Glycyrrhizic acid inhibits apoptosis and fibrosis in carbon-tetrachloride-induced rat liver injury.

abstract：:AIM:To study the relationship between insulin A chain regions and insulin biological activities, we designed a series of insulin analogues with changes at A21, A12-18 of C terminal helical region and A8-10 located in the region of A6-A11 intra-chain disulphide bond.METHODS:Insulin A-chain analogues were prepared by st...

journal_title：World journal of gastroenterology

authors： Yang SZ,Huang YD,Jie XF,Feng YM,Niu JY

更新日期：2000-06-01 00:00:00

abstract：:The gut-brain axis is a bidirectional information interaction system between the central nervous system (CNS) and the gastrointestinal tract, in which gut microbiota plays a key role. The gut microbiota forms a complex network with the enteric nervous system, the autonomic nervous system, and the neuroendocrine and ne...

journal_title：World journal of gastroenterology

authors： Ding JH,Jin Z,Yang XX,Lou J,Shan WX,Hu YX,Du Q,Liao QS,Xie R,Xu JY

更新日期：2020-10-28 00:00:00

abstract：AIM:To systematically review the data on distinctive aspects of peptic ulcer disease (PUD), Dieulafoy's lesion (DL), and Mallory-Weiss syndrome (MWS) in patients with advanced alcoholic liver disease (aALD), including alcoholic hepatitis or alcoholic cirrhosis. METHODS:Computerized literature search performed via PubM...

journal_title：World journal of gastroenterology

authors： Nojkov B,Cappell MS

更新日期：2016-01-07 00:00:00

abstract：AIM:To understand CD133 promoter hypermethylation and expression in 32 colorectal cancer cell lines. METHODS:Nucleic acid was isolated from 32 colorectal cancer cell lines and CD133 expression levels were measured by reverse transcription-polymerase chain reaction (RT-PCR) and real-time PCR. Promoter methylation statu...

journal_title：World journal of gastroenterology

authors： Jeon YK,Kim SH,Choi SH,Kim KH,Yoo BC,Ku JL,Park JG

更新日期：2010-07-07 00:00:00

abstract：:Bone metastases from gastric cancer (GC) are considered a relatively uncommon finding; however, they are related to poorer prognosis. Both primary GC and its metastatic progression rely on angiogenesis. Several lines of evidence from GC patients strongly support the involvement of mast cells (MCs) positive to tryptase...

journal_title：World journal of gastroenterology

authors： Leporini C,Ammendola M,Marech I,Sammarco G,Sacco R,Gadaleta CD,Oakley C,Russo E,De Sarro G,Ranieri G

更新日期：2015-10-07 00:00:00

abstract：AIM:To evaluate the effect of gastrectomy on diabetes mellitus (DM) and hypertension (HTN) in non-obese gastric cancer patients. METHODS:A total of 100000 patients, diagnosed with either type 2 DM or HTN, were randomly selected from the 2004 Korean National Health Insurance System claims. Among them, 360 diabetes and ...

journal_title：World journal of gastroenterology

authors： Lee EK,Kim SY,Lee YJ,Kwak MH,Kim HJ,Choi IJ,Cho SJ,Kim YW,Lee JY,Kim CG,Yoon HM,Eom BW,Kong SY,Yoo MK,Park JH,Ryu KW

更新日期：2015-01-28 00:00:00

abstract：:Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and HLA-DQ8 haplotypes, and enteropathy. Vaccination is the most poten...

journal_title：World journal of gastroenterology

authors： Anania C,Olivero F,Spagnolo A,Chiesa C,Pacifico L

更新日期：2017-05-14 00:00:00

abstract：:Intrahepatic clear cell cholangiocarcinoma is very rare - only 8 cases have been reported. A 56-year-old Japanese man with chronic hepatitis B infection was diagnosed with a 2.2 cm hepatocellular carcinoma on imaging, and hepatic segmentectomy was performed. Histopathologically, the tumor cells had copious clear cytop...

journal_title：World journal of gastroenterology

authors： Toriyama E,Nanashima A,Hayashi H,Abe K,Kinoshita N,Yuge S,Nagayasu T,Uetani M,Hayashi T

更新日期：2010-05-28 00:00:00

abstract：:Although plasma cell infiltration is not rare in autopsy of patients with multiple myeloma (MM), it is very rarely detected in living patients. This is because MM rarely causes significant liver dysfunction that requires further evaluation. A 49-year-old man presented with acute renal failure and was diagnosed with ka...

journal_title：World journal of gastroenterology

authors： Rahhal FE,Schade RR,Nayak A,Coleman TA

更新日期：2009-04-28 00:00:00

abstract：:Peritoneal dissemination represents a devastating form of gastric cancer (GC) progression with a dismal prognosis. There is no effective therapy for this condition. The 5-year survival rate of patients with peritoneal dissemination is 2%, even including patients with only microscopic free cancer cells without macrosco...

