New perspectives of studying gastrointestinal muscle function.

abstract：AIM:To observe whether there are differences in the effects of electro-acupuncture (EA) and moxibustion (Mox) in rats with visceral hypersensitivity. METHODS:EA at 1 mA and 3 mA and Mox at 43 °C and 46 °C were applied to the Shangjuxu (ST37, bilateral) acupoints in model rats with visceral hypersensitivity. Responses ...

journal_title：World journal of gastroenterology

authors： Zhao JM,Li L,Chen L,Shi Y,Li YW,Shang HX,Wu LY,Weng ZJ,Bao CH,Wu HG

更新日期：2017-04-28 00:00:00

abstract：:Abnormal bone metabolism and dysfunction of the calcium-parathyroid hormone-vitamin D axis have been reported in patients with viral hepatitis. Some studies suggested a relationship between vitamin D and viral hepatitis. Genetic studies have provided an opportunity to identify the proteins that link vitamin D to the p...

journal_title：World journal of gastroenterology

authors： Lương Kv,Nguyễn LT

更新日期：2012-10-14 00:00:00

abstract：:In colon cancer, classic disease staging remains the key prognosis and treatment determinant. Although adjuvant chemotherapy has an established role in stage III colon cancer patients, in stage II it is still a subject of controversy due to its restriction to a small subgroup of patients with high-risk histopathologic...

journal_title：World journal of gastroenterology

authors： Saridaki Z,Souglakos J,Georgoulias V

更新日期：2014-06-14 00:00:00

abstract：:Pancreatic cancer is one of the most aggressive and difficult cancers to treat. Despite numerous research efforts, limited success has been achieved in the therapeutic management of patients with this disease. In the current review, we focus on one component of morphogenesis signaling, Hedgehog (Hh), with the aim of d...

journal_title：World journal of gastroenterology

authors： Onishi H,Katano M

更新日期：2014-03-07 00:00:00

abstract：AIM:To investigate the epidemiology of hepatitis B virus (HBV) and hepatitis C virus (HCV) infection in the two major ethnic groups in Kazakhstan. METHODS:A cross-sectional prospective study of HBV and HCV seroprevalence was performed among individuals born in Kazakhstan with no history of chronic hepatitis or liver d...

journal_title：World journal of gastroenterology

authors： Nurgalieva ZZ,Hollinger FB,Graham DY,Zhangabylova S,Zhangabylov A

更新日期：2007-02-28 00:00:00

abstract：BACKGROUND:Early diagnosis of hepatocellular carcinoma may help to ensure that patients have a chance for long-term survival; however, currently available biomarkers lack sensitivity and specificity. AIM:To characterize the serum metabolome of hepatocellular carcinoma in order to develop a new metabolomics diagnostic ...

journal_title：World journal of gastroenterology

authors： Zhou PC,Sun LQ,Shao L,Yi LZ,Li N,Fan XG

更新日期：2020-08-21 00:00:00

abstract：AIM:To investigate whether α-fetoprotein (AFP) and vascular endothelial growth factor receptor (VEGFR)-1 correlate with early recurrence of hepatoma/hepatocellular carcinoma (HCC). METHODS:From 2000 to 2005, 114 consecutive patients with HCC underwent primary curative hepatectomy. The mean age was 60.7 (8.7) years and...

journal_title：World journal of gastroenterology

authors： Kamiyama T,Takahashi M,Nakanishi K,Yokoo H,Kamachi H,Kobayashi N,Ozaki M,Todo S

更新日期：2012-01-28 00:00:00

abstract：:Hepatitis C is recognized as a major threat to global public health. The current treatment of patients with chronic hepatitis C is the addition of ribavirin to interferon-based therapy which has limited efficacy, poor tolerability, and significant expense. New treatment options that are more potent and less toxic are ...

journal_title：World journal of gastroenterology

authors： Khattab MA

更新日期：2009-07-28 00:00:00

abstract：AIM:To assess the effectiveness of endoscopic full-thickness resection (EFR) and laparoscopic surgery in the treatment of gastric stromal tumors arising from the muscularis propria. METHODS:Out of 62 gastric stromal tumors arising from the muscularis propria, each > 1.5 cm in diameter, 32 were removed by EFR, and 30 w...

journal_title：World journal of gastroenterology

authors： Huang LY,Cui J,Wu CR,Zhang B,Jiang LX,Xian XS,Lin SJ,Xu N,Cao XL,Wang ZH

更新日期：2014-07-07 00:00:00

abstract：BACKGROUND:Identifying predictors of therapeutic response is the cornerstone of personalized medicine. AIM:To identify predictors of long-term mucosal healing (MH) in patients with Crohn's disease (CD) treated with tumor necrosis factor α (TNF-α) inhibitors. METHODS:Prospective single center study. Consecutive patien...

