Hepatitis C virus lymphotropism and peculiar immunological phenotype: effects on natural history and antiviral therapy.

abstract：AIM:To investigate the effect of antiviral therapy with nucleoside analogs in hepatitis B virus (HBV)-related cirrhosis and esophageal varices. METHODS:Eligible patients with HBV-related cirrhosis and esophageal varices who consulted two tertiary hospitals in Beijing, China, the Chinese Second Artillery General Hospit...

journal_title：World journal of gastroenterology

authors： Li CZ,Cheng LF,Li QS,Wang ZQ,Yan JH

更新日期：2013-10-28 00:00:00

abstract：AIM:To elucidate the relationship between apoptotic protease activating factor-1 (Apaf-1) gene and gastric cancer. METHODS:Thirty-five postoperative cancer and adjacent normal tissue samples were collected in the present study. Expression of the Apaf-1 gene in these samples was analyzed by semi-quantitative RT-PCR. Lo...

journal_title：World journal of gastroenterology

authors： Wang HL,Bai H,Li Y,Sun J,Wang XQ

更新日期：2007-10-14 00:00:00

abstract：AIM:To study all the aspects of drain management in pancreatic surgery. METHODS:We conducted a systematic review according to the PRISMA guidelines. We searched the Cochrane Central Registry of Controlled Trials, EMBASE, Web of Science, and PubMed (MEDLINE) for relevant articles on drain management in pancreatic surge...

journal_title：World journal of gastroenterology

authors： Čečka F,Loveček M,Jon B,Skalický P,Šubrt Z,Neoral Č,Ferko A

更新日期：2015-10-28 00:00:00

abstract：AIM:To study the condition and potentiality of human umbilical cord blood stem cells (HUCBSC) to differentiate into hepatocytes in vivo or in vitro. METHODS:In a cell culture study of human umbilical cord blood stem cell (HUCBSC) differentiation, human umbilical cord blood mononuclear cells (HUCBMNC) were separated by...

journal_title：World journal of gastroenterology

authors： Tang XP,Zhang M,Yang X,Chen LM,Zeng Y

更新日期：2006-07-07 00:00:00

abstract：AIM:To construct a noninvasive assessment model consisting of routine laboratory data to predict significant fibrosis and cirrhosis in patients with chronic hepatitis B (CHB). METHODS:A total of 137 consecutive patients with CHB who underwent percutaneous liver biopsy were retrospectively analyzed. These patients were...

journal_title：World journal of gastroenterology

authors： Zhang YX,Wu WJ,Zhang YZ,Feng YL,Zhou XX,Pan Q

更新日期：2008-12-14 00:00:00

abstract：:The Prague C and M Criteria have been developed for the objective endoscopic diagnosis of Barrett's esophagus (BE). BE arises between the squamocolumnar junction and the gastroesophageal junction at the proximal margin of the gastric folds. In this study, we reported that 43.0% of the subjects examined were diagnosed ...

journal_title：World journal of gastroenterology

authors： Akiyama T,Sekino Y,Iida H,Koyama S,Gotoh E,Maeda S,Nakajima A,Inamori M

更新日期：2012-07-14 00:00:00

abstract：:Tumors of the minor papilla of the duodenum are quite rare. We successfully and safely treated an 18-mm adenoma of the minor papilla associated with pancreas divisum using endoscopic papillectomy. A 64-year-old man was admitted to our hospital for treatment of an asymptomatic mass in the minor papilla detected by uppe...

journal_title：World journal of gastroenterology

authors： Kanamori A,Kumada T,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Toyoda H,Kawashima H,Itoh A,Hirooka Y,Goto H

更新日期：2009-03-07 00:00:00

abstract：:In 2018, the pan-Janus kinase (JAK) inhibitor tofacitinib was launched for the treatment of ulcerative colitis (UC). Although tofacitinib has proven efficacious in patients with active UC, it failed in patients with Crohn's disease (CD). This finding strongly hints at a different contribution of JAK signaling in both ...

journal_title：World journal of gastroenterology

authors： Cordes F,Foell D,Ding JN,Varga G,Bettenworth D

更新日期：2020-07-28 00:00:00

abstract：AIM:To investigate the association between adiponectin levels and risk of colorectal adenoma and cancer (early and advanced). METHODS:A cross-sectional study in a cohort of hospital-based patients was conducted between January 2004 and March 2006 at Yamagata University Hospital. Male subjects, who had colorectal tumor...

journal_title：World journal of gastroenterology

authors： Otake S,Takeda H,Fujishima S,Fukui T,Orii T,Sato T,Sasaki Y,Nishise S,Kawata S

更新日期：2010-03-14 00:00:00

abstract：:Patients with esophageal cancer often require esophagectomy with esophagogastrostomy. However, the incidence of complications, such as hemorrhage, during operations for esophageal cancer is high, even with minimally invasive surgery. Without the appropriate interventions, the risk of major intraoperative and postopera...

