grazioli L,Tiberio GA,Portolani N

更新日期：2015-06-21 00:00:00

abstract：AIM:To clarify the strategy for early diagnosis of pancreaticobiliary maljunction (PBM) without biliary dilatation and to pathologically examine gallbladder before cancer develops. METHODS:The anatomy of the union of the pancreatic and bile ducts was assessed by using endoscopic retrograde cholangiopancreatography (ER...

journal_title：World journal of gastroenterology

authors： Takuma K,Kamisawa T,Tabata T,Hara S,Kuruma S,Inaba Y,Kurata M,Honda G,Tsuruta K,Horiguchi S,Igarashi Y

更新日期：2012-07-14 00:00:00

abstract：:Microsatellite instability (MSI) is a prognostic factor and a marker of deficient mismatch repair (MMR) in colorectal adenocarcinomas (CRC). However, a proper application of this marker requires understanding the following: (1) The MSI concept: The PCR approach must amplify the correct locus and accurately identify th...

journal_title：World journal of gastroenterology

authors： Blanes A,Diaz-Cano SJ

更新日期：2006-10-07 00:00:00

abstract：:The treatment of alcoholic hepatitis remains one of the most debated topics in medicine and a field of continued research. In this review, we discuss the evolution of scoring systems, including the recent development of the Glasgow alcoholic hepatitis score, role of liver biopsy and current treatment interventions. St...

journal_title：World journal of gastroenterology

authors： Rongey C,Kaplowitz N

更新日期：2006-11-21 00:00:00

abstract：AIM:To evaluate the influence of multiple samplings during esophagogastroduodenoscopy (EGD) on the accuracy of the rapid urease test, and the validity of newly developed rapid urease tests, HelicotecUT plus test and HelicotecUT test, CLO test and ProntoDry test. METHODS:A total of 355 patients undergoing EGD for dyspe...

journal_title：World journal of gastroenterology

authors： Hsu WH,Wang SS,Kuo CH,Chen CY,Chang CW,Hu HM,Wang JY,Yang YC,Lin YC,Wang WM,Wu DC,Wu MT,Kuo FC

更新日期：2010-06-21 00:00:00

abstract：AIM:To assess the value of magnetic resonance elastography (MRE) in detecting advanced fibrosis/cirrhosis in autoimmune hepatitis (AIH). METHODS:In this retrospective study, 36 patients (19 treated and 17 untreated) with histologically confirmed AIH and liver biopsy performed within 3 mo of MRE were identified at a te...

journal_title：World journal of gastroenterology

authors： Wang J,Malik N,Yin M,Smyrk TC,Czaja AJ,Ehman RL,Venkatesh SK

更新日期：2017-02-07 00:00:00

abstract：AIM:To determine the in vivo and in vivo effects of cysteamine (CS) on expression and activity of H(+)-K(+)-ATPase of gastric mucosal cells in weaning piglets. METHODS:Eighteen litters of newborn Xinhuai piglets were employed in the in vivo experiment and allocated to control and treatment groups. From 12 d of age (D1...

journal_title：World journal of gastroenterology

authors： Shi ZM,Du GM,Wei XH,Zhang L,Chen J,Zhao RQ

更新日期：2005-11-14 00:00:00

abstract：:Despite that some approved drugs and genetically engineered vaccines against hepatitis B virus (HBV) are available for HBV patients, HBV infection is still a severe public health problem in the world. All the approved therapeutic drugs (including interferon-alpha and nucleoside analogues) have their limitations. No dr...

journal_title：World journal of gastroenterology

authors： Wu YH

更新日期：2016-01-07 00:00:00

abstract：:Although antagonists of tumor necrosis factor have resulted in major therapeutic benefits in inflammatory bowel disease, the magnitude and durability of response are variable. Similar to previously available drugs such as 5-aminosalicylates and immunomodulators, the therapeutic effect is not universal leaving many peo...

journal_title：World journal of gastroenterology

authors： Krishnareddy S,Swaminath A

更新日期：2014-02-07 00:00:00

abstract：AIM:To define the common deleted region on the long arm of haman chromosome 7q linked to primary gastric carcinomas in Chinese by loss of heterozygosity (LOH) and its clinical significance. METHODS:Nine microsatellite markers distributed over chromosome 7q with an average marker density of 10cM were used to examine 70...

