Hyperhomocysteinemia, endoplasmic reticulum stress, and alcoholic liver injury.

abstract：:A liver tumor 35 mm in diameter was found incidentally in a 40-year-old woman who had no history of liver diseases or the use of oral contraceptives. Radiological diagnostics showed the typical findings of liver cell adenoma (LCA). Dynamic computed tomography revealed that the tumor showed a homogenous enhancement in ...

journal_title：World journal of gastroenterology

authors： Kogure T,Ueno Y,Sekiguchi S,Ishida K,Igarashi T,Wakui Y,Iwasaki T,Shimosegawa T

更新日期：2009-03-14 00:00:00

abstract：:Constitutive activation of the insulin-like growth factor (IGF)-signaling axis is frequently observed in human hepatocellular carcinoma (HCC). Especially the overexpression of the fetal growth factor IGF-II, IGF-I receptor (IGF-IR), and cytoplasmic downstream effectors such as insulin-receptor substrates (IRS) contrib...

journal_title：World journal of gastroenterology

authors： Breuhahn K,Schirmacher P

更新日期：2008-03-21 00:00:00

abstract：:AIM:To prepare valaciclovir polybutylcyan_oacrylate nanoparticles (VACV-PBCA-NP) with liver targeting and hepatocyte permeable charateristics.METHODS: Emulsion polymerization method was employed to prepare VACV-PBCA-NP.The formula and preparation conditions were optimized by using the uniform design. The organ distrib...

journal_title：World journal of gastroenterology

authors： Zhang ZR,He Q

更新日期：1999-08-01 00:00:00

abstract：AIM:To investigate the effects of herbal compound 861 (Cpd 861) on cell proliferation in human hepatic stellate cells (LX-2) and human hepatocellular liver carcinoma cells (HepG2), and expression of alpha-smooth muscle actin (alpha-SMA) in LX-2 cells. METHODS:LX-2 and HepG2 cells were incubated with various concentrat...

journal_title：World journal of gastroenterology

authors： Wang L,Wang J,Wang BE,Xiao PG,Qiao YJ,Tan XH

更新日期：2004-10-01 00:00:00

abstract：AIM:To investigate the effects of gastric pacing on gastric emptying and plasma motilin level in a canine model of gastric motility disorders and the correlation between gastric emptying and plasma motilin level. METHODS:Ten healthy Mongrel dogs were divided into: experimental group of six dogs and control group of fo...

journal_title：World journal of gastroenterology

authors： Yang M,Fang DC,Li QW,Sun NX,Long QL,Sui JF,Gan L

更新日期：2004-02-01 00:00:00

abstract：AIM:To analyze the effects of premedication with Pronase for endoscopic ultrasound (EUS) examination of the stomach. METHODS:This was a prospective, randomized and controlled clinical study. All patients were randomly assigned to either the Pronase group or placebo group. The pretreatment solution was a mixed solution...

journal_title：World journal of gastroenterology

authors： Wang GX,Liu X,Wang S,Ge N,Guo JT,Sun SY

更新日期：2016-12-28 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) can affect the entire gastrointestinal tract. Proximal small bowel (SB) lesions are associated with a significant risk of stricturing disease and multiple abdominal surgeries. The assessment of SB in patients with CD is therefore necessary because it may have a significant impact on prog...

journal_title：World journal of gastroenterology

authors： Le Berre C,Trang-Poisson C,Bourreille A

更新日期：2019-08-21 00:00:00

abstract：AIM:To assess the incidence and analyze the risk factors for Clostridium difficile-associated diarrhea (CDAD) after living donor liver transplantation (LDLT) in adult. METHODS:The microbiological data and medical records of 242 adult recipients that underwent LDLT at the Tokyo University Hospital were analyzed retrosp...

journal_title：World journal of gastroenterology

authors： Hashimoto M,Sugawara Y,Tamura S,Kaneko J,Matsui Y,Togashi J,Makuuch M

更新日期：2007-04-14 00:00:00

abstract：AIM:To investigate the effect of integrin-linked kinase (ILK) on proliferation, metastasis, and invasion of the colorectal cancer cell line SW480. METHODS:In this study, the colorectal cancer cell line SW480 was stably transfected with ILK plasmids, and small interfering RNA (siRNA) was used to knockdown expression of...

journal_title：World journal of gastroenterology

authors： Shen H,Ma JL,Zhang Y,Deng GL,Qu YL,Wu XL,He JX,Zhang S,Zeng S

更新日期：2016-04-21 00:00:00

abstract：:This review updates the current views on aging gastric mucosa and the mechanisms of its increased susceptibility to injury. Experimental and clinical studies indicate that gastric mucosa of aging individuals-"aging gastropathy"-has prominent structural and functional abnormalities vs young gastric mucosa. Some of thes...

