Interaction of major genes predisposing to hepatocellular carcinoma with genes encoding signal transduction pathways influences tumor phenotype and prognosis.

abstract：AIM:To investigate the effects of extended lymphadenectomy and postoperative chemotherapy on gastric cancer without lymph node metastasis. METHODS:Clinical data of 311 node-negative gastric cancer patients who underwent potentially curative gastrectomy with more than 15 lymph nodes resected, from January 2002 to Decem...

journal_title：World journal of gastroenterology

authors： Xue Q,Wang XN,Deng JY,Zhang RP,Liang H

更新日期：2013-09-07 00:00:00

abstract：AIM:To evaluate the association of glutathione S-transferase mu (GSTM1) and glutathione S-transferase theta (GSTT1) null genotypes with the risk of gastric cancer (GC) and colorectal cancer (CRC) in a South Korean population. METHODS:We conducted a population-based, large-scale case-control study including 2213 GCs, 1...

journal_title：World journal of gastroenterology

authors： Piao JM,Shin MH,Kweon SS,Kim HN,Choi JS,Bae WK,Shim HJ,Kim HR,Park YK,Choi YD,Kim SH

更新日期：2009-12-07 00:00:00

abstract：:Gastric cancer (GC) is one of the leading causes of cancer death in the world. Numerous efforts are being made to find chemoprotective agents able to reduce its risk. Amongst these, green tea has been reported to have a protective effect against stomach cancer. This article aims to critically evaluate all epidemiologi...

journal_title：World journal of gastroenterology

authors： Hou IC,Amarnani S,Chong MT,Bishayee A

更新日期：2013-06-28 00:00:00

abstract：AIM:To evaluate the effects of extrahepatic collaterals to the liver on liver damage and patient outcome after embolotherapy for the ruptured hepatic artery pseudoaneurysm following hepatobiliary pancreatic surgery. METHODS:We reviewed 9 patients who underwent transcatheter arterial embolization (TAE) for the ruptured...

journal_title：World journal of gastroenterology

authors： Tajima Y,Kuroki T,Tsutsumi R,Sakamoto I,Uetani M,Kanematsu T

更新日期：2007-01-21 00:00:00

abstract：AIM:To test the hypothesis that enhancement of the activity of heme oxygenase can interfere with processes of fibrogenesis associated with recurrent liver injury, we investigated the therapeutic potential of over-expression of heme oxygense-1 in a CCl(4)-induced micronodular cirrhosis model. METHODS:Recombinant adeno-...

journal_title：World journal of gastroenterology

authors： Tsui TY,Lau CK,Ma J,Glockzin G,Obed A,Schlitt HJ,Fan ST

更新日期：2006-04-07 00:00:00

abstract：:Single-incision laparoscopic surgery (SILS) and natural orifice transluminal endoscopic surgery (NOTES) have rapidly gained pace worldwide, potentially replacing conventional laparoscopic surgery (CLS) as the preferred colorectal surgery technique. Currently available data mainly consist of retrospective series analyz...

journal_title：World journal of gastroenterology

authors： Daher R,Chouillard E,Panis Y

更新日期：2014-12-28 00:00:00

abstract：:Autoimmune hepatitis (AIH) is an unresolving progressive liver disease of unknown etiology characterized by hypergammaglobulinemia, autoantibodies detection and interface hepatitis. Due to the absence of specific diagnostic markers and the large heterogeneity of its clinical, laboratory and histological features, AIH ...

journal_title：World journal of gastroenterology

authors： Gatselis NK,Zachou K,Koukoulis GK,Dalekos GN

更新日期：2015-01-07 00:00:00

abstract：:The evasion from controlled cell death induction has been considered as one of the hallmarks of cancer cells. Defects in cell death signaling are a fundamental phenomenon in colorectal cancer. Nearly any non-invasive cancer treatment finally aims to induce cell death. However, apoptosis resistance is the major cause f...