journal_title：World journal of gastroenterology

authors： Weng DS,Li JT,Mai SJ,Pan ZZ,Feng BJ,Feng QS,Huang LX,Wang QJ,Li YQ,Yu XJ,Chen SP,He J,Xia JC

更新日期：2006-04-21 00:00:00

abstract：AIM:To investigate their expression and activity in the rat ileum after exposure to ionizing radiation along with that of the cellular effectors and molecular mediators involved in the regulation of MMPs. METHODS:Rats were exposed to a single 10-Gy dose of X-rays delivered to the abdomen. A combination of methods, suc...

journal_title：World journal of gastroenterology

authors： Strup-Perrot C,Vozenin-Brotons MC,Vandamme M,Linard C,Mathé D

更新日期：2005-10-28 00:00:00

abstract：:Unidimensional transient elastography (TE) is a noninvasive technique, which has been increasingly used in the assessment of diffuse liver diseases. This paper focuses on reviewing the existing data on the use of TE in the diagnosis of fibrosis and in monitoring disease progression in alcoholic liver disease, on the f...

journal_title：World journal of gastroenterology

authors： Lupsor-Platon M,Badea R

更新日期：2015-11-14 00:00:00

abstract：AIM:To study the relationship between anti-beta2-glycoprotein I (abeta2GPI) antibodies and platelet activation state in patients with ulcerative colitis (UC) and its significance. METHODS:Peripheral blood samples were collected from 56 UC patients (34 males and 22 females, aged 43.5 years, range 21-66 years), includin...

journal_title：World journal of gastroenterology

authors： Gao YH,Gao PJ,Wang CG,Wang XC,Piao YF

更新日期：2008-02-07 00:00:00

abstract：AIM:To clarify the previous discrepant conclusions, we performed a meta-analysis to evaluate the prognostic value of red cell distribution width (RDW) in esophageal cancer (EC). METHODS:We searched the PubMed, EMBASE, Web of Science and Cochrane Library databases to identify clinical studies, followed by using STATA v...

journal_title：World journal of gastroenterology

authors： Xu WY,Yang XB,Wang WQ,Bai Y,Long JY,Lin JZ,Xiong JP,Zheng YC,He XD,Zhao HT,Sang XT

更新日期：2018-05-21 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a chronic, progressive, cholestatic liver disease characterized by inflammation and fibrotic obliteration of the hepatic biliary tree. It is commonly associated with inflammatory bowel disease (IBD). A number of complications can occur which require special consideration, the mo...

journal_title：World journal of gastroenterology

authors： Shorbagi A,Bayraktar Y

更新日期：2008-07-07 00:00:00

abstract：AIM:To enhance the clinical utility of electrogastrography (EGG), which has been recorded since 1922, but is clinically unutilized. METHODS:An innovative method to salvage the promise of EGG is proposed by introducing a preliminary procedure, while maintaining the electrodes, standardized equipment, and signal process...

journal_title：World journal of gastroenterology

authors： Poscente MD,Mintchev MP

更新日期：2017-07-07 00:00:00

abstract：AIM:To explore the influence of polymorphisms in genes encoding for the chemokines Stromal cell-Derived Factor-1 (SDF-1)/CXCL12 and Monocyte Chemotactic Protein-1 (MCP-1)/CCL2, or for the chemokine receptor CCR5 on the risks of liver-related death and hepatocellular carcinoma (HCC) occurrence in hepatitis C virus (HCV)...

journal_title：World journal of gastroenterology

authors： Nahon P,Sutton A,Rufat P,Simon C,Trinchet JC,Gattegno L,Beaugrand M,Charnaux N

更新日期：2008-02-07 00:00:00

abstract：AIM:To investigate the role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning (IPC). METHODS:A rat model of acute hepatic ischemia-reperfusion was established, 24 healthy male Wistar rats were randomly divided into sham-operated group, ische...

journal_title：World journal of gastroenterology

authors： Sun K,Liu ZS,Sun Q

更新日期：2004-07-01 00:00:00

abstract：:Endoclip migration into the common bile duct following laparoscopic cholecystectomy (LC) is an extremely rare complication. Migrated endoclip into the common bile duct can cause obstruction, serve as a nidus for stone formation, and cause cholangitis. We report a case of obstructive jaundice and acute biliary pancreat...

