Colorectal cancer with liver metastases: neoadjuvant chemotherapy, surgical resection first or palliation alone?

abstract：AIM:To study the efficacy and factors associated with a sustained virological response (SVR) in chronic hepatitis C (CHC) relapsing patients. METHODS:Out of 1228 CHC patients treated with pegylated interferon (PEG-IFN) and ribavirin (RBV), 165 (13%) had a relapse. Among these, 62 patients were retreated with PEG-IFN-α...

journal_title：World journal of gastroenterology

authors： Stern C,Martinot-Peignoux M,Ripault MP,Boyer N,Castelnau C,Valla D,Marcellin P

更新日期：2012-06-21 00:00:00

abstract：AIM:To investigate whether illness severity has an impact on gastric residual volume (GRV) in medical critically ill patients. METHODS:Medical intensive care unit (ICU) patients requiring nasogastric feeding were enrolled. Sequential Organ Failure Assessment (SOFA) score was assessed immediately preceding the start of...

journal_title：World journal of gastroenterology

authors： Hsu CW,Sun SF,Lee DL,Lin SL,Wong KF,Huang HH,Li HJ

更新日期：2011-04-21 00:00:00

abstract：AIM:To investigate if transnasal endoscopic retrograde cholangiopancreatography (n-ERCP) using an ultrathin forward-viewing scope may overcome the disadvantages of conventional oral ERCP (o-ERCP) related to the large-caliber side-viewing duodenoscope. METHODS:The study involved 50 patients in whom 25 cases each were a...

journal_title：World journal of gastroenterology

authors： Mori A,Ohashi N,Maruyama T,Tatebe H,Sakai K,Shibuya T,Inoue H,Takegoshi S,Okuno M

更新日期：2008-03-14 00:00:00

abstract：AIM:To evaluate the association between HLA-DRB1 alleles and Han and Uyghur ulcerative colitis (UC) patients residing in the Xinjiang Uyghur Autonomous Region of China. METHODS:In this study, 102 UC patients (53 Han including 22 men and 31 women, and 49 Uyghur patients including 25 men and 24 women; aged 48.07 ± 15.83...

journal_title：World journal of gastroenterology

authors： Aheman A,Gao F,Kuerbanjiang A,Li YX,Abuduhadeer M

更新日期：2013-05-07 00:00:00

abstract：:In mammals, the intestinal epithelium is a tissue that contains two distinct pools of stem cells: active intestinal stem cells and reserve intestinal stem cells. The former are located in the crypt basement membrane and are responsible for maintaining epithelial homeostasis under intact conditions, whereas the latter ...

journal_title：World journal of gastroenterology

authors： Cui S,Chang PY

更新日期：2016-08-21 00:00:00

abstract：AIM:To determine the association of human antigen R (HuR) and inhibitors of apoptosis proteins (IAP1, IAP2) and prognosis in pancreatic cancer. METHODS:Protein and mRNA expression levels of IAP1, IAP2 and HuR in pancreatic ductal adenocarcinoma (PDAC) were compared with normal pancreatic tissue. The correlations among...

journal_title：World journal of gastroenterology

authors： Lukosiute-Urboniene A,Jasukaitiene A,Silkuniene G,Barauskas V,Gulbinas A,Dambrauskas Z

更新日期：2019-01-14 00:00:00

abstract：AIM:To clarify the effectiveness of plasma exchange by comparing the mortality and morbidity before and after the intervention of plasma exchange. METHODS:Plasma exchange has been available as an optional therapy for hyperlipidemic pancreatitis since August 1999 in our hospital. The patients were assorted into 2 group...

journal_title：World journal of gastroenterology

authors： Chen JH,Yeh JH,Lai HW,Liao CS

更新日期：2004-08-01 00:00:00

abstract：:Many of the drugs currently used in medical practice are racemates. The enantiomers of a racemic drug differ in pharmacodynamics and/or pharmacokinetics, thus in some cases it is preferable to develop pure enantiomers by racemic switch. In a recent study by Pai et al, dexrabeprazole [R(+)-rabeprazole] (10 mg) was foun...

journal_title：World journal of gastroenterology

authors： Zhou Q,Yan XF,Pan WS,Zeng S

更新日期：2008-04-28 00:00:00

abstract：:Fibroblast growth factor receptors (FGFRs) regulate a variety of cellular functions, from embryogenesis to adult tissue homeostasis. FGFR signaling also plays significant roles in the proliferation, invasion, and survival of several types of tumor cells. FGFR-induced alterations, including gene amplification, chromoso...

journal_title：World journal of gastroenterology

authors： Yashiro M,Matsuoka T

更新日期：2016-02-28 00:00:00

abstract：AIM:Allo-cell transplant rejection and autoimmune responses were associated with the presence of class II major histocompatibility complex (MHC II) molecules on cells. This paper studied the effect of Ribonuclease P (RNase P) against CIITA, which was a major regulator of MHCII molecules, on repressing the expression of...

