Gardenia jasminoides attenuates hepatocellular injury and fibrosis in bile duct-ligated rats and human hepatic stellate cells.

abstract：:Homocysteine is an amino acid generated metabolically by the S-adenosylmethionine-dependent transmethylation pathway. In addition to being a well-known independent risk factor for coronary heart disease, is also a risk factor for cancer. Patients suffering from inflammatory bowel diseases (IBD) including ulcerative co...

journal_title：World journal of gastroenterology

authors： Keshteli AH,Baracos VE,Madsen KL

更新日期：2015-01-28 00:00:00

abstract：AIM:To assess the safety of bismuth used in Helicobacter pylori (H pylori) eradication therapy regimens. METHODS:We conducted a systematic review and meta-analysis. MEDLINE and EMBASE were searched (up to October 2007) to identify randomised controlled trials comparing bismuth with placebo or no treatment, or bismuth ...

journal_title：World journal of gastroenterology

authors： Ford AC,Malfertheiner P,Giguere M,Santana J,Khan M,Moayyedi P

更新日期：2008-12-28 00:00:00

abstract：:We report a case of hepatocellular carcinoma (HCC) occurring in a patient with Crohn's disease (CD) without chronic hepatitis or liver cirrhosis, and review the clinicopathological features of HCC in CD patients. A 37-year-old Japanese man with an 8-year history of CD and a medication history of azathioprine underwent...

journal_title：World journal of gastroenterology

authors： Ishida M,Naka S,Shiomi H,Tsujikawa T,Andoh A,Nakahara T,Saito Y,Kurumi Y,Takikita-Suzuki M,Kojima F,Hotta M,Tani T,Fujiyama Y,Okabe H

更新日期：2010-07-07 00:00:00

abstract：AIM:To analyze the association of tobacco smoking polymorphism of CYP1A1 (7th exon) and GSTM1 genotype and esophageal cancer(EC) in Xi'an. METHODS:A hospital based case-control study, with molecular epidemiological method, was carried out. Polymorphism of CYP1A1 and GSTM1 of samples from 127 EC cases and 101 controls ...

journal_title：World journal of gastroenterology

authors： Wang AH,Sun CS,Li LS,Huang JY,Chen QS

更新日期：2002-02-01 00:00:00

abstract：:Transient thrombocytopenia is a common phenomenon after liver transplantation. After liver transplantation (LT), platelet count decreases and reaches a nadir on postoperative days 3-5, with an average reduction in platelet counts of 60%; platelet count recovers to preoperative levels approximately two weeks after LT. ...

journal_title：World journal of gastroenterology

authors： Takahashi K,Nagai S,Safwan M,Liang C,Ohkohchi N

更新日期：2018-04-07 00:00:00

abstract：AIM:To examine the effect of Fusobacterium nucleatum (F. nucleatum) on the microenvironment of colonic neoplasms and the expression of inflammatory mediators and microRNAs (miRNAs). METHODS:Levels of F. nucleatum DNA, cytokine gene mRNA (TLR2, TLR4, NFKB1, TNF, IL1B, IL6 and IL8), and potentially interacting miRNAs (m...

journal_title：World journal of gastroenterology

authors： Proença MA,Biselli JM,Succi M,Severino FE,Berardinelli GN,Caetano A,Reis RM,Hughes DJ,Silva AE

更新日期：2018-12-21 00:00:00

abstract：BACKGROUND:Although previous studies have confirmed the feasibility of magnetic compression anastomosis (MCA), there is still a risk of long-term anastomotic stenosis. For traditional MCA devices, a large device is associated with great pressure, and eventually increased leakage. AIM:To develop a novel MCA device to s...

journal_title：World journal of gastroenterology

authors： Chen H,Ma T,Wang Y,Zhu HY,Feng Z,Wu RQ,Lv Y,Dong DH

更新日期：2020-11-14 00:00:00

abstract：:Gluten-sensitive enteropathy, also known as coeliac disease (CD), is an autoimmune disorder occurring in genetically susceptible individuals that damages the small intestine and interferes with the absorption of other nutrients. As it is triggered by dietary gluten and related prolamins present in wheat, rye and barle...

journal_title：World journal of gastroenterology

authors： Sziksz E,Pap D,Veres G,Fekete A,Tulassay T,Vannay Á

更新日期：2014-06-07 00:00:00

abstract：AIM:To evaluate the clinical outcomes and prognostic factors after intravenous corticosteroids following oral corticosteroid failure in active ulcerative colitis patients. METHODS:Consecutive patients with moderate to severe ulcerative colitis who had been treated with a course of intravenous corticosteroids after ora...

journal_title：World journal of gastroenterology

authors： Jeon HH,Lee HJ,Jang HW,Yoon JY,Jung YS,Park SJ,Hong SP,Kim TI,Kim WH,Cheon JH

更新日期：2013-01-14 00:00:00

abstract：:Autoimmune hepatitis (AIH) is a rare chronic inflammatory disease of the liver, which affects a group of patients who lost their immunological tolerance to antigens of the liver. It is clinically characterized by hypergammaglobulinemia, elevated liver enzymes, presence of autoantibodies and histological changes. Altho...

