Contribution of ghrelin to functional gastrointestinal disorders' pathogenesis.

abstract：AIM:To determine the expression of c-fos in gastric myenteric plexus and spinal cord of rats with cervical spondylosis and its clinical significance. METHODS:A cervical spondylosis model was established in rats by destroying the stability of cervical posterior column, and the cord segments C(4-6) and gastric antrum we...

journal_title：World journal of gastroenterology

authors： Song PS,Kong KM,Niu CY,Qi WL,Wu LF,Wang XJ,Han W,Huang K,Chen ZF

更新日期：2005-01-28 00:00:00

abstract：:Functional dyspepsia is a common clinical condition characterised by chronic or recurrent upper abdominal pain or discomfort commonly associated with a variety of associated gastrointestinal symptoms and a normal endoscopy. To standardise research-based approaches, an initial categorisation of into sub groups was agre...

journal_title：World journal of gastroenterology

authors： Baker G,Fraser RJ,Young G

更新日期：2006-05-07 00:00:00

abstract：:Pernicious anemia (PA) is a macrocytic anemia that is caused by vitamin B(12) deficiency, as a result of intrinsic factor deficiency. PA is associated with atrophic body gastritis (ABG), whose diagnosis is based on histological confirmation of gastric body atrophy. Serological markers that suggest oxyntic mucosa damag...

journal_title：World journal of gastroenterology

authors： Lahner E,Annibale B

更新日期：2009-11-07 00:00:00

abstract：AIM:To compare the results for endoscopic ultrasound (EUS)-guided drainage of clear fluid pancreatic pseudocysts with the results for abscess drainage. METHODS:All patients referred for endoscopic drainage of a fluid collection were prospectively included. The outcome was recorded. RESULTS:Altogether 26 pseudocysts o...

journal_title：World journal of gastroenterology

authors： Sadik R,Kalaitzakis E,Thune A,Hansen J,Jönson C

更新日期：2011-01-28 00:00:00

abstract：AIM:To unravel the differences between systematic inflammatory response syndrome (SIRS) of acute pancreatitis compared to the same syndrome in sepsis. METHODS:Twenty-five patients were enrolled, 12 with sepsis and 13 acute pancreatitis. After diagnosis 20 mL blood was sampled. Half were assayed for isolation of monocy...

journal_title：World journal of gastroenterology

authors： Koussoulas V,Tzivras M,Karagianni V,Spyridaki E,Plachouras D,Giamarellou H,Giamarellos-Bourboulis EJ

更新日期：2006-11-07 00:00:00

abstract：AIM:To examine the effect of hepatitis C virus (HCV) structural mimics of regulatory regions of the genome on HCV replication. METHODS:HCV RNA structural mimics were constructed and tested in a HCV genotype 1b aBB7 replicon, and a Japanese fulminant hepatitis-1 (JFH-1) HCV genotype 2a infection model. All sequences we...

journal_title：World journal of gastroenterology

authors： Smolic R,Smolic M,Andorfer JH,Wu CH,Smith RM,Wu GY

更新日期：2010-05-07 00:00:00

abstract：AIM:To investigate the effect of Danzhijiangtang capsule (DJC) on monocyte chemoattractant protein-1 (MCP-1) mRNA expression in newly diagnosed type 2 diabetes mellitus (T2DM) subclinical vascular lesions. METHODS:Sixty-two patients with newly diagnosed T2DM subclinical vascular lesions were randomly divided into a co...

journal_title：World journal of gastroenterology

authors： Fang ZH,Liu Y,Bao TT,Ni YQ,Liu J,Shi GB,Wu JP,Yang JP,Zhang H

更新日期：2013-05-21 00:00:00

abstract：AIM:To evaluate the influence of multiple samplings during esophagogastroduodenoscopy (EGD) on the accuracy of the rapid urease test, and the validity of newly developed rapid urease tests, HelicotecUT plus test and HelicotecUT test, CLO test and ProntoDry test. METHODS:A total of 355 patients undergoing EGD for dyspe...

journal_title：World journal of gastroenterology

authors： Hsu WH,Wang SS,Kuo CH,Chen CY,Chang CW,Hu HM,Wang JY,Yang YC,Lin YC,Wang WM,Wu DC,Wu MT,Kuo FC

更新日期：2010-06-21 00:00:00

abstract：:H. pylori is probably the most prevalent human pathogen worldwide. Since it was initially suggested in 1983 by Marshall and Warren to be implicated in gastritis and peptic ulcer disease, H. pylori has also been implicated in gastric carcinoma and was classified as a class I carcinogen. In the last two decades, a notew...

journal_title：World journal of gastroenterology

authors： Beswick EJ,Suarez G,Reyes VE

更新日期：2006-09-21 00:00:00

abstract：BACKGROUND:End-stage liver disease caused by non-alcoholic steatohepatitis (NASH) is the second leading indication for liver transplantation. To date, only moderately effective pharmacotherapies exist to treat NASH. Understanding the pathogenesis of NASH is therefore crucial for the development of new therapies. The in...

