Associations between NOD2/CARD15 genotype and phenotype in Crohn's disease--Are we there yet?

abstract：:The treatment of alcoholic hepatitis remains one of the most debated topics in medicine and a field of continued research. In this review, we discuss the evolution of scoring systems, including the recent development of the Glasgow alcoholic hepatitis score, role of liver biopsy and current treatment interventions. St...

journal_title：World journal of gastroenterology

authors： Rongey C,Kaplowitz N

更新日期：2006-11-21 00:00:00

abstract：:A 57-year-old man consulted a local hospital because of a persistent slight fever. At the age of 37 years he was diagnosed having B-type hepatitis, but left the liver dysfunction untreated. Twenty years later, he was diagnosed having chronic hepatitis B, hepatocellular carcinoma (HCC) and macrocytic anemia, and referr...

journal_title：World journal of gastroenterology

authors： Okada T,Kubota K,Kita J,Kato M,Sawada T

更新日期：2007-08-28 00:00:00

abstract：:The use of thiopurines as immunosuppression for the treatment of refractory or chronic active inflammatory bowel disease is established for both Crohn's disease and ulcerative colitis. Nevertheless, many questions remain concerning the optimal treatment regimens of azathioprine, 6-mercaptopurine and thioguanine. We wi...

journal_title：World journal of gastroenterology

authors： Frei P,Biedermann L,Nielsen OH,Rogler G

更新日期：2013-02-21 00:00:00

abstract：AIM:To evaluate the effects of ginger on gastric motility and emptying, abdominal symptoms, and hormones that influence motility in dyspepsia. METHODS:Eleven patients with functional dyspepsia were studied twice in a randomized double-blind manner. After an 8-h fast, the patients ingested three capsules that contained...

journal_title：World journal of gastroenterology

authors： Hu ML,Rayner CK,Wu KL,Chuah SK,Tai WC,Chou YP,Chiu YC,Chiu KW,Hu TH

更新日期：2011-01-07 00:00:00

abstract：:Celiac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and HLA-DQ8 haplotypes, and enteropathy. Vaccination is the most poten...

journal_title：World journal of gastroenterology

authors： Anania C,Olivero F,Spagnolo A,Chiesa C,Pacifico L

更新日期：2017-05-14 00:00:00

abstract：BACKGROUND:Acute liver failure (ALF) is a significant and complex hepatic insult that may rapidly progress to life-threatening conditions. Recently, menstrual blood stem cells (MenSCs) have been identified as a group of easily accessible mesenchymal stem cells with the advantages of non-invasive acquisition, low immuno...

journal_title：World journal of gastroenterology

authors： Cen PP,Fan LX,Wang J,Chen JJ,Li LJ

更新日期：2019-11-07 00:00:00

abstract：AIM:To identify new diagnostic markers and drug targets, the gene expression profiles of pancreatic cancer were compared with that of adjacent normal tissues utilizing cDNA microarray analysis. METHODS:cDNA probes were prepared by labeling mRNA from samples of six pancreatic carcinoma tissues with Cy5-dUTP and mRNA fr...

journal_title：World journal of gastroenterology

authors： Tan ZJ,Hu XG,Cao GS,Tang Y

更新日期：2003-04-01 00:00:00

abstract：AIM:To investigate whether common variants in the oxidative pathway genes influence inflammatory bowel disease (IBD) risk among Moroccan patients. METHODS:The distribution of (TAAA)n_rs12720460 and (CCTTT)n _rs3833912 NOS2A microsatellite repeats, HIF-1A_rs11549467 and NFKB1-94ins/delATTG_rs28362491 was analyzed in 50...

journal_title：World journal of gastroenterology

authors： Senhaji N,Nadifi S,Zaid Y,Serrano A,Rodriguez DAL,Serbati N,Karkouri M,Badre W,Martín J

更新日期：2017-12-21 00:00:00

abstract：AIM:To examine the accuracy of the aspartate aminotransferase (AST)/Platelet Ratio Index (APRI) and FIB-4, in predicting longitudinal changes in liver histology in hepatitis C virus (HCV) patients. METHODS:Patients that underwent repeat liver biopsies at least 1 year apart from 1999 to 2007 were identified. Liver fibr...

journal_title：World journal of gastroenterology

authors： Mummadi RR,Petersen JR,Xiao SY,Snyder N

更新日期：2010-12-07 00:00:00

abstract：:Perfusion of individual tissues is a basic physiological process that is necessary to sustain oxygenation and nutrition at a cellular level. Ischemia, or the insufficiency of perfusion, is a common mechanism for tissue death or degeneration, and at a lower threshold, a mechanism for the generation of sensory signallin...

journal_title：World journal of gastroenterology

authors： Hoff DA,Gregersen H,Hatlebakk JG

更新日期：2009-01-14 00:00:00

abstract：AIM:To investigate whether mesenchymal stem cells (MSCs) from adipose-derived stromal cells (ADSCs) and bone marrow stromal cells (BMSCs) have similar hepatic differentiation potential. METHODS:Mouse ADSCs and BMSCs were isolated and cultured. Their morphological and phenotypic characteristics, as well as their multip...

