Unusual gastric and pancreatic metastatic renal cell carcinoma presentation 10 years after surgery and immunotherapy: A case report and a review of literature.

abstract：:The scientific framework concerning estrogen effects on different tissues has expanded enormously during the last decades, when estrogen receptor (ER) subtypes were identified. Estrogens are not only essential for the female reproductive system, but they also control fundamental functions in other tissues including th...

journal_title：World journal of gastroenterology

authors： Alvaro D,Mancino MG,Onori P,Franchitto A,Alpini G,Francis H,Glaser S,Gaudio E

更新日期：2006-06-14 00:00:00

abstract：BACKGROUND:Enterotoxigenic Bacteroides fragilis (ETBF) causes colitis and diarrhea, and is considered a candidate pathogen in inflammatory bowel diseases as well as colorectal cancers. These diseases are dependent on ETBF-secreted toxin (BFT). Dendritic cells (DCs) play an important role in directing the nature of adap...

journal_title：World journal of gastroenterology

authors： Ko SH,Jeon JI,Woo HA,Kim JM

更新日期：2020-01-21 00:00:00

abstract：AIM:To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer. METHODS:The new stent is composed of a proximal big cup segment (20 mm in length and 48-55 mm in diameter), a middle part (60 mm in length and 20 mm in dia...

journal_title：World journal of gastroenterology

authors： Shi D,Liao SH,Geng JP

更新日期：2010-09-07 00:00:00

abstract：:The discovery of induced pluripotent stem cells (iPSCs) unraveled a mystery in stem cell research, after identification of four re-programming factors for generating pluripotent stem cells without the need of embryos. This breakthrough in generating iPSCs from somatic cells has overcome the ethical issues and immune r...

journal_title：World journal of gastroenterology

authors： Subba Rao M,Sasikala M,Nageshwar Reddy D

更新日期：2013-06-14 00:00:00

abstract：:Recently, there have been reports from liver biopsies that showed the progression of liver fibrosis in liver transplant patients after the cessation of immunosuppression. Herein, we focused on activated hepatic stellate cells expressing alpha smooth muscle actin (α-SMA) to understand the correlation between immunosupp...

journal_title：World journal of gastroenterology

authors： Hirabaru M,Mochizuki K,Takatsuki M,Soyama A,Kosaka T,Kuroki T,Shimokawa I,Eguchi S

更新日期：2014-06-14 00:00:00

abstract：AIM:Because of a major resistance to chemotherapy, prognosis of hepatocellular carcinoma (HCC) is still poor. New treatments are required and gene therapy may be an option. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in multiple malignant tumors, and using adenoviral vectors has sh...

journal_title：World journal of gastroenterology

authors： Jacob D,Schumacher G,Bahra M,Davis J,Zhu HB,Zhang LD,Teraishi F,Neuhaus P,Fang BL

更新日期：2005-05-07 00:00:00

abstract：:The efficacy of triple therapy for Helicobacter pylori infection has dramatically declined over the last decade, largely related to increasing clarithromycin resistance rates. From a microbiological standpoint, bismuth quadruple therapy is the ideal replacement since it combines drugs for which resistance does not imp...

journal_title：World journal of gastroenterology

authors： Molina-Infante J,Gisbert JP

更新日期：2014-08-14 00:00:00

abstract：AIM:To investigate the role of transforming growth factor (TGF)-β-inducible early gene 1 (TIEG1) in TGF-β-induced growth inhibition in hepatocellular carcinoma (HCC) cells. METHODS:Human hepatocyte and HCC cell lines with varied susceptibilities to TGF-β1 were tested by methylthiazoletetrazolium (MTT) assay. The expre...

journal_title：World journal of gastroenterology

authors： Jiang L,Lai YK,Zhang JF,Chan CY,Lu G,Lin MC,He ML,Li JC,Kung HF

更新日期：2012-05-07 00:00:00

abstract：AIM:To clarify the role of neoadjuvant concurrent chemoradiotherapy (NACCRT) followed by surgical resection for localized or locally advanced perihilar cholangiocarcinoma (CCA). METHODS:We retrospectively reviewed 57 patients who underwent surgical resection with or without NACCRT for perihilar CCA; 12 patients receiv...

journal_title：World journal of gastroenterology

authors： Jung JH,Lee HJ,Lee HS,Jo JH,Cho IR,Chung MJ,Park JY,Park SW,Song SY,Bang S

更新日期：2017-05-14 00:00:00

abstract：:Gut microbiota plays a key role in the pathogenesis of alcoholic liver disease (ALD). Consumption of alcohol leads to increased gut permeability, small intestinal bacterial overgrowth, and enteric dysbiosis. These factors contribute to the increased translocation of microbial products to the liver via the portal tract...

