Ghrelin and gastrointestinal stromal tumors.

abstract：AIM:To investigate the anticancer effect of a recombinant adenovirus-mediated p53 (rAd-p53) combined with 5-fluorouracil (5-FU) in human colon cancer resistant to 5-FU in vivo and the mechanism of rAd-p53 in reversal of 5-FU resistance. METHODS:Nude mice bearing human colon cancer SW480/5-FU (5-FU resistant) were rand...

journal_title：World journal of gastroenterology

authors： Xie Q,Wu MY,Zhang DX,Yang YM,Wang BS,Zhang J,Xu J,Zhong WD,Hu JN

更新日期：2016-08-28 00:00:00

abstract：:AIM:To explore the risk factors of gallbladder stone recurrence.METHODS:A multifactorial analysis was made for 1058 patients in Shanghai area whose gallbladder stones disappeared after different kinds of nonsurgical therapy,including oral litholytic therapy, extracorporeal shock wave lithotripsy and percutaneous chole...

journal_title：World journal of gastroenterology

authors： Chen P,Wang BS,He LQ

更新日期：1999-02-01 00:00:00

abstract：AIM:To translate into Serbian and to investigate the validity of the cross-culturally adapted the chronic liver disease questionnaire (CLDQ). METHODS:The questionnaire was validated in 103 consecutive CLD patients treated between October 2009 and October 2010 at the Clinic for Gastroenterology, Clinical Centre of Serb...

journal_title：World journal of gastroenterology

authors： Popovic DDj,Kovacevic NV,Kisic Tepavcevic DB,Trajkovic GZ,Alempijevic TM,Spuran MM,Krstic MN,Jesic RS,Younossi ZM,Pekmezovic TD

更新日期：2013-08-14 00:00:00

abstract：AIM:To investigate the individual and combined effects of allopurinol and hyperbaric oxygen (HBO) therapy on biochemical and histopathological changes, oxidative stress, and bacterial translocation (BT) in the experimental rat acute pancreatitis (AP). METHODS:Eighty-five Sprague-Dawley rats were included in the study....

journal_title：World journal of gastroenterology

authors： Comert B,Isik AT,Aydin S,Bozoglu E,Unal B,Deveci S,Mas N,Cinar E,Mas MR

更新日期：2007-12-14 00:00:00

abstract：:An appendiceal neurofibroma (ANF) is a rare neoplasm associated with neurofibromatosis type 1(NF-1), an inheritable neurocutaneous disorder that involves multiple systems including the intraabdominal organs. Appendiceal diverticulitis occasionally ruptures in the absence of intense abdominal pain, which can lead to se...

journal_title：World journal of gastroenterology

authors： Ozaki A,Tsukada M,Watanabe K,Tsubokura M,Kato S,Tanimoto T,Kami M,Ohira H,Kanazawa Y

更新日期：2015-09-07 00:00:00

abstract：BACKGROUND:The etiology of inflammatory bowel disease (IBD) is unknown, but it is believed to be multifactorial. The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases. AIM:To test the hygiene hypothesi...

journal_title：World journal of gastroenterology

authors： Salgado VCL,Luiz RR,Boéchat NLF,Leão IS,Schorr BDC,Parente JML,Lima DC,Silveira Júnior ES,Silva GOS,Almeida NP,Vieira A,de Bueno MLQ,Chebli JM,Bertges ÉR,Brugnara LMDC,Junqueira Neto C,Campbell SBG,Discacciati LL,Céza

更新日期：2020-07-07 00:00:00

abstract：:To our knowledge, stercoral perforation of the colon is rarely seen with fewer than 90 cases reported in the literature till date. We explored the principles of management to prevent impending mortality in five patients with this condition. Five patients, two males and three females, whose median age was 64 years, had...

