Reactivation of the insulin-like growth factor-II signaling pathway in human hepatocellular carcinoma.

abstract：:Biliary duct injuries are frequently iatrogenic, being associated with surgery for gallbladder stones. However, blunt abdominal trauma such as a motor vehicle crash is a rare cause of extrahepatic biliary stricture. A few reports have been published on biliary strictures treated with endoscopic therapy. In the present...

journal_title：World journal of gastroenterology

authors： Kang DO,Kim TH,You SS,Min HJ,Kim HJ,Jung WT,Lee OJ

更新日期：2008-04-14 00:00:00

abstract：AIM:To compare natural orifice transluminal endoscopic surgery (NOTES) vs standard laparoscopic ovariectomy in mini pigs with respect to technical aspects, complications and parameters of systemic inflammatory response. METHODS:This was a randomized, experimental, survival study. Ten female mini pigs underwent NOTES t...

journal_title：World journal of gastroenterology

authors： Martínek J,Ryska O,Filípková T,Doležel R,Juhas S,Motlík J,Holubová M,Nosek V,Rotnáglová B,Zavoral M,Ryska M

更新日期：2012-07-21 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the second most common cause of cancer death worldwide. It is broadly described that cyclooxygenase-2 (COX-2) is mainly overexpressed in CRC but less is known regarding post-translational modifications of this enzyme that may regulate its activity, intracellular localization and st...

journal_title：World journal of gastroenterology

authors： Prieto P,Jaén RI,Calle D,Gómez-Serrano M,Núñez E,Fernández-Velasco M,Martín-Sanz P,Alonso S,Vázquez J,Cerdán S,Peinado MÁ,Boscá L

更新日期：2019-01-28 00:00:00

abstract：:Surgical resection offers the best opportunity for survival in patients with colorectal cancer metastatic to the liver, with five-year survival rates up to 58% in selected cases. However, only a minority are resectable at the time of diagnosis. Continuous research in this field aims at increasing the percentage of pat...

journal_title：World journal of gastroenterology

authors： Misiakos EP,Karidis NP,Kouraklis G

更新日期：2011-09-28 00:00:00

abstract：AIM:To test the hypothesis that enhancement of the activity of heme oxygenase can interfere with processes of fibrogenesis associated with recurrent liver injury, we investigated the therapeutic potential of over-expression of heme oxygense-1 in a CCl(4)-induced micronodular cirrhosis model. METHODS:Recombinant adeno-...

journal_title：World journal of gastroenterology

authors： Tsui TY,Lau CK,Ma J,Glockzin G,Obed A,Schlitt HJ,Fan ST

更新日期：2006-04-07 00:00:00

abstract：AIM:To evaluate the effects of extrahepatic collaterals to the liver on liver damage and patient outcome after embolotherapy for the ruptured hepatic artery pseudoaneurysm following hepatobiliary pancreatic surgery. METHODS:We reviewed 9 patients who underwent transcatheter arterial embolization (TAE) for the ruptured...

journal_title：World journal of gastroenterology

authors： Tajima Y,Kuroki T,Tsutsumi R,Sakamoto I,Uetani M,Kanematsu T

更新日期：2007-01-21 00:00:00

abstract：AIM:To evaluate the influence of avidin chase on the side effects of radioimmunotherapy (RIT) in nude mice bearing human colon carcinoma and therapeutic outcome. METHODS:Purified anti-CEA monoclonal antibody (McAb) was biotinylated with NHS-biotin, and then radiolabeled with 188Re by the direct method. 188Re-labeled b...

journal_title：World journal of gastroenterology

authors： Li GP,Wang YX,Huang K,Zhang H,Zhang CF

更新日期：2005-04-07 00:00:00

abstract：AIM:To investigate the association between the tag single nucleotide polymorphisms (TagSNPs) of NOD1 and NOD2 and the risk of developing gastric cancer. METHODS:We conducted a hospital-based case-control study including 296 incident gastric cancer patients and 160 gastritis controls. Eight TagSNPs in the NOD1 and NOD2...

journal_title：World journal of gastroenterology

authors： Wang P,Zhang L,Jiang JM,Ma D,Tao HX,Yuan SL,Wang YC,Wang LC,Liang H,Zhang ZS,Liu CJ

更新日期：2012-05-07 00:00:00

abstract：AIM:To investigate the expression of the transforming growth factor beta 1(TGF-beta 1) mRNA in different stages of alcoholic liver disease (ALD) and its clinical value. METHODS:One hundred and seven male alcoholics were grouped by clinical findings into four groups: alcohol abusers without liver impairment (n =22), al...

journal_title：World journal of gastroenterology

authors： Chen WX,Li YM,Yu CH,Cai WM,Zheng M,Chen F

更新日期：2002-04-01 00:00:00

abstract：:Intestinal lymphangiectasia, characterized by dilatation of intestinal lacteals, is rare. The major treatment for primary intestinal lymphangiectasia is dietary modification. Surgery to relieve symptoms and to clarify the etiology should be considered when medical treatment failed. This article reports a 49-year-old w...

