Changes in the esophageal mucosa of patients with non erosive reflux disease: How far have we gone?

abstract：:Dysphagia lusoria is a term used to describe dysphagia secondary to vascular compression of the oesophagus. The various embryologic anomalies of the arterial brachial arch system often remain unrecognised and asymptomatic, but in 30%-40% of cases can result in tracheo-oesophageal symptoms, which in the majority of cas...

journal_title：World journal of gastroenterology

authors： Bennett AL,Cock C,Heddle R,Morcom RK

更新日期：2013-04-21 00:00:00

abstract：:The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), may be complicated by colorectal cancer (CRC). In a recent population-based cohort study of 47 347 Danish patients with IBD by Tine Jess and colleagues 268 patients with UC and 70 patients with CD developed CRC during 30 years of ...

journal_title：World journal of gastroenterology

authors： Andersen V,Halfvarson J,Vogel U

更新日期：2012-08-21 00:00:00

abstract：AIM:To investigate the microRNA expression profile in esophageal neosquamous epithelium from patients who had undergone ablation of Barrett's esophagus. METHODS:High throughput screening using TaqMan® Array Human MicroRNA quantitative PCR was used to determine expression levels of 754 microRNAs in distal esophageal mu...

journal_title：World journal of gastroenterology

authors： Sreedharan L,Mayne GC,Watson DI,Bright T,Lord RV,Ansar A,Wang T,Kist J,Astill DS,Hussey DJ

更新日期：2017-08-14 00:00:00

abstract：:Helicobacter pylori (H. pylori) is the most common infection in humans, with a marked disparity between developed and developing countries. Although H. pylori infections are asymptomatic in most infected individuals, they are intimately related to malignant gastric conditions such as gastric cancer and gastric mucosa-...

journal_title：World journal of gastroenterology

authors： Campuzano-Maya G

更新日期：2014-09-28 00:00:00

abstract：:Colorectal cancer (CRC) is one of the commonest cancers with 1.2 million new cases diagnosed each year in the world. It remains the fourth most common cause of cancer-related mortality in the world and accounts for > 600000 cancer-related deaths each year. There have been significant advances in treatment of metastati...

journal_title：World journal of gastroenterology

authors： Khan K,Wale A,Brown G,Chau I

更新日期：2014-09-21 00:00:00

abstract：AIM:To explore recent trends, modes of diagnosis, ethnic distribution and the mortality to incidence ratio of primary liver cancer by subtypes in England and Wales. METHODS:We obtained incidence (1979-2008) and mortality (1968-2008) data for primary liver cancer for England and Wales and calculated age-standardised in...

journal_title：World journal of gastroenterology

authors： Ladep NG,Khan SA,Crossey MM,Thillainayagam AV,Taylor-Robinson SD,Toledano MB

更新日期：2014-02-14 00:00:00

abstract：AIM:To investigate the diagnostic accuracy of acoustic radiation force impulse (ARFI) imaging as a noninvasive method for the assessment of liver fibrosis in chronic hepatitis C (CHC) patients. METHODS:We performed a prospective blind comparison of ARFI elastography, APRI index and FibroMax in a consecutive series of ...

journal_title：World journal of gastroenterology

authors： Fierbinteanu-Braticevici C,Andronescu D,Usvat R,Cretoiu D,Baicus C,Marinoschi G

更新日期：2009-11-28 00:00:00

abstract：:A 65-year-old woman was found to have dilatation of the intrahepatic bile duct in the right anterior segment during a general health. Laboratory data were within normal ranges and no solid mass was detected in her abdominal computer tomography (CT) or nuclear magnetic resonance imaging (MRI). However, endoscopic retro...

journal_title：World journal of gastroenterology

authors： Hayashi J,Matsuoka S,Inami M,Ohshiro S,Ishigami A,Fujikawa H,Miyagawa M,Mimatsu K,Kuboi Y,Kanou H,Oida T,Moriyama M

更新日期：2008-03-14 00:00:00

abstract：:Colorectal cancer remains the third most common cancer in both women and men worldwide. Identifying modifiable dietary factors is crucial in developing primary prevention strategies. Vitamin B6 is involved in more than 100 coenzyme reactions, and may influence colorectal cancer risk in multiple ways including through ...

journal_title：World journal of gastroenterology

authors： Zhang XH,Ma J,Smith-Warner SA,Lee JE,Giovannucci E

更新日期：2013-02-21 00:00:00

abstract：:The small intestine is approximately 5-6 m long and occupies a large area in the abdominal cavity. These factors preclude the use of ordinary endoscopy and X-ray to thoroughly examine the small intestine for bleeding of vascular malformations. Thus, the diagnosis of intestinal bleeding is very difficult. A 47-year-old...

