Colorectal cancer screening.

Abstract:

:Colorectal cancer is a major public health burden worldwide. There is clear-cut evidence that screening will reduce colorectal cancer mortality and the only contentious issue is which screening tool to use. Most evidence points towards screening with fecal occult blood testing. The immunochemical fecal occult blood tests have a higher sensitivity than the guaiac-based tests. In addition, their automation and haemoglobin quantification allows a threshold for colonoscopy to be selected that can be accommodated within individual health care systems.

journal_name

World J Gastroenterol

authors

McLoughlin RM,O'Morain CA

doi

10.3748/wjg.v12.i42.6747

subject

Has Abstract

pub_date

2006-11-14 00:00:00

pages

6747-50

issue

42

eissn

1007-9327

issn

2219-2840

journal_volume

12

pub_type

社论,评审
  • Factors that mediate colonization of the human stomach by Helicobacter pylori.

    abstract::Helicobacter pylori (H. pylori) colonizes the stomach of humans and causes chronic infection. The majority of bacteria live in the mucus layer overlying the gastric epithelial cells and only a small proportion of bacteria are found interacting with the epithelial cells. The bacteria living in the gastric mucus may act...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i19.5610

    authors: Dunne C,Dolan B,Clyne M

    更新日期:2014-05-21 00:00:00

  • Evaluation of endoscopic biliary stenting for obstructive jaundice caused by hepatocellular carcinoma.

    abstract:AIM:To review the usefulness of endoscopic biliary stenting for obstructive jaundice caused by hepatocellular carcinoma and identify problems that may need to be addressed. METHODS:The study population consisted of 36 patients with obstructive jaundice caused by hepatocellular carcinoma (HCC) who underwent endoscopic ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i22.6968

    authors: Sugiyama G,Okabe Y,Ishida Y,Saitou F,Kawahara R,Ishikawa H,Horiuchi H,Kinoshita H,Tsuruta O,Sata M

    更新日期:2014-06-14 00:00:00

  • Molecular mechanisms of liver preconditioning.

    abstract::Ischemia/reperfusion (I/R) injury still represents an important cause of morbidity following hepatic surgery and limits the use of marginal livers in hepatic transplantation. Transient blood flow interruption followed by reperfusion protects tissues against damage induced by subsequent I/R. This process known as ische...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v16.i48.6058

    authors: Alchera E,Dal Ponte C,Imarisio C,Albano E,Carini R

    更新日期:2010-12-28 00:00:00

  • Proteomic analysis of blood level of proteins before and after operation in patients with esophageal squamous cell carcinoma at high-incidence area in Henan Province.

    abstract:AIM:To characterize the protein files in blood from same patients with esophageal squamous cell carcinoma (ESCC) before and after operation at the high-incidence area for ESCC in Henan Province, China. METHODS:Two-dimensional electrophoresis, silver staining and ImageMaster 2-DE analysis software were applied to the d...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i22.3365

    authors: An JY,Fan ZM,Zhuang ZH,Qin YR,Gao SS,Li JL,Wang LD

    更新日期:2004-11-15 00:00:00

  • Sp1 contributes to overexpression of stanniocalcin 2 through regulation of promoter activity in colon adenocarcinoma.

    abstract:BACKGROUND:Aberrant expression of stanniocalcin 2 (STC2) is implicated in colon adenocarcinoma (COAD). A previous study identified that STC2 functions as a tumor promoter to drive development of some cancers, but the role of its overexpression in the development of COAD remains unclear. AIM:To evaluate the regulation ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i22.2776

    authors: Li JB,Liu ZX,Zhang R,Ma SP,Lin T,Li YX,Yang SH,Zhang WC,Wang YP

    更新日期:2019-06-14 00:00:00

  • Patient education improves adherence to peg-interferon and ribavirin in chronic genotype 2 or 3 hepatitis C virus infection: a prospective, real-life, observational study.

    abstract:AIM:To evaluate the impact of therapeutic education on adherence to antiviral treatment and sustained virological response (SVR) in a real-life setting in genotype 2/3 hepatitis C, as there are few adherence data in genotype 2/3 infection, even from randomized trials. METHODS:This prospective survey included genotype ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.14.6195

    authors: Cacoub P,Ouzan D,Melin P,Lang JP,Rotily M,Fontanges T,Varastet M,Chousterman M,Marcellin P

    更新日期:2008-10-28 00:00:00

  • An extremely rare case of pancreatic metastasis of esophageal squamous cell carcinoma.

    abstract::We report a rare case of a 68-year-old male with metachronous pancreatic metastasis that was resected 2 years after salvage esophagectomy for local recurrence of esophageal squamous cell carcinoma (ESCC). Two years and 8 mo ago, he had undergone definitive chemoradiotherapy for the lower thoracic ESCC and achieved a c...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i2.593

    authors: Okamoto H,Hara Y,Chin M,Hagiwara M,Onodera Y,Horii S,Shirahata Y,Kamei T,Hashizume E,Ohuchi N

