Role of gut microbiota via the gut-liver-brain axis in digestive diseases.

abstract：:The evasion from controlled cell death induction has been considered as one of the hallmarks of cancer cells. Defects in cell death signaling are a fundamental phenomenon in colorectal cancer. Nearly any non-invasive cancer treatment finally aims to induce cell death. However, apoptosis resistance is the major cause f...

journal_title：World journal of gastroenterology

authors： Koehler BC,Jäger D,Schulze-Bergkamen H

更新日期：2014-02-28 00:00:00

abstract：:Microscopic colitis may be defined as a clinical syndrome, of unknown etiology, consisting of chronic watery diarrhea, with no alterations in the large bowel at the endoscopic and radiologic evaluation. Therefore, a definitive diagnosis is only possible by histological analysis. The epidemiological impact of this dise...

journal_title：World journal of gastroenterology

authors： Ianiro G,Cammarota G,Valerio L,Annicchiarico BE,Milani A,Siciliano M,Gasbarrini A

更新日期：2012-11-21 00:00:00

abstract：AIM:To evaluate the efficacy and safety of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) with undifferentiated-type histology. METHODS:A systematic literature review was conducted using the core databases. Complete resection, curative resection, en bloc resection, recurrence and adverse event r...

journal_title：World journal of gastroenterology

authors： Bang CS,Baik GH,Shin IS,Kim JB,Suk KT,Yoon JH,Kim YS,Kim DJ,Shin WG,Kim KH,Kim HY,Lim H,Kang HS,Kim JH,Kim JB,Jung SW,Kae SH,Jang HJ,Choi MH

更新日期：2015-05-21 00:00:00

abstract：:The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), may be complicated by colorectal cancer (CRC). In a recent population-based cohort study of 47 347 Danish patients with IBD by Tine Jess and colleagues 268 patients with UC and 70 patients with CD developed CRC during 30 years of ...

journal_title：World journal of gastroenterology

authors： Andersen V,Halfvarson J,Vogel U

更新日期：2012-08-21 00:00:00

abstract：:Diffuse liver hemangiomatosis with giant cavernous hemangioma in adult is extremely rare. A 35 year-old woman presented to hospital with main complaint of epigastric pain and abdominal fullness. An enhanced computed tomography scan revealed a massive liver tumor in right lobe about 150 mm in size. There was contrast e...

journal_title：World journal of gastroenterology

authors： Ohkura Y,Hashimoto M,Lee S,Sasaki K,Matsuda M,Watanabe G

更新日期：2014-07-07 00:00:00

abstract：:Gastric intramural hematoma is a rare injury of the stomach, and is most often seen in patients with underlying disease. Such injury following endoscopic therapy is even rarer, and there are no universally accepted guidelines for its treatment. In this case report, we describe a gastric intramural hematoma which occur...

journal_title：World journal of gastroenterology

authors： Sun P,Tan SY,Liao GH

更新日期：2012-12-21 00:00:00

abstract：:Investigation of the possible role of Campylobacter concisus (C. concisus) in inflammatory bowel disease (IBD) is an emerging research area. Despite the association found between C. concisus and IBD, it has been difficult to explain how C. concisus, a bacterium that is commonly present in the human oral cavity, may co...

journal_title：World journal of gastroenterology

authors： Zhang L,Lee H,Grimm MC,Riordan SM,Day AS,Lemberg DA

更新日期：2014-02-07 00:00:00

abstract：AIM:To understand the role of toll-like receptor 4 (TLR4) signaling in the regulation of iron-regulatory hormone, hepcidin by chronic alcohol consumption. METHODS:For chronic alcohol intake studies, TLR4 mutant mice on C3H/HeJ background and wildtype counterpart on C3H/HeOuJ background were pair-fed with regular (cont...

journal_title：World journal of gastroenterology

authors： Zmijewski E,Lu S,Harrison-Findik DD

更新日期：2014-09-14 00:00:00

abstract：:Ulcerative colitis (UC) is an inflammatory destructive disease of the large intestine occurred usually in the rectum and lower part of the colon as well as the entire colon. Drug therapy is not the only choice for UC treatment and medical management should be as a comprehensive whole. Azulfidine, Asacol, Pentasa, Dipe...

journal_title：World journal of gastroenterology

authors： Xu CT,Meng SY,Pan BR

更新日期：2004-08-15 00:00:00

abstract：:Proton pump inhibitors (PPIs) represent a milestone in the treatment of acid-related diseases, and are the mainstay in preventing upper gastrointestinal bleeding in high-risk patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin. However, this beneficial effect does not extend to the ...

journal_title：World journal of gastroenterology

authors： Lué A,Lanas A

更新日期：2016-12-28 00:00:00

abstract：:Esophageal cancer is an aggressive malignancy associated with dismal treatment outcomes. Presence of two distinct histopathological types distinguishes it from other gastrointestinal tract malignancies. Surgery is the cornerstone of treatment in locally advanced esophageal cancer (T2 or greater or node positive); howe...

