Biological therapy for ulcerative colitis: an update.

abstract：:Despite advances in the treatment of gastric cancer, it remains the world's second highest cause of cancer death. As gastric cancer is often diagnosed at an advanced stage, systemic chemotherapy is the mainstay of treatment for these patients. However, no standard palliative chemotherapy regimen has been accepted for ...

journal_title：World journal of gastroenterology

authors： Bilici A

更新日期：2014-04-14 00:00:00

abstract：:Duodenal duplication cysts are benign rare congenital anomalies reported mainly in the pediatric population, but seldom in adults. Symptoms depend on the type and location and can present as abdominal pain, distension, dysphagia or dyspepsia. They have been reported to be responsible for duodenal obstruction, pancreat...

journal_title：World journal of gastroenterology

authors： Ko SY,Ko SH,Ha S,Kim MS,Shin HM,Baeg MK

更新日期：2013-10-14 00:00:00

abstract：AIM:To study the effect of selenium on peripheral blood mononuclear cell (PBMC) membrane fluidity and immune function in patients with chronic hepatitis. METHODS:PBMCs were pretreated with selenium (1.156x10(-7) mol/L) for 6 h in vitro or extracted directly from patients after administration of selenium-yeast continuo...

journal_title：World journal of gastroenterology

authors： He SX,Wu B,Chang XM,Li HX,Qiao W

更新日期：2004-12-01 00:00:00

abstract：AIM:To study the origin of calcium necessary for agonist-induced contraction of the distal colon in rats. METHODS:The change in intracellular calcium concentration ([Ca2+]i) evoked by elevating external Ca2+ was detected by fura 2/AM fluorescence. Contractile activity was measured with a force displacement transducer....

journal_title：World journal of gastroenterology

authors： Zhou H,Kong DH,Pan QW,Wang HH

更新日期：2008-02-21 00:00:00

abstract：AIM:To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS:Production of recombinant sH2a and development of a monoclonal antibody and an enzyme-linked immunosorbent assay (ELISA). This assay was used to determine the presence and concentrati...

journal_title：World journal of gastroenterology

authors： Benyair R,Kondratyev M,Veselkin E,Tolchinsky S,Shenkman M,Lurie Y,Lederkremer GZ

更新日期：2011-12-28 00:00:00

abstract：:The progressive loss of efficacy of standard eradication therapies has made the treatment of Helicobacter pylori (H. pylori) more challenging than ever. Endoscopic-guided antibiotic susceptibility testing had previously been suggested to guide treatment after failure of second-line therapies. However, its role has exp...

journal_title：World journal of gastroenterology

authors： Cammarota G,Ianiro G,Bibbò S,Di Rienzo TA,Masucci L,Sanguinetti M,Gasbarrini A

更新日期：2014-05-14 00:00:00

abstract：:Studies on rodents and humans demonstrate an inherited predisposition to hepatocellular carcinoma (HCC). Analysis of the molecular alterations involved in the acquisition of a phenotype resistant or susceptible to hepatocarcinogenesis showed a deregulation of G1 and S phases in HCC of genetically susceptible F344 rats...

journal_title：World journal of gastroenterology

authors： Feo F,Frau M,Pascale RM

更新日期：2008-11-21 00:00:00

abstract：AIM:To evaluate the impact of early steroid withdrawal on the incidence of rejection, tumor recurrence and complications after liver transplantation for advanced-stage hepatocellular carcinoma. METHODS:Fifty-four patients underwent liver transplantation for advanced-stage hepatocellular carcinoma from April 2003 to Ju...

journal_title：World journal of gastroenterology

authors： Chen ZS,He F,Zeng FJ,Jiang JP,Du DF,Liu B

更新日期：2007-10-21 00:00:00

abstract：AIM:To investigate the role of heme oxygenase-1 (HO-1) in pathogenesis of experimental hepatorenal syndrome (HRS). METHODS:Rats were divided into liver cirrhotic group, zinc protoporphyrin IX (ZnPP) treatment group, cobalt protoporphyrin (CoPP) treatment group and sham group. Biliary cirrhosis was established by bile ...

journal_title：World journal of gastroenterology

authors： Guo SB,Duan ZJ,Li Q,Sun XY

更新日期：2011-01-21 00:00:00

abstract：AIM:To establish the therapeutic potential of proteasome inhibition, we examined the therapeutic effects of MG132 (Z-Leu-Leu-Leu-aldehyde) in an experimental model of acute pancreatitis. METHODS:Pancreatitis was induced in rats by two hourly intraperitoneal (ip) injections of cholecystokinin octapeptide (CCK; 2 x 100 ...

journal_title：World journal of gastroenterology

authors： Letoha T,Fehér LZ,Pecze L,Somlai C,Varga I,Kaszaki J,Tóth G,Vizler C,Tiszlavicz L,Takács T

