Mechanism of diarrhea in microscopic colitis.

abstract：:According to the main international clinical guidelines, the recommended treatment for locally-advanced rectal cancer is neoadjuvant chemoradiotherapy followed by surgery. However, doubts have been raised about the appropriate definition of clinical complete response (cCR) after neoadjuvant therapy and the role of sur...

journal_title：World journal of gastroenterology

authors： López-Campos F,Martín-Martín M,Fornell-Pérez R,García-Pérez JC,Die-Trill J,Fuentes-Mateos R,López-Durán S,Domínguez-Rullán J,Ferreiro R,Riquelme-Oliveira A,Hervás-Morón A,Couñago F

更新日期：2020-08-07 00:00:00

abstract：:Leiomyomas are the most common benign tumors of the esophagus. They usually occur as a single lesion or as two or three nodules. Only two cases of esophageal multiple leiomyomas comprising more than 10 nodules have been reported previously. Moreover, there have been few reports of esophageal squamous cell carcinoma ov...

journal_title：World journal of gastroenterology

authors： Iwaya T,Maesawa C,Uesugi N,Kimura T,Ikeda K,Kimura Y,Mitomo S,Ishida K,Sato N,Wakabayashi G

更新日期：2006-07-28 00:00:00

abstract：AIM:To clarify whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of chronic pancreatitis (CP). This study aimed at clarifying whether serum chemokine and cytokine levels can become useful biological and functional markers to assess the severity of CP....

journal_title：World journal of gastroenterology

authors： Yasuda M,Ito T,Oono T,Kawabe K,Kaku T,Igarashi H,Nakamura T,Takayanagi R

更新日期：2008-11-14 00:00:00

abstract：AIM:To investigate whether Dihydromyricetin (DHM) inhibits cell proliferation and promotes apoptosis by downregulating Notch1 expression. METHODS:The correlation between Notch1 and Hes1 (a Notch1 target molecule) expression in hepatoma samples was confirmed by qRT-PCR. In addition, MTT assays, flow cytometry and TUNEL...

journal_title：World journal of gastroenterology

authors： Lu CJ,He YF,Yuan WZ,Xiang LJ,Zhang J,Liang YR,Duan J,He YH,Li MY

更新日期：2017-09-14 00:00:00

abstract：AIM:To study the expression and serum level of HBxAg, Fas and FasL in tissues of HCC patients, and to assess the relationship between HBxAg and Fas/FasL system. METHODS:Tissues from 50 patients with HCC were tested for the expression of HBxAg, Fas and FasL by S-P immunohistochemistry. Serum levels of sFas/sFasL and HB...

journal_title：World journal of gastroenterology

authors： Wang XZ,Chen XC,Chen YX,Zhang LJ,Li D,Chen FL,Chen ZX,Chen HY,Tao QM

更新日期：2003-12-01 00:00:00

abstract：AIM:To evaluate the clinical usefulness of (18)F-fluorodeoxyglucose positron emission and computed tomography ((18)F-FDG PET/CT) in restaging of esophageal cancer after surgical resection and radiotherapy. METHODS:Between January 2007 and Aug 2008, twenty histopathologically diagnosed esophageal cancer patients underw...

journal_title：World journal of gastroenterology

authors： Sun L,Su XH,Guan YS,Pan WM,Luo ZM,Wei JH,Zhao L,Wu H

更新日期：2009-04-21 00:00:00

abstract：:AIM:To evaluate a culture system for bile acid formation in primary human hepatocytes in comparison with HepG2 cells.METHODS:Hepatocytes were isolated from normal human liver tissue and we re cultured in serum-free William's E medium.The medium was collected and re newed every 24 h. Bile acids and their precursors in ...