journal_title：World journal of gastroenterology

authors： Garg PK,Sharma J,Jakhetiya A,Goel A,Gaur MK

更新日期：2016-10-21 00:00:00

abstract：:Acute hepatic failure due to hepatitis B virus (HBV) can occur both during primary infection as well as after reactivation of chronic infection. Guidelines recommend considering antiviral therapy in both situations, although evidence supporting this recommendation is weak. Since HBV is not directly cytopathic, the mec...

journal_title：World journal of gastroenterology

authors： Bockmann JH,Dandri M,Lüth S,Pannicke N,Lohse AW

更新日期：2015-02-21 00:00:00

abstract：:Occult hepatitis B virus (HBV) infection (OBI), alternatively defined as occult hepatitis B (OHB), is a challenging clinical entity. It is recognized by two main characteristics: absence of HBsAg, and low viral replication. The previous two decades have witnessed a remarkable progress in our understanding of OBI and i...

journal_title：World journal of gastroenterology

authors： Said ZN

更新日期：2011-04-21 00:00:00

abstract：:Colorectal cancer remains the third most common cancer in both women and men worldwide. Identifying modifiable dietary factors is crucial in developing primary prevention strategies. Vitamin B6 is involved in more than 100 coenzyme reactions, and may influence colorectal cancer risk in multiple ways including through ...

journal_title：World journal of gastroenterology

authors： Zhang XH,Ma J,Smith-Warner SA,Lee JE,Giovannucci E

更新日期：2013-02-21 00:00:00

abstract：AIM:To investigate the effect of side-stream smoking on gut microflora composition, intestinal inflammation and expression of tight junction proteins. METHODS:C57BL/6 mice were exposed to side-stream cigarette smoking for one hour daily over eight weeks. Cecal contents were collected for microbial composition analysis...

journal_title：World journal of gastroenterology

authors： Wang H,Zhao JX,Hu N,Ren J,Du M,Zhu MJ

更新日期：2012-05-14 00:00:00

abstract：AIM:To test the Genval recommendations and the usefulness of a short trial of proton pump inhibitor (PPI) in the initial management and maintenance treatment of gastroesophageal reflux disease (GERD) patients. METHODS:Five hundred and seventy seven patients with heartburn were recruited. After completing a psychometri...

journal_title：World journal of gastroenterology

authors： Pace F,Riegler G,de Leone A,Dominici P,Grossi E,EMERGE Study Group.

更新日期：2011-03-07 00:00:00

abstract：AIM:To determine whether local antibiotic resistance involves P-glycoprotein (Pgp)-mediated active drug out-pumping during Helicobacter pylori (H pylori) infection treatment with classic antibiotic therapy. METHODS:Pgp activity was determined in gastric mucosa biopsy specimens obtained from 53 patients with pathohisto...

journal_title：World journal of gastroenterology

authors： Babic Z,Svoboda-Beusan I,Kucisec-Tepes N,Dekaris D,Troskot R

更新日期：2005-05-14 00:00:00

abstract：BACKGROUND:Non-invasive evaluation for liver fibrosis is clinically important, especially in patients with undetectable hepatitis B virus (HBV) DNA treated with nucleoside analogs. AIM:To clarify the monitoring power of hepatitis B core-related antigen (HBcrAg) for hepatic histologic changes in patients with chronic h...

journal_title：World journal of gastroenterology

authors： Chang XJ,Sun C,Chen Y,Li XD,Yu ZJ,Dong Z,Bai WL,Wang XD,Li ZQ,Chen D,Du WJ,Liao H,Jiang QY,Sun LJ,Li YY,Zhang CH,Xu DP,Chen YP,Li Q,Yang YP

更新日期：2019-08-28 00:00:00

abstract：AIM:To understand the molecular mechanism of esophageal cancer development and provide molecular markers for screening high-risk populations and early diagnosis. METHODS:Two-dimensional electrophoresis combined with mass spectrometry were adopted to screen differentially expressed proteins in nine cases of fetal esoph...

journal_title：World journal of gastroenterology

authors： Guo JH,Xing GL,Fang XH,Wu HF,Zhang B,Yu JZ,Fan ZM,Wang LD

更新日期：2017-02-28 00:00:00

abstract：AIM:To characterize the expression and dynamic changes of bone morphogenetic protein (BMP)-2 in hepatocytes in the regenerating liver in rats after partial hepatectomy (PH), and examine the effects of BMP-2 on proliferation of human Huh7 hepatoma cells. METHODS:Fifty-four adult male Wistar rats were randomly divided i...

journal_title：World journal of gastroenterology

authors： Xu CP,Ji WM,van den Brink GR,Peppelenbosch MP

更新日期：2006-12-21 00:00:00

abstract：AIM:To review the usefulness of endoscopic biliary stenting for obstructive jaundice caused by hepatocellular carcinoma and identify problems that may need to be addressed. METHODS:The study population consisted of 36 patients with obstructive jaundice caused by hepatocellular carcinoma (HCC) who underwent endoscopic ...