journal_title：World journal of gastroenterology

authors： Ferri Liu PM,de Miranda DM,Fagundes ED,Ferreira AR,Simões e Silva AC

更新日期：2013-07-28 00:00:00

abstract：AIM:To explore the role and mechanism of total flavone of Abelmoschus manihot (TFA) on epithelial-mesenchymal transition (EMT) progress of Crohn's disease (CD) intestinal fibrosis. METHODS:First, CCK-8 assay was performed to assess TFA on the viability of intestinal epithelial (IEC-6) cells and select the optimal conc...

journal_title：World journal of gastroenterology

authors： Yang BL,Zhu P,Li YR,Xu MM,Wang H,Qiao LC,Xu HX,Chen HJ

更新日期：2018-08-14 00:00:00

abstract：:The etiology of inflammatory bowel disease (IBD) has not yet been clarified and immunosuppressive agents which non-specifically reduce inflammation and immunity have been used in the conventional therapies for IBD. Evidence indicates that a dysregulation of mucosal immunity in the gut of IBD causes an overproduction o...

journal_title：World journal of gastroenterology

authors： Nakamura K,Honda K,Mizutani T,Akiho H,Harada N

更新日期：2006-08-07 00:00:00

abstract：BACKGROUND:Identifying predictors of therapeutic response is the cornerstone of personalized medicine. AIM:To identify predictors of long-term mucosal healing (MH) in patients with Crohn's disease (CD) treated with tumor necrosis factor α (TNF-α) inhibitors. METHODS:Prospective single center study. Consecutive patien...

journal_title：World journal of gastroenterology

authors： Alfaro I,Masamunt MC,Planell N,López-García A,Castro J,Gallego M,Barastegui R,Giner A,Vara A,Salas A,Ricart E,Panés J,Ordás I

更新日期：2019-04-14 00:00:00

abstract：AIM:To investigate the effect of fermented soy milk on human ecosystem in the intestinal tract by way of examining the population of different microorganisms isolated from fecal samples. METHODS:A crossover experimental design was applied. Twenty-eight healthy adults completed this experiment. Each subject consumed 25...

journal_title：World journal of gastroenterology

authors： Cheng IC,Shang HF,Lin TF,Wang TH,Lin HS,Lin SH

更新日期：2005-02-28 00:00:00

abstract：AIM:To analyze the safety and efficiency of direct-acting antiviral (DAA) regimens in liver-transplanted patients with hepatitis C virus (HCV) reinfection. METHODS:Between January 2014 and December 2016, 39 patients with HCV reinfection after liver transplantation were treated at our tertiary referral center with sofo...

journal_title：World journal of gastroenterology

authors： Rupp C,Hippchen T,Neuberger M,Sauer P,Pfeiffenberger J,Stremmel W,Gotthardt DN,Mehrabi A,Weiss KH

更新日期：2018-03-28 00:00:00

abstract：AIM:To investigate the prevalence and characteristics of uninvestigated dyspepsia among college students in Zhejiang Province. METHODS:Young adult students attending undergraduate (within the 4-year program) and graduate (only first-year students) colleges in Zhejiang Province were recruited between November 2010 and ...

journal_title：World journal of gastroenterology

authors： Li M,Lu B,Chu L,Zhou H,Chen MY

更新日期：2014-04-07 00:00:00

abstract：AIM:To investigate in patients with functional dyspepsia (FD) after an every-day meal whether (1) gastrointestinal (GI) and extra-GI symptoms had any relation with the degree of antral volume, (2) the onset of postprandial symptoms was associated with, and may predict, delayed gastric emptying. METHODS:In 94 symptomat...

journal_title：World journal of gastroenterology

authors： Pallotta N,Pezzotti P,Corazziari E

更新日期：2006-11-21 00:00:00

abstract：AIM:To identify risk factors to help predict which patients are likely to fail to appear for an endoscopic procedure. METHODS:This was a retrospective, chart review, cohort study in a Canadian, tertiary care, academic, hospital-based endoscopy clinic. Patients included were: those undergoing esophagogastroduodenoscopy...

journal_title：World journal of gastroenterology

authors： Wong VK,Zhang HB,Enns R

更新日期：2009-06-21 00:00:00

abstract：AIM:To investigate the association of nuclear morphometry and DNA content with resectability of pancreatic cancer. METHODS:A total of 36 patients with pancreatic adenocarcinoma were divided into resectable group and unresectable group. The nuclear morphometry and DNA contents of tumor cells were analyzed by IBAS autoi...

journal_title：World journal of gastroenterology

authors： He YC,Peng W,Qiao JG,Cao J,Chen JW

更新日期：2003-08-01 00:00:00

abstract：:In colon cancer, classic disease staging remains the key prognosis and treatment determinant. Although adjuvant chemotherapy has an established role in stage III colon cancer patients, in stage II it is still a subject of controversy due to its restriction to a small subgroup of patients with high-risk histopathologic...