journal_title：World journal of gastroenterology

authors： Huang WS,Wang CS,Hsieh CC,Lin PY,Chin CC,Wang JY

更新日期：2006-01-21 00:00:00

abstract：AIM:To examine the expression of activin A, a member of the transforming growth factor (TGFbeta) superfamily, recently has been reported to be overexpressed in liver cirrhosis, in the course of carbon tetrachloride-induced rat hepatic fibrosis. METHODS:Hepatic fibrosis was induced in rats by subcutaneous injections of...

journal_title：World journal of gastroenterology

authors： Huang X,Li DG,Wang ZR,Wei HS,Cheng JL,Zhan YT,Zhou X,Xu QF,Li X,Lu HM

更新日期：2001-02-01 00:00:00

abstract：AIM:To perform a systematic review and meta-analysis on proton pump inhibitors (PPIs) therapy and the risk of Clostridium difficile infection (CDI). METHODS We conducted a systematic search of MEDLINE/PubMed and seven other databases through January 1990 to March 2017 for published studies that evaluated the associatio...

journal_title：World journal of gastroenterology

authors： Trifan A,Stanciu C,Girleanu I,Stoica OC,Singeap AM,Maxim R,Chiriac SA,Ciobica A,Boiculese L

更新日期：2017-09-21 00:00:00

abstract：AIM:To determine the prognostic significance of isolated tumor cells (ITCs) and lymph node micrometastases in gastric cancer. METHODS:Hematoxylin and eosin-stained slides of lymph node dissections of 632 consecutive gastric cancers were reviewed. Cytokeratin immunostaining was performed in 280 node-negative cases and ...

journal_title：World journal of gastroenterology

authors： Lee HS,Kim MA,Yang HK,Lee BL,Kim WH

更新日期：2005-10-14 00:00:00

abstract：AIM:To observe the therapeutic effects of dexamethasone on rats with severe acute pancreatitis (SAP) and investigate the influences of dexamethasone on the inflammatory mediators and NF-kappaB expression in multiple organs of SAP rats as well as the mechanisms involved. METHODS:Ninety Sprague-Dawley (SD) rats with SAP...

journal_title：World journal of gastroenterology

authors： Zhang XP,Zhang L,Chen LJ,Cheng QH,Wang JM,Cai W,Shen HP,Cai J

更新日期：2007-01-28 00:00:00

abstract：AIM:To clarify the molecular mechanism involved in pathogenesis of colorectal cancer as well as clinical significance of genetic analysis of histological samples. METHODS:A total of 480 blood and tissue specimens were collected in our hospital from January 2011 to October 2012. In the observation group, there were 120...

journal_title：World journal of gastroenterology

authors： Yan ZH,Cui LH,Wang XH,Li C,He X

更新日期：2014-12-28 00:00:00

abstract：:Colorectal adenocarcinoma (CRC) is the third most common type of cancer and the fourth most frequent cause of death due to cancer worldwide. Given the natural history of CRC, early diagnosis appears to be the most appropriate tool to reduce disease-related mortality. A field of recent interest is clinical proteomics, ...

journal_title：World journal of gastroenterology

authors： de Noo ME,Tollenaar RA,Deelder AM,Bouwman LH

更新日期：2006-11-07 00:00:00

abstract：AIM:To evaluate the diagnostic accuracy, sensitivity, specificity of contrast-enhanced computed tomographic colonography in detecting local recurrence of colorectal cancer. METHODS:From January 2000 to December 2004, 434 patients after potentially curative resection for invasive colorectal cancer were followed up for ...

journal_title：World journal of gastroenterology

authors： You YT,Chang Chien CR,Wang JY,Ng KK,Chen JS,Tang R,Chiang JM,Yeh CY,Hsieh PS

更新日期：2006-01-07 00:00:00

abstract：AIM:To evaluate the association between X-ray cross-complementing gene 1 (XRCC1) genetic polymorphism Arg399Gln and gastric cancer risk by means of meta-analysis. METHODS:We searched PubMed and NCBI up to June 1, 2008. A total of 16 clinical trials and reports were identified, but only 8 trials qualified under our sel...

