Spiral CT in gastric carcinoma: comparison with barium study, fiberoptic gastroscopy and histopathology.

abstract：AIM:To investigate the effects of osteopontin (OPN) gene expression knockdown on colon cancer Lovo cells in vitro. METHODS:Four candidate small interfering RNA (siRNA) constructs targeting the OPN gene and a scrambled control sequence (NC-siRNA) were synthesized and inserted into a pGPU6/GFP/Neo expression vector. Aft...

journal_title：World journal of gastroenterology

authors： Wu XL,Lin KJ,Bai AP,Wang WX,Meng XK,Su XL,Hou MX,Dong PD,Zhang JJ,Wang ZY,Shi L

更新日期：2014-08-14 00:00:00

abstract：AIM:To investigate the effect and mechanism of action of the nitric oxide synthase (NOS) inhibitor NG-nitro-L-arginine methyl ester (L-NAME) on invasion and metastasis of human colorectal cancer cell line SL-174T. METHODS:Human colorectal cancer cell line SL-174T was cultured and treated separately with four different...

journal_title：World journal of gastroenterology

authors： Yu LB,Dong XS,Sun WZ,Zhao DL,Yang Y

更新日期：2005-10-28 00:00:00

abstract：AIM:To evaluate the accuracy of two non-invasive tests in a population of Alaska Native persons. High rates of Helicobacter pylori (H. pylori) infection, H. pylori treatment failure, and gastric cancer in this population necessitate documentation of infection status at multiple time points over a patient's life. METHO...

journal_title：World journal of gastroenterology

authors： Bruden DL,Bruce MG,Miernyk KM,Morris J,Hurlburt D,Hennessy TW,Peters H,Sacco F,Parkinson AJ,McMahon BJ

更新日期：2011-11-14 00:00:00

abstract：AIM:To investigate whether Dihydromyricetin (DHM) inhibits cell proliferation and promotes apoptosis by downregulating Notch1 expression. METHODS:The correlation between Notch1 and Hes1 (a Notch1 target molecule) expression in hepatoma samples was confirmed by qRT-PCR. In addition, MTT assays, flow cytometry and TUNEL...

journal_title：World journal of gastroenterology

authors： Lu CJ,He YF,Yuan WZ,Xiang LJ,Zhang J,Liang YR,Duan J,He YH,Li MY

更新日期：2017-09-14 00:00:00

abstract：AIM:To analyze the role of rs12979860 and rs8099917 polymorphisms in hepatitis C virus (HCV) genotype 1 infection of Brazilians. METHODS:A total of 145 adult patients diagnosed with genotype 1 chronic hepatitis C (CHC) who had completed a 48-wk regimen of pegylated-interferon α-2a or -2b plus ribavirin combination the...

journal_title：World journal of gastroenterology

authors： Garcia RF,Moreira S,de Araújo Ramos AL,Ferreira LE,de Mattos AA,Tovo CV,Nader LA,Ramos JA,Rondinelli E,de Jesus Dominici A,Garcia CE,de Souza Leite Pinho M,Brandão-Mello CE,Villela-Nogueira CA,de França PH

更新日期：2013-11-14 00:00:00

abstract：AIM:To investigate the pattern of mucin expression and concentration in bile obtained during endoscopic retrograde cholangiography (ERC) in relation to gallstone disease. METHODS:Bile samples obtained at ERC from 29 consecutive patients, 17 with and 12 without gallstone disease were evaluated for mucin content by gel ...

journal_title：World journal of gastroenterology

authors： Vilkin A,Geller A,Levi Z,Niv Y

更新日期：2009-05-21 00:00:00

abstract：:Rescue antiviral treatment for patients with resistance to preexisting nucleos(t)ide analogues remains a clinical challenge. The correct choice of a first-line treatment of high potency and with a high genetic barrier to achieve sustained long-term suppression of viral replication provides the best chance of preventin...

journal_title：World journal of gastroenterology

authors： Bang KB,Kim HJ

更新日期：2014-09-07 00:00:00

abstract：:Direct acting antivirals (DAAs) have revolutionized the treatment of hepatitis C virus (HCV) infection, achieving high rates (≥ 95%) of sustained virological response, with a good safety profile and high compliance rates. Consequently, it had been expected that viral clearance will reduce morbidity and mortality rates...

journal_title：World journal of gastroenterology

authors： Muzica CM,Stanciu C,Huiban L,Singeap AM,Sfarti C,Zenovia S,Cojocariu C,Trifan A

更新日期：2020-11-21 00:00:00

abstract：AIM:To achieve a better understanding of the pathogenesis of new type gosling viral enteritis virus (NGVEV) and the relationship between NGVEV and host cells. METHODS:The apoptosis of duck embryo fibroblasts (DEF) induced by NGVEV was investigated by fluorescence-activated cell sorter (FACS) and fluorescence microscop...

