Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon.

abstract：AIM:The use of low-dose aspirin to prevent cardiovascular disease events is well established. However, the incidence and predictors of upper gastrointestinal bleeding (UGIB) with its use are unknown. We studied prospectively the incidence and outcome of peptic ulceration in low-dose aspirin users. METHODS:A total of 9...

journal_title：World journal of gastroenterology

authors： Ng W,Wong WM,Chen WH,Tse HF,Lee PY,Lai KC,Li SW,Ng M,Lam KF,Cheng X,Lau CP

更新日期：2006-05-14 00:00:00

abstract：AIM:To investigate the effects of Terminalia arjuna (T. arjuna) extract on human hepatoma cell line (HepG2) and its possible role in induction of apoptosis. METHODS:Human hepatoma cells were treated with different concentrations of ethanolic extract of T. arjuna and its cytotoxicity effect was measured by trypan blue ...

journal_title：World journal of gastroenterology

authors： Sivalokanathan S,Vijayababu MR,Balasubramanian MP

更新日期：2006-02-21 00:00:00

abstract：AIM:To assess the safety and efficacy of antioxidant therapy for patients with chronic hepatitis C virus (HCV) infection. METHODS:One hundred chronic HCV infection patients failed in interferon treatment were enrolled and randomly assigned to receive combined intravenous and oral antioxidants or placebo, or oral treat...

journal_title：World journal of gastroenterology

authors： Gabbay E,Zigmond E,Pappo O,Hemed N,Rowe M,Zabrecky G,Cohen R,Ilan Y

更新日期：2007-10-28 00:00:00

abstract：:The search for biomarkers that characterize specific aspects of inflammatory bowel disease (IBD), has received substantial interest in the past years and is moving forward rapidly with the help of modern technologies. Nevertheless, there is a direct demand to identify adequate biomarkers for predicting and evaluating ...

journal_title：World journal of gastroenterology

authors： Quetglas EG,Mujagic Z,Wigge S,Keszthelyi D,Wachten S,Masclee A,Reinisch W

更新日期：2015-11-28 00:00:00

abstract：AIM:To prepare the human hepatocellular carcinoma-(HCC)-targeted liposome microbubbles and to investigate their immunological properties. METHODS:Human hepatocarcinoma specific monoclonal antibody HAb18 was attached to the surface of home-made liposome microbubbles by static attraction to prepare the targeted liposome...

journal_title：World journal of gastroenterology

authors： Bian AN,Gao YH,Tan KB,Liu P,Zeng GJ,Zhang X,Liu Z

更新日期：2004-12-01 00:00:00

abstract：:The liver is the commonest site of distant metastasis of colorectal cancer and nearly half of the patients with colorectal cancer ultimately develop liver involved during the course of their diseases. Surgery is the only therapy that offers the possibility of cure for patients with hepatic metastatic diseases. Five-ye...

journal_title：World journal of gastroenterology

authors： Liu LX,Zhang WH,Jiang HC

更新日期：2003-02-01 00:00:00

abstract：AIM:To investigate the risk factors of colon cancer and rectal cancer. METHODS:A nested case-control study was conducted in a cohort of 64 693 subjects who participated in a colorectal cancer screening program from 1989 to 1998 in Jiashan county, Zhejiang, China. 196 cases of colorectal cancer were detected from 1990 ...

journal_title：World journal of gastroenterology

authors： Chen K,Cai J,Liu XY,Ma XY,Yao KY,Zheng S

更新日期：2003-01-01 00:00:00

abstract：:Colorectal cancer remains the third most common cancer in both women and men worldwide. Identifying modifiable dietary factors is crucial in developing primary prevention strategies. Vitamin B6 is involved in more than 100 coenzyme reactions, and may influence colorectal cancer risk in multiple ways including through ...

journal_title：World journal of gastroenterology

authors： Zhang XH,Ma J,Smith-Warner SA,Lee JE,Giovannucci E

更新日期：2013-02-21 00:00:00

abstract：AIM:To investigate the effects of exogenous melatonin on bacterial translocation and apoptosis in a rat ulcerative colitis model. METHODS:Rats were randomly assigned to three groups: group I: control, group II: experimental colitis, group III: colitis plus melatonin treatment. On d 11 after colitis, plasma tumor necro...

journal_title：World journal of gastroenterology

authors： Akcan A,Kucuk C,Sozuer E,Esel D,Akyildiz H,Akgun H,Muhtaroglu S,Aritas Y

更新日期：2008-02-14 00:00:00

abstract：AIM:Heat shock protein (HSP)70 is over-expressed in human gastric cancer and plays an important role in the progression of this cancer. We investigated the effects of antisense HSP70 oligomer on human gastric cancer cell line SGC-7901, and its potential role in gene therapy for this cancer. METHODS:Human gastric cance...

