In-vivo characterization of DALM in ulcerative colitis with high-resolution probe-based confocal laser endomicroscopy.

Abstract:

:Recently, the use of confocal laser endomicroscopy (CLE) in the diagnosis of chronic ulcerative colitis (CUC) was reported. In this brief report we aimed to assess the application of probe-based CLE to characterize colonic mucosa and dysplasia in CUC. The study involved a patient presenting long-standing CUC. Confocal imaging of both the inflamed mucosa, a circumscribed lesion (dysplasia-associated lesional mass), and adjacent colonic mucosa are demonstrated and the correlation between the CLE and histological images. Inflamed mucosa and dysplasia showed specific alteration of crypt architecture, cellular infiltration, and vessel architecture with an excellent correlation between CLE and standard histological examination.

journal_name

World J Gastroenterol

authors

De Palma GD,Staibano S,Siciliano S,Maione F,Siano M,Esposito D,Persico G

doi

10.3748/wjg.v17.i5.677

subject

Has Abstract

pub_date

2011-02-07 00:00:00

pages

677-80

issue

5

eissn

1007-9327

issn

2219-2840

journal_volume

17

pub_type

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