journal_title：World journal of gastroenterology

authors： Xu LJ,Wang SF,Wang DQ,Ma LJ,Chen Z,Chen QQ,Wang J,Yan L

更新日期：2017-10-14 00:00:00

abstract：AIM:To determine the pattern and distribution of colonic diverticulosis in Thai adults. METHODS:A review of the computerized radiology database for double contrast barium enema (DCBE) in Thai adults was performed at the Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. Incomplete studies and...

journal_title：World journal of gastroenterology

authors： Lohsiriwat V,Suthikeeree W

更新日期：2013-12-14 00:00:00

abstract：:Previously, we reported the efficacy of a newly developed inverted overtube in shortening the hemostatic time and obtaining a clear endoscopic view in emergency endoscopic hemostasis. This device also helped us to perform gastric endoscopic submucosal dissection (ESD) more safely by changing the direction of gravity i...

journal_title：World journal of gastroenterology

authors： Mori H,Rafiq K,Kobara H,Nishiyama N,Fujihara S,Yachida T,Ayagi M,Tani J,Miyoshi H,Masaki T

更新日期：2014-02-14 00:00:00

abstract：AIM:To investigate the role of insulin-like growth factor binding protein-7 (IGFBP-7) in the activation and transdifferentiation of hepatic stellate cells (HSC) in vitro. METHODS:Rat HSC-T6 cells were cultured in separate dishes and treated with various concentration of transforming growth factor (TGF)-beta(1), IGFBP-...

journal_title：World journal of gastroenterology

authors： Liu LX,Huang S,Zhang QQ,Liu Y,Zhang DM,Guo XH,Han DW

更新日期：2009-07-14 00:00:00

abstract：AIM:To analyze the available evidence about the risk of extrapancreatic malignancies and pancreatic ductal adenocarcinoma associated to pancreatic intraductal papillary mucinous tumors (IPMNs). METHODS:A systematic search of literature was undertaken using MEDLINE, EMBASE, Cochrane and Web-of-Science libraries. No lim...

journal_title：World journal of gastroenterology

authors： Baiocchi GL,Molfino S,Frittoli B,Pigozzi G,Gheza F,Gaverini G,Tarasconi A,Ricci C,Bertagna F,Grazioli L,Tiberio GA,Portolani N

更新日期：2015-06-21 00:00:00

abstract：AIM:To investigate the possible involvement of 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase [1alpha-25(OH) (2) D(3)] in butyrate-induced differentiation in human intestinal cell line Caco-2 cells. METHODS:Caco-2 cells were incubated either with 3 mmol/L butyrate and 1 micromol/L 25(OH) (2) D(3) or with 1 micromol/L 1al...

journal_title：World journal of gastroenterology

authors： Schröder O,Turak S,Daniel C,Gaschott T,Stein J

更新日期：2005-12-07 00:00:00

abstract：:Somatostatinomas are extremely rare neuroendocrine tumors of the gastrointestinal tract, first described in the pancreas in 1977 and in the duodenum in 1979. They may be functional and cause somatostatinoma or inhibitory syndrome, but more frequently are non-functioning pancreatic endocrine tumors that produce somatos...

journal_title：World journal of gastroenterology

authors： Colović RB,Matić SV,Micev MT,Grubor NM,Atkinson HD,Latincić SM

更新日期：2009-12-14 00:00:00

abstract：AIM:To review the cases reported in the literature, examined their clinicopathological features, and evaluated the efficacy of different therapeutic modalities for this rare condition. METHODS:A search of the MEDLINE database revealed 16 cases of pericarditis carcinomatosa (PC) originating from GC reported in the lite...

journal_title：World journal of gastroenterology

authors： Kobayashi M,Okabayashi T,Okamoto K,Namikawa T,Araki K

更新日期：2005-11-28 00:00:00

abstract：:Pneumatosis cystoides intestinalis (PCI) is a relatively rare condition characterized by intraluminal gas in the gastrointestinal tract. Several chemotherapeutic agents have been reported to be associated with PCI, although fluorouracil-related PCI is extremely rare. We report a case of a 76-year old man who received ...

journal_title：World journal of gastroenterology

authors： Mimatsu K,Oida T,Kawasaki A,Kano H,Kuboi Y,Aramaki O,Amano S

更新日期：2008-05-28 00:00:00

abstract：AIM:To compare the efficacy and safety of single daily amikacin vs. cefotaxime in the 5-d treatment of spontaneous bacterial peritonitis (SBP). METHODS:Thirty-seven cirrhotic patients with SBP, 19 in group A and 18 in group B, were studied. Group A received 1 g of cefotaxime every 6 h, and group B received 500 mg of a...

journal_title：World journal of gastroenterology

authors： Chen TA,Lo GH,Lai KH,Lin WJ

更新日期：2005-11-21 00:00:00

abstract：AIM:To determine the resistance patterns of Helicobacter pylori (H. pylori) strains isolated from patients in Beijing and monitor the change of antibiotic resistance over time. METHODS:In this prospective, serial and cross-sectional study, H. pylori cultures were successfully obtained from 371 and 950 patients (never ...