journal_title：World journal of gastroenterology

authors： Saridaki Z,Souglakos J,Georgoulias V

更新日期：2014-06-14 00:00:00

abstract：AIM:To evaluate the efficacy and safety of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) with undifferentiated-type histology. METHODS:A systematic literature review was conducted using the core databases. Complete resection, curative resection, en bloc resection, recurrence and adverse event r...

journal_title：World journal of gastroenterology

authors： Bang CS,Baik GH,Shin IS,Kim JB,Suk KT,Yoon JH,Kim YS,Kim DJ,Shin WG,Kim KH,Kim HY,Lim H,Kang HS,Kim JH,Kim JB,Jung SW,Kae SH,Jang HJ,Choi MH

更新日期：2015-05-21 00:00:00

abstract：AIM:To check the efficacy of the PERFACT procedure in highly complex fistula-in-ano. METHODS:The PERFACT procedure (proximal superficial cauterization, emptying regularly fistula tracts and curettage of tracts) entails two steps: superficial cauterization of mucosa at and around the internal opening and keeping all th...

journal_title：World journal of gastroenterology

authors： Garg P,Garg M

更新日期：2015-04-07 00:00:00

abstract：AIM:To investigate and evaluate the technical feasibility and clinical effectiveness of fluoroscopically guided peroral uncovered expandable metal stent placement to treat gastric outlet and duodenal obstructions. METHODS:Fifteen consecutive patients underwent peroral placement of Wallstent(TM) Enteral Endoprosthesis ...

journal_title：World journal of gastroenterology

authors： Huang Q,Dai DK,Qian XJ,Zhai RY

更新日期：2007-10-28 00:00:00

abstract：AIM:To investigate anti-apoptotic effects of glycyrrhizic acid (GA) against fibrosis in carbon tetrachloride (CCl4)-induced liver injury and its contributing factors. METHODS:Liver fibrosis was induced by administration of CCl4 for 8 wk. Pathological changes in the liver of rats were examined by hematoxylin-eosin stai...

journal_title：World journal of gastroenterology

authors： Liang B,Guo XL,Jin J,Ma YC,Feng ZQ

更新日期：2015-05-07 00:00:00

abstract：AIM:To examine the association between parity and gastric cancer (the cases are almost all premenopausal women) risk in a cohort of young parous women. METHODS:The study cohort consisted of all women with a record of a first and singleton childbirth in the Birth Register between 1978 and 1987. We tracked each woman fr...

journal_title：World journal of gastroenterology

authors： Chang CC,Chen CC,Chiu HF,Yang CY

更新日期：2011-02-14 00:00:00

abstract：AIM:To evaluate, whether humoral hepatitis-B-vaccine non-responders also fail to mount a T cell response and to compare these results to normal vaccinees. METHODS:Fourty-seven health care employees were enrolled in this study including all available non-responders (n = 13) with an anti-HBsAg titer < 10 kU/L and all av...

journal_title：World journal of gastroenterology

authors： Weihrauch MR,von Bergwelt-Baildon M,Kandic M,Weskott M,Klamp W,Rosler J,Schultze JL

更新日期：2008-04-28 00:00:00

abstract：:Ulcerative colitis (UC) is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum. The hallmark clinical symptom of UC is bloody diarrhea. The clinical course is marked by exacerbations and remissions, which may occur spontaneously or in response to treatment changes or intercurr...

journal_title：World journal of gastroenterology

authors： da Silva BC,Lyra AC,Rocha R,Santana GO

更新日期：2014-07-28 00:00:00

abstract：:Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (OGCs) is very rare, less than 1% of all pancreatic malignancies, and shows worse prognosis than that of invasive ductal adenocarcinoma of the pancreas. We present a case of en bloc resection for a huge undifferentiated carcinoma with OGCs tha...

journal_title：World journal of gastroenterology

authors： Jo S

更新日期：2014-03-14 00:00:00

abstract：BACKGROUND:Small-for-size grafts (SFSGs) in living donor liver transplantation (LDLT) could optimize donor postoperative outcomes and also expand the potential donor pool. Evidence on whether SFSGs would affect medium-term and long-term recipient graft survival is lacking. AIM:To evaluate the impact of small-for-size ...

journal_title：World journal of gastroenterology

authors： Ma KW,Wong KHC,Chan ACY,Cheung TT,Dai WC,Fung JYY,She WH,Lo CM,Chok KSH

更新日期：2019-09-28 00:00:00

abstract：AIM:To determine the expression of c-fos in gastric myenteric plexus and spinal cord of rats with cervical spondylosis and its clinical significance. METHODS:A cervical spondylosis model was established in rats by destroying the stability of cervical posterior column, and the cord segments C(4-6) and gastric antrum we...

journal_title：World journal of gastroenterology

authors： Song PS,Kong KM,Niu CY,Qi WL,Wu LF,Wang XJ,Han W,Huang K,Chen ZF

更新日期：2005-01-28 00:00:00