Prevalence and characteristics of dyspepsia among college students in Zhejiang Province.

Abstract:

AIM:To investigate the prevalence and characteristics of uninvestigated dyspepsia among college students in Zhejiang Province. METHODS:Young adult students attending undergraduate (within the 4-year program) and graduate (only first-year students) colleges in Zhejiang Province were recruited between November 2010 and March 2011 to participate in the self-report survey study. The questionnaire was designed to collect data regarding demographics (sex and age), general health [weight and height, to calculate body mass index (BMI)], and physical episodes related to gastrointestinal disorders. Diagnosis of dyspepsia and irritable bowel syndrome (IBS) was made according to the Rome III criteria. Gastroesophageal reflux disease (GERD) was defined by episodes of heartburn and/or acid reflux that occurred at least once a week, according to the Montreal definition. RESULTS:Of 2520 students recruited for survey participation, only 1870 (males: 967; age range: 17-32 years, mean age: 21.3 years) returned a completed questionnaire. One hundred and eight (5.67%) of the student participants fit the criteria for dyspepsia diagnosis. Stratification analysis of dyspepsia and non-dyspepsia cases showed no statistically significant differences in age or BMI; however, the prevalence of dyspepsia was significantly higher in women than in men (7.53% vs 4.14%, P < 0.05). Stratification analysis of dyspepsia by grade level showed that year 4 undergraduate students had a significantly higher prevalence of dyspepsia (10.00% vs undergraduate year 1: 5.87%, year 2: 3.53% and year 3: 7.24%, and graduate year 1: 3.32%). Nearly all (95.37%) students with dyspepsia reported symptoms of postprandial distress syndrome, but only a small portion (4.63%) reported symptoms suggestive of abdominal pain syndrome. The students with dyspepsia also showed significantly higher rates of IBS (16.67% vs non-dyspepsia students: 6.30%, P < 0.05) and GERD (11.11% vs 0.28%, P < 0.05). CONCLUSION:Although the prevalence of dyspepsia among Zhejiang college students is low, the significantly higher rates of concomitant IBS and GERD suggest common pathophysiological disturbances.

journal_name

World J Gastroenterol

authors

Li M,Lu B,Chu L,Zhou H,Chen MY

doi

10.3748/wjg.v20.i13.3649

subject

Has Abstract

pub_date

2014-04-07 00:00:00

pages

3649-54

issue

13

eissn

1007-9327

issn

2219-2840

journal_volume

20

pub_type

杂志文章
  • Gastroenterology service in a teaching hospital in rural New Zealand, 1991-2003.

    abstract:AIM:To retrospectively collect inpatient and outpatient data and to assess the use of endoscopic procedures during the years 1991, 1997 and 2003 to analyse for trends. METHODS:This retrospective survey was conducted in a University-associated Gastroenterology Unit offering secondary and tertiary health care services f...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.583

    authors: Schultz M,Davidson A,Donald S,Targonska B,Turnbull A,Weggery S,Livingstone V,Dockerty JD

    更新日期:2009-02-07 00:00:00

  • Effects of short-term application of low-dose growth hormone on trace element metabolism and blood glucose in surgical patients.

    abstract:AIM:To investigate the effects of short-term application of low-dose growth hormone on trace element metabolism and blood glucose in surgical patients. METHODS:A total of 48 consecutive patients undergoing abdominal operations were randomized to receive either subcutaneous rhGH (0.15 IU/kg) or placebo (menstruum) inje...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v13.i46.6259

    authors: Qian K,Wan Z,Hao LS,Zhang MM,Zhou Y,Wu XT

    更新日期:2007-12-14 00:00:00

  • Severe acute cholestatic hepatitis of unknown etiology successfully treated with the Chinese herbal medicine Inchinko-to (TJ-135).