journal_title：World journal of gastroenterology

authors： Einarsson C,Ellis E,Abrahamsson A,Ericzon BG,Bjorkhem I,Axelson M

更新日期：2000-08-01 00:00:00

abstract：:The continued need to develop less invasive alternatives to surgical and radiologic interventions has driven the development of endoscopic ultrasound (EUS)-guided treatments. These include EUS-guided drainage of pancreatic fluid collections, EUS-guided necrosectomy, EUS-guided cholangiography and biliary drainage, EUS...

journal_title：World journal of gastroenterology

authors： Fabbri C,Luigiano C,Lisotti A,Cennamo V,Virgilio C,Caletti G,Fusaroli P

更新日期：2014-07-14 00:00:00

abstract：:The incidence of gastric cancer remains high in South Korea. Upper gastrointestinal (GI) endoscopy, i.e., esophagogastroduodenoscopy (EGD), has a higher diagnostic specificity and sensitivity than the upper GI series. Additionally, EGD has the ability to biopsy, through taking a tissue of the pathologic lesion. Succes...

journal_title：World journal of gastroenterology

authors： Lee SH,Park YK,Cho SM,Kang JK,Lee DJ

更新日期：2015-01-21 00:00:00

abstract：AIM:To investigate the effects of autoantibodies against beta(1)-adrenoceptor in hepatitis virus myocarditis on action potential and L-type Ca(2+) currents. METHODS:Fifteen samples of autoantibodies against beta(1)-adrenoceptor positive sera of patients with hepatitis virus myocarditis were obtained and IgGs were puri...

journal_title：World journal of gastroenterology

authors： Liu K,Liao YH,Wang ZH,Li SL,Wang M,Zeng LL,Tang M

更新日期：2004-04-15 00:00:00

abstract：AIM:To investigate the impact of arachidonic acid (AA) and docosahexaenoic acid (DHA) and their combination on colon cancer cell growth. METHODS:The LS-174T colon cancer cell line was used to study the role of the prostaglandin precursor AA and the omega-3 polyunsaturated fatty acid DHA on cell growth. Cell viability ...

journal_title：World journal of gastroenterology

authors： Habbel P,Weylandt KH,Lichopoj K,Nowak J,Purschke M,Wang JD,He CW,Baumgart DC,Kang JX

更新日期：2009-03-07 00:00:00

abstract：:The motor function of the gastrointestinal tract has primarily been studied using manometry and radiography, though more indirect tests have also been applied. Manometry and radiography do not provide detailed information about the muscle properties as can be assessed from studies of muscle properties in muscle strips...

journal_title：World journal of gastroenterology

authors： Gregersen H,Liao D

更新日期：2006-05-14 00:00:00

abstract：AIM:To evaluate the efficacy of 5 compared to 10 granulocyteaphaeresis sessions in patients with active steroid-dependent ulcerative colitis. METHODS:In this pilot, prospective, multicenter randomized trial, 20 patients with moderately active steroid-dependent ulcerative colitis were randomized to 5 or 10 granulocytea...

journal_title：World journal of gastroenterology

authors： Ricart E,Esteve M,Andreu M,Casellas F,Monfort D,Sans M,Oudovenko N,Lafuente R,Panes J

更新日期：2007-04-21 00:00:00

abstract：AIM:To investigate the expression of insulin-like growth factor binding protein-2 (IGFBP-2) in gastric carcinoma and its clinical significance and to explore its relationship with cell proliferation. METHODS:Expressions of IGFBP-2 and Ki-67 in 118 cases of gastric carcinoma and 40 cases of normal gastric mucosa were d...

journal_title：World journal of gastroenterology

authors： Shi LH,Zhu XQ,Zhao GH,Xia YB,Zhang YS

更新日期：2006-10-21 00:00:00

abstract：AIM:To clarify the relationship between circumferential resection margin status and local and distant recurrence as well as survival of patients with middle and lower rectal carcinoma. The relationship between circumferential resection margin status and clinicopathologic characteristics of middle and lower rectal carci...

journal_title：World journal of gastroenterology

authors： Wu ZY,Wan J,Li JH,Zhao G,Peng L,Yao Y,Du JL,Liu QF,Wang ZD,Huang ZM,Lin HH