journal_title：World journal of gastroenterology

authors： Cui J,Huang LY,Lin SJ,Yi LZ,Wu CR,Zhang B

更新日期：2014-10-14 00:00:00

abstract：AIM:To investigate the prevalence of hepatitis G virus (HGV) infection and to analyse the homology of different HGV strains in Southern China. METHODS:A total of 1993 sera from different groups in Guangdong, Hong Kong, and Yunnan were detected by reverse transcription polymerase chain reaction (RT-PCR). The nucleotide...

journal_title：World journal of gastroenterology

authors： Li G,Ma HH,Lau GK,Leung YK,Yao CL,Chong YT,Tang WH,Yao JL

更新日期：2002-12-01 00:00:00

abstract：AIM:To investigate the efficacy of exercise interventions on hepatic fat mobilization in non-alcoholic fatty liver disease (NAFLD) patients. METHODS:Ovid-Medline, PubMed, EMBASE and Cochrane database were searched for randomized trials and prospective cohort studies in adults aged ≥ 18 which investigated the effects o...

journal_title：World journal of gastroenterology

authors： Golabi P,Locklear CT,Austin P,Afdhal S,Byrns M,Gerber L,Younossi ZM

更新日期：2016-07-21 00:00:00

abstract：AIM:To evaluate retrospectively the correlation between enhancement patterns on dynamic computed tomography (CT) and angiogenesis and fibrosis in pancreatic adenocarcinoma. METHODS:Twenty-three patients with pancreatic adenocarcinoma underwent dynamic CT and tumor resection. In addition to the absolute and relative en...

journal_title：World journal of gastroenterology

authors： Hattori Y,Gabata T,Matsui O,Mochizuki K,Kitagawa H,Kayahara M,Ohta T,Nakanuma Y

更新日期：2009-07-07 00:00:00

abstract：:The diagnosis of early gastric cancer (EGC) is of great interest because its endoscopic and surgical treatment presents the best chance for a cure. With technical development, endoscopic submucosal dissection (ESD) has been widely performed for the curative treatment of EGC in Korea. Multinational studies of ESD for E...

journal_title：World journal of gastroenterology

authors： Cho WY,Cho JY,Chung IK,Kim JI,Jang JS,Kim JH

更新日期：2011-06-07 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the second most common cause of cancer death worldwide. It is broadly described that cyclooxygenase-2 (COX-2) is mainly overexpressed in CRC but less is known regarding post-translational modifications of this enzyme that may regulate its activity, intracellular localization and st...

journal_title：World journal of gastroenterology

authors： Prieto P,Jaén RI,Calle D,Gómez-Serrano M,Núñez E,Fernández-Velasco M,Martín-Sanz P,Alonso S,Vázquez J,Cerdán S,Peinado MÁ,Boscá L

更新日期：2019-01-28 00:00:00

abstract：AIM:To investigate the expression of hypoxia-inducible factor (HIF)-2alpha/endothelial PAS domain protein1 (EPAS1) in hepatocellular carcinoma (HCC). METHODS:Expression of HIF-2alpha/EPAS1 was investigated immunohistochemically on paraffin-embedded sections from 97 patients with HCC. To further confirm that HIF-2alpha...

journal_title：World journal of gastroenterology

authors： Bangoura G,Yang LY,Huang GW,Wang W

更新日期：2004-02-15 00:00:00

abstract：:Long-term outcome data in pancreatic adenocarcinoma are predominantly based on surgical series, as resection is currently considered essential for long-term survival. In contrast, five-year survival in non-resected patients has rarely been reported. In this report, we examined the incidence and natural history of ≥ 5-...

journal_title：World journal of gastroenterology

authors： Oh SY,Edwards A,Mandelson MT,Lin B,Dorer R,Helton WS,Kozarek RA,Picozzi VJ

更新日期：2015-12-28 00:00:00

abstract：:Foreign body ingestion is a common complaint in gastrointestinal clinics. It is usually not difficult to diagnose because most of the patients report a definitive history of accidental foreign body ingestion. However, in rare cases, patients do not have a clear history. Thus, the actual condition of the patient is dif...

journal_title：World journal of gastroenterology

authors： Lu YP,Yao M,Zhou XY,Huang B,Qi WB,Chen ZH,Xu LS

更新日期：2014-10-21 00:00:00

abstract：AIM:To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS:Production of recombinant sH2a and development of a monoclonal antibody and an enzyme-linked immunosorbent assay (ELISA). This assay was used to determine the presence and concentrati...

journal_title：World journal of gastroenterology

authors： Benyair R,Kondratyev M,Veselkin E,Tolchinsky S,Shenkman M,Lurie Y,Lederkremer GZ

更新日期：2011-12-28 00:00:00

abstract：AIM:We have previously demonstrated that cholangiocytes, the epithelial cells lining intrahepatic bile ducts, encode two functional bile acid transporters via alternative splicing of a single gene to facilitate bile acid vectorial transport. Cholangiocytes possess ASBT, an apical sodium-dependent bile acid transporter ...