    abstract::Severe acute hepatitis of unknown etiology is difficult to treat and often progresses to subacute fulminant hepatitis or late-onset hepatic failure. A 45-year-old well-nourished, healthy man had progressive fatigue and his liver function tests showed severe liver dysfunction. The etiology of sever acute cholestatic he...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.2927

    authors: Ohwada S,Kobayashi I,Harasawa N,Tsuda K,Inui Y

    更新日期:2009-06-21 00:00:00

  • Neoadjuvant chemoradiotherapy followed by D2 gastrectomy in locally advanced gastric cancer.

    abstract:AIM:To investigate the efficacy of neoadjuvant chemoradiotherapy (NACRT) for resectability of locally advanced gastric cancer (LAGC). METHODS:Between November 2007 and January 2014, 29 patients with LAGC (clinically T3 with distal esophagus invasion/T4 or bulky regional node metastasis) that were treated with NACRT fo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i9.2711

    authors: Kim MS,Lim JS,Hyung WJ,Lee YC,Rha SY,Keum KC,Koom WS

    更新日期:2015-03-07 00:00:00

  • Study of human B7 homolog 1 expression in patients with hepatitis B virus infection.

    abstract:AIM:To further investigate the role of human B7 homolog 1 (B7-H1) in the mechanism of persistent hepatitis B virus (HBV) infection. METHODS:Peripheral and intra-hepatic B7-H1 expression were compared by flow cytometry and immunochemical staining between two 2 distinct groups, one being chronic HBV tolerance patients (C...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i28.3681

    authors: Zhang WJ,Xie HY,Duan X,Wan YL,Peng CH,Shi SH,Su R,Zheng ZH,Pan LL,Zhou L,Zheng SS

    更新日期:2012-07-28 00:00:00

  • Genes, emotions and gut microbiota: The next frontier for the gastroenterologist.

    abstract::Most medical specialties including the field of gastroenterology are mainly aimed at treating diseases rather than preventing them. Genomic medicine studies the health/disease process based on the interaction of the human genes with the environment. The gastrointestinal (GI) system is an ideal model to analyze the int...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v23.i17.3030

    authors: Panduro A,Rivera-Iñiguez I,Sepulveda-Villegas M,Roman S

    更新日期:2017-05-07 00:00:00

  • Expression changes of activin A in the development of hepatic fibrosis.

    abstract:AIM:To examine the expression of activin A, a member of the transforming growth factor (TGFbeta) superfamily, recently has been reported to be overexpressed in liver cirrhosis, in the course of carbon tetrachloride-induced rat hepatic fibrosis. METHODS:Hepatic fibrosis was induced in rats by subcutaneous injections of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v7.i1.37

    authors: Huang X,Li DG,Wang ZR,Wei HS,Cheng JL,Zhan YT,Zhou X,Xu QF,Li X,Lu HM

    更新日期:2001-02-01 00:00:00

  • Expression of cyclooxygenase-2 in gastric cancer and its relation to liver metastasis and long-term prognosis.

    abstract:AIM:To investigate the expression of cyclooxygenase-2 (COX-2) in gastric cancer and its relation with the liver metastasis and prognosis. METHODS:Expression of COX-2 mRNA and protein was examined in gastric cancer and its paired substantial normal tissue by semi-quantitative reverse transcription-polymerase chain reac...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i31.4911

    authors: Yu JR,Wu YJ,Qin Q,Lu KZ,Yan S,Liu XS,Zheng SS

    更新日期:2005-08-21 00:00:00

  • Management of acute pancreatitis in Japan: Analysis of nationwide epidemiological survey.

    abstract::Acute pancreatitis (AP) is an acute inflammatory disease of the exocrine pancreas. In Japan, nationwide epidemiological surveys have been conducted every 4 to 5 years by the Research Committee of Intractable Pancreatic Diseases, under the support of the Ministry of Health, Labour, and Welfare of Japan. We reviewed the...

    journal_title:World journal of gastroenterology

    pub_type: 社论

    doi:10.3748/wjg.v22.i28.6335

    authors: Hamada S,Masamune A,Shimosegawa T

    更新日期:2016-07-28 00:00:00

  • Colorectal cancer and 18FDG-PET/CT: what about adding the T to the N parameter in loco-regional staging?