journal_title：World journal of gastroenterology

authors： Geng J,Zhang YW,Huang GC,Chen LB

更新日期：2008-11-21 00:00:00

abstract：AIM:To investigate the hepatoprotective effect of manual acupuncture at Yanglingquan (GB34) on CCl4-induced chronic liver damage in rats. METHODS:Rats were injected intraperitoneally with CCl4 (1 mL/kg) and treated with manual acupuncture using reinforcing manipulation techniques at left GB34 (Yanglingquan) 3 times a ...

journal_title：World journal of gastroenterology

authors： Yim YK,Lee H,Hong KE,Kim YI,Lee BR,Kim TH,Yi JY

更新日期：2006-04-14 00:00:00

abstract：AIM:To evaluate, whether humoral hepatitis-B-vaccine non-responders also fail to mount a T cell response and to compare these results to normal vaccinees. METHODS:Fourty-seven health care employees were enrolled in this study including all available non-responders (n = 13) with an anti-HBsAg titer < 10 kU/L and all av...

journal_title：World journal of gastroenterology

authors： Weihrauch MR,von Bergwelt-Baildon M,Kandic M,Weskott M,Klamp W,Rosler J,Schultze JL

更新日期：2008-04-28 00:00:00

abstract：AIM:To evaluate the effects of omeprazole on gastric mechanosensitivity in humans. METHODS:A double lumen polyvinyl tube with a plastic bag was introduced into the stomach of healthy volunteers under fluorography and connected to a barostat device. Subjects were then positioned so they were sitting comfortably, and th...

journal_title：World journal of gastroenterology

authors： Iida A,Kaneko H,Konagaya T,Funaki Y,Tokudome K,Izawa S,Tamura Y,Mizuno M,Ogasawara N,Sasaki M,Kasugai K

更新日期：2012-10-21 00:00:00

abstract：AIM:To investigate omeprazole-induced transepithelial gastric leak and its effects on the permeability of the peptides bradykinin and oxytocin. METHODS:Rat gastric corpus tissue was isolated and mounted in an Ussing chamber apparatus to evaluate the permeability of (3)H-bradykinin, (3)H-oxytocin, and (14)C-EDTA in the...

journal_title：World journal of gastroenterology

authors： Gabello M,Valenzano MC,Zurbach EP,Mullin JM

更新日期：2010-03-07 00:00:00

abstract：:Aseptic abscesses are an emergent entity and have been described in inflammatory bowel disease, especially in Crohn's disease, and in other diseases. However, aseptic abscesses associated with Behçet's disease are extremely rare. We report a Japanese male diagnosed with an incomplete type of Behçet's disease who devel...

journal_title：World journal of gastroenterology

authors： Maeshima K,Ishii K,Inoue M,Himeno K,Seike M

更新日期：2013-05-28 00:00:00

abstract：BACKGROUND:People with achalasia typically have a thick lower esophageal muscularis propria (LEMP), and peroral endoscopic myotomy (POEM) has been effective in treating most patients. LEMP thickness may be associated with the outcomes and prognosis after POEM. However, more evidence is needed regarding the relationship...

journal_title：World journal of gastroenterology

authors： Liao Y,Xiao TY,Wu YF,Zhang JJ,Zhang BZ,Wang YD,Wang S,Liu X,Sun SY,Guo JT

更新日期：2020-10-14 00:00:00

abstract：AIM:To investigate the existence and clinical significance of hepatitis C virus (HCV) RNA in the serum and peripheral blood mononuclear cells (PBMC) of patients with hepatitis C. METHODS:HCV RNA was detected by nested polymerase chain reaction (Nested PCR) in serum and in PBMC of 46 patients with acute hepatitis C (AH...