journal_title：World journal of gastroenterology

authors： Koehler BC,Jäger D,Schulze-Bergkamen H

更新日期：2014-02-28 00:00:00

abstract：AIM:To objectively evaluate the effect of TJ-68 on colonic spasms during colonoscopy. METHODS:One hundred and one patients subjected to screening colonoscopy were randomly assigned to two groups: TJ-68 in 51 subjects and saline as the control in 50. The endoscope was inserted into the sigmoid colon, then a spastic reg...

journal_title：World journal of gastroenterology

authors： Ai M,Yamaguchi T,Odaka T,Mitsuhashi K,Shishido T,Yan J,Seza A,Saisho H

更新日期：2006-02-07 00:00:00

abstract：:AIM:To investigate the incidence and management of nutritional deficiencies following a gastrectomy.METHODS:A gastrectomy population of 227 patients in London was followed up for 30 years after operation to detect and treat nutritional deficiencies.RESULTS:By the end of the first decade iron deficiency was the commone...

journal_title：World journal of gastroenterology

authors： Tovey FI,Hobsley M

更新日期：2000-02-01 00:00:00

abstract：AIM:To assess the efficacy and safety of fourth-generation quinolones for Helicobacter pylori (H. pylori) eradication, we conducted this systematic review and meta-analysis of randomized clinical trials. METHODS:Major literature databases (PubMed, EMBASE and the Cochrane Central Register of Controlled Trials) were sea...

journal_title：World journal of gastroenterology

authors： An Y,Wang Y,Wu S,Wang YH,Qian X,Li Z,Fu YJ,Xie Y

更新日期：2018-08-07 00:00:00

abstract：:The main treatment of patients with non-alcoholic fatty liver disease (NAFLD) is life style modification including weight reduction and dietary regimen. Majority of patients are safely treated with this management and pharmacologic interventions are not recommended. However, a subgroup of NAFLD patients with non-alcoh...

journal_title：World journal of gastroenterology

authors： Eshraghian A

更新日期：2017-11-14 00:00:00

abstract：AIM:To investigate the inhibitory effect of in vivo expression of expressing plasmid pCH510 of recombinant fibronectin polypeptide (CH50) on hepatocellular carcinoma and the improved therapeutic effect of pCH510 in combination with chemotherapeutic agents and Hsp70-H22 hepatocarcinoma antigen peptide on tumor. METHODS...

journal_title：World journal of gastroenterology

authors： Zhang GM,Yang Y,Huang B,Xiao H,Li D,Feng ZH

更新日期：2003-09-01 00:00:00

abstract：:AIM:To determine whether recombinant human epidermal growth factor (rhEGF) can protect gastric mucosa against ethanol induced injury in rats.METHOD: Fifty-four SD rats weighing 200g-500g each were divided into six groups after fasting for 24 hours.Three groups received different doses of oral rhEGF (30, 60 and 120&mgr...

journal_title：World journal of gastroenterology

authors： Xu CD,Gan RB,Chen SN,Jiang SH,Xu JY

更新日期：1998-10-01 00:00:00

abstract：AIM:CMU-1 is a new preservation solution with a low potassium concentration as well as low viscosity that is highly effective in reducing preservation injury. The purpose of this experiment is to compare the protective effect of CMU-1 solution with that of UW during cold preservation and normothermic reperfusion. METH...

journal_title：World journal of gastroenterology

authors： Cheng Y,Liu YF,Cheng DH,Li BF,Zhao N

更新日期：2005-04-28 00:00:00

abstract：:Multiple robotic flexible endoscope platforms have been developed based on cross specialty collaboration between engineers and medical doctors. However, significant number of these platforms have been developed for the natural orifice transluminal endoscopic surgery paradigm. Increasing amount of evidence suggest the ...

journal_title：World journal of gastroenterology

authors： Yeung BP,Chiu PW

更新日期：2016-02-07 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease that might affect up to one-third of the adult population in industrialised countries. NAFLD incorporates histologically and clinically different non-alcoholic entities; fatty liver (NAFL, steatosis hepatis) and steatohepatitis (NASH-characterised by...