    abstract:AIM:To evaluate whether FDG-positron emission tomography (PET)/computed tomography (CT) may be an accurate technique in the assessment of the T stage in patients with colorectal cancer. METHODS:Thirty four consecutive patients (20 men and 14 women; mean age: 63 years) with a histologically proven diagnosis of colorect...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i11.1427

    authors: Mainenti PP,Iodice D,Segreto S,Storto G,Magliulo M,De Palma GD,Salvatore M,Pace L

    更新日期:2011-03-21 00:00:00

  • Barrett's metaplasia: clinical implications.

    abstract::The incidence of Barrett's metaplasia (BM) as well as Barrett's adenocarcinoma (BA) has been increasing in western populations. The prognosis of BA is worse because individuals present at a late stage. Attempts have been made to intervene at early stage using surveillance programmes, although proof of efficacy of endo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v7.i4.563

    authors: Ishaq S,Jankowski JA

    更新日期:2001-08-01 00:00:00

  • Effects of autoantibodies against beta(1)-adrenoceptor in hepatitis virus myocarditis on action potential and L-type Ca(2+) currents.

    abstract:AIM:To investigate the effects of autoantibodies against beta(1)-adrenoceptor in hepatitis virus myocarditis on action potential and L-type Ca(2+) currents. METHODS:Fifteen samples of autoantibodies against beta(1)-adrenoceptor positive sera of patients with hepatitis virus myocarditis were obtained and IgGs were puri...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i8.1171

    authors: Liu K,Liao YH,Wang ZH,Li SL,Wang M,Zeng LL,Tang M

    更新日期:2004-04-15 00:00:00

  • Relationship between tumor necrosis factor-alphaand liver fibrosis.

    abstract::INTRODUCTION:To intrestigate the relationship between tumor necrosis factor-alphaand liver fibrosis in patients with chronic liver disease.METHODS:Radioimmunoassay was made in 20 patients with mild chronic hepatitis(CMH),20 patients with severe chronic hepatitis(CSH),51 patients with liver cirrhosis(LC)and 32-normal p...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v4.i1.18

    authors: Wang X,Chen YX,Xu CF,Zhao GN,Huang YX,Wang QL

    更新日期:1998-02-01 00:00:00

  • Downregulation of electroacupuncture at ST36 on TNF-alpha in rats with ulcerative colitis.

    abstract:AIM:To investigate the regulatory effect of electroacupuncture (EA) at Zusanli (ST36) on tumor necrosis factor-alpha (TNF-alpha) in rats with ulcerative colitis (UC), and further elucidate the therapeutic mechanism of EA on UC. METHODS:Thirty-two male Sprague-Dawley (SD) rats were randomly divided into four groups (n=...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i5.1028

    authors: Tian L,Huang YX,Tian M,Gao W,Chang Q

    更新日期:2003-05-01 00:00:00

  • Experimental obstructive jaundice alters claudin-4 expression in intestinal mucosa: effect of bombesin and neurotensin.

    abstract:AIM:To investigate the influence of experimental obstructive jaundice and exogenous bombesin (BBS) and neurotensin (NT) administration on the expression of the tight junction (TJ)-protein claudin-4 in intestinal epithelium of rats. METHODS:Forty male Wistar rats were randomly divided into five groups: I = controls, II...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i21.3410

    authors: Assimakopoulos SF,Vagianos CE,Charonis AS,Alexandris IH,Spiliopoulou I,Thomopoulos KC,Nikolopoulou VN,Scopa CD

    更新日期:2006-06-07 00:00:00

  • Retrospective analysis of extra-gastrointestinal stromal tumors.

    abstract:AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors (EGISTs) in South Korea. METHODS:A total of 51 patients with an EGIST were identified. The clinicopathologic features, including sex, age, location, tumor size, histology, mitotic rate, immunohistochemical features...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i6.1845

    authors: Yi JH,Park BB,Kang JH,Hwang IG,Shin DB,Sym SJ,Ahn HK,Lee SI,Lim DH,Park KW,Won YW,Lim SH,Park SH