journal_title：World journal of gastroenterology

authors： Tarnawski AS,Ahluwalia A,Jones MK

更新日期：2014-04-28 00:00:00

abstract：AIM:To investigate microRNA-133a (miR-133a) expression in colorectal cancer (CRC) and its relationship with tumorigenesis and disease prognosis. METHODS:Quantitative real-time polymerase chain reaction was used to measure levels of miR-133a in tumor samples and adjacent non-cancerous tissues from 169 patients undergoi...

journal_title：World journal of gastroenterology

authors： Wang LL,Du LT,Li J,Liu YM,Qu AL,Yang YM,Zhang X,Zheng GX,Wang CX

更新日期：2014-08-28 00:00:00

abstract：AIM:To determine serum vitamin D levels and colonic vitamin D receptor (VDR) expression in inflammatory bowel disease (IBD) and non-IBD patients and correlate these with histopathology. METHODS:Puerto Rican IBD (n = 10) and non-IBD (n = 10) patients ≥ 21 years old scheduled for colonoscopy were recruited. Each patient...

journal_title：World journal of gastroenterology

authors： Abreu-Delgado Y,Isidro RA,Torres EA,González A,Cruz ML,Isidro AA,González-Keelan CI,Medero P,Appleyard CB

更新日期：2016-04-07 00:00:00

abstract：AIM:To characterize the protein files in blood from same patients with esophageal squamous cell carcinoma (ESCC) before and after operation at the high-incidence area for ESCC in Henan Province, China. METHODS:Two-dimensional electrophoresis, silver staining and ImageMaster 2-DE analysis software were applied to the d...

journal_title：World journal of gastroenterology

authors： An JY,Fan ZM,Zhuang ZH,Qin YR,Gao SS,Li JL,Wang LD

更新日期：2004-11-15 00:00:00

abstract：AIM:To determine the expression of c-fos in gastric myenteric plexus and spinal cord of rats with cervical spondylosis and its clinical significance. METHODS:A cervical spondylosis model was established in rats by destroying the stability of cervical posterior column, and the cord segments C(4-6) and gastric antrum we...

journal_title：World journal of gastroenterology

authors： Song PS,Kong KM,Niu CY,Qi WL,Wu LF,Wang XJ,Han W,Huang K,Chen ZF

更新日期：2005-01-28 00:00:00

abstract：AIM:To assess intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) for monitoring early efficacy of chemotherapy in a human gastric cancer mouse model. METHODS:IVIM-DWI was performed with 12 b-values (0-800 s/mm(2)) in 25 human gastric cancer-bearing nude mice at baseline (day 0), and then they were rand...

journal_title：World journal of gastroenterology

authors： Song XL,Kang HK,Jeong GW,Ahn KY,Jeong YY,Kang YJ,Cho HJ,Moon CM

更新日期：2016-06-28 00:00:00

abstract：AIM:To identify whether chitinase 3-like 1 (CHI3L1) serves as a suitable biomarker for the prognosis of esophageal squamous cell carcinoma (ESCC) and to analyze this protein's cellular source. METHODS:An ELISA was conducted to detect the concentration of CHI3L1 in the serum of 150 ESCC patients diagnosed between Janua...

journal_title：World journal of gastroenterology

authors： Xing S,Zheng X,Zeng T,Zeng MS,Zhong Q,Cao YS,Pan KL,Wei C,Hou F,Liu WL

更新日期：2017-11-21 00:00:00

abstract：AIM:To investigate the effect of Danzhijiangtang capsule (DJC) on monocyte chemoattractant protein-1 (MCP-1) mRNA expression in newly diagnosed type 2 diabetes mellitus (T2DM) subclinical vascular lesions. METHODS:Sixty-two patients with newly diagnosed T2DM subclinical vascular lesions were randomly divided into a co...

journal_title：World journal of gastroenterology

authors： Fang ZH,Liu Y,Bao TT,Ni YQ,Liu J,Shi GB,Wu JP,Yang JP,Zhang H

更新日期：2013-05-21 00:00:00

abstract：:The intestinal microbiome is a dynamic system of interactions between the host and its microbes. Under physiological conditions, a fine balance and mutually beneficial relationship is present. Disruption of this balance is a hallmark of inflammatory bowel disease (IBD). Whether an altered microbiome is the consequence...

journal_title：World journal of gastroenterology

authors： Babickova J,Gardlik R

更新日期：2015-10-28 00:00:00

abstract：AIM:To identify factors associated with the age at onset of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS:Five hundred and fifty-six consecutive patients positive for HCV antibody and treatment-naïve HCC diagnosed between 1995 and 2004 were analyzed. Patients were classified into three groups...

journal_title：World journal of gastroenterology

authors： Akiyama T,Mizuta T,Kawazoe S,Eguchi Y,Kawaguchi Y,Takahashi H,Ozaki I,Fujimoto K