更新日期：2007-09-07 00:00:00

abstract：AIM:To determine the association of human antigen R (HuR) and inhibitors of apoptosis proteins (IAP1, IAP2) and prognosis in pancreatic cancer. METHODS:Protein and mRNA expression levels of IAP1, IAP2 and HuR in pancreatic ductal adenocarcinoma (PDAC) were compared with normal pancreatic tissue. The correlations among...

journal_title：World journal of gastroenterology

authors： Lukosiute-Urboniene A,Jasukaitiene A,Silkuniene G,Barauskas V,Gulbinas A,Dambrauskas Z

更新日期：2019-01-14 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that might affect up to one-third of the adult population in industrialised countries. NAFLD incorporates histologically and clinically different non-alcoholic entities; fatty liver (NAFL, steatosis hepatis) and steatohepatitis (NASH-characterised by...

journal_title：World journal of gastroenterology

authors： Firneisz G

更新日期：2014-07-21 00:00:00

abstract：:AIM:To explore the risk factors of gallbladder stone recurrence.METHODS:A multifactorial analysis was made for 1058 patients in Shanghai area whose gallbladder stones disappeared after different kinds of nonsurgical therapy,including oral litholytic therapy, extracorporeal shock wave lithotripsy and percutaneous chole...

journal_title：World journal of gastroenterology

authors： Chen P,Wang BS,He LQ

更新日期：1999-02-01 00:00:00

abstract：:Biodegradable stents (BDSs) are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines. The experience with the currently the only BDS for endoscopic placement, made of Poly-dioxanone, have shown promising results. However some aspects should be imp...

journal_title：World journal of gastroenterology

authors： Lorenzo-Zúñiga V,Moreno-de-Vega V,Marín I,Boix J

更新日期：2014-03-07 00:00:00

abstract：:The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), may be complicated by colorectal cancer (CRC). In a recent population-based cohort study of 47 347 Danish patients with IBD by Tine Jess and colleagues 268 patients with UC and 70 patients with CD developed CRC during 30 years of ...

journal_title：World journal of gastroenterology

authors： Andersen V,Halfvarson J,Vogel U

更新日期：2012-08-21 00:00:00

abstract：:Irritable bowel syndrome (IBS) is an extremely prevalent but poorly understood gastrointestinal disorder. Consequently, there are no clear diagnostic markers to help diagnose the disorder and treatment options are limited to management of the symptoms. The concept of a dysregulated gut-brain axis has been adopted as a...

journal_title：World journal of gastroenterology

authors： Kennedy PJ,Cryan JF,Dinan TG,Clarke G

更新日期：2014-10-21 00:00:00

abstract：:The pancreatic manifestations seen in patients with von Hippel-Lindau (VHL) disease are subdivided into 2 categories: pancreatic neuroendocrine tumors (NET), and cystic lesions, including simple cyst and serous cystadenoma. The VHL-associated cystic lesions are generally asymptomatic and do not require any treatment, ...

journal_title：World journal of gastroenterology

authors： Tamura K,Nishimori I,Ito T,Yamasaki I,Igarashi H,Shuin T

更新日期：2010-09-28 00:00:00

abstract：:Previously, we reported the efficacy of a newly developed inverted overtube in shortening the hemostatic time and obtaining a clear endoscopic view in emergency endoscopic hemostasis. This device also helped us to perform gastric endoscopic submucosal dissection (ESD) more safely by changing the direction of gravity i...

journal_title：World journal of gastroenterology

authors： Mori H,Rafiq K,Kobara H,Nishiyama N,Fujihara S,Yachida T,Ayagi M,Tani J,Miyoshi H,Masaki T

更新日期：2014-02-14 00:00:00

abstract：AIM:To determine whether aspirin or non-aspirin non-steroidal anti-inflammatory drugs (NA-NSAIDs) prevent colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD). METHODS:We performed a systematic review and meta-analysis. We searched for articles reporting the risk of CRC in patients with IBD relate...

journal_title：World journal of gastroenterology

authors： Burr NE,Hull MA,Subramanian V

更新日期：2016-04-07 00:00:00

abstract：:The severity of fecal incontinence widely varies and can have dramatic devastating impacts on a person's life. Fecal incontinence is common, though it is often under-reported by patients. In addition to standard treatment options, new treatments have been developed during the past decade to attempt to effectively trea...

journal_title：World journal of gastroenterology

authors： Van Koughnett JA,Wexner SD

更新日期：2013-12-28 00:00:00

abstract：AIM:To investigate the individual and combined effects of allopurinol and hyperbaric oxygen (HBO) therapy on biochemical and histopathological changes, oxidative stress, and bacterial translocation (BT) in the experimental rat acute pancreatitis (AP). METHODS:Eighty-five Sprague-Dawley rats were included in the study....