journal_title：World journal of gastroenterology

authors： Guo R,Zou P,Fan HH,Gao F,Shang QX,Cao YL,Lu HZ

更新日期：2003-05-01 00:00:00

abstract：AIM:To study the expression of ether à go-go (Eag1) potassium channel in colorectal cancer and the relation-ship between their expression and clinico-pathological features. METHODS:The expression levels of Eag1 protein were determined in 76 cancer tissues with paired non-cancerous matched tissues as well as 9 colorect...

journal_title：World journal of gastroenterology

authors： Ding XW,Yan JJ,An P,Lü P,Luo HS

更新日期：2007-02-28 00:00:00

abstract：AIM:To investigate the expression of the transforming growth factor beta 1(TGF-beta 1) mRNA in different stages of alcoholic liver disease (ALD) and its clinical value. METHODS:One hundred and seven male alcoholics were grouped by clinical findings into four groups: alcohol abusers without liver impairment (n =22), al...

journal_title：World journal of gastroenterology

authors： Chen WX,Li YM,Yu CH,Cai WM,Zheng M,Chen F

更新日期：2002-04-01 00:00:00

abstract：:The prognosis of patients with HCC still remains dismal. The life expectancy of HCC patients is hard to predict because of the high possibility of postoperative recurrence. Many factors, such as patient's general conditions, macroscopic tumor morphology, as well as tumor histopathology features, have been proven of pr...

journal_title：World journal of gastroenterology

authors： Qin LX,Tang ZY

更新日期：2002-04-01 00:00:00

abstract：AIM:To investigate the effects of combined use of emodin and baicalein (CEB) at the cellular and organism levels in severe acute pancreatitis (SAP) and explore the underlying mechanism. METHODS:SAP was induced by retrograde infusion of 5% sodium taurocholate into the pancreatic duct in 48 male SD rats. Pancreatic hist...

journal_title：World journal of gastroenterology

authors： Li J,Zhou R,Bie BB,Huang N,Guo Y,Chen HY,Shi MJ,Yang J,Zhang J,Li ZF

更新日期：2018-01-07 00:00:00

abstract：:AIM:To observe the changes in oxygen free radical (OFR) and the curative effect of traditional Chinese medicine Qing Yi Tang in acute necrotizing pancreatitis (ANP).METHODS:After induction of ANP by injection of sodium taurocholate into pancreatic duct, 16 dogs were randomly divided into control group and Chinese medi...

journal_title：World journal of gastroenterology

authors： Li ZL,Wu CT,Lu LR,Zhu XF,Xiong DX

更新日期：1998-08-01 00:00:00

abstract：:Mechanical lithotripsy (ML) is usually considered as a standard treatment option for large bile duct stones. However, it is impossible to retrieve oversized stones because the conventional lithotripsy basket may not be able to grasp the stone. However, there is no established endoscopic extraction method for such gian...

journal_title：World journal of gastroenterology

authors： Chung HJ,Jeong S,Lee DH,Lee JI,Lee JW,Bang BW,Kwon KS,Kim HK,Shin YW,Kim YS

更新日期：2012-07-07 00:00:00

abstract：:The continued need to develop less invasive alternatives to surgical and radiologic interventions has driven the development of endoscopic ultrasound (EUS)-guided treatments. These include EUS-guided drainage of pancreatic fluid collections, EUS-guided necrosectomy, EUS-guided cholangiography and biliary drainage, EUS...

journal_title：World journal of gastroenterology

authors： Fabbri C,Luigiano C,Lisotti A,Cennamo V,Virgilio C,Caletti G,Fusaroli P

更新日期：2014-07-14 00:00:00

abstract：:Transplantation cannot be considered the most important therapeutic procedure for hepatocellular carcinoma (HCC). In France, no more than 2% of patients with HCC undergo a transplantation. Randomized controlled trial must assess the benefit to risk ratio of various potentially "curative" treatment procedures (transpla...

journal_title：World journal of gastroenterology

authors： Braillon A

更新日期：2009-11-14 00:00:00

abstract：:AIM:To study the peripheral mechanism of the inhibitory effect of intra-third ventricular administration (icv) of histamine (HA) on gastric acid secretion in rats.METHODS:Gastric acid was continuously washed with 37&mgr; saline by a perfusion pump in male adrenalectomized SD rats. Drugs were injected intravenously (iv...

journal_title：World journal of gastroenterology

authors： Zhang ZF,Wang ZL,Lu GQ

更新日期：1998-06-01 00:00:00

abstract：:A liver tumor 35 mm in diameter was found incidentally in a 40-year-old woman who had no history of liver diseases or the use of oral contraceptives. Radiological diagnostics showed the typical findings of liver cell adenoma (LCA). Dynamic computed tomography revealed that the tumor showed a homogenous enhancement in ...

journal_title：World journal of gastroenterology

authors： Kogure T,Ueno Y,Sekiguchi S,Ishida K,Igarashi T,Wakui Y,Iwasaki T,Shimosegawa T

更新日期：2009-03-14 00:00:00

abstract：:The risk factors for hepatocellular carcinoma (HCC) development have been established, and include chronic hepatitis B and C, heavy alcohol consumption, and aflatoxins. In fact, 5%-30% of patients with HCC still lack a readily identifiable risk factor. It has been reported that the majority of ''cryptogenic'' HCC may ...