journal_title：World journal of gastroenterology

authors： Zhang GF,Chai Y,Li WS,Huang LS,Shen G

更新日期：2014-09-21 00:00:00

abstract：:An inefficient cellular immune response likely leads to chronic hepatitis C virus (HCV) infection. Resolution of chronic HCV infection in the absence of treatment is a rare occurrence. We report the case of a 39-year old white male with a 17-year history of chronic HCV infection, who eradicated HCV following a serious...

journal_title：World journal of gastroenterology

authors： Byrnes V,Chopra S,Koziel MJ

更新日期：2007-08-21 00:00:00

abstract：AIM:To define probiotic monotherapy effect on Helicobacter pylori (H. pylori) status by performing a systematic review. METHODS:Methods of analysis and inclusion criteria were based on PRISMA recommendations. Relevant publications were identified by searching PubMed, MEDLINE, Science Direct, and EMBASE. The end-point ...

journal_title：World journal of gastroenterology

authors： Losurdo G,Cubisino R,Barone M,Principi M,Leandro G,Ierardi E,Di Leo A

更新日期：2018-01-07 00:00:00

abstract：AIM:To explore the mode of inheritance of hepatocellular carcinoma (HCC) in a moderately high-incidence area of East China. METHODS:A pedigree survey was conducted in 210 families (3315 individuals) ascertained through 210 HCC probands in Haimen, Jiangsu Province. Simple segregation analysis was conducted using SEGRAN...

journal_title：World journal of gastroenterology

authors： Cai RL,Meng W,Lu HY,Lin WY,Jiang F,Shen FM

更新日期：2003-11-01 00:00:00

abstract：:Peritoneal carcinomatosis appears to be the most common pattern of metastasis or recurrence and is associated with poor prognosis in gastric cancer patients. Many efforts have been made to improve the survival in patients with peritoneal metastasis. Hyperthermic intraperitoneal chemotherapy remains a widely accepted s...

journal_title：World journal of gastroenterology

authors： Wei J,Wu ND,Liu BR

更新日期：2016-09-07 00:00:00

abstract：:The goal of therapy in chronic hepatitis C virus (HCV) infection is sustained virological response (SVR) which reflects HCV eradication. Treatment against HCV has dramatically improved with the recent availability of direct-acting antivirals (DAAs) including sofosbuvir, simeprevir, daclatasvir, ledipasvir/sofosbuvir, ...

journal_title：World journal of gastroenterology

authors： Cholongitas E,Pipili C,Papatheodoridis G

更新日期：2015-08-28 00:00:00

abstract：AIM:To investigate the utility of K-ras mutation analysis of ultrasound guided fine-needle aspirate biopsy of pancreatic masses. METHODS:Sixty-six ultrasound guided fine-needle biopsies were evaluated by cytology, histology and k-ras mutation. The mutation at codon 12 of the k-ras oncogene was detected by artificial r...

journal_title：World journal of gastroenterology

authors： Zheng M,Liu LX,Zhu AL,Qi SY,Jiang HC,Xiao ZY

更新日期：2003-01-01 00:00:00

abstract：AIM:To study the outcome of patients undergoing surgical resection of the bowel for sustained radiation-induced damage intractable to conservative management. METHODS:During a 7-year period we operated on 17 cases (5 male, 12 female) admitted to our surgical department with intestinal radiation injury (IRI). They were...

journal_title：World journal of gastroenterology

authors： Perrakis N,Athanassiou E,Vamvakopoulou D,Kyriazi M,Kappos H,Vamvakopoulos NC,Nomikos I

更新日期：2011-09-21 00:00:00

abstract：AIM:To evaluate the accuracy of two non-invasive tests in a population of Alaska Native persons. High rates of Helicobacter pylori (H. pylori) infection, H. pylori treatment failure, and gastric cancer in this population necessitate documentation of infection status at multiple time points over a patient's life. METHO...

journal_title：World journal of gastroenterology

authors： Bruden DL,Bruce MG,Miernyk KM,Morris J,Hurlburt D,Hennessy TW,Peters H,Sacco F,Parkinson AJ,McMahon BJ

更新日期：2011-11-14 00:00:00

abstract：AIM:To clarify the strategy for early diagnosis of pancreaticobiliary maljunction (PBM) without biliary dilatation and to pathologically examine gallbladder before cancer develops. METHODS:The anatomy of the union of the pancreatic and bile ducts was assessed by using endoscopic retrograde cholangiopancreatography (ER...

journal_title：World journal of gastroenterology

authors： Takuma K,Kamisawa T,Tabata T,Hara S,Kuruma S,Inaba Y,Kurata M,Honda G,Tsuruta K,Horiguchi S,Igarashi Y

更新日期：2012-07-14 00:00:00

abstract：AIM:To assess the outcomes of drug therapy (DT) followed by pancreatic endotherapy for continuing painful episodes in recurrent acute pancreatitis. METHODS:DT comprised of pancreatic enzymes and anti-oxidants failing which, endotherapy (ET; pancreatic sphincterotomy and stent placement) was done. The frequency of pain...