journal_title：World journal of gastroenterology

authors： Comert B,Isik AT,Aydin S,Bozoglu E,Unal B,Deveci S,Mas N,Cinar E,Mas MR

更新日期：2007-12-14 00:00:00

abstract：:As the incidence of acute pancreatitis continues to rise, establishing the etiology in order to prevent recurrence is important. Although the etiology of acute pancreatitis is not difficult in the majority of patients, almost a quarter of patients are initially labeled as having idiopathic acute pancreatitis. When con...

journal_title：World journal of gastroenterology

authors： Tenner S

更新日期：2014-11-28 00:00:00

abstract：AIM:To elucidate high mobility group-box 3 (HMGB3) protein expression in gastric adenocarcinoma, its potential prognostic relevance, and possible mechanism of action. METHODS:Ninety-two patients with gastric adenocarcinomas surgically removed entered the study. HMGB3 expression was determined by immunohistochemistry t...

journal_title：World journal of gastroenterology

authors： Tang HR,Luo XQ,Xu G,Wang Y,Feng ZJ,Xu H,Shi YW,Zhang Q,Wu LG,Xue CQ,Wang CW,Wu CY

更新日期：2012-12-28 00:00:00

abstract：AIM:To investigate the presence or absence of high amplitude propagating contractions (HAPC), as well as the other measures of colonic motility, in persons with spinal cord injury (SCI). METHODS:Prolonged colonic ambulatory manometric studies were performed on 14 male volunteers: 8 with SCI (mean age, 59 ± 13 years; m...

journal_title：World journal of gastroenterology

authors： Ancha HR,Fajardo NR,Bauman WA,Rosman AS,Galea M,Creasey G,Korsten MA

更新日期：2010-11-21 00:00:00

abstract：AIM:To assess the importance of preoperative diagnosis and presentation of left-sided gallbladder using ultrasound (US), CT and angiography. METHODS:Retrospective review of 1482 patients who underwent enhanced CT scanning was performed. Left-sided gallbladder was diagnosed if a right-sided ligamentum teres was present...

journal_title：World journal of gastroenterology

authors： Hsu SL,Chen TY,Huang TL,Sun CK,Concejero AM,Tsang LL,Cheng YF

更新日期：2007-12-21 00:00:00

abstract：AIM:To assess the association between smoking and alcohol consumption and extrahepatic cholangiocarcinoma (ECC) through a meta-analysis of clinical observational studies. METHODS:A literature search was conducted using Embase and MEDLINE databases from inception to 31 May 2013 without language limitations, and by manu...

journal_title：World journal of gastroenterology

authors： Ye XH,Huai JP,Ding J,Chen YP,Sun XC

更新日期：2013-12-14 00:00:00

abstract：BACKGROUND:The role of the Notch pathway in carcinogenesis and tumor progression has been demonstrated in many organs, including the colon. Accordingly, studies aimed at developing therapies targeting this pathway in various cancers require the identification of several factors that may play a role in regulating Notch-...

journal_title：World journal of gastroenterology

authors： Gonulcu SC,Unal B,Bassorgun IC,Ozcan M,Coskun HS,Elpek GO

更新日期：2020-07-14 00:00:00

abstract：AIM:To evaluate the influence of multiple samplings during esophagogastroduodenoscopy (EGD) on the accuracy of the rapid urease test, and the validity of newly developed rapid urease tests, HelicotecUT plus test and HelicotecUT test, CLO test and ProntoDry test. METHODS:A total of 355 patients undergoing EGD for dyspe...

journal_title：World journal of gastroenterology

authors： Hsu WH,Wang SS,Kuo CH,Chen CY,Chang CW,Hu HM,Wang JY,Yang YC,Lin YC,Wang WM,Wu DC,Wu MT,Kuo FC

更新日期：2010-06-21 00:00:00

abstract：AIM:To assess the efficiency of endoscopic trans-esophageal submucosal tunneling surgery (EESTS) technique for diseases located around the aorta ventralis. METHODS:Nine pigs were assigned to EESTs. The procedures were as follows: First, a long esophageal submucosal tunnel was established. Second, full-thickness myotom...

journal_title：World journal of gastroenterology

authors： Xiong Y,Chen QQ,Chai NL,Jiao SC,Ling Hu EQ

更新日期：2019-01-07 00:00:00

abstract：AIM:To evaluate the effectiveness and safety of different portal vein branch embolization agents in inducing compensatory hypertrophy of the remnant liver and to offer a theoretic basis for clinical portal vein branch embolization. METHODS:Forty-one adult dogs were included in the experiment and divided into four grou...

journal_title：World journal of gastroenterology

authors： Huang JY,Yang WZ,Li JJ,Jiang N,Zheng QB

更新日期：2006-01-21 00:00:00