Epidemiology and natural history of hepatitis C virus infection.

abstract：AIM:To elucidate high mobility group-box 3 (HMGB3) protein expression in gastric adenocarcinoma, its potential prognostic relevance, and possible mechanism of action. METHODS:Ninety-two patients with gastric adenocarcinomas surgically removed entered the study. HMGB3 expression was determined by immunohistochemistry t...

journal_title：World journal of gastroenterology

authors： Tang HR,Luo XQ,Xu G,Wang Y,Feng ZJ,Xu H,Shi YW,Zhang Q,Wu LG,Xue CQ,Wang CW,Wu CY

更新日期：2012-12-28 00:00:00

abstract：:AIM:To study the clinical significance of the diagnosis and catheterized interventional treatment of digital subtraction angiography (DSA) for pancreatic tumors.METHODS: Ninety-two patients with pancreatic tumor, 69 males and 23 females, aged from 41 to 70 years (mean 57.1 years) were diagnosed with DSA. Sixty-one pat...

journal_title：World journal of gastroenterology

authors： Xu HB,Zhang YJ,Wei WJ,Li WM,Tu XQ

更新日期：1998-02-01 00:00:00

abstract：:Hemolymphangioma is a malformation of both lymphatic vessels and blood vessels. Splenic hemolymphangioma is extremely rare. Herein, we present a case of 62-year-old woman with ambiguous upper quadrant abdominal pain for two months who was found to have an occupying lesion in the spleen on computed tomography. She was ...

journal_title：World journal of gastroenterology

authors： Mei Y,Peng CJ,Chen L,Li XX,Li WN,Shu DJ,Xie WT

更新日期：2015-05-07 00:00:00

abstract：AIM:To investigate the feasibility of detecting methylated fecal DNA as a screening tool for colorectal carcinoma (CRC) and precancerous lesions. METHODS:Methylated secreted frizzled-related protein gene 2 (SFRP2), hyperplastic polyposis protein gene (HPP1) and O6-methylguanine-DNA methyltransferase gene (MGMT) in sto...

journal_title：World journal of gastroenterology

authors： Huang ZH,Li LH,Yang F,Wang JF

更新日期：2007-02-14 00:00:00

abstract：AIM:To evaluate the impact of sociodemographic/clinical factors on early virological response (EVR) to peginterferon/ribavirin for chronic hepatitis C (CHC) in clinical practice. METHODS:We conducted a multicenter, cross-sectional, observational study in Hepatology Units of 91 Spanish hospitals. CHC patients treated w...

journal_title：World journal of gastroenterology

authors： García-Samaniego J,Romero M,Granados R,Alemán R,Jorge Juan M,Suárez D,Pérez R,Castellano G,González-Portela C

更新日期：2013-03-28 00:00:00

abstract：AIM:To develop a conditionally replicative gene-viral vector system called CNHK500-p53, which contains dual promoters within the E1 region, and combines the advantages of oncolytic virus and gene therapies for hepatocellular carcinoma (HCC). METHODS:CNHK500-p53 was constructed by using human telomerase reverse transcr...

journal_title：World journal of gastroenterology

authors： Zhao HC,Zhang Q,Yang Y,Lu MQ,Li H,Xu C,Chen GH

更新日期：2007-02-07 00:00:00

abstract：AIM:To develop a sensitive assay for screening compounds against hepatitis C virus (HCV). METHODS:The proteolytic cleavage of NS3/4A on enhanced yellow fluorescent protein (eYFP)-mitochondrial antiviral signaling protein (MAVS) was examined by reporter enzyme secreted placental alkaline phosphatase (SEAP), which enabl...

journal_title：World journal of gastroenterology

authors： Fu QX,Wang LC,Jia SZ,Gao B,Zhou Y,Du J,Wang YL,Wang XH,Peng JC,Zhan LS

更新日期：2010-11-28 00:00:00

abstract：AIM:To investigate Helicobacter pylori (H. pylori) eradication rates using second-line bismuth-containing quadruple therapy and to identify predictors of eradication failure. METHODS:This study included 636 patients who failed first-line triple therapy and received 7 d of bismuth-containing quadruple therapy between J...

journal_title：World journal of gastroenterology

authors： Kim SE,Park MI,Park SJ,Moon W,Kim JH,Jung K,Kim HK,Lee YD

更新日期：2017-02-14 00:00:00

abstract：AIM:To evaluate the value of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) level for predicting postoperative atrial fibrillation (AF) in patients undergoing surgery for esophageal carcinoma. METHODS:NT-proBNP levels were measured in 142 patients 24 h before and 1 h after surgery for esophageal carcinoma...

journal_title：World journal of gastroenterology

authors： Hou JL,Gao K,Li M,Ma JY,Shi YK,Wang Y,Zhao YF

更新日期：2008-04-28 00:00:00

abstract：:Tumor necrosis factor-α (TNF-α) inhibitors are known to increase reactivation of concurrent chronic hepatitis B, but their impact on the hepatitis C virus (HCV) is controversial. Some conditions of immunosuppression, such as liver transplantation, typically cause an increase in the rate of HCV evolution. Inhibition of...