journal_title：World journal of gastroenterology

authors： Chen CP,Chao Y,Li CP,Lo WC,Wu CW,Tsay SH,Lee RC,Chang FY

更新日期：2003-12-01 00:00:00

abstract：AIM:As the conventional combined liver-small bowel transplantation is complicated with many postoperative complications, the aim of this study was to describe a modified technique for the combined liver-small bowel transplantation with preservation of the duodenum, partial head of pancreas and hepatic biliary system in...

journal_title：World journal of gastroenterology

authors： Yin ZY,Ni XD,Jiang F,Li N,Li YS,Li JS

更新日期：2003-07-01 00:00:00

abstract：AIM:To examine the role of microRNA 1181 (miR-1181) in invasion and proliferation in pancreatic cancer. METHODS:We analyzed the expression of miR-1181 in several pancreatic cancer cell lines and generated stable MIA-PaCa-2 and PANC-1 cell lines with up-regulated miR-1181 expression using an adenovirus delivery system....

journal_title：World journal of gastroenterology

authors： Wang J,Guo XJ,Ding YM,Jiang JX

更新日期：2017-03-07 00:00:00

abstract：AIM:To investigate the relationship between the expression of p16 gene and the gastric carcinogenesis, depth of invasion and lymph node metastases, and to evaluate the deletion and mutation of exon 2 in p16 gene in gastric carcinoma. METHODS:The expression of p16 protein was examined by streptavidin-peroxidase conjuga...

journal_title：World journal of gastroenterology

authors： He XS,Su Q,Chen ZC,He XT,Long ZF,Ling H,Zhang LR

更新日期：2001-08-01 00:00:00

abstract：AIM:To review the surgical outcomes in terms of the surgical indications and relevant prognostic factors. METHODS:Sixteen patients underwent therapeutic lung surgery between March 1999 and May 2006. The observation period was terminated on May 31, 2007. The surgical outcomes and the clinicopathological factors were co...

journal_title：World journal of gastroenterology

authors： Kwon JB,Park K,Kim YD,Seo JH,Moon SW,Cho DG,Kim YW,Kim DG,Yoon SK,Lim HW

更新日期：2008-10-07 00:00:00

abstract：AIM:To investigate the therapeutic effects of recombinant human growth hormone (rhGH) on rat septic shock with intraabdominal infection by E. coli and its possible mechanism. METHODS:76 SD rats were divided into 3 groups randomly: control group (group C, n=16) without any special treatment, septic shock group (group S...

journal_title：World journal of gastroenterology

authors： Huang Y,Wang SR,Yi C,Ying MY,Lin Y,Zhi MH

更新日期：2002-12-01 00:00:00

abstract：AIM:To evaluate whether FDG-positron emission tomography (PET)/computed tomography (CT) may be an accurate technique in the assessment of the T stage in patients with colorectal cancer. METHODS:Thirty four consecutive patients (20 men and 14 women; mean age: 63 years) with a histologically proven diagnosis of colorect...

journal_title：World journal of gastroenterology

authors： Mainenti PP,Iodice D,Segreto S,Storto G,Magliulo M,De Palma GD,Salvatore M,Pace L

更新日期：2011-03-21 00:00:00

abstract：AIM:To explore recent trends, modes of diagnosis, ethnic distribution and the mortality to incidence ratio of primary liver cancer by subtypes in England and Wales. METHODS:We obtained incidence (1979-2008) and mortality (1968-2008) data for primary liver cancer for England and Wales and calculated age-standardised in...

journal_title：World journal of gastroenterology

authors： Ladep NG,Khan SA,Crossey MM,Thillainayagam AV,Taylor-Robinson SD,Toledano MB

更新日期：2014-02-14 00:00:00

abstract：AIM:Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS:Thirty lesions each of hyperdense, isodense and hypodense attenua...

journal_title：World journal of gastroenterology

authors： Veit P,Kuehle C,Beyer T,Kuehl H,Bockisch A,Antoch G

更新日期：2006-04-21 00:00:00

abstract：AIM:To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS:A retrospective review of the medical records of 55 patients diagnosed with cholangio-carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to de...

journal_title：World journal of gastroenterology

authors： Farhat MH,Shamseddine AI,Tawil AN,Berjawi G,Sidani C,Shamseddeen W,Barada KA

更新日期：2008-05-28 00:00:00

abstract：AIM:To investigate GATA5, SFRP2, and ITGA4 methylation in plasma DNA as noninvasive biomarkers for colorectal cancer (CRC) or adenomas. METHODS:There were 57 CRC patients, 30 adenomas patients, and 47 control patients enrolled in this study. Methylation-specific polymerase chain reaction was used to determine the prom...

