Hepatocellular carcinoma and evidence-based surgery.

abstract：AIM:To evaluate the effect of resveratrol, alone and in combination with fenofibrate, on fructose-induced metabolic genes abnormalities in rats. METHODS:Giving a fructose-enriched diet (FED) to rats for 12 wk was used as a model for inducing hepatic dyslipidemia and insulin resistance. Adult male albino rats (150-200 ...

journal_title：World journal of gastroenterology

authors： Abd El-Haleim EA,Bahgat AK,Saleh S

更新日期：2016-03-14 00:00:00

abstract：AIM:To determine if exacerbation of pre-existing chronic colitis in Winnie (Muc2 mutant) mice induces colonic dysplasia. METHODS:Winnie mice and C57BL6 as a genotype control, were administered 1% w/v dextran sulphate sodium (DSS) orally, followed by drinking water alone in week-long cycles for a total of three cycles....

journal_title：World journal of gastroenterology

authors： Randall-Demllo S,Fernando R,Brain T,Sohal SS,Cook AL,Guven N,Kunde D,Spring K,Eri R

更新日期：2016-10-07 00:00:00

abstract：:Acute pancreatitis (AP) is an acute inflammatory disease of the exocrine pancreas. In Japan, nationwide epidemiological surveys have been conducted every 4 to 5 years by the Research Committee of Intractable Pancreatic Diseases, under the support of the Ministry of Health, Labour, and Welfare of Japan. We reviewed the...

journal_title：World journal of gastroenterology

authors： Hamada S,Masamune A,Shimosegawa T

更新日期：2016-07-28 00:00:00

abstract：:We report a case of duodenal varix bleeding as a long term complication of balloon occluded retrograde transvenous obliteration (BRTO), which was successfully treated with a transjugular intrahepatic portosystemic shunt (TIPS). A 57-year-old man was admitted to the emergency room suffering from melena. He had undergon...

journal_title：World journal of gastroenterology

authors： Kim MJ,Jang BK,Chung WJ,Hwang JS,Kim YH

更新日期：2012-06-14 00:00:00

abstract：AIM:To investigate the effect of intensive vs conventional insulin therapy on perioperative nutritional substrates metabolism in patients undergoing radical distal gastrectomy. METHODS:Within 24 h of intensive care unit management, patients with gastric cancer were enrolled after written informed consent and randomize...

journal_title：World journal of gastroenterology

authors： Liu HC,Zhou YB,Chen D,Niu ZJ,Yu Y

更新日期：2012-06-07 00:00:00

abstract：AIM:To evaluate the association between Chlamydia pneumoniae (Cpn) infection and primary biliary cirrhosis (PBC). METHODS:Cpn IgG and IgM were determined by enzyme-linked immunosorbent assay (ELISA) in 41 well-established PBC patients and two race-matched control groups (post-hepatitis cirrhosis, n = 70; healthy contr...

journal_title：World journal of gastroenterology

authors： Liu HY,Deng AM,Zhang J,Zhou Y,Yao DK,Tu XQ,Fan LY,Zhong RQ

更新日期：2005-07-14 00:00:00

abstract：:Although primary gastrointestinal lymphoma is a rare malignancy, it can cause an intussusception in adults and can be a clinically challenging condition to manage. Intussusception could progress to life-threatening complications if left untreated or could delay chemotherapy if inappropriate surgical management is used...

journal_title：World journal of gastroenterology

authors： Yang TW,Lin YY,Tsuei YW,Chen YL,Huang CY,Hsu SD

更新日期：2016-05-21 00:00:00

abstract：BACKGROUND:The prognosis of gastric cancer continues to remain poor, and epigenetic drugs like histone deacetylase inhibitors (HDACi) have been envisaged as potential therapeutic agents. Nevertheless, clinical trials are facing issues with toxicity and efficacy against solid tumors, which may be partly due to the lack ...

journal_title：World journal of gastroenterology

authors： Amnekar RV,Khan SA,Rashid M,Khade B,Thorat R,Gera P,Shrikhande SV,Smoot DT,Ashktorab H,Gupta S

更新日期：2020-02-14 00:00:00

abstract：:It has since long been known, from everyday experience as well as from animal and human studies, that psychological processes-both affective and cognitive-exert an influence on gastrointestinal sensorimotor function. More specifically, a link between psychological factors and visceral hypersensitivity has been suggest...

journal_title：World journal of gastroenterology

authors： Van Oudenhove L,Coen SJ,Aziz Q

更新日期：2007-07-07 00:00:00

abstract：BACKGROUND:Given the shortage of suitable liver grafts for liver transplantation, proper use of hepatitis B core antibody-positive livers might be a possible way to enlarge the donor pool and to save patients with end-stage liver diseases. However, the safety of hepatitis B virus core antibody positive (HBcAb+) donors ...