journal_title：World journal of gastroenterology

authors： Kanda M,Kodera Y

更新日期：2016-08-14 00:00:00

abstract：AIM:To examine an increased risk of esophageal adenocarcinoma is restricted to patients who develop Barrett's esophagus or whether esophagitis per se is a risk factor for adenocarcinoma. METHODS:A population-based cohort of patients with histological evidence of esophagitis without Barrett's esophagus was constructed ...

journal_title：World journal of gastroenterology

authors： Murphy SJ,Anderson LA,Johnston BT,Fitzpatrick DA,Watson PR,Monaghan P,Murray LJ

更新日期：2005-12-14 00:00:00

abstract：:Colonic perforation during endoscopic diagnostic or therapeutic procedures, represents an uncommon occurrence even if, together with haemorrhage, it is still the most common complication of colonoscopy, with an incidence ranging between 0.1% and 2% of all colonoscopic procedures. The ideal treatment in these cases rem...

journal_title：World journal of gastroenterology

authors： Barbagallo F,Castello G,Latteri S,Grasso E,Gagliardo S,La Greca G,Di Blasi M

更新日期：2007-05-28 00:00:00

abstract：:Hepatitis C virus (HCV) affects 130-210 million people worldwide and is one of the major risk factors for hepatocellular carcinoma. Globally, at least one third of hepatocellular carcinoma cases are attributed to HCV infection, and 350000 people died from HCV related diseases per year. There is a great geographical va...

journal_title：World journal of gastroenterology

authors： Lee MH,Yang HI,Yuan Y,L'Italien G,Chen CJ

更新日期：2014-07-28 00:00:00

abstract：:Nestin is a class VI intermediate filament protein that was originally described as a neuronal stem cell marker during central nervous system (CNS) development, and is currently widely used in that capacity. Nestin is also expressed in non-neuronal immature or progenitor cells in normal tissues. Under pathological con...

journal_title：World journal of gastroenterology

authors： Ishiwata T,Matsuda Y,Naito Z

更新日期：2011-01-28 00:00:00

abstract：AIM:To investigate the inhibitory effect and possible mechanism of action of schisandrin B in SC-B on gastric cancer cells in vitro. METHODS:SC-B consisted of schisandrin B, aloe-emodin, and Astragalus polysaccharides. Exponentially growing human gastric cancer SGC-7901 cells were divided into six treatment groups: (1...

journal_title：World journal of gastroenterology

authors： Liu XN,Zhang CY,Jin XD,Li YZ,Zheng XZ,Li L

更新日期：2007-12-28 00:00:00

abstract：:Management of acute diarrhea remains a global challenge, particularly in resource-limiting countries. Oral rehydration solution (ORS), a passive rehydrating therapy developed approximately 40 years ago, remains the mainstay treatment. Although ORS is effective for hydration, since it does not inhibit enterotoxin-media...

journal_title：World journal of gastroenterology

authors： Cheng SX

更新日期：2016-03-07 00:00:00

abstract：:The optimal method for monitoring quiescent disease in patients with Crohn's disease (CD) and ulcerative colitis is yet to be determined. Endoscopic evaluation with ileocolonoscopy is the gold standard but is invasive, costly, and time-consuming. There are many commercially available biomarkers that may be used in cli...

journal_title：World journal of gastroenterology

authors： Chang S,Malter L,Hudesman D

更新日期：2015-10-28 00:00:00

abstract：:There have been multiple NOD2/CARD15 genotype-phenotype analyses undertaken in patients with Crohn's disease since the gene's discovery in 2001. This review focuses on the major published series based upon their size and on the presence of specific clinical and genetic information provided in the published material fr...

journal_title：World journal of gastroenterology

authors： Radford-Smith G,Pandeya N

更新日期：2006-11-28 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the 10 most common cancers worldwide. There is no ideal treatment for HCC yet and many researchers are trying to improve the effects of treatment by changing therapeutic strategies. As the majority of human cancers seem to exhibit either abnormal p53 gene or disrupted p53 gene ...

journal_title：World journal of gastroenterology

authors： Guan YS,La Z,Yang L,He Q,Li P

更新日期：2007-02-21 00:00:00

abstract：:An 85 year male patient complaining epigastric discomfort was admitted. From the esophagogastroduodenoscopy, three early gastric cancer (EGCa) lesions had been identified and these were diagnosed as adenocarcinoma with poorly differentiated cell type. The patient underwent operation. From the post-operative mapping, h...

journal_title：World journal of gastroenterology

authors： Seong H,Kim JI,Lee HJ,Kim HJ,Cho HJ,Kim HK,Cheung DY,Kim DJ,Kim W,Kim TJ