journal_title：World journal of gastroenterology

authors： Zhao ZG,Shen WL

更新日期：2005-01-07 00:00:00

abstract：AIM:To identify esophageal cancer related gene2 (ECRG2) associated proteins and their possible interactions with ECRG2 gene. METHODS:In the yeast forward two-hybrid system, ECRG2 was fused with the DNA-binding domain (DBD) of Gal4 and human fetal liver cDNA library was fused with the transcriptional activation domain ...

journal_title：World journal of gastroenterology

authors： Cui YP,Wang JB,Zhang XY,Bi MX,Guo LP,Lu SH

更新日期：2003-09-01 00:00:00

abstract：:Confocal laser endomicroscopy (CLE) is a newly introduced procedure that provide real-time, high-resolution imaging of the gastrointestinal mucosa during endoscopy, allowing the visualization of the pathology of the mucosal epithelium with its cellular and subcellular structures. Recently, the use of CLE was reported ...

journal_title：World journal of gastroenterology

authors： De Palma GD,Rispo A

更新日期：2013-09-14 00:00:00

abstract：:Heterotopic pancreatic tissue within the stomach is rare and dysplasia within heterotopic pancreatic tissue is very rare. We present the first report of a patient with concurrent occurrence of heterotopic pancreas in the stomach with a gastrointestinal stromal tumour. ...

journal_title：World journal of gastroenterology

authors： Kaufman A,Storey D,Lee CS,Murali R

更新日期：2007-11-21 00:00:00

abstract：:Cholelithiasis occurs infrequently in the paediatric age group. Hereditary spherocytosis, sickle cell anaemia and thalassemia are the haemolytic disorders most commonly associated with development of gall stones in paediatric age group. The question is whether an isolated episode of haemolysis can cause gallstones. ...

journal_title：World journal of gastroenterology

authors： Kejariwal D

更新日期：2006-04-14 00:00:00

abstract：AIM:To investigate the effect of Jianweiyuyang (JWYY) granule on gastric ulcer recurrence and its mechanism in the treatment of gastric ulcer in rats. METHODS:Gastric ulcer in rats was induced according to Okeba's method with minor modification and the recurrence model was induced by IL-1beta. The expression of vascul...

journal_title：World journal of gastroenterology

authors： Dai XP,Li JB,Liu ZQ,Ding X,Huang CH,Zhou B

更新日期：2005-09-21 00:00:00

abstract：:The incidence of Barrett's metaplasia (BM) as well as Barrett's adenocarcinoma (BA) has been increasing in western populations. The prognosis of BA is worse because individuals present at a late stage. Attempts have been made to intervene at early stage using surveillance programmes, although proof of efficacy of endo...

journal_title：World journal of gastroenterology

authors： Ishaq S,Jankowski JA

更新日期：2001-08-01 00:00:00

abstract：AIM:To examine the effect of hepatitis C virus (HCV) structural mimics of regulatory regions of the genome on HCV replication. METHODS:HCV RNA structural mimics were constructed and tested in a HCV genotype 1b aBB7 replicon, and a Japanese fulminant hepatitis-1 (JFH-1) HCV genotype 2a infection model. All sequences we...

journal_title：World journal of gastroenterology

authors： Smolic R,Smolic M,Andorfer JH,Wu CH,Smith RM,Wu GY

更新日期：2010-05-07 00:00:00

abstract：AIM:To establish the safety and efficacy of an indigenously developed r-hepatitis B vaccine using an accelerated schedule and to highlight the social awareness and commitment in preventing the spreading of hepatitis B virus infection. METHODS:The study was a multicentric, double blind, randomized (3:1) study using thr...

journal_title：World journal of gastroenterology

authors： Chowdhury A,Santra A,Habibullah CM,Khan AA,Karunakaramaiah J,Kishore TS,Raju AV,Lahiri S

更新日期：2005-02-21 00:00:00

abstract：:Hemolymphangioma is a malformation of both lymphatic vessels and blood vessels. Splenic hemolymphangioma is extremely rare. Herein, we present a case of 62-year-old woman with ambiguous upper quadrant abdominal pain for two months who was found to have an occupying lesion in the spleen on computed tomography. She was ...

journal_title：World journal of gastroenterology

authors： Mei Y,Peng CJ,Chen L,Li XX,Li WN,Shu DJ,Xie WT

更新日期：2015-05-07 00:00:00

abstract：AIM:To investigate the frequency and risk factors for acute pancreatitis after pancreatic guidewire placement (P-GW) in achieving cannulation of the bile duct during endoscopic retrograde cholangio-pancreatography (ERCP). METHODS:P-GW was performed in 113 patients in whom cannulation of the bile duct was difficult. Th...

journal_title：World journal of gastroenterology

authors： Ito K,Fujita N,Noda Y,Kobayashi G,Obana T,Horaguchi J,Takasawa O,Koshita S,Kanno Y

更新日期：2008-09-28 00:00:00

abstract：AIM:To determine the efficacy and safety benefits of performing intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC) to treat symptomatic cholelithiasis. METHODS:Patients admitted to the Minimally Invasive Surgery Center of Tianjin Nankai Hospital between January 2012 and January 2014 for mana...