journal_title：World journal of gastroenterology

authors： Chen S,Cheng AC,Wang MS,Peng X

更新日期：2008-04-14 00:00:00

abstract：:The occurrence of pancreatic pleural effusion, secondary to an internal pancreatic fistula, is a rare clinical syndrome and diagnosis is often missed. The key to the diagnosis is a dramatically elevated pleural fluid amylase. This pancreatic pleural effusion is also called a pancreatic pleural fistula. It is character...

journal_title：World journal of gastroenterology

authors： Jin SG,Chen ZY,Yan LN,Zeng Y

更新日期：2010-09-21 00:00:00

abstract：AIM:To assess NY-ESO-1 expression in a cohort of esophageal adenocarcinomas. METHODS:A retrospective search of our tissue archive for esophageal resection specimens containing esophageal adenocarcinoma was performed, for cases which had previously been reported for diagnostic purposes, using the systematised nomenclat...

journal_title：World journal of gastroenterology

authors： Hayes SJ,Hng KN,Clark P,Thistlethwaite F,Hawkins RE,Ang Y

更新日期：2014-04-14 00:00:00

abstract：BACKGROUND:Acute liver failure (ALF) is a significant and complex hepatic insult that may rapidly progress to life-threatening conditions. Recently, menstrual blood stem cells (MenSCs) have been identified as a group of easily accessible mesenchymal stem cells with the advantages of non-invasive acquisition, low immuno...

journal_title：World journal of gastroenterology

authors： Cen PP,Fan LX,Wang J,Chen JJ,Li LJ

更新日期：2019-11-07 00:00:00

abstract：AIM:To investigate the role of Delta-like ligand 4 (DLL4) on tumour growth in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) in vivo. METHODS:We suppressed DLL4 expression in an HBV expressing HCC cell line, HepG2.2.15 and analysed the growth ability of cells as subcutaneous tumours in nude mice. Th...

journal_title：World journal of gastroenterology

authors： Kunanopparat A,Issara-Amphorn J,Leelahavanichkul A,Sanpavat A,Patumraj S,Tangkijvanich P,Palaga T,Hirankarn N

更新日期：2018-09-14 00:00:00

abstract：AIM:To investigate serum mean platelet volume (MPV) levels in acute pancreatitis (AP) patients and assess whether MPV effectively predicts the disease severity of AP. METHODS:We included 117 consecutive patients with AP as the AP group and 34 consecutive patients with colorectal polyps (before endoscopic treatment) as...

journal_title：World journal of gastroenterology

authors： Lei JJ,Zhou L,Liu Q,Xiong C,Xu CF

更新日期：2017-04-07 00:00:00

abstract：AIM:To assess quantitatively the relationship between fish intake and the incidence of gastrointestinal cancers in a meta-analysis of cohort studies. METHODS:We searched MEDLINE, Embase, Science Citation Index Expanded, and the bibliographies of retrieved articles. Prospective cohort studies were included if they repo...

journal_title：World journal of gastroenterology

authors： Yu XF,Zou J,Dong J

更新日期：2014-11-07 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is one of the major causes for cancer death worldwide. Treatment of metastatic disease remains challenging as only certain patients benefit from advances made with the intensified chemotherapy regimen folinic acid, irinotecan and oxaliplatin, the epidermal growth factor receptor ...

journal_title：World journal of gastroenterology

authors： Kruger S,Haas M,Ormanns S,Bächmann S,Siveke JT,Kirchner T,Heinemann V,Boeck S

更新日期：2014-08-21 00:00:00

abstract：AIM:To investigate the relationship between urinary peptide changes and Helicobacter pylori (H. pylori) infection using urinary peptidome profiling. METHODS:The study was performed in volunteers (n=137) who gave informed consent. Urinary peptides were enriched by magnetic beads based weak cation exchange chromatograph...

journal_title：World journal of gastroenterology

authors： Xiao D,Meng FL,He LH,Gu YX,Zhang JZ

更新日期：2011-02-07 00:00:00

abstract：AIM:Eph receptors and ephrin ligands play a pivotal role in development and tissue maintenance. Since previous data have indicated an involvement of ephrin-B2 in epithelial healing, we investigated the gene expression and downstream signaling pathways induced by ephrin-B mediated cell-cell signaling in intestinal epith...

journal_title：World journal of gastroenterology

authors： Hafner C,Meyer S,Hagen I,Becker B,Roesch A,Landthaler M,Vogt T

更新日期：2005-08-07 00:00:00

abstract：AIM:To evaluate the impact of hepatitis C virus (HCV) infection with genotype 1 or 3 and the presence or absence of liver cirrhosis (LC) in the early viral kinetics response to treatment. METHODS:Naive patients (n = 46) treated with interferon-alpha (IFN-alpha) and ribavirin and followed up with frequent early HCV-RNA...

journal_title：World journal of gastroenterology

authors： Medeiros-Filho JE,de Carvalho Mello IM,Pinho JR,Neumann AU,de Mello Malta F,da Silva LC,Carrilho FJ