journal_title：World journal of gastroenterology

authors： Alfaro I,Masamunt MC,Planell N,López-García A,Castro J,Gallego M,Barastegui R,Giner A,Vara A,Salas A,Ricart E,Panés J,Ordás I

更新日期：2019-04-14 00:00:00

abstract：:Anorectal melanoma is a very rare tumor with poor prognosis. Rectal bleeding is the most frequent symptom and surgical treatment ranges from local excision to radical abdominoperineal resection. We report a case of a 75-years-old male patient who presented with a history of recurrent rectal bleeding, and whose histopa...

journal_title：World journal of gastroenterology

authors： Balicevic D,Tomic K,Bekavac-Beslin M,Kovacevic I,Mijic A,Belicza M,Kruslin B

更新日期：2006-06-07 00:00:00

abstract：AIM:To investigate the prognostic impact of the metastatic lymph node ratio (MLR) in advanced gastric cancer from the cardia and fundus. METHODS:Two hundred and thirty-six patients with gastric cancer from the cardia and fundus who underwent D2 curative resection were analyzed retrospectively. The correlations between...

journal_title：World journal of gastroenterology

authors： Huang CM,Lin BJ,Lu HS,Zhang XF,Li P,Xie JW

更新日期：2008-07-21 00:00:00

abstract：AIM:To investigate the effects of short-term application of low-dose growth hormone on trace element metabolism and blood glucose in surgical patients. METHODS:A total of 48 consecutive patients undergoing abdominal operations were randomized to receive either subcutaneous rhGH (0.15 IU/kg) or placebo (menstruum) inje...

journal_title：World journal of gastroenterology

authors： Qian K,Wan Z,Hao LS,Zhang MM,Zhou Y,Wu XT

更新日期：2007-12-14 00:00:00

abstract：AIM:To summarize progress in the study of K-ras gene studies in pancreatic cancer and its potential clinical significance in screening test for early detection of pancreatic cancer, and to differentiate pancreatic cancer from chronic pancreatitis in recent decade. METHODS:Literature search (MEDLINE 1986-2003) was perf...

journal_title：World journal of gastroenterology

authors： Mu DQ,Peng YS,Xu QJ

更新日期：2004-02-15 00:00:00

abstract：:Tumor immunity proceeds through multiple processes, which consist of antigen presentation by antigen presenting cells (APCs) to educate effector cells and destruction by the effector cytotoxic cells. However, tumor immunity is frequently repressed at tumor sites. Malignantly transformed cells rarely survive the attack...

journal_title：World journal of gastroenterology

authors： Mukaida N,Nakamoto Y

更新日期：2018-05-07 00:00:00

abstract：AIM:gamma-glutamyl transpeptidase (GGT) has been reported as a virulence and colonizing factor of Helicobacter pylori (H pylori). This study examined the effect of GGT on the growth of H pylori. METHODS:Standard H pylori strain NCTC 11637 and 4 clinical isolates with different levels of GGT activity as measured by an ...

journal_title：World journal of gastroenterology

authors： Gong M,Ho B

更新日期：2004-10-15 00:00:00

abstract：AIM:To study the role of hepatic sinusoidal capillarization and perisinusoidal fibrosis in rats with alcohol-induced portal hypertension and to discuss the pathological mechanisms of alcohol-induced hepatic portal hypertension. METHODS:Fifty SD rats were divided into control group (n=20) and model group (n=30). Alcoho...

journal_title：World journal of gastroenterology

authors： Li J,Niu JZ,Wang JF,Li Y,Tao XH

更新日期：2005-11-07 00:00:00

abstract：:Systemic therapy for hepatocellular carcinoma (HCC) has markedly advanced since the survival benefit of a molecular targeted agent, sorafenib, were demonstrated in the SHARP and Asia Pacific trials in 2007. Treatment options for patients with advanced HCC increased by sorafenib, and long-term survival for patients wit...

journal_title：World journal of gastroenterology

authors： Kudo M

更新日期：2019-02-21 00:00:00

abstract：:A case of strangulation of the transverse colon in a traumatic left diaphragmatic hernia manifesting as pericarditis is reported. This is unusual because pericardial signs in traumatic diaphragmatic hernia have been previously described in association with direct pericardial injury. This is the only such case where el...

journal_title：World journal of gastroenterology

authors： Makhija R,Akoh JA

更新日期：2007-03-07 00:00:00

abstract：:Hepatoblastoma is the most common primary hepatic tumor of children. However, only a very few cases have been reported in adults. Most studies support treatment with chemotherapy followed by surgical resection. We present the first reported case of adult hepatoblastoma in Taiwan. A 52-year-old female suffered from sud...

journal_title：World journal of gastroenterology

authors： Ke HY,Chen JH,Jen YM,Yu JC,Hsieh CB,Chen CJ,Liu YC,Chen TW,Chan DC

更新日期：2005-10-21 00:00:00

abstract：AIM:To determine whether any changes have occurred on the patterns of colorectal cancer in China. METHODS:Data from 21 Chinese articles published from 1980 to 1999, were used to analyze the time trend of colorectal cancer according to the patients' age at diagnosis, sex, the site of the tumor, stage, and the pathology...