journal_title：World journal of gastroenterology

authors： Pai CG,Kamath MG,Shetty MV,Kurien A

更新日期：2017-05-21 00:00:00

abstract：AIM:To examine the expression of pancreatic duodenal homeobox-1 (PDX-1) transcription factor in human colorectal cancer. METHODS:RT-PCR, Western blotting, and immuno-histochemistry were performed to determine the expression pattern of transcription factor PDX-1 in primary colorectal tumor, hepatic metastasis, and beni...

journal_title：World journal of gastroenterology

authors： Ballian N,Liu SH,Brunicardi FC

更新日期：2008-10-14 00:00:00

abstract：AIM:To investigate functional change of dendritic cells (DCs) derived from allogeneic partial liver graft undergoing acute rejection in rats. METHODS:Allogeneic (SD rat to LEW rat) whole and 50 % partial liver transplantation were performed. DCs from liver grafts 0 hr and 4 days after transplantation were isolated and...

journal_title：World journal of gastroenterology

authors： Xu MQ,Yao ZX

更新日期：2003-01-01 00:00:00

abstract：:The liver is the commonest site of distant metastasis of colorectal cancer and nearly half of the patients with colorectal cancer ultimately develop liver involved during the course of their diseases. Surgery is the only therapy that offers the possibility of cure for patients with hepatic metastatic diseases. Five-ye...

journal_title：World journal of gastroenterology

authors： Liu LX,Zhang WH,Jiang HC

更新日期：2003-02-01 00:00:00

abstract：AIM:To identify factors related to serious postoperative bacterial and fungal infections in the first 3 mo after living donor liver transplantation (LDLT). METHODS:In the present study, the data of 207 patients from 2004 to 2011 were reviewed. The pre-, intra- and post-operative factors were statistically analyzed. Al...

journal_title：World journal of gastroenterology

authors： Li C,Wen TF,Mi K,Wang C,Yan LN,Li B

更新日期：2012-04-28 00:00:00

abstract：:The advances of laparoscopic surgery since the early 1990s have caused one of the largest technical revolutions in medicine since the detection of antibiotics (1922, Flemming), the discovery of DNA structure (1953, Watson and Crick), and solid organ transplantation (1954, Murray). Perseverance through a rocky start an...

journal_title：World journal of gastroenterology

authors： Kaiser AM

更新日期：2014-11-07 00:00:00

abstract：:Studies on rodents and humans demonstrate an inherited predisposition to hepatocellular carcinoma (HCC). Analysis of the molecular alterations involved in the acquisition of a phenotype resistant or susceptible to hepatocarcinogenesis showed a deregulation of G1 and S phases in HCC of genetically susceptible F344 rats...

journal_title：World journal of gastroenterology

authors： Feo F,Frau M,Pascale RM

更新日期：2008-11-21 00:00:00

abstract：:The coexistence of hepatocellular carcinoma (HCC) and non-Hodgkin's lymphoma (NHL) in the liver is rare. Reports show that these patients have cirrhotic livers or hepatitis virus infections before they develop HCC and NHL. We present a patient with hepatitis B virus infection who was transferred to our hospital with a...

journal_title：World journal of gastroenterology

authors： Lee MH,Lin YC,Cheng HT,Chuang WY,Huang HC,Kao HW

更新日期：2015-12-07 00:00:00

abstract：AIM:To investigate the prognostic significance of S100A4 expression in colorectal cancer and its correlation with expression of E-cadherin and p53. METHODS:A cohort of archival formalin-fixed paraffin-embedded specimens was selected from 127 patients with colorectal cancer who underwent surgical resection between Apri...

journal_title：World journal of gastroenterology

authors： Kwak JM,Lee HJ,Kim SH,Kim HK,Mok YJ,Park YT,Choi JS,Moon HY

更新日期：2010-08-21 00:00:00

abstract：AIM:To sum up the clinical characteristics of patients with central pontine myelinolysis (CPM) after orthotopic liver transplantation (OLT) and to document the possible causes of CPM. METHODS:Data of 142 patients undergoing OLT between January 1999 to May 2003 were analyzed retrospectively. Following risk factors duri...

journal_title：World journal of gastroenterology

authors： Yu J,Zheng SS,Liang TB,Shen Y,Wang WL,Ke QH

更新日期：2004-09-01 00:00:00

abstract：AIM:To investigate the hotspots, direction, and the time course of evolution of hepatitis A virus in the process of consecutive cell culture passage in human KMB17 diploid cells. METHODS:Wild type hepatitis A virus H2w was serially propagated in KMB17 cells until passage 30, and the full-length genomes of H2w and its ...

journal_title：World journal of gastroenterology

authors： Tang CH,Mao JS,Chai SA,Chen Y,Zhuang FC

更新日期：2007-09-14 00:00:00