更新日期：2007-06-28 00:00:00

abstract：:A female patient with anemia and hypoalbuminemia was admitted to our hospital due to an over 20-year history of recurrent dizziness, fatigue and ankle edema. She was diagnosed as multiple chronic non-specific ulcer of the small intestine characterized by non-specific histology and persistent gastrointestinal bleeding....

journal_title：World journal of gastroenterology

authors： Chen Y,Ma WQ,Chen JM,Cai JT

更新日期：2010-02-14 00:00:00

abstract：:Liver cancer is one of the world's most common cancers and the second leading cause of cancer deaths. Hepatocellular carcinoma (HCC), a primary hepatic cancer, accounts for 90%-95% of liver cancer cases. The pathogenesis of HCC consists of a stepwise process of liver damage that extends over decades, due to hepatitis,...

journal_title：World journal of gastroenterology

authors： Lu JW,Ho YJ,Yang YJ,Liao HA,Ciou SC,Lin LI,Ou DL

更新日期：2015-11-14 00:00:00

abstract：AIM:To study the origin of calcium necessary for agonist-induced contraction of the distal colon in rats. METHODS:The change in intracellular calcium concentration ([Ca2+]i) evoked by elevating external Ca2+ was detected by fura 2/AM fluorescence. Contractile activity was measured with a force displacement transducer....

journal_title：World journal of gastroenterology

authors： Zhou H,Kong DH,Pan QW,Wang HH

更新日期：2008-02-21 00:00:00

abstract：AIM:To evaluate the efficacy and the safety of combined 5-Fluorouracil, irinotecan, bevacizumab and sirolimus in refractory advanced colorectal carcinoma. METHODS:We initiated a regimen with at day 1 an injection (iv) of bevacizumab at 5 mg/kg, followed by 180 mg/m(2) irinotecan, followed by Leucovorin 400 mg/m(2), fo...

journal_title：World journal of gastroenterology

authors： Ghiringhelli F,Guiu B,Chauffert B,Ladoire S

更新日期：2009-09-14 00:00:00

abstract：AIM:To evaluate the significance of hsp90alpha expression in human gastric cancer tissues. METHODS:Immunohistochemical staining was used in clinical specimens from 33 cases of gastric cancer and 33 cases of gastritis with rabbit anti-human hsp90alpha multi-clonal antibody in order to explore the relationship between t...

journal_title：World journal of gastroenterology

authors： Zuo DS,Dai J,Bo AH,Fan J,Xiao XY

更新日期：2003-11-01 00:00:00

abstract：AIM:To investigate functional change of dendritic cells (DCs) derived from allogeneic partial liver graft undergoing acute rejection in rats. METHODS:Allogeneic (SD rat to LEW rat) whole and 50 % partial liver transplantation were performed. DCs from liver grafts 0 hr and 4 days after transplantation were isolated and...

journal_title：World journal of gastroenterology

authors： Xu MQ,Yao ZX

更新日期：2003-01-01 00:00:00

abstract：:Functional gastrointestinal disorders (FGID) are heterogeneous disorders with a variety of clinical manifestations, primarily defined by signs and symptoms rather than a definite underlying cause. Their pathophysiology remains obscure and, although it is expected to differ according to the specific FGID, disruptions i...

journal_title：World journal of gastroenterology

authors： Koutouratsas T,Kalli T,Karamanolis G,Gazouli M

更新日期：2019-02-07 00:00:00

abstract：AIM:To investigate the accuracy of endoscopic or biopsy diagnoses of superficial nonampullary duodenal epithelial tumors (NADETs). METHODS:Clinicopathological data were reviewed for 84 superficial NADETs from 74 patients who underwent surgery or endoscopic resection between September 2002 and August 2014 at a single p...

journal_title：World journal of gastroenterology

authors： Kakushima N,Kanemoto H,Sasaki K,Kawata N,Tanaka M,Takizawa K,Imai K,Hotta K,Matsubayashi H,Ono H

