Coexistence of hepatoma with mantle cell lymphoma in a hepatitis B carrier.

Abstract:

:The coexistence of hepatocellular carcinoma (HCC) and non-Hodgkin's lymphoma (NHL) in the liver is rare. Reports show that these patients have cirrhotic livers or hepatitis virus infections before they develop HCC and NHL. We present a patient with hepatitis B virus infection who was transferred to our hospital with a newly detected liver mass; abdominal computed tomography examination showed one hypodense mass of 7 cm in diameter and multiple mesenteric and mediastinal lymph nodes. A liver tumor biopsy showed a hepatoma, and the pathologic findings from an inguinal lymph node excision showed mantle cell lymphoma. An immunohistochemical stain confirmed that the atypical lymphoid cells within the HCC were positive for the CD20, CD5 and cyclin D1 antigens. Taking these findings into account, the hepatic tumor was determined to be a HCC infiltrated by mantle cell lymphoma.

journal_name

World J Gastroenterol

authors

Lee MH,Lin YC,Cheng HT,Chuang WY,Huang HC,Kao HW

doi

10.3748/wjg.v21.i45.12981

subject

Has Abstract

pub_date

2015-12-07 00:00:00

pages

12981-6

issue

45

eissn

1007-9327

issn

2219-2840

journal_volume

21

pub_type

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