journal_title：World journal of gastroenterology

authors： Zhang YX,Zhou LY,Song ZQ,Zhang JZ,He LH,Ding Y

更新日期：2015-03-07 00:00:00

abstract：AIM:To construct pcDNA3.1-Egr.1p-p16 recombinant plasmid and investigate the expression of p16 in pancreatic cancer JF305 cells induced by radiation and the feasibility of gene radiotherapy for pancreatic carcinoma. METHODS:Human p16 cDNA was ligated to the downstream of Egr-1 promotor to construct pcDNA3.1-Egr.1p-p16...

journal_title：World journal of gastroenterology

authors： Ma HB,Wang XJ,Di ZL,Xia H,Li Z,Liu J,Ma J,Kang HF,Wu CM,Bai MH

更新日期：2007-08-21 00:00:00

abstract：AIM:To assess the efficacy and safety of combined directly acting antivirals (DAAs) for the treatment of Chinese chronic hepatitis C (CHC) patients in a real-world setting. METHODS:Hospitalized CHC patients who were treated with DAAs at Peking University First Hospital between January 2015 and December 2016 were enrol...

journal_title：World journal of gastroenterology

authors： Chen JH,Zeng Z,Zhang XX,Zhang Y,Zhang RW,Wang S,Wu CH,Yu M,Liu D,Xi HL,Zhou YX,An YY,Xu XY

更新日期：2017-06-14 00:00:00

abstract：AIM:To evaluate clinical outcomes of patients that underwent surgery, transarterial embolization (TAE), or supportive care for spontaneously ruptured hepatocellular carcinoma (HCC). METHODS:A consecutive 54 patients who diagnosed as spontaneously ruptured HCC at our institution between 2003 and 2012 were retrospective...

journal_title：World journal of gastroenterology

authors： Jin YJ,Lee JW,Park SW,Lee JI,Lee DH,Kim YS,Cho SG,Jeon YS,Lee KY,Ahn SI

更新日期：2013-07-28 00:00:00

abstract：AIM:To investigate the association between cytokine gene polymorphism and disease status in chronic hepatitis C genotype 3 by liver biopsy, ALT, HCV RNA levels and response to treatment. METHODS:Patients with chronic hepatitis C genotype 3 were analyzed for single nucleotide polymorphisms of interleukin (IL)-10, IL-1 ...

journal_title：World journal of gastroenterology

authors： Abbas Z,Moatter T,Hussainy A,Jafri W

更新日期：2005-11-14 00:00:00

abstract：AIM:To prospectively investigate the detection rate of laterally spreading tumors (LSTs) of the colorectum by computed tomography (CT) colonography (CTC). METHODS:Patients with LSTs measuring ≥ 20 mm detected during colonoscopy were prospectively enrolled in the study. All patients underwent colonoscopy and subsequent...

journal_title：World journal of gastroenterology

authors： Togashi K,Utano K,Kijima S,Sato Y,Horie H,Sunada K,Lefor AT,Sugimoto H,Yasuda Y

更新日期：2014-12-14 00:00:00

abstract：AIM:To investigate the allelic and haplotypic association of reg1alpha gene with tropical calcific pancreatitis (TCP). Since TCP is known to have a variable genetic basis, we investigated the interaction between mutations in the susceptibility genes, SPINK1 and CTSB with reg1alpha polymorphisms. METHODS:We analyzed th...

journal_title：World journal of gastroenterology

authors： Mahurkar S,Bhaskar S,Reddy DN,Rao GV,Chandak GR

更新日期：2007-11-28 00:00:00

abstract：:AIM:To further clarify the clinicopathological, immunohistochemical and electron microscopic features, and prognostic aspect of basaloid squamous carcinoma (BSC), a rare esophageal carcinoma.METHODS:We reviewed 763 documented cases of esophageal malignancies from year (1977-1996) from our hospital, and discovered 16 (...

journal_title：World journal of gastroenterology

authors： Zhang XH,Sun GQ,Zhou XJ,Guo HF,Zhang TH

更新日期：1998-10-01 00:00:00

abstract：:We experienced a case of intussusception caused by cys- tic lymphangioma of the colon in a 32 years old female who was admitted to our hospital for the chief complaint of bloody stool. In the colonoscopic examination, cystic mass with stalk which had smooth mucosal surface was noted at the descending colon. Abdominal ...

journal_title：World journal of gastroenterology

authors： Kim TO,Lee JH,Kim GH,Heo J,Kang DH,Song GA,Cho M

更新日期：2006-04-07 00:00:00

abstract：AIM:To investigate the relationship between the methylation status in the SLIT2 and TGFB2 promoters and colonic inflammation in inflammatory bowel disease patients. METHODS:We evaluated the methylation status of 2 genes (SLIT2 and TGFB2) in 226 biopsies taken from 62 colonoscopies of 38 patients (29 ulcerative colitis...

journal_title：World journal of gastroenterology

authors： Lobatón T,Azuara D,Rodríguez-Moranta F,Loayza C,Sanjuan X,de Oca J,Fernández-Robles A,Guardiola J,Capellá G

更新日期：2014-08-14 00:00:00