Clinicopathological evaluation of duodenal well-differentiated endocrine tumors.

Abstract:

AIM:To assess the clinicopathological characteristics of duodenal well-differentiated endocrine tumors. METHODS:We examined clinicopathological characteristics in 11 consecutive patients with duodenal well-differentiated endocrine tumors treated by endoscopic therapy or surgery in our hospital from 1992 through 2007. Patients with well-differentiated endocrine tumors of the papilla of Vater or with gastrinoma were excluded. RESULTS:Three patients received endoscopic treatment, and 8 underwent surgery. In patients who received endoscopic treatment, the tumor diameter was less than 1.0 cm, with no histopathological evidence of lymphovascular invasion or invasion of the muscularis. There were no complications such as late bleeding or perforation after treatment. Among 8 patients with tumors less than 1.0 cm in diameter, 3 underwent partial resection, and 2 underwent radical surgery. Three patients had lymphovascular invasion, 1 had invasion of the muscularis, and 1 had proximal lymph node metastasis. Among 3 patients with tumors 1.0 cm or more in diameter, 1 underwent partial resection, and 2 underwent radical surgery. One patient had lymphovascular invasion, with no lymph node metastasis. After treatment, all patients are alive and have remained free of metastasis and recurrence. CONCLUSION:Duodenal well-differentiated endocrine tumors less than 1.0 cm in diameter have a risk of lymphovascular invasion, invasion of the muscularis, and lymph node metastasis, irrespective of procedural problems.

journal_name

World J Gastroenterol

authors

Ishido K,Tanabe S,Higuchi K,Sasaki T,Katada C,Azuma M,Naruke A,Koizumi W,Mikami T

doi

10.3748/wjg.v16.i36.4583

subject

Has Abstract

pub_date

2010-09-28 00:00:00

pages

4583-8

issue

36

eissn

1007-9327

issn

2219-2840

journal_volume

16

pub_type

杂志文章
  • Intra-abdominal drainage following pancreatic resection: A systematic review.

    abstract:AIM:To study all the aspects of drain management in pancreatic surgery. METHODS:We conducted a systematic review according to the PRISMA guidelines. We searched the Cochrane Central Registry of Controlled Trials, EMBASE, Web of Science, and PubMed (MEDLINE) for relevant articles on drain management in pancreatic surge...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i40.11458

    authors: Čečka F,Loveček M,Jon B,Skalický P,Šubrt Z,Neoral Č,Ferko A

    更新日期:2015-10-28 00:00:00

  • JNKs, insulin resistance and inflammation: A possible link between NAFLD and coronary artery disease.

    abstract::The incidence of obesity has dramatically increased in recent years. Consequently, obesity and associated disorders such as nonalcoholic fatty liver disease constitute a serious problem. Therefore, the contribution of adipose tissue to metabolic homeostasis has become a focus of interest. In this review, we discuss th...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v17.i33.3785

    authors: Tarantino G,Caputi A

    更新日期:2011-09-07 00:00:00

  • Mucosa repair mechanisms of Tong-Xie-Yao-Fang mediated by CRH-R2 in murine, dextran sulfate sodium-induced colitis.

    abstract:AIM:To explore the significance of corticotropin-releasing hormone (CRH)-receptor (R)2 in mucosal healing of dextran sulfate sodium (DSS)-induced colitis and the effect of Tong-Xie-Yao-Fang (TXYF) on CRH-R2 expression and regulation. METHODS:Ulcerative colitis was induced in mice by administration of 3% (w/v) DSS for ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i16.1766

    authors: Gong SS,Fan YH,Wang SY,Han QQ,Lv B,Xu Y,Chen X,He YE

    更新日期:2018-04-28 00:00:00

  • Co-occurrence of carbohydrate malabsorption and primary epiploic appendagitis.

    abstract::Unspecific abdominal complaints including bloating and irregular bowel movements may be caused by carbohydrate malabsorption syndromes, e.g., lactose and fructose malabsorption. These symptoms were investigated with hydrogen (H2) breath tests and correlated to carbohydrate malabsorption. During performing these H2-bre...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i35.10242

    authors: Schnedl WJ,Kalmar P,Mangge H,Krause R,Wallner-Liebmann SJ

    更新日期:2015-09-21 00:00:00

  • Research progress of vasculopathy in portal hypertension.

    abstract::Portal hypertension, one of the vascular diseases, not only has lesions in liver, but also changes in vascular structures and functions of extrahepatic portal system, systemic system and pulmonary circulation. The pathological changes of vasculopathy in portal hypertension include remodeling of arterialized visceral v...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v11.i39.6079

    authors: Li T,Yang Z

    更新日期:2005-10-21 00:00:00

  • Importance of performance status for treatment outcome in advanced pancreatic cancer.