journal_title：World journal of gastroenterology

authors： Zhang X,Song YF,Lu HN,Wang DP,Zhang XS,Huang SL,Sun BL,Huang ZG

更新日期：2015-03-07 00:00:00

abstract：:Clostridium difficile (CD), specifically its toxins, have been implicated as a risk factor for exacerbation of the inflammatory process in up to 5% of patients with ulcerative colitis or Crohnos disease. Typical evidence of colonic changes with CD infection, including pseudomembranous exudate, are often not present; h...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2008-05-14 00:00:00

abstract：AIM:To investigate biogenesis and intracellular localizations of clusterin to elucidate the potential molecular mechanisms implicated in tumorigenesis of esophageal mucosa. METHODS:Semi-quantitative RT-PCR for multi-region alteration analysis, Western blot for different transcriptional forms and immunohistochemical st...

journal_title：World journal of gastroenterology

authors： He HZ,Song ZM,Wang K,Teng LH,Liu F,Mao YS,Lu N,Zhang SZ,Wu M,Zhao XH

更新日期：2004-05-15 00:00:00

abstract：AIM:To better understand the clinical significance of hepatitis B serologic markers in babies born to hepatitis B surface antigen (HBsAg) positive mothers, the incidence of maternal serologic markers of hepatitis B via placenta and its transformation in these babies were investigated. METHODS:Mothers with positive HBs...

journal_title：World journal of gastroenterology

authors： Wang JS,Chen H,Zhu QR

更新日期：2005-06-21 00:00:00

abstract：:Colorectal cancer is a major public health burden worldwide. There is clear-cut evidence that screening will reduce colorectal cancer mortality and the only contentious issue is which screening tool to use. Most evidence points towards screening with fecal occult blood testing. The immunochemical fecal occult blood te...

journal_title：World journal of gastroenterology

authors： McLoughlin RM,O'Morain CA

更新日期：2006-11-14 00:00:00

abstract：:Despite progress in the treatment of advanced and metastatic pancreatic cancer (PC), the outcome of this disease remains dismal for the majority of patients. Given the moderate efficacy of treatment, prognostic factors may help to guide treatment decisions. Several trials identified baseline performance status as an i...

journal_title：World journal of gastroenterology

authors： Boeck S,Hinke A,Wilkowski R,Heinemann V

更新日期：2007-01-14 00:00:00

abstract：:The normal esophageal mucosa creates a protective epithelial barrier that constrains the acidic reflux in the esophageal lumen. Microscopic findings and functional studies indicate that this barrier might be impaired in patients with non erosive reflux disease (NERD) but not in patients with functional heartburn (FH)....

journal_title：World journal of gastroenterology

authors： Triantos C,Koukias N,Karamanolis G,Thomopoulos K

更新日期：2015-05-21 00:00:00

abstract：AIM:Quasispecies of hepatitis C virus (HCV) are the foundation for rapid sequence evolution of HCV to evade immune surveillance of hosts. The consensus sequence evolution of a segment of HCV NS3 region, which encompasses putative cytotoxic T cell epitopes, was evaluated. METHODS:Three male patients, infected with HCV ...

journal_title：World journal of gastroenterology

authors： Guo HZ,Yin Y,Wang WL,Zhang CS,Wang T,Wang Z,Zhang J,Cheng H,Wang HT

更新日期：2004-03-15 00:00:00

abstract：AIM:To investigate retrospectively the long-term effect of endoscopic sphincterotomy (ES) including exocrine pancreatic function in patients with stenosis of ampulla of Vater. METHODS:After diagnostic endoscopic retrograde cholangiopancreatography (ERCP) and ES because of stenosis of the ampulla of Vater (SOD Type I),...

journal_title：World journal of gastroenterology

authors： Ewald N,Marzeion AM,Bretzel RG,Kloer HU,Hardt PD

更新日期：2007-02-14 00:00:00

abstract：AIM:To examine an increased risk of esophageal adenocarcinoma is restricted to patients who develop Barrett's esophagus or whether esophagitis per se is a risk factor for adenocarcinoma. METHODS:A population-based cohort of patients with histological evidence of esophagitis without Barrett's esophagus was constructed ...

journal_title：World journal of gastroenterology

authors： Murphy SJ,Anderson LA,Johnston BT,Fitzpatrick DA,Watson PR,Monaghan P,Murray LJ

更新日期：2005-12-14 00:00:00

abstract：AIM:To determine the incidence of human epidermal growth factor receptor 2 (HER2) over expression in oesophageal cancers. METHODS:A retrospective study, of one hundred consecutive cases of endoscopic histological samples of oesophageal cancers from a single British cancer network were included. Cancer cases were diagn...

journal_title：World journal of gastroenterology

authors： Al-Momani H,Barnes R,El-Hadi A,Shah R,Lewis WG,Edwards P

更新日期：2012-11-28 00:00:00