    更新日期:2014-01-14 00:00:00

  • Frequency and prognostic role of mucosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy.

    abstract:AIM:To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatment after stopping the biologicals in patients with Crohn's disease (CD) and ulcerative colitis (UC). METHODS:The data from 41 patients with CD and 22 patients w...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v20.i11.2995

    authors: Farkas K,Lakatos PL,Szűcs M,Pallagi-Kunstár É,Bálint A,Nagy F,Szepes Z,Vass N,Kiss LS,Wittmann T,Molnár T

    更新日期:2014-03-21 00:00:00

  • Predictive factors associated with malignancy of intraductal papillary mucinous pancreatic neoplasms.

    abstract:AIM:To identify preoperative predictive factors associated with malignancy of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. METHODS:Between April 1995 and April 2010, 129 patients underwent surgical resection for IPMNs at our institute and had confirmed pathologic diagnoses. The medical records wer...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i42.5353

    authors: Lee JH,Lee KT,Park J,Bae SY,Lee KH,Lee JK,Jang KT,Heo JS,Choi SH,Choi DW,Rhee JC

    更新日期:2010-11-14 00:00:00

  • Transformation of hepatitis B serologic markers in babies born to hepatitis B surface antigen positive mothers.

    abstract:AIM:To better understand the clinical significance of hepatitis B serologic markers in babies born to hepatitis B surface antigen (HBsAg) positive mothers, the incidence of maternal serologic markers of hepatitis B via placenta and its transformation in these babies were investigated. METHODS:Mothers with positive HBs...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i23.3582

    authors: Wang JS,Chen H,Zhu QR

    更新日期:2005-06-21 00:00:00

  • Impact of small-for-size liver grafts on medium-term and long-term graft survival in living donor liver transplantation: A meta-analysis.

    abstract:BACKGROUND:Small-for-size grafts (SFSGs) in living donor liver transplantation (LDLT) could optimize donor postoperative outcomes and also expand the potential donor pool. Evidence on whether SFSGs would affect medium-term and long-term recipient graft survival is lacking. AIM:To evaluate the impact of small-for-size ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.3748/wjg.v25.i36.5559

    authors: Ma KW,Wong KHC,Chan ACY,Cheung TT,Dai WC,Fung JYY,She WH,Lo CM,Chok KSH

    更新日期:2019-09-28 00:00:00

  • Ulcerative colitis patients in clinical remission demonstrate correlations between fecal immunochemical test results, mucosal healing, and risk of relapse.

    abstract:AIM:To assess the risk of relapse in ulcerative colitis (UC) patients in clinical remission using mucosal status and fecal immunochemical test (FIT) results. METHODS:The clinical outcomes of 194 UC patients in clinical remission who underwent colonoscopy were based on evaluations of Mayo endoscopic subscores (MESs) an...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i21.5079

    authors: Nakarai A,Kato J,Hiraoka S,Takashima S,Takei D,Inokuchi T,Sugihara Y,Takahara M,Harada K,Okada H

    更新日期:2016-06-07 00:00:00

  • Profiling of differentially expressed genes in human gastric carcinoma by cDNA expression array.

    abstract:AIM:To investigate the expression of cancer related genes in gastric carcinoma (GC) through the use of Atlas Human Cancer Array membranes with 588 well-characterized human genes related to cancer and tumor biology. METHODS:Hybridization of cDNA blotting membrane was performed with (32)P-labeled cDNA probes synthesized...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i4.580

    authors: Liu LX,Liu ZH,Jiang HC,Qu X,Zhang WH,Wu LF,Zhu AL,Wang XQ,Wu M

    更新日期:2002-08-01 00:00:00

  • Gastro-duodenal disease in Africa: Literature review and clinical data from Accra, Ghana.

    abstract::Gastroduodenal disease (GDD) was initially thought to be uncommon in Africa. Amongst others, lack of access to optimal health infrastructure and suspicion of conventional medicine resulted in the reported prevalence of GDD being significantly lower than that in other areas of the world. Following the increasing availa...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i26.3344

    authors: Archampong TN,Asmah RH,Richards CJ,Martin VJ,Bayliss CD,Botão E,David L,Beleza S,Carrilho C

    更新日期:2019-07-14 00:00:00

  • Esophageal intramural pseudodiverticulosis of the residual esophagus after esophagectomy for esophageal cancer.

