Overexpression of insulin-like growth factor-I receptor as a pertinent biomarker for hepatocytes malignant transformation.

abstract：AIM:To elucidate the effect of angiogenesis inhibitor, Linomide, on tumor growth and metastasis in nude mice implanted with human gastric cancer. METHODS:A metastatic model of gastric cancer was established using orthotopic implantation of histologically intact tumor tissues into the gastric wall of nude mice. Linomid...

journal_title：World journal of gastroenterology

authors： Tao HQ,Lin YZ,Yin HR,Gu QL,Zhu ZG,Yao M

更新日期：1997-09-15 00:00:00

abstract：AIM:To assess B1a cell expression in the rectal mucosa of ulcerative colitis (UC) patients in comparison with healthy controls. METHODS:Rectal mucosa biopsies were collected from 15 UC patients and 17 healthy controls. CD5(+) B cells were analysed by three colour flow cytometry from rectal mucosal samples after mechan...

journal_title：World journal of gastroenterology

authors： Polese L,Boetto R,De Franchis G,Angriman I,Porzionato A,Norberto L,Sturniolo GC,Macchi V,De Caro R,Merigliano S

更新日期：2012-01-14 00:00:00

abstract：AIM:To examine the association between obesity-related adipokines (adiponectin, leptin, resistin, interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) and colorectal cancer (CRC) risk. METHODS:Serum levels of adipokines were measured in 100 CRC patients and age- and sex-matched controls for the data analysis. Unc...

journal_title：World journal of gastroenterology

authors： Joshi RK,Kim WJ,Lee SA

更新日期：2014-06-28 00:00:00

abstract：AIM:To evaluate when Helicobacter pylori (H. pylori) eradication therapy (ET) should be started in patients with peptic ulcer bleeding (PUB). METHODS:Clinical data concerning adults hospitalized with PUB were retrospectively collected and analyzed. Age, sex, type and stage of peptic ulcer, whether endoscopic therapy w...

journal_title：World journal of gastroenterology

authors： Yoon H,Lee DH,Jang ES,Kim J,Shin CM,Park YS,Hwang JH,Kim JW,Jeong SH,Kim N

更新日期：2015-02-28 00:00:00

abstract：AIM:To investigate anti-apoptotic effects of glycyrrhizic acid (GA) against fibrosis in carbon tetrachloride (CCl4)-induced liver injury and its contributing factors. METHODS:Liver fibrosis was induced by administration of CCl4 for 8 wk. Pathological changes in the liver of rats were examined by hematoxylin-eosin stai...

journal_title：World journal of gastroenterology

authors： Liang B,Guo XL,Jin J,Ma YC,Feng ZQ

更新日期：2015-05-07 00:00:00

abstract：AIM:To evaluate the association between liver stiffness (LS) prior to the initiation of dual/triple therapy and viral response. METHODS:LS was measured in all patients before treatment was administered. The therapeutic approach was based on hepatic, virological, and immunological evaluations and considered the fact th...

journal_title：World journal of gastroenterology

authors： Stasi C,Piluso A,Arena U,Salomoni E,Montalto P,Monti M,Boldrini B,Corti G,Marra F,Laffi G,Milani S,Zignego AL

更新日期：2015-03-14 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is known for its poor prognosis. Most of the patients are diagnosed with advanced stages, when no curative treatment is available. Currently, despite extensive clinical research on PDA, the median overall survival remains short. Diagnosis delay and primary chemo-resistance due to...

journal_title：World journal of gastroenterology

authors： Lamarca A,Feliu J

更新日期：2014-06-28 00:00:00

abstract：:One potential option for the management of refractory gastro-esophageal reflux disease (GERD) is the delivery of radiofrequency energy to the gastro-esophageal junction (Stretta). This endoscopic therapy is safe, effective, durable, and repeatable if necessary and serves an unmet need for many GERD sufferers. Stretta ...

journal_title：World journal of gastroenterology

authors： Triadafilopoulos G

更新日期：2014-06-28 00:00:00

abstract：:Poorly differentiated endocrine carcinoma (PDEC) of the pancreas is a rare and aggressive tumor. First-line treatment is commonly a combination of etoposide and cisplatin, but there is no consensus regarding further treatment recommendations. In this report, we describe a case of pancreatic PDEC treated with gemcitabi...

journal_title：World journal of gastroenterology

authors： Nakazuru S,Yoshio T,Suemura S,Itoh M,Araki M,Yoshioka C,Ohta M,Sueyoshi Y,Ohta T,Hasegawa H,Morita K,Toyama T,Kuzushita N,Kodama Y,Mano M,Mita E

更新日期：2010-08-14 00:00:00

abstract：AIM:To conduct a multicentre retrospective review of virological response rates in Asians infected with genotype 1 chronic hepatitis C (CHC) treated with combination interferon and ribavirin and then to compare their responses to that among Caucasians. METHODS:Asian patients infected with genotype 1 CHC treated at 4 A...