journal_title：World journal of gastroenterology

authors： Bluemel S,Wang Y,Lee S,Schnabl B

更新日期：2020-09-07 00:00:00

abstract：:The incidence of obesity has dramatically increased in recent years. Consequently, obesity and associated disorders such as nonalcoholic fatty liver disease constitute a serious problem. Therefore, the contribution of adipose tissue to metabolic homeostasis has become a focus of interest. In this review, we discuss th...

journal_title：World journal of gastroenterology

authors： Tarantino G,Caputi A

更新日期：2011-09-07 00:00:00

abstract：AIM:To investigate the expression frequency of endocan in colorectal cancer and analyze the relationship between endocan expression and clinical parameters and to study the role of endocan in colorectal carcinogenesis. METHODS:Expression of endocan in 72 tumor tissue samples of colorectal cancer as well as in 27 norma...

journal_title：World journal of gastroenterology

authors： Zuo L,Zhang SM,Hu RL,Zhu HQ,Zhou Q,Gui SY,Wu Q,Wang Y

更新日期：2008-07-28 00:00:00

abstract：AIM:To compare the utility of single-balloon colonoscopy (SBC) or double-balloon colonoscopy (DBC) for difficult colonoscopies. METHODS:Between August 2008 and June 2010, patients in whom total colonoscopy failed within 30 min of insertion were assigned randomly to undergo either SBC or DBC. No sedatives were used. Af...

journal_title：World journal of gastroenterology

authors： Yamada A,Watabe H,Takano N,Togo G,Yamaji Y,Yoshida H,Kawabe T,Omata M,Koike K

更新日期：2013-08-07 00:00:00

abstract：AIM:To characterize the protein files in blood from same patients with esophageal squamous cell carcinoma (ESCC) before and after operation at the high-incidence area for ESCC in Henan Province, China. METHODS:Two-dimensional electrophoresis, silver staining and ImageMaster 2-DE analysis software were applied to the d...

journal_title：World journal of gastroenterology

authors： An JY,Fan ZM,Zhuang ZH,Qin YR,Gao SS,Li JL,Wang LD

更新日期：2004-11-15 00:00:00

abstract：AIM:To investigate and characterise patients with chronic hepatitis C virus (HCV) infection presenting with hepatocellular carcinoma (HCC) in the absence of cirrhosis. METHODS:Patients with chronic hepatitis C infection without cirrhosis presenting with HCC over a 2-year period were identified. The clinical case notes...

journal_title：World journal of gastroenterology

authors： Nash KL,Woodall T,Brown AS,Davies SE,Alexander GJ

更新日期：2010-08-28 00:00:00

abstract：AIM:To investigate the effects of extended lymphadenectomy and postoperative chemotherapy on gastric cancer without lymph node metastasis. METHODS:Clinical data of 311 node-negative gastric cancer patients who underwent potentially curative gastrectomy with more than 15 lymph nodes resected, from January 2002 to Decem...

journal_title：World journal of gastroenterology

authors： Xue Q,Wang XN,Deng JY,Zhang RP,Liang H

更新日期：2013-09-07 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a complex, immune-mediated gastrointestinal disorder with ill-defined etiology, multifaceted diagnostic criteria, and unpredictable treatment response. Innovations in IBD diagnostics, including developments in genomic sequencing and molecular analytics, have generated tremendous int...

journal_title：World journal of gastroenterology

authors： Kohli A,Holzwanger EA,Levy AN

更新日期：2020-11-28 00:00:00

abstract：:Anti-tumor necrosis factor alpha (TNF-alpha) inhibitors are effective in the treatment of various inflammatory rheumatic conditions. Increased risks of serious infections are the major issues concerning the long-term safety of these agents. We present a case of a young male Behcet's patient whose disease was complicat...

journal_title：World journal of gastroenterology

authors： Sari I,Birlik M,Gonen C,Akar S,Gurel D,Onen F,Akkoc N

更新日期：2008-05-14 00:00:00

abstract：AIM:To evaluate tumor necrosis factor-α converting enzyme (TACE) methylation status in patients with chronic hepatitis B (CHB). METHODS:Eighty patients with hepatitis B e antigen (HBeAg)-positive CHB, 80 with HBeAg-negative CHB, and 40 healthy controls (HCs) were randomly enrolled in this study. Genomic DNA was extrac...

journal_title：World journal of gastroenterology

authors： Wang ZL,Gao S,Li XY,Sun FK,Li F,Fan YC,Wang K

更新日期：2015-07-21 00:00:00

abstract：AIM:To investigate H(+), K(+)-ATPase inhibition, anti-H pylori, antioxidant, and the in vivo antiulcer potential of a pectic polysaccharide from Swallow root (Decalepis hamiltonii; SRPP). METHODS:SRPP, with known sugar composition [rhamnose: arabinose: xylose: galactose in the ratio of 16:50:2:32 (w/w), with 141 mg/g ...