journal_title：World journal of gastroenterology

authors： Zhou P,Cai Q,Chen YC,Zhang MS,Guan J,Li XJ

更新日期：1997-06-15 00:00:00

abstract：AIM:To investigate the effects of combined use of emodin and baicalein (CEB) at the cellular and organism levels in severe acute pancreatitis (SAP) and explore the underlying mechanism. METHODS:SAP was induced by retrograde infusion of 5% sodium taurocholate into the pancreatic duct in 48 male SD rats. Pancreatic hist...

journal_title：World journal of gastroenterology

authors： Li J,Zhou R,Bie BB,Huang N,Guo Y,Chen HY,Shi MJ,Yang J,Zhang J,Li ZF

更新日期：2018-01-07 00:00:00

abstract：AIM:To compare the efficacy and safety of single daily amikacin vs. cefotaxime in the 5-d treatment of spontaneous bacterial peritonitis (SBP). METHODS:Thirty-seven cirrhotic patients with SBP, 19 in group A and 18 in group B, were studied. Group A received 1 g of cefotaxime every 6 h, and group B received 500 mg of a...

journal_title：World journal of gastroenterology

authors： Chen TA,Lo GH,Lai KH,Lin WJ

更新日期：2005-11-21 00:00:00

abstract：AIM:To determine if liver stiffness (LS) measurements by means of transient elastography (TE) correlate with the presence of significant esophageal varices (EV) and if they can predict the occurrence of variceal bleeding. METHODS:We studied 1000 cases of liver cirrhosis divided into 2 groups: patients without EV or wi...

journal_title：World journal of gastroenterology

authors： Sporea I,Raţiu I,Sirli R,Popescu A,Bota S

更新日期：2011-05-07 00:00:00

abstract：AIM:To investigate the role of enhancer of zeste homologue 2 (EZH2) and STAT6 immunohistochemistry in the evaluation of clinical stages and prognosis of colorectal cancer (CRC). METHODS:The expression patterns were examined by immunohistochemistry in both tumor and adjacent non-neoplastic tissues of 119 CRC patients w...

journal_title：World journal of gastroenterology

authors： Wang CG,Ye YJ,Yuan J,Liu FF,Zhang H,Wang S

更新日期：2010-05-21 00:00:00

abstract：AIM:To determine the gene expression profile data for the whole liver during development of dimethylni-trosamine (DMN)-induced hepatic fibrosis. METHODS:Marker genes were identified for different types of hepatic cells, including hepatic stellate cells (HSCs), Kupffer cells (including other inflammatory cells), and he...

journal_title：World journal of gastroenterology

authors： Takahara Y,Takahashi M,Wagatsuma H,Yokoya F,Zhang QW,Yamaguchi M,Aburatani H,Kawada N

更新日期：2006-10-28 00:00:00

abstract：BACKGROUND:The introduction of biologics has revolutionized the management of the chronic inflammatory bowel disease, ulcerative colitis (UC), with many patients experiencing significant improvements not only in their symptoms but in other outcomes relevant to individuals and society as a whole. In Germany, there are n...

journal_title：World journal of gastroenterology

authors： Teich N,Grümmer H,Jörgensen E,Liceni T,Holtkamp-Endemann F,Fischer T,Hohenberger S

更新日期：2020-06-07 00:00:00

abstract：AIM:To investigate Helicobacter pylori (H. pylori) eradication rates using second-line bismuth-containing quadruple therapy and to identify predictors of eradication failure. METHODS:This study included 636 patients who failed first-line triple therapy and received 7 d of bismuth-containing quadruple therapy between J...

journal_title：World journal of gastroenterology

authors： Kim SE,Park MI,Park SJ,Moon W,Kim JH,Jung K,Kim HK,Lee YD

更新日期：2017-02-14 00:00:00

abstract：:Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts. In immunocompromised individuals, particularly transplanted patie...

journal_title：World journal of gastroenterology

authors： Umbro I,Tinti F,Muiesan P,Mitterhofer AP

更新日期：2016-01-28 00:00:00