journal_title：World journal of gastroenterology

authors： Wang SN,Lee KT,Ker CG

更新日期：2010-12-14 00:00:00

abstract：AIM:To investigate expression of microRNA (miRNA) and potential targets in chemotherapy resistant esophageal cancer cell lines. METHODS:An in-vitro model of acquired chemotherapy resistance in esophageal adeno- (EAC) and squamous cell carcinoma (ESCC) cells was used, and microRNA expression profiles for cisplatin or 5...

journal_title：World journal of gastroenterology

authors： Hummel R,Sie C,Watson DI,Wang T,Ansar A,Michael MZ,Van der Hoek M,Haier J,Hussey DJ

更新日期：2014-10-28 00:00:00

abstract：AIM:To highlight the intestinal perforation (IP), an uncommon and catastrophic complication after combined liver-kidney transplantation. METHODS:Combined liver-kidney transplantation (LKTx) with left kidney excision and a cyst fenestration procedure on the right kidney were performed on a case of 46-year-old female wi...

journal_title：World journal of gastroenterology

authors： Peng T,Peng MH,Li LQ,Deng YL,Yang DH,Lu BY,Chen XG,Guo Y,Xiao KY,Chen B,Zhong Q,Wei MY

更新日期：2004-09-15 00:00:00

abstract：AIM:To explore the mode of inheritance of hepatocellular carcinoma (HCC) in a moderately high-incidence area of East China. METHODS:A pedigree survey was conducted in 210 families (3315 individuals) ascertained through 210 HCC probands in Haimen, Jiangsu Province. Simple segregation analysis was conducted using SEGRAN...

journal_title：World journal of gastroenterology

authors： Cai RL,Meng W,Lu HY,Lin WY,Jiang F,Shen FM

更新日期：2003-11-01 00:00:00

abstract：AIM:To elucidate high mobility group-box 3 (HMGB3) protein expression in gastric adenocarcinoma, its potential prognostic relevance, and possible mechanism of action. METHODS:Ninety-two patients with gastric adenocarcinomas surgically removed entered the study. HMGB3 expression was determined by immunohistochemistry t...

journal_title：World journal of gastroenterology

authors： Tang HR,Luo XQ,Xu G,Wang Y,Feng ZJ,Xu H,Shi YW,Zhang Q,Wu LG,Xue CQ,Wang CW,Wu CY

更新日期：2012-12-28 00:00:00

abstract：AIM:To investigate the frequency and timing of post-partum chronic hepatitis B virus (HBV) reactivation and identify its pre-partum predictors. METHODS:Forty-one hepatitis B e antigen (HBeAg)-negative chronic HBV infected pregnant women were prospectively evaluated between the 28th and the 32nd week of gestation. Subj...

journal_title：World journal of gastroenterology

authors： Elefsiniotis I,Vezali E,Vrachatis D,Hatzianastasiou S,Pappas S,Farmakidis G,Vrioni G,Tsakris A

更新日期：2015-01-28 00:00:00

abstract：AIM:To evaluate the clinical significance of oxidative stress markers in patients with hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS:Sixty-four consecutive patients who were admitted to Kagoshima University Medical and Dental Hospital were enrolled in this retrospective study. All patients ha...

journal_title：World journal of gastroenterology

authors： Tamai T,Uto H,Takami Y,Oda K,Saishoji A,Hashiguchi M,Kumagai K,Kure T,Mawatari S,Moriuchi A,Oketani M,Ido A,Tsubouchi H

更新日期：2011-11-28 00:00:00

abstract：AIM:To examine the effect of hepatitis C virus (HCV) structural mimics of regulatory regions of the genome on HCV replication. METHODS:HCV RNA structural mimics were constructed and tested in a HCV genotype 1b aBB7 replicon, and a Japanese fulminant hepatitis-1 (JFH-1) HCV genotype 2a infection model. All sequences we...

journal_title：World journal of gastroenterology

authors： Smolic R,Smolic M,Andorfer JH,Wu CH,Smith RM,Wu GY

更新日期：2010-05-07 00:00:00

abstract：:We present a rare case of a 45-year-old woman who presented with epigastric pain associated with early satiety and weight loss. Imaging revealed a large intra-abdominal mass in the epigastrium. Despite intensive investigations, including ultrasound scanning, computed tomography, upper gastrointestinal endoscopy, and p...

journal_title：World journal of gastroenterology

authors： Chin KF,Khair G,Babu PS,Morgan DR

更新日期：2009-08-14 00:00:00

abstract：:Mesenchymal stem cells (MSC) are cells of stromal origin which exhibit unlimited self-renewal capacity and pluripotency in vitro. It has recently been observed that MSC may also exert a profound immunosuppressive and anti-inflammatory effect both in vitro and in vivo with consequent potential use in autoimmune disorde...

journal_title：World journal of gastroenterology

authors： Taddio A,Tommasini A,Valencic E,Biagi E,Decorti G,De Iudicibus S,Cuzzoni E,Gaipa G,Badolato R,Prandini A,Biondi A,Ventura A

更新日期：2015-04-14 00:00:00