journal_title：World journal of gastroenterology

authors： Yan KK,Guirgis M,Dinh T,George J,Dev A,Lee A,Zekry A

更新日期：2008-06-07 00:00:00

abstract：:Duodenal polyps or lesions are uncommonly found on upper endoscopy. Duodenal lesions can be categorized as subepithelial or mucosally-based, and the type of lesion often dictates the work-up and possible therapeutic options. Subepithelial lesions that can arise in the duodenum include lipomas, gastrointestinal stromal...

journal_title：World journal of gastroenterology

authors： Gaspar JP,Stelow EB,Wang AY

更新日期：2016-01-14 00:00:00

abstract：:Autoimmune hepatitis (AIH) is an unresolving progressive liver disease of unknown etiology characterized by hypergammaglobulinemia, autoantibodies detection and interface hepatitis. Due to the absence of specific diagnostic markers and the large heterogeneity of its clinical, laboratory and histological features, AIH ...

journal_title：World journal of gastroenterology

authors： Gatselis NK,Zachou K,Koukoulis GK,Dalekos GN

更新日期：2015-01-07 00:00:00

abstract：AIM:To determine the clinical effectiveness of intense psychological support to physical activity (PA) in nonalcoholic fatty liver disease (NAFLD), compared with cognitive-behavioral treatment (CBT). METHODS:Twenty-two NAFLD cases received support to exercise, tailored to their motivational needs (PA group). The effec...

journal_title：World journal of gastroenterology

authors： Montesi L,Caselli C,Centis E,Nuccitelli C,Moscatiello S,Suppini A,Marchesini G

更新日期：2014-08-07 00:00:00

abstract：AIM:To study the protective effect of eukaryotic expression plasmid encoding augmenter of liver regeneration (ALR) on acute hepatic injury and hepatic failure in rats. METHODS:The PCR-amplified ALR gene was recombined with pcDNA3 plasmid, and used to treat rats with acute hepatic injury. The rats with acute hepatic in...

journal_title：World journal of gastroenterology

authors： Zhang LM,Liu DW,Liu JB,Zhang XL,Wang XB,Tang LM,Wang LQ

更新日期：2005-06-28 00:00:00

abstract：:Hypertriglyceridemic pancreatitis (HTGP) accounts for up to 10% of acute pancreatitis presentations in non-pregnant individuals and is the third most common cause of acute pancreatitis after alcohol and gallstones. There are a number of retrospective studies and case reports that have suggested a role for apheresis an...

journal_title：World journal of gastroenterology

authors： Saleh MA,Mansoor E,Cooper GS

更新日期：2017-10-28 00:00:00

abstract：:Functional dyspepsia is a common clinical condition characterised by chronic or recurrent upper abdominal pain or discomfort commonly associated with a variety of associated gastrointestinal symptoms and a normal endoscopy. To standardise research-based approaches, an initial categorisation of into sub groups was agre...

journal_title：World journal of gastroenterology

authors： Baker G,Fraser RJ,Young G

更新日期：2006-05-07 00:00:00

abstract：:External and internal rectal prolapse with their affiliated rectocele and enterocele, are associated with debilitating symptoms such as obstructed defecation, pelvic pain and faecal incontinence. Since perineal procedures are associated with a higher recurrence rate, an abdominal approach is commonly preferred. Despit...

journal_title：World journal of gastroenterology

authors： van Iersel JJ,Paulides TJ,Verheijen PM,Lumley JW,Broeders IA,Consten EC

更新日期：2016-06-07 00:00:00

abstract：:"Psychosocial stress" is an increasingly common concept in the challenging and highly-demanding modern society of today. Organic response to stress implicates two major components of the stress system, namely the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. Stress is anamnestically reported ...

journal_title：World journal of gastroenterology

authors： Vere CC,Streba CT,Streba LM,Ionescu AG,Sima F

更新日期：2009-06-28 00:00:00

abstract：:The gastrointestinal innate and adaptive immune system continuously faces the challenge of potent stimuli from the commensal microflora and food constituents. These local immune responses require a tight control, the outcome of which is in most cases the induction of tolerance. Local T cell immunity is an important co...

journal_title：World journal of gastroenterology

authors： Niess JH

更新日期：2008-09-07 00:00:00

abstract：AIM:To explore risk factors for lymph node metastases in early gastric cancer (EGC) and to confirm the appropriate range of lymph node dissection. METHODS:A total of 202 patients with EGC who underwent curative gastrectomy with lymphadenectomy in the Department of Surgery, Xinhua Hospital and Ruijin Hospital of Shangh...