    abstract::Despite progress in the treatment of advanced and metastatic pancreatic cancer (PC), the outcome of this disease remains dismal for the majority of patients. Given the moderate efficacy of treatment, prognostic factors may help to guide treatment decisions. Several trials identified baseline performance status as an i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v13.i2.224

    authors: Boeck S,Hinke A,Wilkowski R,Heinemann V

    更新日期:2007-01-14 00:00:00

  • Management of acute pancreatitis in Japan: Analysis of nationwide epidemiological survey.

    abstract::Acute pancreatitis (AP) is an acute inflammatory disease of the exocrine pancreas. In Japan, nationwide epidemiological surveys have been conducted every 4 to 5 years by the Research Committee of Intractable Pancreatic Diseases, under the support of the Ministry of Health, Labour, and Welfare of Japan. We reviewed the...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v22.i28.6335

    authors: Hamada S,Masamune A,Shimosegawa T

    更新日期:2016-07-28 00:00:00

  • Human epidermal growth factor receptor-2 in oesophageal cancers: an observational study.

    abstract:AIM:To determine the incidence of human epidermal growth factor receptor 2 (HER2) over expression in oesophageal cancers. METHODS:A retrospective study, of one hundred consecutive cases of endoscopic histological samples of oesophageal cancers from a single British cancer network were included. Cancer cases were diagn...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i44.6447

    authors: Al-Momani H,Barnes R,El-Hadi A,Shah R,Lewis WG,Edwards P

    更新日期:2012-11-28 00:00:00

  • Expression changes of activin A in the development of hepatic fibrosis.

    abstract:AIM:To examine the expression of activin A, a member of the transforming growth factor (TGFbeta) superfamily, recently has been reported to be overexpressed in liver cirrhosis, in the course of carbon tetrachloride-induced rat hepatic fibrosis. METHODS:Hepatic fibrosis was induced in rats by subcutaneous injections of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v7.i1.37

    authors: Huang X,Li DG,Wang ZR,Wei HS,Cheng JL,Zhan YT,Zhou X,Xu QF,Li X,Lu HM

    更新日期:2001-02-01 00:00:00

  • Protons pump inhibitor treatment and lower gastrointestinal bleeding: Balancing risks and benefits.

    abstract::Proton pump inhibitors (PPIs) represent a milestone in the treatment of acid-related diseases, and are the mainstay in preventing upper gastrointestinal bleeding in high-risk patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin. However, this beneficial effect does not extend to the ...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v22.i48.10477

    authors: Lué A,Lanas A

    更新日期:2016-12-28 00:00:00

  • Effect of neoadjuvant chemoradiotherapy on prognosis and surgery for esophageal carcinoma.

    abstract:AIM:To investigate the role of neoadjuvant chemoradiotherapy in prognosis and surgery for esophageal carcinoma by a meta-analysis. METHODS:PubMed and manual searches were done to identify all published randomized controlled trials (RCTs) that compared neoadjuvant chemoradiotherapy plus surgery (CRTS) with surgery alon...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析,评审

    doi:10.3748/wjg.15.4962

    authors: Lv J,Cao XF,Zhu B,Ji L,Tao L,Wang DD

    更新日期:2009-10-21 00:00:00

  • Seropharmalogical effects of Fuzheng Huayu decoction on rat Ito cell morphology and function in culture.

    abstract:AIM:To investigate the mechanisms of anti-liver fibrosis actions of Fuzheng Huayu (FZHY) decoction, which acts to strengthen the body's resistance and promote blood circulation. METHODS:Ito cells were isolated from rats and cultured. Serum samples were collected from healthy (normal) rats after administration of FZHY ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v3.i4.263

    authors: Liu CH,Liu C,Liu P,Xu LM

    更新日期:1997-12-15 00:00:00

  • Delta-like ligand 4 in hepatocellular carcinoma intrinsically promotes tumour growth and suppresses hepatitis B virus replication.

    abstract:AIM:To investigate the role of Delta-like ligand 4 (DLL4) on tumour growth in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) in vivo. METHODS:We suppressed DLL4 expression in an HBV expressing HCC cell line, HepG2.2.15 and analysed the growth ability of cells as subcutaneous tumours in nude mice. Th...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i34.3861

    authors: Kunanopparat A,Issara-Amphorn J,Leelahavanichkul A,Sanpavat A,Patumraj S,Tangkijvanich P,Palaga T,Hirankarn N

    更新日期:2018-09-14 00:00:00

  • Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma.

    abstract:AIM:To investigate the relationship between c.343A>G and c.2216A>C polymorphism sites in the CDH17 gene and colorectal carcinoma. METHODS:Ninety-three non-consanguineous colorectal carcinoma patients admitted to the Department of Oncology at the First Affiliated Hospital of Zhengzhou University were included in this s...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i48.7251

    authors: Chen RY,Cao JJ,Chen J,Yang JP,Liu XB,Zhao GQ,Zhang YF

    更新日期:2012-12-28 00:00:00

  • Enhanced expressions and activations of leukotriene C4 synthesis enzymes in D-galactosamine/lipopolysaccharide-induced rat fulminant hepatic failure model.