journal_title：World journal of gastroenterology

authors： Sung H,Kim SW,Hong M,Suk KT

更新日期：2016-08-07 00:00:00

abstract：AIM:To improve the technique of tissue microarray (tissue chip). METHODS:A new tissue microarraying method was invented with a common microscope installed with a special holing needle, a sampling needle, and a special box fixing paraffin blocks on the microscope slide carrier. With the movement of microscope tube and ...

journal_title：World journal of gastroenterology

authors： Dan HL,Zhang YL,Zhang Y,Wang YD,Lai ZS,Yang YJ,Cui HH,Jian YT,Geng J,Ding YQ,Guo CH,Zhou DY

更新日期：2004-02-15 00:00:00

abstract：:We have described a previously unreported entity of an intussuscepted neuroendocrine carcinoma of the appendix. Our patient was a 70-year-old man whose only complaint was insipient weight loss. Colonoscopy showed a malignant cecal "polyp", and an extended right hemicolectomy was performed. We have reviewed the literat...

journal_title：World journal of gastroenterology

authors： Thomas RE,Maude K,Rotimi O

更新日期：2006-02-14 00:00:00

abstract：AIM:To search the pathophysiological mechanism of diarrhea based on daily stool weights, fecal electrolytes, osmotic gap and pH. METHODS:Seventy-six patients were included: 51 with microscopic colitis (MC) (40 with lymphocytic colitis (LC); 11 with collagenous colitis (CC)); 7 with MC without diarrhea and 18 as a cont...

journal_title：World journal of gastroenterology

authors： Protic M,Jojic N,Bojic D,Milutinovic S,Necic D,Bojic B,Svorcan P,Krstic M,Popovic O

更新日期：2005-09-21 00:00:00

abstract：AIM:To investigate the effects of butyrate on interleukin (IL)-32alpha expression in epithelial cell lines. METHODS:The human intestinal epithelial cell lines HT-29, SW480, and T84 were used. Intracellular IL-32alpha was determined by Western blotting analyses. IL-32alpha mRNA expression was analyzed by real-time poly...

journal_title：World journal of gastroenterology

authors： Kobori A,Bamba S,Imaeda H,Ban H,Tsujikawa T,Saito Y,Fujiyama Y,Andoh A

更新日期：2010-05-21 00:00:00

abstract：AIM:To evaluate the prophylactic efficacy of hepatitis B immunoglobulin (HBIG) in combination with different nucleos(t)ide analogues. METHODS:A total of 5333 hepatitis B surface antigen-positive patients from the China Liver Transplant Registry database were enrolled between January 2000 and December 2009. Low-dose in...

journal_title：World journal of gastroenterology

authors： Shen S,Jiang L,Xiao GQ,Yan LN,Yang JY,Wen TF,Li B,Wang WT,Xu MQ,Wei YG

更新日期：2015-01-14 00:00:00

abstract：:The Authors summarize problems, criticisms but also advantages and indications regarding the recent surgical proposal of associating liver partition and portal vein ligation (PVL) for staged hepatectomy (ALPPS) for the surgical management of colorectal liver metastases. Looking at published data, the technique, when c...

journal_title：World journal of gastroenterology

authors： Donati M,Stavrou GA,Oldhafer KJ

更新日期：2013-10-21 00:00:00

abstract：:Management of acute diarrhea remains a global challenge, particularly in resource-limiting countries. Oral rehydration solution (ORS), a passive rehydrating therapy developed approximately 40 years ago, remains the mainstay treatment. Although ORS is effective for hydration, since it does not inhibit enterotoxin-media...

journal_title：World journal of gastroenterology

authors： Cheng SX

更新日期：2016-03-07 00:00:00

abstract：:A 66-year-old woman underwent partial splenic embolization (PSE) for hypersplenism with idiopathic portal hypertension (IPH). One week later, contrast-enhanced CT revealed extensive portal vein thrombosis (PVT) and dilated portosystemic shunts. The PVT was not dissolved by the intravenous administration of urokinase. ...

journal_title：World journal of gastroenterology

authors： Nakai M,Sato M,Sahara S,Kawai N,Kimura M,Maeda Y,Ibata Y,Higashi K

更新日期：2006-08-21 00:00:00

abstract：AIM:To examine whether high-flow nasal oxygen (HFNO) availability influences the use of general anesthesia (GA) in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic ultrasound (EUS) and associated outcomes. METHODS:In this retrospective study, patients were stratified into 3 eras...

journal_title：World journal of gastroenterology

authors： Schumann R,Natov NS,Rocuts-Martinez KA,Finkelman MD,Phan TV,Hegde SR,Knapp RM

更新日期：2016-12-21 00:00:00

abstract：:We present a rare case of a 45-year-old woman who presented with epigastric pain associated with early satiety and weight loss. Imaging revealed a large intra-abdominal mass in the epigastrium. Despite intensive investigations, including ultrasound scanning, computed tomography, upper gastrointestinal endoscopy, and p...

