H pylori are associated with chronic cholecystitis.

Abstract:

AIM:To study whether H pylori are associated with chronic cholecystitis. METHODS:The subjects were divided into three groups: H pylori-infected cholecystitis group, H pylori-negative cholecystitis group and control group. Pathologic changes of the gallbladder were observed by optic and electronic microscopes and the levels of interleukin-1, 6 and 8 (IL-1, 6 and 8) were detected by radioimmunoassay. RESULTS:Histological evidence of chronic cholecystitis including degeneration, necrosis, inflammatory cell infiltration, were found in the region where H pylori colonized. Levels of IL-1, 6 and 8 in gallbladder mucosa homogenates were significantly higher in H pylori-infected cholecystitis group than those in H pylori-negative cholecystitis group and control group. CONCLUSION:H pylori infection may be related to cholecystitis.

journal_name

World J Gastroenterol

authors

Chen DF,Hu L,Yi P,Liu WW,Fang DC,Cao H

doi

10.3748/wjg.v13.i7.1119

subject

Has Abstract

pub_date

2007-02-21 00:00:00

pages

1119-22

issue

7

eissn

1007-9327

issn

2219-2840

journal_volume

13

pub_type

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