    abstract:AIM:To investigate the expression and activity of leukotriene C4 (LTC4) synthesis enzymes and their underlying relationship with cysteinyl leukotriene (cys-LT) generation in a rat fulminant hepatic failure (FHF) model induced by D-galactosamine/lipopolysaccharide (D-GalN/ LPS). METHODS:Rats were treated with D-GalN (3...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.2748

    authors: Ma KF,Yang HY,Chen Z,Qi LY,Zhu DY,Lou YJ

    更新日期:2008-05-07 00:00:00

  • Approach to the endoscopic resection of duodenal lesions.

    abstract::Duodenal polyps or lesions are uncommonly found on upper endoscopy. Duodenal lesions can be categorized as subepithelial or mucosally-based, and the type of lesion often dictates the work-up and possible therapeutic options. Subepithelial lesions that can arise in the duodenum include lipomas, gastrointestinal stromal...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i2.600

    authors: Gaspar JP,Stelow EB,Wang AY

    更新日期:2016-01-14 00:00:00

  • Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats.

    abstract:BACKGROUND:Irritable bowel syndrome (IBS) is a common chronic non-organic disease of the digestive system. Berberine (BBR) has been used to treat patients with IBS, but the underlying therapeutic mechanism is little understood. We believe that BBR achieves its therapeutic effect on IBS by preventing stress intestinal i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i29.3956

    authors: Yu ZC,Cen YX,Wu BH,Wei C,Xiong F,Li DF,Liu TT,Luo MH,Guo LL,Li YX,Wang LS,Wang JY,Yao J

    更新日期:2019-08-07 00:00:00

  • Resection of the uncinate process of the pancreas due to a ganglioneuroma.

    abstract::A 33-year-old woman who presented with epigastric discomfort and diarrhea underwent an abdominal ultrasound (US). This investigation and subsequent contrast-enhanced computed tomography, magnetic resonance imaging and endoscopic US with fine needle aspiration (FNA) revealed a 40 mm well-circumscribed mass in the uncin...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.4334

    authors: Poves I,Burdío F,Iglesias M,Martínez-Serrano Mde L,Aguilar G,Grande L

    更新日期:2009-09-14 00:00:00

  • Overview and comparison of guidelines for management of pancreatic cystic neoplasms.

    abstract::Pancreatic cysts are identified at an increasing frequency. Although mucinous cystic neoplasms represent a pre-malignant condition, the majority of these lesions do not progress to cancer. Over the last 10 years several societies have established guidelines for the diagnosis, initial evaluation and surveillance of the...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v25.i31.4405

    authors: Hasan A,Visrodia K,Farrell JJ,Gonda TA

    更新日期:2019-08-21 00:00:00

  • Regional variation of pediatric inflammatory bowel disease in Saudi Arabia: Results from a multicenter study.

    abstract:BACKGROUND:Incidence and severity variations of inflammatory bowel disease (IBD) have been reported from Western populations between continents and regions of the same countries. However, no data were available from other countries. AIM:To investigate the regional differences in the IBD profiles of pediatric patients ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v26.i4.416

    authors: El Mouzan MI,AlEdreesi MH,Hasosah MY,Al-Hussaini AA,Al Sarkhy AA,Assiri AA

    更新日期:2020-01-28 00:00:00

  • Mycobacterium avium subspecies paratuberculosis causes Crohn's disease in some inflammatory bowel disease patients.

    abstract::Crohn's disease (CD) is a chronic inflammatory condition that plagues millions all over the world. This debilitating bowel disease can start in early childhood and continue into late adulthood. Signs and symptoms are usually many and multiple tests are often required for the diagnosis and confirmation of this disease....

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i23.7403

    authors: Naser SA,Sagramsingh SR,Naser AS,Thanigachalam S

    更新日期:2014-06-21 00:00:00

  • Bile acid increases expression of the histamine-producing enzyme, histidine decarboxylase, in gastric cells.

    abstract:AIM:To investigate the effect of bile acid on the expression of histidine decarboxylase (HDC), which is a major enzyme involved in histamine production, and gene expression of gastric transcription factors upon cooperative activation. METHODS:HDC expression was examined by immunohistochemistry, reverse transcriptase p...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i1.175

    authors: Ku HJ,Kim HY,Kim HH,Park HJ,Cheong JH

    更新日期:2014-01-07 00:00:00

  • α-fetoprotein, vascular endothelial growth factor receptor-1 and early recurrence of hepatoma.