journal_title：World journal of gastroenterology

authors： Chin KF,Khair G,Babu PS,Morgan DR

更新日期：2009-08-14 00:00:00

abstract：:Neuroendocrine carcinoma (NEC) of the extrahepatic bile duct is rare, and only 22 cases have been reported. Only two of these were large-cell NEC (LCNEC); the vast majority were small-cell NEC. Here, we report a third case of LCNEC of the extrahepatic bile duct. A 76-year-old male presented to a local hospital with pa...

journal_title：World journal of gastroenterology

authors： Sasatomi E,Nalesnik MA,Marsh JW

更新日期：2013-07-28 00:00:00

abstract：AIM:To compare therapeutic outcomes and adverse events in initial solitary hepatocellular carcinoma (HCC) treated with radiofrequency ablation (RFA) and CyberKnife(®). METHODS:Seventy three consecutive patients with initial solitary HCC treated with RFA (38 patients; RFA group) and CyberKnife(®) (35 patients; CK group...

journal_title：World journal of gastroenterology

authors： Shiozawa K,Watanabe M,Ikehara T,Matsukiyo Y,Kogame M,Kishimoto Y,Okubo Y,Makino H,Tsukamoto N,Igarashi Y,Sumino Y

更新日期：2015-12-28 00:00:00

abstract：BACKGROUND:The formation of liver fibrosis is mainly caused by the activation of hepatic stellate cells (HSCs) and the imbalance of extracellular matrix (ECM) production and degradation. The treatment of liver fibrosis mainly includes removing the cause, inhibiting the activation of HSCs, and inhibiting inflammation. N...

journal_title：World journal of gastroenterology

authors： Zhang YZ,Yao JN,Zhang LF,Wang CF,Zhang XX,Gao B

更新日期：2019-06-28 00:00:00

abstract：AIM:To investigate the changes in apoptosis in gastrointestinal cancer cells from patients with gastrointestinal cancers treated with arsenic trioxide (As₂O₃); and to study the possible molecular mechanisms of such changes by detecting the expression levels of p53 and Bcl-2. METHODS:Twenty patients with gastrointestin...

journal_title：World journal of gastroenterology

authors： Ma ZB,Xu HY,Jiang M,Yang YL,Liu LX,Li YH

更新日期：2014-05-14 00:00:00

abstract：:Abnormal bone metabolism and dysfunction of the calcium-parathyroid hormone-vitamin D axis have been reported in patients with viral hepatitis. Some studies suggested a relationship between vitamin D and viral hepatitis. Genetic studies have provided an opportunity to identify the proteins that link vitamin D to the p...

journal_title：World journal of gastroenterology

authors： Lương Kv,Nguyễn LT

更新日期：2012-10-14 00:00:00

abstract：AIM:To investigate in patients with functional dyspepsia (FD) after an every-day meal whether (1) gastrointestinal (GI) and extra-GI symptoms had any relation with the degree of antral volume, (2) the onset of postprandial symptoms was associated with, and may predict, delayed gastric emptying. METHODS:In 94 symptomat...

journal_title：World journal of gastroenterology

authors： Pallotta N,Pezzotti P,Corazziari E

更新日期：2006-11-21 00:00:00

abstract：BACKGROUND:Unconjugated bilirubin (UCB) is generally considered toxic but has gained recent prominence for its anti-inflammatory properties. However, the effects of it on the interaction between intestinal flora and organisms and how it influences immune responses remain unresolved. AIM:To investigate the role of UCB ...

journal_title：World journal of gastroenterology

authors： Zheng JD,He Y,Yu HY,Liu YL,Ge YX,Li XT,Li X,Wang Y,Guo MR,Qu YL,Qin XF,Jiang MS,Wang XH

更新日期：2019-04-21 00:00:00

abstract：:The goal of therapy in chronic hepatitis C virus (HCV) infection is sustained virological response (SVR) which reflects HCV eradication. Treatment against HCV has dramatically improved with the recent availability of direct-acting antivirals (DAAs) including sofosbuvir, simeprevir, daclatasvir, ledipasvir/sofosbuvir, ...

journal_title：World journal of gastroenterology

authors： Cholongitas E,Pipili C,Papatheodoridis G

更新日期：2015-08-28 00:00:00

abstract：:AIM:To investigate the specific pathogenesis of O-polysaccharide (O-PS) which is on the outer membrane of lipopolysaccharides (LPS) from Shigella flexneri.METHODS:The O-PS was isolated and purified from Shigella flexneri 5 M90T by enzymatic hydrolysis and gel chromatography. Effects of O-PS were observed by in vitro e...

journal_title：World journal of gastroenterology

authors： Zhong QP

更新日期：1999-06-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) results from a complex series of interactions between susceptibility genes, the environment, and the immune system. Recently, some studies provided strong evidence that the process of autophagy affects several aspects of mucosal immune responses. Autophagy is a cellular stress response...

journal_title：World journal of gastroenterology

authors： Iida T,Onodera K,Nakase H

更新日期：2017-03-21 00:00:00