journal_title：World journal of gastroenterology

authors： Pompili M,Biolato M,Miele L,Grieco A

更新日期：2013-11-28 00:00:00

abstract：AIM:To investigate omeprazole-induced transepithelial gastric leak and its effects on the permeability of the peptides bradykinin and oxytocin. METHODS:Rat gastric corpus tissue was isolated and mounted in an Ussing chamber apparatus to evaluate the permeability of (3)H-bradykinin, (3)H-oxytocin, and (14)C-EDTA in the...

journal_title：World journal of gastroenterology

authors： Gabello M,Valenzano MC,Zurbach EP,Mullin JM

更新日期：2010-03-07 00:00:00

abstract：BACKGROUND:At our academic tertiary care medical center, we have noted patients referred for endoscopic retrograde cholangiopancreatography (ERCP) who increasingly require advanced cannulation techniques. This trend is noted despite increased endoscopist experience and annual ERCP volume over the same period. AIM:To e...

journal_title：World journal of gastroenterology

authors： Barakat MT,Girotra M,Thosani N,Kothari S,Banerjee S

更新日期：2020-11-07 00:00:00

abstract：AIM:To investigate the changes of gut microflora and endotoxin levels in rats with acute liver failure (ALF) induced by D-galactosamine (GalN). METHODS:Flora and endotoxin levels in the jejunum, ileum and colon in normal rats (group A) and rats with GalN -induced ALF were determined at 24 h (group B) or 48 h (group C)...

journal_title：World journal of gastroenterology

authors： Li LJ,Wu ZW,Xiao DS,Sheng JF

更新日期：2004-07-15 00:00:00

abstract：:Inflammatory bowel disease (IBD) results from the interaction between an individual's immune response and precipitant environmental factors, which generate an anomalous chronic inflammatory response in those who are genetically predisposed. Various feeding practices have been implicated in the origin of IBD based on e...

journal_title：World journal of gastroenterology

authors： Lucendo AJ,De Rezende LC

更新日期：2009-05-07 00:00:00

abstract：:Inflammatory bowel diseases (IBD) can be really considered to be systemic diseases since they are often associated with extraintestinal manifestations, complications, and other autoimmune disorders. Indeed, physicians who care for patients with ulcerative colitis and Crohn's disease, the two major forms of IBD, face a...

journal_title：World journal of gastroenterology

authors： Danese S,Semeraro S,Papa A,Roberto I,Scaldaferri F,Fedeli G,Gasbarrini G,Gasbarrini A

更新日期：2005-12-14 00:00:00

abstract：:Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. The identification of colonic polyps can reduce CRC mortality through earlier diagnosis of cancers and the removal of polyps: the precursor lesion of CRC. Following the finding and removal of colonic polyps at an initial colonoscopy, some p...

journal_title：World journal of gastroenterology

authors： Bonnington SN,Rutter MD

更新日期：2016-02-14 00:00:00

abstract：AIM:To investigate the underlying molecular mechanisms of miR-451 to inhibit proliferation of esophageal carcinoma cell line EC9706. METHODS:Assays for cell growth, apoptosis and invasion were used to evaluate the effects of miR-451 expression on EC cells. Luciferase reporter and Western blot assays were used to test ...

journal_title：World journal of gastroenterology

authors： Zang WQ,Yang X,Wang T,Wang YY,Du YW,Chen XN,Li M,Zhao GQ

更新日期：2015-05-21 00:00:00

abstract：AIM:To investigate the pharmacological effect of TongXie-YaoFang (TXYF) formula, a Chinese herbal formula, on Diarrhea-predominant irritable bowel syndrome (D-IBS) rats. METHODS:In a neonatal maternal separation plus restraint stress (NMS + RS) model of D-IBS, male Sprague Dawley rats were randomly divided into two gr...

journal_title：World journal of gastroenterology

authors： Yang C,Xiong Y,Zhang SS,An FM,Sun J,Zhang QL,Zhan Q

更新日期：2016-12-28 00:00:00

abstract：:Crohn's disease (CD) is a chronic inflammatory disease of the digestive tract with systemic manifestations. Etiology is unknown, even if immunological, genetic and environmental factors are involved. The majority of CD patients require surgery during their lifetime due to progressive bowel damage, but, even when all m...

journal_title：World journal of gastroenterology

authors： Spinelli A,Sacchi M,Fiorino G,Danese S,Montorsi M

更新日期：2011-07-21 00:00:00

abstract：AIM:To assess the clinicopathological characteristics of duodenal well-differentiated endocrine tumors. METHODS:We examined clinicopathological characteristics in 11 consecutive patients with duodenal well-differentiated endocrine tumors treated by endoscopic therapy or surgery in our hospital from 1992 through 2007. ...

journal_title：World journal of gastroenterology

authors： Ishido K,Tanabe S,Higuchi K,Sasaki T,Katada C,Azuma M,Naruke A,Koizumi W,Mikami T