    abstract:AIM:To investigate whether α-fetoprotein (AFP) and vascular endothelial growth factor receptor (VEGFR)-1 correlate with early recurrence of hepatoma/hepatocellular carcinoma (HCC). METHODS:From 2000 to 2005, 114 consecutive patients with HCC underwent primary curative hepatectomy. The mean age was 60.7 (8.7) years and...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i4.340

    authors: Kamiyama T,Takahashi M,Nakanishi K,Yokoo H,Kamachi H,Kobayashi N,Ozaki M,Todo S

    更新日期:2012-01-28 00:00:00

  • Effect of Jianweiyuyang granule on gastric ulcer recurrence and expression of VEGF mRNA in the healing process of gastric ulcer in rats.

    abstract:AIM:To investigate the effect of Jianweiyuyang (JWYY) granule on gastric ulcer recurrence and its mechanism in the treatment of gastric ulcer in rats. METHODS:Gastric ulcer in rats was induced according to Okeba's method with minor modification and the recurrence model was induced by IL-1beta. The expression of vascul...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i35.5480

    authors: Dai XP,Li JB,Liu ZQ,Ding X,Huang CH,Zhou B

    更新日期:2005-09-21 00:00:00

  • In-vivo characterization of DALM in ulcerative colitis with high-resolution probe-based confocal laser endomicroscopy.

    abstract::Recently, the use of confocal laser endomicroscopy (CLE) in the diagnosis of chronic ulcerative colitis (CUC) was reported. In this brief report we aimed to assess the application of probe-based CLE to characterize colonic mucosa and dysplasia in CUC. The study involved a patient presenting long-standing CUC. Confocal...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i5.677

    authors: De Palma GD,Staibano S,Siciliano S,Maione F,Siano M,Esposito D,Persico G

    更新日期:2011-02-07 00:00:00

  • Risk factors associated with inflammatory bowel disease: A multicenter case-control study in Brazil.

    abstract:BACKGROUND:The etiology of inflammatory bowel disease (IBD) is unknown, but it is believed to be multifactorial. The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases. AIM:To test the hygiene hypothesi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i25.3611

    authors: Salgado VCL,Luiz RR,Boéchat NLF,Leão IS,Schorr BDC,Parente JML,Lima DC,Silveira Júnior ES,Silva GOS,Almeida NP,Vieira A,de Bueno MLQ,Chebli JM,Bertges ÉR,Brugnara LMDC,Junqueira Neto C,Campbell SBG,Discacciati LL,Céza

    更新日期:2020-07-07 00:00:00

  • Translational research in pancreatic ductal adenocarcinoma: current evidence and future concepts.

    abstract::Pancreatic ductal adenocarcinoma (PDA) is one of the major causes for cancer death worldwide. Treatment of metastatic disease remains challenging as only certain patients benefit from advances made with the intensified chemotherapy regimen folinic acid, irinotecan and oxaliplatin, the epidermal growth factor receptor ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i31.10769

    authors: Kruger S,Haas M,Ormanns S,Bächmann S,Siveke JT,Kirchner T,Heinemann V,Boeck S

    更新日期:2014-08-21 00:00:00

  • Mesenteric inflammatory myofibroblastic tumors in an elder patient with early recurrence: a case report.

    abstract::Inflammatory myofibroblastic tumor (IMT) of the alimentary tract often occurs in children or young adults, but may occur at any age. Symptoms are nonspecific and depend on the location of the tumor. The most often involved sites are small bowel mesentery especially the distal ileum, mesotransverse colon, or great omen...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i26.3645

    authors: Chen SS,Liu SI,Mok KT,Wang BW,Yeh MH,Chen YC,Chen IS

    更新日期:2007-07-14 00:00:00

  • Transhepatic catheter-directed thrombolysis for portal vein thrombosis after partial splenic embolization in combination with balloon-occluded retrograde transvenous obliteration of splenorenal shunt.

    abstract::A 66-year-old woman underwent partial splenic embolization (PSE) for hypersplenism with idiopathic portal hypertension (IPH). One week later, contrast-enhanced CT revealed extensive portal vein thrombosis (PVT) and dilated portosystemic shunts. The PVT was not dissolved by the intravenous administration of urokinase. ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i31.5071

    authors: Nakai M,Sato M,Sahara S,Kawai N,Kimura M,Maeda Y,Ibata Y,Higashi K

    更新日期:2006-08-21 00:00:00

  • Multidrug-resistant bacterial infections after liver transplantation: an ever-growing challenge.

    abstract::Bacterial infections are a leading cause of morbidity and mortality among solid organ transplant recipients. Over the last two decades, various multidrug-resistant (MDR) pathogens have emerged as relevant causes of infection in this population. Although this fact reflects the spread of MDR pathogens in health care fac...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i20.6201

    authors: Santoro-Lopes G,de Gouvêa EF

    更新日期:2014-05-28 00:00:00