journal_title：World journal of gastroenterology

authors： Lei M,Yan LN,Yang JY,Wen TF,Li B,Wang WT,Wu H,Xu MQ,Chen ZY,Wei YG

更新日期：2018-12-28 00:00:00

abstract：AIM:To investigate the efficacy and side effects of the combined therapy of oxaliplatin and capecitabine in patients with metastatic esophageal squamous cell cancer (ESCC) and the survival of the patients. METHODS:Sixty-four patients (median age of 63 years) with histological or cytological confirmation of ESCC receiv...

journal_title：World journal of gastroenterology

authors： Qin TJ,An GL,Zhao XH,Tian F,Li XH,Lian JW,Pan BR,Gu SZ

更新日期：2009-02-21 00:00:00

abstract：:Deficiencies in vitamins or other factors (B6, B12, folic acid, betaine) and genetic disorders for the metabolism of the non-protein amino acid-homocysteine (Hcy) lead to hyperhomocysteinemia (HHcy). HHcy is an integral component of several disorders including cardiovascular disease, neurodegeneration, diabetes and al...

journal_title：World journal of gastroenterology

authors： Ji C,Kaplowitz N

更新日期：2004-06-15 00:00:00

abstract：AIM:To investigate the effect of Chaiqinchengqi decoction (CQCQD) on sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) mRNA expression of pancreatic tissues in acute pancreatitis (AP) rats. METHODS:Thirty Sprague-Dawley (SD) rats were randomized into control group, AP group and CQCQD group (n = 3 x 10). The rats in the ...

journal_title：World journal of gastroenterology

authors： Xue P,Deng LH,Zhang ZD,Yang XN,Xia Q,Xiang DK,Huang L,Wan MH

更新日期：2008-04-21 00:00:00

abstract：:This paper reviews the progress made in understanding the mechanical behaviour of the biliary system. Gallstones and diseases of the biliary tract affect more than 10% of the adult population. The complications of gallstones, i.e. acute pancreatitis and obstructive jandice, can be lethal, and patients with acalculous ...

journal_title：World journal of gastroenterology

authors： Luo X,Li W,Bird N,Chin SB,Hill NA,Johnson AG

更新日期：2007-03-07 00:00:00

abstract：AIM:To examine the calcium metabolism of colorectal cancer (CRC) in patients with colorectal cancer and control patients. METHODS:Seventy newly diagnosed CRC patients were included. The healthy control group was age and gender matched (n=32). Particular attention was devoted to the relationship between serum calcium o...

journal_title：World journal of gastroenterology

authors： Fuszek P,Lakatos P,Tabak A,Papp J,Nagy Z,Takacs I,Horvath HC,Lakatos PL,Speer G

更新日期：2004-07-01 00:00:00

abstract：AIM:To investigate the expression and clinical significance of B7 homolog 3 (B7-H3) and β-1,3-galactosyltransferase-4 (B3GALT4) in colorectal cancer (CRC) patients. METHODS:Using tissue microarray, we identified the expression of B7-H3 and B3GALT4 in 223 CRC patient samples by immunohistochemistry and evaluated the po...

journal_title：World journal of gastroenterology

authors： Zhang T,Wang F,Wu JY,Qiu ZC,Wang Y,Liu F,Ge XS,Qi XW,Mao Y,Hua D

更新日期：2018-08-21 00:00:00

abstract：AIM:To investigate the value of ultrasound elastography combined with serological indexes in diagnosing liver fibrosis and assessing its severity. METHODS:A total of 338 chronic hepatitis B (CHB) patients were divided into a disease group (patients with hepatic fibrosis) and control group (subjects without hepatic fib...

journal_title：World journal of gastroenterology

authors： Xu B,Zhou NM,Cao WT,Li XJ

更新日期：2018-10-07 00:00:00

abstract：:Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions are well established biological events which have an important role in not just normal tissue and organ development, but in the pathogenesis of diseases. Increasing evidence has established their presence in the human colon during colorectal carcinoge...

journal_title：World journal of gastroenterology

authors： Sipos F,Galamb O

更新日期：2012-02-21 00:00:00

abstract：AIM:To investigate whether octreotide can inhibit the growth of human gallbladder cancer cells in vitro and to elucidate the antineoplastic mechanism of octreotide in gallbladder cancer. METHODS:A human gallbladder cancer cell line, GBC-SD, was cultured in vitro. The antiproliferative effects of octreotide were examin...

journal_title：World journal of gastroenterology

authors： Wang JH,Xing QT,Yuan MB

更新日期：2004-04-01 00:00:00

abstract：AIM:To clarify the role of serum anti-Helicobacter pylori (H. pylori) antibody titers in gastric cancer. METHODS:In this cross-sectional study, the effect of patients' baseline characteristics and endoscopic findings on their serum antibody titers were assessed. We evaluated consecutive patients who underwent esophago...

journal_title：World journal of gastroenterology

authors： Toyoshima O,Nishizawa T,Sakitani K,Yamakawa T,Takahashi Y,Yamamichi N,Hata K,Seto Y,Koike K,Watanabe H,Suzuki H