journal_title：World journal of gastroenterology

authors： Srikanta B,Siddaraju M,Dharmesh S

更新日期：2007-10-21 00:00:00

abstract：AIM:To determine the expression characteristics of connective tissue growth factor (CTGF/CCN2) in human hepatocellular carcinoma (HCC) in histology and to elucidate the roles of CCN2 on hepatoma cell cycle progression and metastasis in vitro. METHODS:Liver samples from 36 patients (who underwent hepatic resection for ...

journal_title：World journal of gastroenterology

authors： Xiu M,Liu YH,Brigstock DR,He FH,Zhang RJ,Gao RP

更新日期：2012-12-21 00:00:00

abstract：AIM:To evaluate clinical presentation, etiology, complications and response to treatment in elderly patients with acute cholangitis. METHODS:Demographics, etiology of biliary obstruction, clinical features, complications and associated systemic diseases of 175 patients with acute cholangitis were recorded. Endoscopic ...

journal_title：World journal of gastroenterology

authors： Agarwal N,Sharma BC,Sarin SK

更新日期：2006-10-28 00:00:00

abstract：:Management of hepatocellular carcinoma (HCC) with portal vein thrombosis (PVT) is complex and requires an understanding of multiple therapeutic options. PVT is present in 10%-40% of HCC at the time of diagnosis, and is an adverse prognostic factor. Management options are limited, as transplantation is generally contra...

journal_title：World journal of gastroenterology

authors： Quirk M,Kim YH,Saab S,Lee EW

更新日期：2015-03-28 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) has been recognized as a major health burden. The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity, unhealthy dietary pattern, and sedentary lifestyle. The efficacy and safety profile of pharmacotherapy in the treatment of NAFLD remains uncertai...

journal_title：World journal of gastroenterology

authors： Zelber-Sagi S,Ratziu V,Oren R

更新日期：2011-08-07 00:00:00

abstract：AIM:To study the effects of drug treatment on hyperplastic gastric polyps infected with Helicobacter pylori (H pylori). METHODS:Forty-eight patients with hyperplastic gastric polyps (3-10 mm in diameter) infected with H pylori were randomly assigned to a treatment group (n = 24) which received proton-pump inhibitor (o...

journal_title：World journal of gastroenterology

authors： Ji F,Wang ZW,Ning JW,Wang QY,Chen JY,Li YM

更新日期：2006-03-21 00:00:00

abstract：AIM:To evaluate the Z-line visualization by the PillCam SB2 using three different ingestion protocols. METHODS:Ninety consecutive patients undergoing small bowel capsule endoscopy (SBCE) between January and May 2008 were included in the study. They swallowed the capsule in the standing (Group A = 30), supine (Group B ...

journal_title：World journal of gastroenterology

authors： Fernandez-Urien I,Borobio E,Elizalde I,Irisarri R,Vila JJ,Urman JM,Jimenez J

更新日期：2010-01-07 00:00:00

abstract：AIM:To investigate the dynamic features of insulin-like growth factor-I receptor (IGF-IR) expression in rat hepatocarcinogenesis, and the relationship between IGF-IR and hepatocytes malignant transformation at mRNA or protein level. METHODS:Hepatoma models were made by inducing with 2-fluorenylacetamide (2-FAA) on mal...

journal_title：World journal of gastroenterology

authors： Yan XD,Yao M,Wang L,Zhang HJ,Yan MJ,Gu X,Shi Y,Chen J,Dong ZZ,Yao DF

更新日期：2013-09-28 00:00:00

abstract：AIM:To retrospectively evaluate the imaging features of pancreatic intraductal papillary mucinous neoplasms (IPMNs) in multi-detector row computed tomography (MDCT). METHODS:A total of 20 patients with pathologically-confirmed intraductal papillary mucinous neoplasms (IPMNs) were included in this study. Axial MDCT ima...

journal_title：World journal of gastroenterology

authors： Tan L,Zhao YE,Wang DB,Wang QB,Hu J,Chen KM,Deng XX

更新日期：2009-08-28 00:00:00

abstract：AIM:To prospectively present our initial experience with totally laparoscopic transhiatal esophagogastrectomies for benign diseases of the cardia and distal esophagus. METHODS:Laparoscopic gastric mobilization and tubularization combined with transhiatal esophageal dissection and intrathoracic esophagogastric anastomo...

journal_title：World journal of gastroenterology

authors： Dulucq JL,Wintringer P,Mahajna A

更新日期：2007-01-14 00:00:00

abstract：AIM:To examine the epidemiology of hepatitis B virus carrier status (HBVC) and sonographic fatty liver (SFL) in Taiwanese adults, and to evaluate their possible interaction in inducing liver damage (LD). >From an epidemiological viewpoint, we analyzed previous studies which indicated that fatty liver sensitizes host im...

journal_title：World journal of gastroenterology

authors： Lin YC,Hsiao ST,Chen JD

更新日期：2007-03-28 00:00:00