更新日期：2013-11-28 00:00:00

abstract：:A rare case of multiple small bowel ruptures due to ischemic enteritis (ISE) is reported. The patient was admitted to the hospital with acute abdominal pain followed by bloody diarrhoeas. Preoperative colonoscopic findings were similar to those presented in Crohn's disease. Intraoperatively, ischemic lesions and multi...

journal_title：World journal of gastroenterology

authors： Delikoukos S,Christodoulidis G,Zacharoulis D,Poultsidi A,Hatzitheofilou C

更新日期：2006-07-14 00:00:00

abstract：:Dysphagia lusoria is a term used to describe dysphagia secondary to vascular compression of the oesophagus. The various embryologic anomalies of the arterial brachial arch system often remain unrecognised and asymptomatic, but in 30%-40% of cases can result in tracheo-oesophageal symptoms, which in the majority of cas...

journal_title：World journal of gastroenterology

authors： Bennett AL,Cock C,Heddle R,Morcom RK

更新日期：2013-04-21 00:00:00

abstract：AIM:Primary biliary cirrhosis (PBC) is a chronic, cholestatic disease of autoimmune etiology, the histology of which shows a destruction of the intrahepatic bile duct and portal inflammation. Ursodeoxycholic acid (UDCA) is now used as a first-line drug for asymptomatic PBC (aPBC) because it is reported that UDCA decrea...

journal_title：World journal of gastroenterology

authors： Dohmen K,Mizuta T,Nakamuta M,Shimohashi N,Ishibashi H,Yamamoto K

更新日期：2004-03-15 00:00:00

abstract：:The overall survival for patients with advanced hepatocellular carcinoma (HCC) is still limited. Although the multi-kinase inhibitor sorafenib has recently been approved for this disease, response rates are still low and patients often face dose-limiting toxicities which lead to a reduction in prognosis and treatment ...

journal_title：World journal of gastroenterology

authors： Wich C,Agaimy A,Strobel D,Wissniowski TT,Hartmann A,Ocker M

更新日期：2010-07-28 00:00:00

abstract：:Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas (UCOGCP) is an unusual pancreatic neoplasm that represents < 1% of all pancreatic malignancies. Moreover, the giant cells of UCOGCP morphologically resemble the benign giant cells of bone tumors. Due to the rarity of this tumor type, the histo...

journal_title：World journal of gastroenterology

authors： Gao HQ,Yang YM,Zhuang Y,Liu P

更新日期：2015-01-14 00:00:00

abstract：AIM:To determine if liver stiffness (LS) measurements by means of transient elastography (TE) correlate with the presence of significant esophageal varices (EV) and if they can predict the occurrence of variceal bleeding. METHODS:We studied 1000 cases of liver cirrhosis divided into 2 groups: patients without EV or wi...

journal_title：World journal of gastroenterology

authors： Sporea I,Raţiu I,Sirli R,Popescu A,Bota S

更新日期：2011-05-07 00:00:00

abstract：:Ulcerative colitis (UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Azulfidine, Asacol, Pentasa, Dipe...

journal_title：World journal of gastroenterology

authors： Xu CT,Meng SY,Pan BR

更新日期：2004-08-15 00:00:00

abstract：AIM:We aimed to observe the expression of extracellular matrix (ECM) and cellular adhesion molecules (CAM) in cirrhotic liver tissues after hepatitis C virus (HCV) infection. METHODS:Twelve patients with post HCV inflammatory liver cirrhosis were selected to evaluate their liver function and other virological, patholo...

journal_title：World journal of gastroenterology

authors： Xu X,Li YM,Ji H,Hou CZ,Cheng YB,Ma FP

更新日期：2005-04-14 00:00:00

abstract：AIM:To investigate the frequency of serum IgA-antiendomysial antibody positivity in patients with low bone mineral density and to assess the risk group for screening of celiac disease. METHODS:One hundred and thirty-five patients (14 male, 121 female) with idiopathic low bone mineral density were evaluated. The median...

journal_title：World journal of gastroenterology

authors： Karakan T,Ozyemisci-Taskiran O,Gunendi Z,Atalay F,Tuncer C

更新日期：2007-06-07 00:00:00

abstract：AIM:To investigate the utility of K-ras mutation analysis of ultrasound guided fine-needle aspirate biopsy of pancreatic masses. METHODS:Sixty-six ultrasound guided fine-needle biopsies were evaluated by cytology, histology and k-ras mutation. The mutation at codon 12 of the k-ras oncogene was detected by artificial r...

journal_title：World journal of gastroenterology

authors： Zheng M,Liu LX,Zhu AL,Qi SY,Jiang HC,Xiao ZY

更新日期：2003-01-01 00:00:00