    abstract::A 91-year-old man was referred to our hospital with intermittent dysphagia. He had undergone esophagectomy for esophageal cancer (T3N2M0 Stage III) 11 years earlier. Endoscopic examination revealed an anastomotic stricture; signs of inflammation, including redness, erosion, edema, bleeding, friability, and exudate wit...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i30.9223

    authors: Takeshita N,Kanda N,Fukunaga T,Kimura M,Sugamoto Y,Tasaki K,Uesato M,Sazuka T,Maruyama T,Aida N,Tamachi T,Hosokawa T,Asai Y,Matsubara H

    更新日期:2015-08-14 00:00:00

  • Elastography-based screening for esophageal varices in patients with advanced chronic liver disease.

    abstract::Elastography-based liver stiffness measurement (LSM) is a non-invasive tool for estimating liver fibrosis but also provides an estimate for the severity of portal hypertension in patients with advanced chronic liver disease (ACLD). The presence of varices and especially of varices needing treatment (VNT) indicates dis...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v25.i3.308

    authors: Paternostro R,Reiberger T,Bucsics T

    更新日期:2019-01-21 00:00:00

  • Antifibrotic effects of green tea on in vitro and in vivo models of liver fibrosis.

    abstract:AIM:To examine the protective effect of green tea extract (GT) on hepatic fibrosis in vitro and in vivo in dimethylnitrosamine (DMN)-induced rats. METHODS:HSC-T6, a rat hepatic stellate cell line, was used as an in vitro assay system. Cell proliferation, collagen content, and type 1 collagen expression were examined i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.5200

    authors: Kim HK,Yang TH,Cho HY

    更新日期:2009-11-07 00:00:00

  • Antioxidative status of patients with alcoholic liver disease in southeastern Taiwan.

    abstract:AIM:To investigate the antioxidative status of patients with alcoholic liver disease (ALD) in southeastern Taiwan. METHODS:Our study comprised 27 patients with ALD recruited from Taitung Mackay Memorial Hospital, located in southeastern Taiwan. Patients with ALD included 12 non-aborigines (12 men) and 15 aborigines (1...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i8.1063

    authors: Chen YL,Chen LJ,Bair MJ,Yao ML,Peng HC,Yang SS,Yang SC

    更新日期:2011-02-28 00:00:00

  • Micronucleus analysis in patients with colorectal adenocarcinoma and colorectal polyps.

    abstract:AIM:To determine, by counting micronucleus (MN) frequencies, whether chromosomal or DNA damage have an effect on the pathogenesis of early colorectal adenocarcinoma (CRC). METHODS:We analyzed MN frequencies in 21 patients with CRC, 24 patients with colon polyps [10 neoplastic polyps (NP) and 14 non-neoplastic polyps (...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.6835

    authors: Karaman A,Binici DN,Kabalar ME,Calikuşu Z

    更新日期:2008-11-28 00:00:00

  • Analysis of the nitric oxide-cyclic guanosine monophosphate pathway in experimental liver cirrhosis suggests phosphodiesterase-5 as potential target to treat portal hypertension.

    abstract:AIM:To investigate the potential effect of inhibitors of phosphodiesterase-5 (PDE-5) for therapy of portal hypertension in liver cirrhosis. METHODS:In the rat model of thioacetamide-induced liver fibrosis/cirrhosis the nitric oxide-cyclic guanosine monophosphate (NO-cGMP) pathway was investigated. Expression and local...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i38.4356

    authors: Schaffner D,Lazaro A,Deibert P,Hasselblatt P,Stoll P,Fauth L,Baumstark MW,Merfort I,Schmitt-Graeff A,Kreisel W

    更新日期:2018-10-14 00:00:00

  • Rare case of pancreatic cancer with leptomeningeal carcinomatosis.

    abstract::Leptomeningeal carcinomatosis occurs very rarely in patients with pancreatic cancer. Leptomeningeal carcinomatosis is characterized by multifocal seeding of the leptomeninges by malignant cells that originate from a solid tumor. To the best of our knowledge, brain metastasis from pancreatic cancer is extremely rare. L...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i3.1020

    authors: Yoo IK,Lee HS,Kim CD,Chun HJ,Jeen YT,Keum B,Kim ES,Choi HS,Lee JM,Kim SH,Nam SJ,Hyun JJ

    更新日期:2015-01-21 00:00:00

  • Impact of comorbidities on the severity of chronic hepatitis B at presentation.

    abstract:AIM:To evaluate the clinical relevance of each cofactor on clinical presentation of chronic hepatitis B. METHODS:Out of 1366 hepatitis B surface antigen (HBsAg) positive subjects consecutively observed in 79 Italian hospitals, 53 (4.3%) showed as the only cofactor hepatitis D virus (HDV) infection [hepatitis B virus (...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v18.i14.1616

    authors: Sagnelli E,Stroffolini T,Mele A,Imparato M,Sagnelli C,Coppola N,Almasio PL