journal_title：World journal of gastroenterology

authors： Ding GQ,Cai W,Qin MF

更新日期：2015-02-21 00:00:00

abstract：AIM:To detect the expression of DPC4 in malignant and non-malignant specimens of human pancreas, and observe the inhibition of retroviral pLXSN containing DPC4 on pancreatic carcinoma cells in vitro. METHODS:The expression of DPC4 was determined in 40 pancreatic adenocarcinoma and 36 non-malignant pancreatic specimens...

journal_title：World journal of gastroenterology

authors： Shen W,Tao GQ,Li DC,Zhu XG,Bai X,Cai B

更新日期：2008-10-28 00:00:00

abstract：AIM:To investigate the expression and clinical significance of B7 homolog 3 (B7-H3) and β-1,3-galactosyltransferase-4 (B3GALT4) in colorectal cancer (CRC) patients. METHODS:Using tissue microarray, we identified the expression of B7-H3 and B3GALT4 in 223 CRC patient samples by immunohistochemistry and evaluated the po...

journal_title：World journal of gastroenterology

authors： Zhang T,Wang F,Wu JY,Qiu ZC,Wang Y,Liu F,Ge XS,Qi XW,Mao Y,Hua D

更新日期：2018-08-21 00:00:00

abstract：AIM:To determine the evolution of transient elastography (TE) in patients with alcoholic liver disease according to alcohol cessation or continuation. METHODS:We retrospectively selected in our local database all patients who had two TE between June 2005 and November 2010 with chronic alcohol excessive consumption and...

journal_title：World journal of gastroenterology

authors： Bardou-Jacquet E,Legros L,Soro D,Latournerie M,Guillygomarc'h A,Le Lan C,Brissot P,Guyader D,Moirand R

更新日期：2013-01-28 00:00:00

abstract：AIM:To describe the learning curves of hand-assisted laparoscopic D2 radical gastrectomy (HALG) for the treatment of gastric cancer. METHODS:The HALG surgical procedure consists of three stages: surgery under direct vision via the port for hand assistance, hand-assisted laparoscopic surgery, and gastrointestinal tract...

journal_title：World journal of gastroenterology

authors： Gong JQ,Cao YK,Wang YH,Zhang GH,Wang PH,Luo GD

更新日期：2015-02-07 00:00:00

abstract：AIM:To investigate the effects of small interference RNA (siRNA) targeting of Cdx2 on human gastric cancer MGC-803 cells in vitro and in vivo. METHODS:The recombinant pSilencer 4.1-Cdx2 siRNA plasmids were constructed and transfected into gastric cancer MGC-803 cells in vitro. The stable transfectants were selected. T...

journal_title：World journal of gastroenterology

authors： Wang XT,Xie YB,Xiao Q

更新日期：2012-04-28 00:00:00

abstract：AIM:To investigate the role of MHC class II in the modulation of gastric epithelial cell apoptosis induced by H pylori infection. METHODS:After stimulating a human gastric epithelial cell line with bacteria or agonist antibodies specific for MHC class II and CD95, the quantitation of apoptotic and anti-apoptotic event...

journal_title：World journal of gastroenterology

authors： Bland DA,Suarez G,Beswick EJ,Sierra JC,Reyes VE

更新日期：2006-08-07 00:00:00

abstract：AIM:To investigate whether mesenchymal stem cells (MSCs) from adipose-derived stromal cells (ADSCs) and bone marrow stromal cells (BMSCs) have similar hepatic differentiation potential. METHODS:Mouse ADSCs and BMSCs were isolated and cultured. Their morphological and phenotypic characteristics, as well as their multip...

journal_title：World journal of gastroenterology

authors： Xu LJ,Wang SF,Wang DQ,Ma LJ,Chen Z,Chen QQ,Wang J,Yan L

更新日期：2017-10-14 00:00:00

abstract：AIM:To test the hypothesis that enhancement of the activity of heme oxygenase can interfere with processes of fibrogenesis associated with recurrent liver injury, we investigated the therapeutic potential of over-expression of heme oxygense-1 in a CCl(4)-induced micronodular cirrhosis model. METHODS:Recombinant adeno-...

journal_title：World journal of gastroenterology

authors： Tsui TY,Lau CK,Ma J,Glockzin G,Obed A,Schlitt HJ,Fan ST

更新日期：2006-04-07 00:00:00

abstract：AIM:To analyze the benefits and harms of pancreatic cancer screening in familial high-risk individuals (HRIs). METHODS:Studies were identified by searching PubMed, EBSCO, ClinicalTrials.gov and the Cochrane database from database inception to June 2014. We also obtained papers from the reference lists of pertinent stu...

journal_title：World journal of gastroenterology

authors： Lu C,Xu CF,Wan XY,Zhu HT,Yu CH,Li YM

更新日期：2015-07-28 00:00:00