    更新日期:2015-02-14 00:00:00

  • Possible causes of central pontine myelinolysis after liver transplantation.

    abstract:AIM:To sum up the clinical characteristics of patients with central pontine myelinolysis (CPM) after orthotopic liver transplantation (OLT) and to document the possible causes of CPM. METHODS:Data of 142 patients undergoing OLT between January 1999 to May 2003 were analyzed retrospectively. Following risk factors duri...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i17.2540

    authors: Yu J,Zheng SS,Liang TB,Shen Y,Wang WL,Ke QH

    更新日期:2004-09-01 00:00:00

  • Clinical usefulness of adherence to gastro-esophageal reflux disease guideline by Spanish gastroenterologists.

    abstract:AIM:To investigate usefulness of adherence to gastro-esophageal reflux disease (GERD) guideline established by the Spanish Association of Gastroenterology. METHODS:Prospective, observational and multicentre study of 301 patients with typical symptoms of GERD who should be managed in accordance with guidelines and were...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v18.i35.4885

    authors: Mearin F,Ponce J,Ponce M,Balboa A,González MA,Zapardiel J

    更新日期:2012-09-21 00:00:00

  • Omeprazole induces gastric transmucosal permeability to the peptide bradykinin.

    abstract:AIM:To investigate omeprazole-induced transepithelial gastric leak and its effects on the permeability of the peptides bradykinin and oxytocin. METHODS:Rat gastric corpus tissue was isolated and mounted in an Ussing chamber apparatus to evaluate the permeability of (3)H-bradykinin, (3)H-oxytocin, and (14)C-EDTA in the...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i9.1097

    authors: Gabello M,Valenzano MC,Zurbach EP,Mullin JM

    更新日期:2010-03-07 00:00:00

  • Clearance of hepatitis C virus after living-donor liver transplantation in spite of residual viremia on end date of interferon therapy before transplantation.

    abstract::Interferon (IFN) therapy is the only treatment strategy for hepatitis C virus (HCV) infection after liver transplantation (LT), but prophylactic and treatable IFN therapy after LT has been shown to be insufficient due to the adverse effects of IFN and rivabirin. In this paper, we describe the disappearance of HCV afte...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i30.4149

    authors: Ichikawa T,Nakao K,Hamasaki K,Honda T,Shibata H,Akahoshi M,Eguchi S,Takatsuki M,Kanematsu T,Eguchi K

    更新日期:2007-08-14 00:00:00

  • Diversity of Saccharomyces boulardii CNCM I-745 mechanisms of action against intestinal infections.

    abstract::The yeast Saccharomyces boulardii CNCM I-745 is one of the probiotics recommended for the prevention of antibiotic-associated diarrhea. Studies conducted in vivo and in vitro demonstrated that in the case of infectious diseases there are two potential sites of action of Saccharomyces boulardii CNCM I-745: (1) An actio...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v25.i18.2188

    authors: Czerucka D,Rampal P

    更新日期:2019-05-14 00:00:00

  • Identification of TRPM7 channels in human intestinal interstitial cells of Cajal.

    abstract:AIM:To investigate the characteristics of slow electrical waves and the presence of transient receptor potential melastatin-type 7 (TRPM7) in the human gastrointestinal (GI) tract. METHODS:Conventional microelectrode techniques were used to record intracellular electrical responses from human GI smooth muscle tissue. ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.5799

    authors: Kim BJ,Park KJ,Kim HW,Choi S,Jun JY,Chang IY,Jeon JH,So I,Kim SJ

    更新日期:2009-12-14 00:00:00

  • Estrogens and the pathophysiology of the biliary tree.

    abstract::The scientific framework concerning estrogen effects on different tissues has expanded enormously during the last decades, when estrogen receptor (ER) subtypes were identified. Estrogens are not only essential for the female reproductive system, but they also control fundamental functions in other tissues including th...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v12.i22.3537

    authors: Alvaro D,Mancino MG,Onori P,Franchitto A,Alpini G,Francis H,Glaser S,Gaudio E