journal_title：World journal of gastroenterology

authors： Ren G,Cai R,Zhang WJ,Ou JM,Jin YN,Li WH

更新日期：2013-05-28 00:00:00

abstract：AIM:To select the peptide mimicking the neutralization epitope of hepatitis E virus which bound to non-type-specific and conformational monoclonal antibodies (mAbs) 8C11 and 8H3 fromed 7-peptide phage display library, and expressed the peptide recombinant with HBcAg in E.coli, and to observe whether the recombinant HBc...

journal_title：World journal of gastroenterology

authors： Gu Y,Zhang J,Wang YB,Li SW,Yang HJ,Luo WX,Xia NS

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) can affect the entire gastrointestinal tract. Proximal small bowel (SB) lesions are associated with a significant risk of stricturing disease and multiple abdominal surgeries. The assessment of SB in patients with CD is therefore necessary because it may have a significant impact on prog...

journal_title：World journal of gastroenterology

authors： Le Berre C,Trang-Poisson C,Bourreille A

更新日期：2019-08-21 00:00:00

abstract：AIM:To investigate the risk indicators, pattern of clinical presentation and treatment strategy of superior mesenteric artery syndrome (SMAS) after scoliosis surgery. METHODS:From July 1997 to October 2003, 640 patients with adolescent scoliosis who had undergone surgical treatment were evaluated prospectively, and am...

journal_title：World journal of gastroenterology

authors： Zhu ZZ,Qiu Y

更新日期：2005-06-07 00:00:00

abstract：AIM:To develop a novel Helicobacter pylori (H. pylori) CagA antibody enzyme-linked immunosorbent assay (ELISA) suitable for detecting serum anti-CagA antibodies with high sensitivity. METHODS:Recombinant East Asian-type CagA protein was purified and immobilized for ELISA. Serum samples from 217 Vietnamese individuals ...

journal_title：World journal of gastroenterology

authors： Matsuo Y,Kido Y,Akada J,Shiota S,Binh TT,Trang TT,Dung HD,Tung PH,Tri TD,Thuan NP,Tam LQ,Nam BC,Khien VV,Yamaoka Y

更新日期：2017-01-07 00:00:00

abstract：AIM:To determine if exacerbation of pre-existing chronic colitis in Winnie (Muc2 mutant) mice induces colonic dysplasia. METHODS:Winnie mice and C57BL6 as a genotype control, were administered 1% w/v dextran sulphate sodium (DSS) orally, followed by drinking water alone in week-long cycles for a total of three cycles....

journal_title：World journal of gastroenterology

authors： Randall-Demllo S,Fernando R,Brain T,Sohal SS,Cook AL,Guven N,Kunde D,Spring K,Eri R

更新日期：2016-10-07 00:00:00

abstract：:Investigation of the possible role of Campylobacter concisus (C. concisus) in inflammatory bowel disease (IBD) is an emerging research area. Despite the association found between C. concisus and IBD, it has been difficult to explain how C. concisus, a bacterium that is commonly present in the human oral cavity, may co...

journal_title：World journal of gastroenterology

authors： Zhang L,Lee H,Grimm MC,Riordan SM,Day AS,Lemberg DA

更新日期：2014-02-07 00:00:00

abstract：AIM:To evaluate the efficacy and safety of HL tablet extracted from magnolia officinalis for treating patients with nonalcoholic fatty liver disease (NAFLD). METHODS:Seventy-four patients with NAFLD diagnosed by ultrasonography were randomly assigned to 3 groups given high dose (400 mg) HL tablet, low dose (133.4 mg) ...

journal_title：World journal of gastroenterology

authors： Jeong JY,Sohn JH,Baek YH,Cho YK,Kim Y,Kim H

更新日期：2017-08-28 00:00:00

abstract：AIM:To evaluate spiral computed tomography (CT) including virtual gastroscopy for diagnosis of gastric carcinoma in comparison with upper gastrointestinal series (UGI), fiberoptic gastroscopy (FG) and histopathology. METHODS:Sixty patients with histologically proven gastric carcinoma (54 advanced and 6 early) were inc...

journal_title：World journal of gastroenterology

authors： Chen F,Ni YC,Zheng KE,Ju SH,Sun J,Ou XL,Xu MH,Zhang H,Marchal G

更新日期：2003-07-01 00:00:00

abstract：:This issue presents different new techniques aiming to increase our understanding of the gastrointestinal system and to improve treatment. The technologies cover selected methods to evoke and assess gut pain, new methods for imaging and physiological measurements, histochemistry, pharmacological modelling etc. There i...

journal_title：World journal of gastroenterology

authors： Drewes AM,Gregersen H

更新日期：2009-01-14 00:00:00

abstract：:Cancer patients have unique problems associated with hepatitis C virus (HCV) infection and treatment not seen in the general population. HCV infection poses additional challenges and considerations for the management of cancer, and vice versa. HCV infection also can lead to the development of cancer, particularly hepa...

journal_title：World journal of gastroenterology

authors： Borchardt RA,Torres HA

更新日期：2014-03-21 00:00:00