更新日期：2011-02-21 00:00:00

abstract：BACKGROUND:Acute liver failure (ALF) is a significant and complex hepatic insult that may rapidly progress to life-threatening conditions. Recently, menstrual blood stem cells (MenSCs) have been identified as a group of easily accessible mesenchymal stem cells with the advantages of non-invasive acquisition, low immuno...

journal_title：World journal of gastroenterology

authors： Cen PP,Fan LX,Wang J,Chen JJ,Li LJ

更新日期：2019-11-07 00:00:00

abstract：AIM:To observe the therapeutic effects of dexamethasone on rats with severe acute pancreatitis (SAP) and investigate the influences of dexamethasone on the inflammatory mediators and NF-kappaB expression in multiple organs of SAP rats as well as the mechanisms involved. METHODS:Ninety Sprague-Dawley (SD) rats with SAP...

journal_title：World journal of gastroenterology

authors： Zhang XP,Zhang L,Chen LJ,Cheng QH,Wang JM,Cai W,Shen HP,Cai J

更新日期：2007-01-28 00:00:00

abstract：AIM:To evaluate of scoring system in predicting choledocholithiasis in selective intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC). METHODS:The scoring system of predicting choledocholithiasis was developed during the retrospective study in 264 cases, and was tested in 184 to evaluate its p...

journal_title：World journal of gastroenterology

authors： Sun XD,Cai XY,Li JD,Cai XJ,Mu YP,Wu JM

更新日期：2003-04-01 00:00:00

abstract：:The motor function of the gastrointestinal tract has primarily been studied using manometry and radiography, though more indirect tests have also been applied. Manometry and radiography do not provide detailed information about the muscle properties as can be assessed from studies of muscle properties in muscle strips...

journal_title：World journal of gastroenterology

authors： Gregersen H,Liao D

更新日期：2006-05-14 00:00:00

abstract：AIM:To assess the incidence and risk factors associated with colonic perforation due to colonoscopy. METHODS:This was a retrospective cross-sectional study. Patients were retrospectively eligible for inclusion if they were 18 years and older and had an inpatient or outpatient colonoscopy procedure code in any facility...

journal_title：World journal of gastroenterology

authors： Hamdani U,Naeem R,Haider F,Bansal P,Komar M,Diehl DL,Kirchner HL

更新日期：2013-06-21 00:00:00

abstract：:The technique of endoscopic submucosal dissection (ESD), which was developed for en bloc resection of large lesions in the stomach, has been widely accepted for the treatment of the entire gastrointestinal tract. Many minimally invasive endoscopic therapies based on ESD have been developed recently. Endoscopic submuco...

journal_title：World journal of gastroenterology

authors： Zhou PH,Shi Q,Zhong YS,Yao LQ

更新日期：2013-11-07 00:00:00

abstract：AIM:To evaluate the effects of ethanol on the insulin-like growth factor-I (IGF-I) system involved in c-Jun N-terminal kinase (JNK1/2) and alcoholdehydrogenase (ADH) activity in primary cultured rat hepatocytes. METHODS:Hepatocytes isolated from male Sprague-Dawley rats were incubated with various concentrations of et...

journal_title：World journal of gastroenterology

authors： Oh YI,Kim JH,Kang CW

更新日期：2008-07-21 00:00:00

abstract：:Hepatobiliary cystadenomas are rare tumors that are difficult to diagnose preoperatively. They can reach large sizes that make them real intraoperative "surprises". A 63-year-old woman, presented with a symptomatic huge abdominal cystic mass, underwent complete resection of the mass with safety margins. Histopathologi...

journal_title：World journal of gastroenterology

authors： Beuran M,Venter MD,Dumitru L

更新日期：2006-06-21 00:00:00

abstract：:The pancreatic manifestations seen in patients with von Hippel-Lindau (VHL) disease are subdivided into 2 categories: pancreatic neuroendocrine tumors (NET), and cystic lesions, including simple cyst and serous cystadenoma. The VHL-associated cystic lesions are generally asymptomatic and do not require any treatment, ...

journal_title：World journal of gastroenterology

authors： Tamura K,Nishimori I,Ito T,Yamasaki I,Igarashi H,Shuin T

更新日期：2010-09-28 00:00:00

abstract：:Gastrin is the main hormone responsible for the stimulation of gastric acid secretion; in addition, gastrin and its derivatives exert proliferative and antiapoptotic effects on several cell types. Gastrin synthesis and secretion are increased in certain situations, for example, when proton pump inhibitors are used. Th...

journal_title：World journal of gastroenterology

authors： Chueca E,Lanas A,Piazuelo E

更新日期：2012-12-07 00:00:00

abstract：:AIM:To investigate the incidence and management of nutritional deficiencies following a gastrectomy.METHODS:A gastrectomy population of 227 patients in London was followed up for 30 years after operation to detect and treat nutritional deficiencies.RESULTS:By the end of the first decade iron deficiency was the commone...

journal_title：World journal of gastroenterology

authors： Tovey FI,Hobsley M

更新日期：2000-02-01 00:00:00