journal_title：World journal of gastroenterology

authors： Li M,Gu J

更新日期：2005-08-14 00:00:00

abstract：:AIM:To explore the expression and changes of hepatoma specific alkaline phospatase (ALP) in rats during canceration.METHODS:The ALPs and isoenzymes of rat livers and sera were investigated in SD hepatomas induced with 0.05% 2-fluoenylacetamide (2-FAA).RESULTS: By pathological examination and biochemical analysis. ALPs...

journal_title：World journal of gastroenterology

authors： Xiao MB,Yao DF,Zhang H,Qiang H,Huang JF,Wei Q,Jiang F

更新日期：1998-08-01 00:00:00

abstract：:Nestin is a class VI intermediate filament protein that was originally described as a neuronal stem cell marker during central nervous system (CNS) development, and is currently widely used in that capacity. Nestin is also expressed in non-neuronal immature or progenitor cells in normal tissues. Under pathological con...

journal_title：World journal of gastroenterology

authors： Ishiwata T,Matsuda Y,Naito Z

更新日期：2011-01-28 00:00:00

abstract：AIM:To investigate the association between TP53 Arg72Pro polymorphism and esophageal cancer (EC) risk using meta-analysis. METHODS:All eligible studies published before March 1, 2010 were selected by searching PubMed using keywords "p53" or "TP53", "polymorphism" or "variation", "esophageal" and "cancer" or "carcinoma...

journal_title：World journal of gastroenterology

authors： Jiang DK,Yao L,Wang WZ,Peng B,Ren WH,Yang XM,Yu L

更新日期：2011-03-07 00:00:00

abstract：:AIM:To study the anticarcinogenic effect and acute toxicity of liver targeting mitoxantrone nanospheres.METHODS:The anticarcinogenic effect of mitoxan-trone polybutylcyanoacrylate nanoparticles (DHAQ-PBCA-NP) was investigated by using heterotopic and orthotopic transplantation models of human hepatocellular carcinoma ...

journal_title：World journal of gastroenterology

authors： Zhang ZR,He Q,Liao GT,Bai SH

更新日期：1999-12-01 00:00:00

abstract：:The progressive loss of efficacy of standard eradication therapies has made the treatment of Helicobacter pylori (H. pylori) more challenging than ever. Endoscopic-guided antibiotic susceptibility testing had previously been suggested to guide treatment after failure of second-line therapies. However, its role has exp...

journal_title：World journal of gastroenterology

authors： Cammarota G,Ianiro G,Bibbò S,Di Rienzo TA,Masucci L,Sanguinetti M,Gasbarrini A

更新日期：2014-05-14 00:00:00

abstract：AIM:To assess the risk of relapse in ulcerative colitis (UC) patients in clinical remission using mucosal status and fecal immunochemical test (FIT) results. METHODS:The clinical outcomes of 194 UC patients in clinical remission who underwent colonoscopy were based on evaluations of Mayo endoscopic subscores (MESs) an...

journal_title：World journal of gastroenterology

authors： Nakarai A,Kato J,Hiraoka S,Takashima S,Takei D,Inokuchi T,Sugihara Y,Takahara M,Harada K,Okada H

更新日期：2016-06-07 00:00:00

abstract：AIM:To investigate the effects of exogenous melatonin on bacterial translocation and apoptosis in a rat ulcerative colitis model. METHODS:Rats were randomly assigned to three groups: group I: control, group II: experimental colitis, group III: colitis plus melatonin treatment. On d 11 after colitis, plasma tumor necro...

journal_title：World journal of gastroenterology

authors： Akcan A,Kucuk C,Sozuer E,Esel D,Akyildiz H,Akgun H,Muhtaroglu S,Aritas Y

更新日期：2008-02-14 00:00:00

abstract：:Alterations of normal function of interstitial cells of Cajal (ICC) are reported in many intestinal disorders. Diagnosis of their involvement is rare (infrequent), but necessary to propose a specific treatment. This article reviews the place of ICC in the pathogenesis of achalasia, gastroesophageal reflux disease, inf...

journal_title：World journal of gastroenterology

authors： Negreanu LM,Assor P,Mateescu B,Cirstoiu C

更新日期：2008-11-07 00:00:00

abstract：:Hepatitis C virus (HCV) affects 130-210 million people worldwide and is one of the major risk factors for hepatocellular carcinoma. Globally, at least one third of hepatocellular carcinoma cases are attributed to HCV infection, and 350000 people died from HCV related diseases per year. There is a great geographical va...

journal_title：World journal of gastroenterology

authors： Lee MH,Yang HI,Yuan Y,L'Italien G,Chen CJ

更新日期：2014-07-28 00:00:00