Abstract:
:Pneumatosis cystoides intestinalis (PCI) is a relatively rare condition characterized by intraluminal gas in the gastrointestinal tract. Several chemotherapeutic agents have been reported to be associated with PCI, although fluorouracil-related PCI is extremely rare. We report a case of a 76-year old man who received adjuvant chemotherapy for rectal cancer with fluorouracil (FU) and leucovorin (LV). After 1 cycle of the treatment, he presented with diarrhea and abdominal pain. Abdominal radiogram revealed the presence of free air under the diaphragm and intramural gas in the intestine. Laparotomy was performed, showing a suspected diagnosis of perforation in the gastrointestinal tract. Intraoperative findings revealed penumatosis of the intestine without evidence of perforation. He was treated supportively and his symptoms improved. In conclusion, we should consider the possibility of PCI occurring in patients with malignancies during chemotherapy treatment.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Mimatsu K,Oida T,Kawasaki A,Kano H,Kuboi Y,Aramaki O,Amano Sdoi
10.3748/wjg.14.3273subject
Has Abstractpub_date
2008-05-28 00:00:00pages
3273-5issue
20eissn
1007-9327issn
2219-2840journal_volume
14pub_type
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pub_type: 临床试验,杂志文章
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
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