    更新日期:2012-04-14 00:00:00

  • Construction, expression and tumor targeting of a single-chain Fv against human colorectal carcinoma.

    abstract:AIM:A single-chain antibody fragment, ND-1scFv, against human colorectal carcinoma was constructed and expressed in E.coli, and its biodistribution and pharmacokinetic properties were studied in mice bearing tumor. METHODS:V(H) and V(L) genes were amplified from hybridoma cell IC-2, secreting monoclonal antibody ND-1,...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i4.726

    authors: Fang J,Jin HB,Song JD

    更新日期:2003-04-01 00:00:00

  • Angioedema associated with Crohn's disease: response to biologics.

    abstract::A 46-year-old female patient with terminal ileum Crohn's disease and ankylosing spondylitis presented with recurrent angioedema and urticaria. Investigations ruled out hereditary angioedema, and environmental or food allergen triggers. She was diagnosed with chronic idiopathic urticaria with angioedema, and was treate...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i34.4787

    authors: Habal F,Huang V

    更新日期:2012-09-14 00:00:00

  • Fiber-modified adenoviral vector expressing the tumor necrosis factor-related apoptosis-inducing ligand gene from the human telomerase reverse transcriptase promoter induces apoptosis in human hepatocellular carcinoma cells.

    abstract:AIM:Because of a major resistance to chemotherapy, prognosis of hepatocellular carcinoma (HCC) is still poor. New treatments are required and gene therapy may be an option. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in multiple malignant tumors, and using adenoviral vectors has sh...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i17.2552

    authors: Jacob D,Schumacher G,Bahra M,Davis J,Zhu HB,Zhang LD,Teraishi F,Neuhaus P,Fang BL

    更新日期:2005-05-07 00:00:00

  • Human papillomavirus does not have a causal role in colorectal carcinogenesis.

    abstract:AIM:To investigate the presence of human papillomavirus (HPV) DNA along with the integration, the quantification and the expression of the HPV16 in colorectal cancers. METHODS:A prospective series of colorectal tumors were genotyped for HPV DNA. The clinical and pathological variables of the HPV-positive tumors were c...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i1.342

    authors: Lorenzon L,Mazzetta F,Pilozzi E,Uggeri G,Torrisi MR,Ferri M,Ziparo V,French D

    更新日期:2015-01-07 00:00:00

  • Early steroid withdrawal after liver transplantation for hepatocellular carcinoma.

    abstract:AIM:To evaluate the impact of early steroid withdrawal on the incidence of rejection, tumor recurrence and complications after liver transplantation for advanced-stage hepatocellular carcinoma. METHODS:Fifty-four patients underwent liver transplantation for advanced-stage hepatocellular carcinoma from April 2003 to Ju...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i39.5273

    authors: Chen ZS,He F,Zeng FJ,Jiang JP,Du DF,Liu B

    更新日期:2007-10-21 00:00:00

  • Anti-proliferation effects of Twist gene silencing in gastric cancer SGC7901 cells.

    abstract:AIM:To study the role of Twist gene in gastric cancer by gene silencing, including the potential of induction of apoptosis, cell cycle arrest, and proliferation inhibition in human malignant gastric SGC7901 cells. METHODS:The expression level of Twist in gastric cancer samples was measured by immunohistochemistry. The...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i10.2926

    authors: Zhang H,Gong J,Kong D,Liu HY

    更新日期:2015-03-14 00:00:00

  • Apoptosis mechanisms of human gastric cancer cell line MKN-45 infected with human mutant p27.

    abstract:AIM:To explore the inducing effect of human mutant p27 gene on the apoptosis of the human gastric cancer cell line MKN-45 and its associated mechanisms. METHODS:The recombinant adenovirus Ad-p27mt was constructed to infect the human gastric cancer cell line MKN-45. Using flow cytometry, TUNEL assay and DNA fragment an...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i47.7536

    authors: Zhu JS,Wang L,Cheng GQ,Li Q,Zhu ZM,Zhu L

    更新日期:2005-12-21 00:00:00

  • Response evaluation of chemotherapy in metastatic colorectal cancer by contrast enhanced ultrasound.

    abstract:AIM:To evaluate whether contrast enhanced ultrasound (CEUS) might also be used for response prediction and early response evaluation in patients receiving bevacizumab based chemotherapy for metastasized colorectal cancer. METHODS:Thirty consecutive patients with non primary resectable liver metastases from colorectal ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i6.541

    authors: Schirin-Sokhan R,Winograd R,Roderburg C,Bubenzer J,do Ó NC,Guggenberger D,Hecker H,Trautwein C,Tischendorf JJ

    更新日期:2012-02-14 00:00:00