    更新日期:2006-06-14 00:00:00

  • Activation of canonical Wnt signaling pathway promotes proliferation and self-renewal of rat hepatic oval cell line WB-F344 in vitro.

    abstract:AIM:To investigate the effect of activation of canonical Wnt signaling pathway on the proliferation and differentiation of hepatic oval cells in vitro. METHODS:WB-F344 cells were treated with recombinant Wnt3a (20, 40, 80, 160, 200 ng/mL) in serum-free medium for 24 h. Cell proliferation was measured by Brdu incorpora...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.6673

    authors: Zhang Y,Li XM,Zhang FK,Wang BE

    更新日期:2008-11-21 00:00:00

  • Impact of alcohol on hepatitis C virus replication and interferon signaling.

    abstract::Hepatitis C virus (HCV) is one of the main etiological factors responsible for liver disease worldwide. It has been estimated that there are over 170 million people infected with HCV worldwide. Of these infected individuals, approximately 75% will go on to develop a life long necroinflammatory liver disease, which ove...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v16.i11.1337

    authors: McCartney EM,Beard MR

    更新日期:2010-03-21 00:00:00

  • Low RASSF6 expression in pancreatic ductal adenocarcinoma is associated with poor survival.

    abstract:AIM:To analyze RASSF6 expression in pancreatic ductal adenocarcinoma (PDAC) and to determine whether RASSF6 has an independent prognostic value in PDAC. METHODS:We studied RASSF6 expression in 96 histologically confirmed PDAC samples and 20 chronic pancreatitis specimens using immunohistochemistry and real-time quanti...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i21.6621

    authors: Ye HL,Li DD,Lin Q,Zhou Y,Zhou QB,Zeng B,Fu ZQ,Gao WC,Liu YM,Chen RW,Li ZH,Chen RF

    更新日期:2015-06-07 00:00:00

  • Short-term overlap lamivudine treatment with adefovir dipivoxil in patients with lamivudine-resistant chronic hepatitis B.

    abstract:AIM:To evaluate the efficacy of short-term overlap lamivudine therapy with adefovir in patients with lamivudine-resistant and naive chronic hepatitis B, we compared patients receiving overlap therapy with those receiving adefovir alone. METHODS:Eighty patients who had received lamivudine treatment for various periods ...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.14.1781

    authors: Nam SW,Bae SH,Lee SW,Kim YS,Kang SB,Choi JY,Cho SH,Yoon SK,Han JY,Yang JM,Lee YS

    更新日期:2008-03-21 00:00:00

  • Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis.

    abstract:AIM:To examine the protective effect of green tea extract (GT) on hepatic fibrosis in vitro and in vivo in dimethylnitrosamine (DMN)-induced rats. METHODS:HSC-T6, a rat hepatic stellate cell line, was used as an in vitro assay system. Cell proliferation, collagen content, and type 1 collagen expression were examined i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.5200

    authors: Kim HK,Yang TH,Cho HY

    更新日期:2009-11-07 00:00:00

  • Nestin in gastrointestinal and other cancers: effects on cells and tumor angiogenesis.

    abstract::Nestin is a class VI intermediate filament protein that was originally described as a neuronal stem cell marker during central nervous system (CNS) development, and is currently widely used in that capacity. Nestin is also expressed in non-neuronal immature or progenitor cells in normal tissues. Under pathological con...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v17.i4.409

    authors: Ishiwata T,Matsuda Y,Naito Z

    更新日期:2011-01-28 00:00:00

  • STW 5 is effective against nonsteroidal anti-inflammatory drugs induced gastro-duodenal lesions in rats.

    abstract:BACKGROUND:Proton pump inhibitors are often used to prevent gastro-intestinal lesions induced by nonsteroidal anti-inflammatory drugs. However, they are not always effective against both gastric and duodenal lesions and their use is not devoid of side effects. AIM:To explore the mechanisms mediating the clinical effic...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i39.5926

    authors: Khayyal MT,Wadie W,Abd El-Haleim EA,Ahmed KA,Kelber O,Ammar RM,Abdel-Aziz H

    更新日期:2019-10-21 00:00:00