更新日期：2006-12-07 00:00:00

abstract：:Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (OGCs) is very rare, less than 1% of all pancreatic malignancies, and shows worse prognosis than that of invasive ductal adenocarcinoma of the pancreas. We present a case of en bloc resection for a huge undifferentiated carcinoma with OGCs tha...

journal_title：World journal of gastroenterology

authors： Jo S

更新日期：2014-03-14 00:00:00

abstract：:Two-dimensional shear wave elastography (2D-SWE) is a rapid, simple and novel noninvasive method that has been proposed for assessing hepatic fibrosis in patients with chronic liver diseases (CLDs) based on measurements of liver stiffness. 2D-SWE can be performed easily at the bedside or in an outpatient clinic and yi...

journal_title：World journal of gastroenterology

authors： Xie LT,Yan CH,Zhao QY,He MN,Jiang TA

更新日期：2018-03-07 00:00:00

abstract：:Crohn's disease is a chronic inflammatory granulomatous process that usually involves different sites in the intestinal tract. Genetic and environmental factors are thought to play a role in its etiology and pathogenesis. The disorder has a heterogeneous clinical expression and data from tertiary care settings have do...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2009-03-21 00:00:00

abstract：AIM:To prospectively present our initial experience with totally laparoscopic transhiatal esophagogastrectomies for benign diseases of the cardia and distal esophagus. METHODS:Laparoscopic gastric mobilization and tubularization combined with transhiatal esophageal dissection and intrathoracic esophagogastric anastomo...

journal_title：World journal of gastroenterology

authors： Dulucq JL,Wintringer P,Mahajna A

更新日期：2007-01-14 00:00:00

abstract：:Microsomal glutathione transferase (MGST1, EC 2.5.1.18) is a membrane bound glutathione transferase extensively studied for its ability to detoxify reactive intermediates, including metabolic electrophile intermediates and lipophilic hydroperoxides through its glutathione dependent transferase and peroxidase activitie...

journal_title：World journal of gastroenterology

authors： Schaffert CS

更新日期：2011-05-28 00:00:00

abstract：AIM:To investigate the microRNA expression profile in esophageal neosquamous epithelium from patients who had undergone ablation of Barrett's esophagus. METHODS:High throughput screening using TaqMan® Array Human MicroRNA quantitative PCR was used to determine expression levels of 754 microRNAs in distal esophageal mu...

journal_title：World journal of gastroenterology

authors： Sreedharan L,Mayne GC,Watson DI,Bright T,Lord RV,Ansar A,Wang T,Kist J,Astill DS,Hussey DJ

更新日期：2017-08-14 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. NAFLD includes a wide spectrum of liver conditions ranging from simple steatosis to nonalcoholic steatohepatitis and advanced hepatic fibrosis. NAFLD has been recognized as a hepatic manifestation of metabolic syndrome linked w...

journal_title：World journal of gastroenterology

authors： Fotbolcu H,Zorlu E

更新日期：2016-04-28 00:00:00

abstract：BACKGROUND:The introduction of biologics has revolutionized the management of the chronic inflammatory bowel disease, ulcerative colitis (UC), with many patients experiencing significant improvements not only in their symptoms but in other outcomes relevant to individuals and society as a whole. In Germany, there are n...

journal_title：World journal of gastroenterology

authors： Teich N,Grümmer H,Jörgensen E,Liceni T,Holtkamp-Endemann F,Fischer T,Hohenberger S

更新日期：2020-06-07 00:00:00

abstract：AIM:To study whether H pylori are associated with chronic cholecystitis. METHODS:The subjects were divided into three groups: H pylori-infected cholecystitis group, H pylori-negative cholecystitis group and control group. Pathologic changes of the gallbladder were observed by optic and electronic microscopes and the l...

journal_title：World journal of gastroenterology

authors： Chen DF,Hu L,Yi P,Liu WW,Fang DC,Cao H

更新日期：2007-02-21 00:00:00

abstract：AIM:To compare the performance of the Da-an real-time hepatitis B virus (HBV) DNA assay and Abbott RealTime HBV assay. METHODS:HBV DNA standards as well as a total of 180 clinical serum samples from patients with chronic hepatitis B were measured using the Abbott and Da-an real-time polymerase chain reaction (PCR) ass...

journal_title：World journal of gastroenterology

authors： Qiu N,Li R,Yu JG,Yang W,Zhang W,An Y,Li T,Liu XE,Zhuang H

更新日期：2014-09-07 00:00:00

abstract：AIM:To study the effects of cortactin on the tumor biology of SGC-7901 cells and identify the mechanism involved in the process. METHODS:Cell lines in which cortactin was stably overexpressed or knocked down as well as the respective control cell lines were established by standard molecular methods. The effects of cor...

journal_title：World journal of gastroenterology

authors： Wei J,Zhao ZX,Li Y,Zhou ZQ,You TG

更新日期：2014-03-28 00:00:00