更新日期：2010-09-28 00:00:00

abstract：AIM:To evaluate the application of bipolar coagulation (BIP) in hepatectomy by comparing the efficacy of BIP alone, cavitron ultrasonic surgical aspirator (CUSA) + BIP and conventional clamp crushing (CLAMP). METHODS:Based on our database of patient records, a total of 380 consecutive patients who underwent hepatectom...

journal_title：World journal of gastroenterology

authors： Guo JY,Li DW,Liao R,Huang P,Kong XB,Wang JM,Wang HL,Luo SQ,Yan X,Du CY

更新日期：2014-07-14 00:00:00

abstract：:Eosinophilic esophagitis has rapidly become a recognized entity causing dysphagia in young adults. This review summarizes the current knowledge of eosinophilic esophagitis including the epidemiology, clinical presentation, diagnostic criteria, pathophysiology, treatment, and prognosis. An extensive search of PubMed/Me...

journal_title：World journal of gastroenterology

authors： Yan BM,Shaffer EA

更新日期：2006-04-21 00:00:00

abstract：AIM:To investigate the association of tumor necrosis factor alpha (TNFα) -G308A polymorphism with different liver pathological changes in treatment-naïve Egyptian patients infected with hepatitis C virus (HCV) genotype 4. METHODS:This study included 180 subjects, composed of 120 treatment-naïve chronic HCV patients wi...

journal_title：World journal of gastroenterology

authors： Bader El Din NG,Farouk S,El-Shenawy R,Ibrahim MK,Dawood RM,Elhady MM,Salem AM,Zayed N,Khairy A,El Awady MK

更新日期：2016-09-14 00:00:00

abstract：AIM:To elucidate the different serological reactions to H pylori using the immunoblotting technique for further understanding of its pathogenic role in gastric cancer. METHODS:A total of 54 patients were divided into two groups after upper gastrointestinal endoscopy: normal control group (25 patients) and gastric canc...

journal_title：World journal of gastroenterology

authors： Yang KC,Chu A,Liao CS,Lin YM,Wang GM

更新日期：2006-11-21 00:00:00

abstract：AIM:To investigate the ultrastructure of abnormal hepatocyte mitochondria, including their cellular and hepatic zonal distribution, in bioptates in pediatric non-alcoholic steatohepatitis (NASH). METHODS:Ultrastructural investigations were conducted on biopsy liver specimens obtained from 10 children (6 boys and 4 gir...

journal_title：World journal of gastroenterology

authors： Lotowska JM,Sobaniec-Lotowska ME,Bockowska SB,Lebensztejn DM

更新日期：2014-04-21 00:00:00

abstract：:Chronic pancreatitis (CP) continues to be a clinical challenge. Persistent or recurrent abdominal pain is the most compelling symptom that drives patients to seek medical care. Unfortunately, in spite of using several treatment approaches in the clinical setting, there is no single specific treatment modality that can...

journal_title：World journal of gastroenterology

authors： Talukdar R,Reddy DN

更新日期：2013-10-14 00:00:00

abstract：:Pelvic radiation is a commonly utilized treatment for malignancy of the genitourinary and lower gastrointestinal tract. Radiation proctitis and the resultant clinical picture varies from asymptomatic to potentially life threatening. Similarly, treatment options also vary greatly, from medical therapy to surgical inter...

journal_title：World journal of gastroenterology

authors： Weiner JP,Wong AT,Schwartz D,Martinez M,Aytaman A,Schreiber D

更新日期：2016-08-21 00:00:00

abstract：AIM:To investigate the effects of osteopontin (OPN) gene expression knockdown on colon cancer Lovo cells in vitro. METHODS:Four candidate small interfering RNA (siRNA) constructs targeting the OPN gene and a scrambled control sequence (NC-siRNA) were synthesized and inserted into a pGPU6/GFP/Neo expression vector. Aft...

journal_title：World journal of gastroenterology

authors： Wu XL,Lin KJ,Bai AP,Wang WX,Meng XK,Su XL,Hou MX,Dong PD,Zhang JJ,Wang ZY,Shi L

更新日期：2014-08-14 00:00:00

abstract：AIM:To investigate the relationship between autophagy and perineural invasion (PNI), clinical features, and prognosis in patients with pancreatic cancer. METHODS:Clinical and pathological data were retrospectively collected from 109 patients with pancreatic ductal adenocarcinoma who underwent radical resection at the ...

journal_title：World journal of gastroenterology

authors： Yang YH,Liu JB,Gui Y,Lei LL,Zhang SJ

更新日期：2017-10-28 00:00:00

abstract：:Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is frequently associated with type 1 autoimmune pancreatitis (AIP). Association with AIP can be utilized in the diagnosis of IgG4-SC. However, some cases of IgG4-SC are isolated from AIP, which complicates the diagnosis. Most of the reported cases of isolated ...

journal_title：World journal of gastroenterology

authors： Nakazawa T,Ikeda Y,Kawaguchi Y,Kitagawa H,Takada H,Takeda Y,Makino I,Makino N,Naitoh I,Tanaka A

更新日期：2015-01-28 00:00:00