journal_title：World journal of gastroenterology

authors： Dolay K,Alis H,Soylu A,Altaca G,Aygun E

更新日期：2007-12-21 00:00:00

abstract：AIM:To analyze the Hepatitis C virus (HCV) genotype distribution and transmission risk factors in a population of unselected patients in Luxembourg. METHODS:Epidemiological information (gender, age and transmission risks) were collected from 802 patients newly diagnosed for hepatitis C and living in Luxembourg, among ...

journal_title：World journal of gastroenterology

authors： Roman F,Hawotte K,Struck D,Ternes AM,Servais JY,Arendt V,Hoffman P,Hemmer R,Staub T,Seguin-Devaux C,Schmit JC

更新日期：2008-02-28 00:00:00

abstract：AIM:To observe the status of tumor-associated B(7) molecule mRNA expression in human colorectal cancer tissue by in situ hybridization. METHODS:The mRNA expression patterns of cancer-associated B(7-1),B(7)H(1),B(7)H(2),ICOS in 22 specimens of human colorectal cancer tissue were monitored by in situ hybridization (ISH)...

journal_title：World journal of gastroenterology

authors： Xiao JX,Bai PS,Lai BC,Li L,Zhu J,Wang YL

更新日期：2005-09-28 00:00:00

abstract：AIM:To establish a visceral pain model via colorectal distension (CRD) and to evaluate the efficiency of behavioral responses of CRD by measuring the score of abdominal withdrawal reflex (AWR) in rats. METHODS:Thirty-eight male SD rats weighing 180-240 g were used to establish the visceral pain model. The rat was inse...

journal_title：World journal of gastroenterology

authors： Yang JP,Yao M,Jiang XH,Wang LN

更新日期：2006-05-07 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is one of the major causes for cancer death worldwide. Treatment of metastatic disease remains challenging as only certain patients benefit from advances made with the intensified chemotherapy regimen folinic acid, irinotecan and oxaliplatin, the epidermal growth factor receptor ...

journal_title：World journal of gastroenterology

authors： Kruger S,Haas M,Ormanns S,Bächmann S,Siveke JT,Kirchner T,Heinemann V,Boeck S

更新日期：2014-08-21 00:00:00

abstract：AIM:To study the effect of IGF-1/IGF-1R and gastrin/CCK-BR on carcinogenesis and development of human gastric carcinoma and to explore its mechanism and provide a credible theoretical foundation for early diagnosis and molecular therapy of gastric carcinoma. METHODS:mRNA expression levels of IGF-1/IGF-1R and gastrin/C...

journal_title：World journal of gastroenterology

authors： Zhao MD,Hu XM,Sun DJ,Zhang Q,Zhang YH,Meng W

更新日期：2005-06-07 00:00:00

abstract：:It is one of the most important problems for general surgeons to decide which operation should be undertaken on patients with intra-abdominal infection, especially those with concomitant abdominal hypertension. Recently, closure techniques using prosthetic meshes in order to retain abdominal tension and to control sep...

journal_title：World journal of gastroenterology

authors： Tekin S,Tekin A,Kucukkartallar T,Cakir M,Kartal A

更新日期：2008-02-07 00:00:00

abstract：AIM:To carry out a hospital-based case-control study to investigate risk factors for intrahepatic cholangiocarcinoma (ICC) in China. METHODS:A total of 312 ICC cases and 438 matched controls were included in the study. The presence of diabetes mellitus, hypertension, hepatolithiasis, primary sclerosing cholangitis, li...

journal_title：World journal of gastroenterology

authors： Zhou YM,Yin ZF,Yang JM,Li B,Shao WY,Xu F,Wang YL,Li DQ

更新日期：2008-01-28 00:00:00

abstract：:Mastocytosis is a clonal neoplastic disorder of the mast cells (MC) that can be limited to the skin (cutaneous mastocytosis) or involve one or more extracutaneous organs (systemic mastocytosis). The clinical manifestations of mastocytosis are heterogeneous ranging from indolent disease with a long-term survival to a h...

journal_title：World journal of gastroenterology

authors： Martins C,Teixeira C,Ribeiro S,Trabulo D,Cardoso C,Mangualde J,Freire R,Gamito É,Alves AL,Cremers I,Alves C,Neves A,Oliveira AP

更新日期：2016-07-28 00:00:00