journal_title：World journal of gastroenterology

authors： Sugiyama G,Okabe Y,Ishida Y,Saitou F,Kawahara R,Ishikawa H,Horiuchi H,Kinoshita H,Tsuruta O,Sata M

更新日期：2014-06-14 00:00:00

abstract：:AIM:To explore the status of extrahepatic hepatitis C virus (HCV) infection and replication in hepatitis C patients,and its potential implication in HCV infection and pathogenicity.METHODS:By reverse-transcriptase poly-merase chain reaction (RT-PCR),in situ hybridization (ISH) and immunohis-tochemistry, HCV RNA, HCV r...

journal_title：World journal of gastroenterology

authors： Yan FM,Chen AS,Hao F,Zhao XP,Gu CH,Zhao LB,Yang DL,Hao LJ

更新日期：2000-12-01 00:00:00

abstract：:Although thousands of DNA damaging events occur in each cell every day, efficient DNA repair pathways have evolved to counteract them. The DNA repair machinery plays a key role in maintaining genomic stability by avoiding the maintenance of mutations. The DNA repair enzymes continuously monitor the chromosomes to corr...

journal_title：World journal of gastroenterology

authors： Santos JC,Ribeiro ML

更新日期：2015-08-14 00:00:00

abstract：AIM:To assess the safety of bismuth used in Helicobacter pylori (H pylori) eradication therapy regimens. METHODS:We conducted a systematic review and meta-analysis. MEDLINE and EMBASE were searched (up to October 2007) to identify randomised controlled trials comparing bismuth with placebo or no treatment, or bismuth ...

journal_title：World journal of gastroenterology

authors： Ford AC,Malfertheiner P,Giguere M,Santana J,Khan M,Moayyedi P

更新日期：2008-12-28 00:00:00

abstract：:AIM:To study the peripheral mechanism of the inhibitory effect of intra-third ventricular administration (icv) of histamine (HA) on gastric acid secretion in rats.METHODS:Gastric acid was continuously washed with 37&mgr; saline by a perfusion pump in male adrenalectomized SD rats. Drugs were injected intravenously (iv...

journal_title：World journal of gastroenterology

authors： Zhang ZF,Wang ZL,Lu GQ

更新日期：1998-06-01 00:00:00

abstract：AIM:To explore the mechanism for interactions of leptin with ghrelin and orexin in the arcuate nucleus (ARC) activating neuropeptide Y (NPY) neurons during physiological regulation of feeding. METHODS:Single neurons from ARC of adult rats with matured feeding function were isolated. [Ca2+]i was measured to monitor the...

journal_title：World journal of gastroenterology

authors： Kohno D,Suyama S,Yada T

更新日期：2008-11-07 00:00:00

abstract：:Eosinophilic gastroenteritis (EG) is an uncommon disease characterized by focal or diffuse eosinophilic infiltration of the gastrointestinal tract, and is usually associated with dyspepsia, diarrhea and peripheral eosinophilia. Diffuse gastrointestinal tract and colonic involvement are uncommon. The endoscopic appeara...

journal_title：World journal of gastroenterology

authors： Sheikh RA,Prindiville TP,Pecha RE,Ruebner BH

更新日期：2009-05-07 00:00:00

abstract：AIM:To evaluate the effect of preoperative transcatheter arterial chemoembolization (TACE) on proliferation of hepatocellular carcinoma (HCC) cells. METHODS:A total of 136 patients with HCC underwent liver resection. Of 136 patients, 79 patients received 1 to 5 courses of TACE prior to liver resection (TACE group), wh...

journal_title：World journal of gastroenterology

authors： Xiao EH,Li JQ,Huang JF

更新日期：2007-09-07 00:00:00

abstract：:Because of the low prevalence of non-ampullary duodenal epithelial tumors (NADETs), standardized clinical management of sporadic superficial NADETs, including diagnosis, treatment, and follow-up, has not yet been established. Retrospective studies have revealed certain endoscopic findings suggestive of malignancy. Duo...

journal_title：World journal of gastroenterology

authors： Kakushima N,Kanemoto H,Tanaka M,Takizawa K,Ono H

更新日期：2014-09-21 00:00:00

abstract：AIM:To compare the performance of the Da-an real-time hepatitis B virus (HBV) DNA assay and Abbott RealTime HBV assay. METHODS:HBV DNA standards as well as a total of 180 clinical serum samples from patients with chronic hepatitis B were measured using the Abbott and Da-an real-time polymerase chain reaction (PCR) ass...

journal_title：World journal of gastroenterology

authors： Qiu N,Li R,Yu JG,Yang W,Zhang W,An Y,Li T,Liu XE,Zhuang H

更新日期：2014-09-07 00:00:00