更新日期：2015-05-14 00:00:00

abstract：:Colorectal cancer metastasizes predictably, with liver predominance in most cases. Because liver involvement has been shown to be a major determinant of survival in this population, liver-directed therapies are increasingly considered even in cases where there is (limited) extrahepatic disease. Unfortunately, these pa...

journal_title：World journal of gastroenterology

authors： Sag AA,Selcukbiricik F,Mandel NM

更新日期：2016-03-21 00:00:00

abstract：AIM:To clarify the strategy for early diagnosis of pancreaticobiliary maljunction (PBM) without biliary dilatation and to pathologically examine gallbladder before cancer develops. METHODS:The anatomy of the union of the pancreatic and bile ducts was assessed by using endoscopic retrograde cholangiopancreatography (ER...

journal_title：World journal of gastroenterology

authors： Takuma K,Kamisawa T,Tabata T,Hara S,Kuruma S,Inaba Y,Kurata M,Honda G,Tsuruta K,Horiguchi S,Igarashi Y

更新日期：2012-07-14 00:00:00

abstract：:AIM:To explore the expression and changes of hepatoma specific alkaline phospatase (ALP) in rats during canceration.METHODS:The ALPs and isoenzymes of rat livers and sera were investigated in SD hepatomas induced with 0.05% 2-fluoenylacetamide (2-FAA).RESULTS: By pathological examination and biochemical analysis. ALPs...

journal_title：World journal of gastroenterology

authors： Xiao MB,Yao DF,Zhang H,Qiang H,Huang JF,Wei Q,Jiang F

更新日期：1998-08-01 00:00:00

abstract：AIM:To assess the risk of relapse in ulcerative colitis (UC) patients in clinical remission using mucosal status and fecal immunochemical test (FIT) results. METHODS:The clinical outcomes of 194 UC patients in clinical remission who underwent colonoscopy were based on evaluations of Mayo endoscopic subscores (MESs) an...

journal_title：World journal of gastroenterology

authors： Nakarai A,Kato J,Hiraoka S,Takashima S,Takei D,Inokuchi T,Sugihara Y,Takahara M,Harada K,Okada H

更新日期：2016-06-07 00:00:00

abstract：AIM:To compare the clinical efficacy of the second-generation H2RA lafutidine with that of lansoprazole in Japanese patients with mild gastroesophageal reflux disease (GERD). METHODS:Patients with symptoms of GERD and a diagnosis of grade A reflux esophagitis (according to the Los Angeles classification) were randomiz...

journal_title：World journal of gastroenterology

authors： Takenaka R,Okada H,Kawano S,Komazawa Y,Yoshinaga F,Nagata S,Inoue M,Komatsu H,Onogawa S,Kushiyama Y,Mukai S,Todo H,Okanobu H,Manabe N,Tanaka S,Haruma K,Kinoshita Y

更新日期：2016-06-21 00:00:00

abstract：AIM:To elucidate the expression of the apoptosis-associated molecules in human primary hepatocellular carcinoma (HCC) cells, and prepare the monoclonal antibodies (mAb) against the apoptosis-associated antigens of HCC cells. METHODS:Human HCC cell line HCC-9204 cells were induced apoptosis with 60 mL x L(-1) ethanol f...

journal_title：World journal of gastroenterology

authors： Yang LJ,Wang WL

更新日期：2002-10-01 00:00:00

abstract：AIM:To investigate the expression of cyclooxygenase-2 (COX-2) in gastric cancer and its relation with the liver metastasis and prognosis. METHODS:Expression of COX-2 mRNA and protein was examined in gastric cancer and its paired substantial normal tissue by semi-quantitative reverse transcription-polymerase chain reac...

journal_title：World journal of gastroenterology

authors： Yu JR,Wu YJ,Qin Q,Lu KZ,Yan S,Liu XS,Zheng SS

更新日期：2005-08-21 00:00:00