更新日期：2018-09-21 00:00:00

abstract：AIM:To study the influence of redox environment of Escherichia coli (E. coli) cytoplasm on disulfide bond formation of recombinant proteins. METHODS:Bovine fibroblast growth factor (BbFGF) was selected as a model of simple proteins with a single disulfide bond and free cysteines. Anti-HBsAg single-chain Fv (HBscFv), a...

journal_title：World journal of gastroenterology

authors： Xiong S,Wang YF,Ren XR,Li B,Zhang MY,Luo Y,Zhang L,Xie QL,Su KY

更新日期：2005-02-21 00:00:00

abstract：:Carcinoids are tumors derived from neuroendocrine cells and often produce functional peptide hormones. Approximately 54.5% arise in the gastrointestinal tract and frequently metastasize to the liver. Primary hepatic carcinoid tumors (PHCT) are extremely rare; only 95 cases have been reported. A 65-year-old man came to...

journal_title：World journal of gastroenterology

authors： Fenoglio LM,Severini S,Ferrigno D,Gollè G,Serraino C,Bracco C,Castagna E,Brignone C,Pomero F,Migliore E,David E,Salizzoni M

更新日期：2009-05-21 00:00:00

abstract：AIM:To determine the efficacy and safety of meticulous cannulation by needle-knife. METHODS:Three needle-knife procedures were used to facilitate cannulation in cases when standard cannulation techniques failed. A total of 104 cannulations via the minor papilla attempted in 74 patients at our center between January 20...

journal_title：World journal of gastroenterology

authors： Wang W,Gong B,Jiang WS,Liu L,Bielike K,Xv B,Wu YL

更新日期：2015-05-21 00:00:00

abstract：AIM:To investigate the existence and clinical significance of hepatitis C virus (HCV) RNA in the serum and peripheral blood mononuclear cells (PBMC) of patients with hepatitis C. METHODS:HCV RNA was detected by nested polymerase chain reaction (Nested PCR) in serum and in PBMC of 46 patients with acute hepatitis C (AH...

journal_title：World journal of gastroenterology

authors： Zhou P,Cai Q,Chen YC,Zhang MS,Guan J,Li XJ

更新日期：1997-06-15 00:00:00

abstract：AIM:To summarise the literature data on hepatitis C virus (HCV)-infected patients concerning the prevalence of glucose abnormalities and associated risk. METHODS:We conducted a PubMed search and selected all studies found with the key words "HCV" or "hepatitis C virus" and "diabetes" or "insulin resistance". We includ...

journal_title：World journal of gastroenterology

authors： Desbois AC,Cacoub P

更新日期：2017-03-07 00:00:00

abstract：:The term "hemangioma" refers to the common tumor of infancy that exhibits rapid postnatal growth and slow regression during childhood. It may cause confusion with venous malformations that are often incorrectly called "cavernous hemangioma". Venous malformations comprise abnormally formed channels that are lined by qu...

journal_title：World journal of gastroenterology

authors： Fernandez-Pineda I

更新日期：2009-11-07 00:00:00

abstract：AIM:Overexpression of tumor protein p53-induced nuclear protein 1 (TP53INP1) induces G1 cell cycle arrest and increases p53-mediated apoptosis. To clarify the clinical importance of TP53INP1, we analyzed TP53INP1 and p53 expression in gastric cancer. METHODS:TP53INP1 and p53 expression were examined using immunohistoc...

journal_title：World journal of gastroenterology

authors： Jiang PH,Motoo Y,Garcia S,Iovanna JL,Pébusque MJ,Sawabu N

更新日期：2006-02-07 00:00:00

abstract：AIM:To investigate the expression of programmed death (PD)-1, PD ligand 1 (PD-L1) and PD-L2 in liver tissues in the context of chronic hepatitis and hepatocellular carcinoma (HCC). METHODS:Liver biopsies and HCC specimens from patients were collected and histologically examined. The expression of PD-1, PD-L1, and PD-L...

journal_title：World journal of gastroenterology

authors： Wang BJ,Bao JJ,Wang JZ,Wang Y,Jiang M,Xing MY,Zhang WG,Qi JY,Roggendorf M,Lu MJ,Yang DL

更新日期：2011-07-28 00:00:00

abstract：:Recently, inflammatory bowel disease (IBD) has been the subject of considerable research, with increasing attention being paid to the loss of intestinal epithelial cell barrier function as a mechanism of pathogenesis. Ste20-related proline/alanine-rich kinase (SPAK) is involved in regulating barrier function. SPAK is ...

journal_title：World journal of gastroenterology

authors： Yan Y,Merlin D

更新日期：2008-10-28 00:00:00

abstract：:In a recently published letter to the editor, we debated the proposal by Coccolini et al to treat gastrointestinal stromal tumors (GISTs) of the esophagogastric junction with enucleation and, if indicated, adjuvant therapy. We highlighted that, because the prognostic impact of a T1 high-mitotic rate esophageal GIST is...

journal_title：World journal of gastroenterology

authors： Peparini N,Chirletti P

更新日期：2013-03-28 00:00:00