journal_title：World journal of gastroenterology

authors： Kip NS,Lazaridis KN,Masyuk AI,Splinter PL,Huebert RC,LaRusso NF

更新日期：2004-05-15 00:00:00

abstract：AIM:To identify key variables associated with colon cancer testing using the 2009 California Health Inventory Survey (CHIS). METHODS:The CHIS has been conducted biennially since 2001 using a two-stage, geographically stratified random-digit-dial sample design to produce a representative sample of the entire State. For...

journal_title：World journal of gastroenterology

authors： Modiri A,Makipour K,Gomez J,Friedenberg F

更新日期：2013-02-28 00:00:00

abstract：:Of the diverse biological agents used for patients with ulcerative colitis, the anti-tumor necrosis factor-α agents infliximab and adalimumab have been used in large-scale clinical trials and are currently widely used in the treatment of inflammatory bowel disease patients. Recent studies have indicated that golimumab...

journal_title：World journal of gastroenterology

authors： Seo GS,Chae SC

更新日期：2014-10-07 00:00:00

abstract：AIM:To demonstrate the possible associations between genetic polymorphisms of aldehyde dehydrogenase-2 (ALDH2) and esophageal squamous cell dysplasia (ESCD). METHODS:All participants came from an area of high incidence of esophageal cancer and underwent an endoscopic staining examination; biopsies were taken from a no...

journal_title：World journal of gastroenterology

authors： Zhou YZ,Diao YT,Li H,Li HQ,Ma Q,Cui J

更新日期：2010-07-21 00:00:00

abstract：AIM:To investigate the effect of Lactobacillus-containing commercially available probiotic formulations in Germany during antibiotic treatment with an analysis of cost-efficiency. METHODS:In an observational study, we analyzed the frequency of bowel movements from 258 patients with infections in a primary care hospita...

journal_title：World journal of gastroenterology

authors： Dietrich CG,Kottmann T,Alavi M

更新日期：2014-11-14 00:00:00

abstract：AIM:To prepare the human hepatocellular carcinoma-(HCC)-targeted liposome microbubbles and to investigate their immunological properties. METHODS:Human hepatocarcinoma specific monoclonal antibody HAb18 was attached to the surface of home-made liposome microbubbles by static attraction to prepare the targeted liposome...

journal_title：World journal of gastroenterology

authors： Bian AN,Gao YH,Tan KB,Liu P,Zeng GJ,Zhang X,Liu Z

更新日期：2004-12-01 00:00:00

abstract：AIM:To investigate the anti-hepatofibrotic effects of Gardenia jasminoides in liver fibrosis. METHODS:Male Sprague-Dawley rats underwent common bile duct ligation (BDL) for 14 d and were treated with Gardenia jasminoides by gavage. The effects of Gardenia jasminoides on liver fibrosis and the detailed molecular mechan...

journal_title：World journal of gastroenterology

authors： Chen YH,Lan T,Li J,Qiu CH,Wu T,Gou HJ,Lu MQ

更新日期：2012-12-28 00:00:00

abstract：:Autoimmune hepatitis (AIH) is an unresolving progressive liver disease of unknown etiology characterized by hypergammaglobulinemia, autoantibodies detection and interface hepatitis. Due to the absence of specific diagnostic markers and the large heterogeneity of its clinical, laboratory and histological features, AIH ...

journal_title：World journal of gastroenterology

authors： Gatselis NK,Zachou K,Koukoulis GK,Dalekos GN

更新日期：2015-01-07 00:00:00

abstract：:The chronic inflammatory process underlying inflammatory bowel disease (IBD), comprising Crohn's disease and ulcerative colitis, derives from the interplay of several components in a genetically susceptible host. These components include environmental elements and gut microbiota a dysbiosis. For decades, immune abnorm...

journal_title：World journal of gastroenterology

authors： Nanini HF,Bernardazzi C,Castro F,de Souza HSP

更新日期：2018-11-07 00:00:00

abstract：AIM:To compare two tests for exocrine pancreatic function (EPF) for use in M-ANNHEIM staging for pancreatitis. METHODS:One hundred and ninety four consecutive patients with acute pancreatitis (AP; n = 13), recurrent acute pancreatitis (RAP; n = 65) and chronic pancreatitis (CP; n = 116) were enrolled. EPF was assessed...

journal_title：World journal of gastroenterology

authors： Kamath MG,Pai CG,Kamath A,Kurien A

更新日期：2017-03-28 00:00:00

abstract：:Transplantation cannot be considered the most important therapeutic procedure for hepatocellular carcinoma (HCC). In France, no more than 2% of patients with HCC undergo a transplantation. Randomized controlled trial must assess the benefit to risk ratio of various potentially "curative" treatment procedures (transpla...

journal_title：World journal of gastroenterology

authors： Braillon A

更新日期：2009-11-14 00:00:00