journal_title：World journal of gastroenterology

authors： Firneisz G

更新日期：2014-07-21 00:00:00

abstract：AIM:To evaluate the efficacy and safety of capsule oxymatrine in the treatment of chronic hepatitis B. METHODS:A randomised double-blind and placebo-controlled multicenter trial was conducted. Injection of oxymatrine was used as positive-control drug. A total of 216 patients with chronic hepatitis B entered the study ...

journal_title：World journal of gastroenterology

authors： Lu LG,Zeng MD,Mao YM,Li JQ,Wan MB,Li CZ,Chen CW,Fu QC,Wang JY,She WM,Cai X,Ye J,Zhou XQ,Wang H,Wu SM,Tang MF,Zhu JS,Chen WX,Zhang HQ

更新日期：2003-11-01 00:00:00

abstract：:Crohn's disease (CD) is a chronic inflammatory condition that plagues millions all over the world. This debilitating bowel disease can start in early childhood and continue into late adulthood. Signs and symptoms are usually many and multiple tests are often required for the diagnosis and confirmation of this disease....

journal_title：World journal of gastroenterology

authors： Naser SA,Sagramsingh SR,Naser AS,Thanigachalam S

更新日期：2014-06-21 00:00:00

abstract：BACKGROUND:To date, the histopathological parameters predicting the risk of lymph node (LN) metastases and local recurrence, associated mortality and appropriateness of endoscopic or surgical resection in patients with gastric neuroendocrine neoplasms type 1 (GNENs1) have not been fully elucidated. AIM:To determine th...

journal_title：World journal of gastroenterology

authors： Tsolakis AV,Ragkousi A,Vujasinovic M,Kaltsas G,Daskalakis K

更新日期：2019-09-21 00:00:00

abstract：AIM:To compare the differences in the endoscopic classification of early colorectal carcinoma (CRC) between Japan and China. METHODS:Ten cases of early CRC were included in the study. After reviewing the color pictures of these cases, 5 Japanese endoscopists and 5 Chinese endoscopists made their classificatory diagnos...

journal_title：World journal of gastroenterology

authors： Zhu RM,Wang FY,Hirata I,Katsu K,Xiao SD,Yu ZL,Zhang ZH,Xu ZM

更新日期：2003-09-01 00:00:00

abstract：AIM:To evaluate the detection and differentiation ability of contrast-enhanced intraoperative ultrasonography (CE-IOUS) in hepatocellular carcinoma (HCC) operations. METHODS:Clinical data of 50 HCC patients were retrospective analyzed. The sensitivity, specificity, false negative and false positive rates of contrast e...

journal_title：World journal of gastroenterology

authors： Wu H,Lu Q,Luo Y,He XL,Zeng Y

更新日期：2010-01-28 00:00:00

abstract：AIM:To describe cases of gut perforation after orthotopic liver transplantation. METHODS:Data were collected from our center database and medical records. Six of 187 patients (3.2%) who underwent orthotopic liver transplantation from January to December 2005 developed gut perforation. All patients were male with an av...

journal_title：World journal of gastroenterology

authors： Xiong J,You S,He XS

更新日期：2007-04-14 00:00:00

abstract：AIM:To investigate the relationship between the expression of p16 gene and the gastric carcinogenesis, depth of invasion and lymph node metastases, and to evaluate the deletion and mutation of exon 2 in p16 gene in gastric carcinoma. METHODS:The expression of p16 protein was examined by streptavidin-peroxidase conjuga...

journal_title：World journal of gastroenterology

authors： He XS,Su Q,Chen ZC,He XT,Long ZF,Ling H,Zhang LR

更新日期：2001-08-01 00:00:00

abstract：AIM:To analyze the literature on the use of Chinese herbal medicines for the treatment of cholecystitis. METHODS:The literature on treatment of cholecystitis with traditional Chinese medicines (TCM) was analyzed based on the principles and methods described by evidence-based medicine (EBM). Eight databases including M...

journal_title：World journal of gastroenterology

authors： Dong ZY,Wang GL,Liu X,Liu J,Zhu DZ,Ling CQ

更新日期：2012-04-14 00:00:00

abstract：AIM:To perform a meta-analysis of observational studies to further elucidate the relationship between oral bisphosphonate use and gastrointestinal cancer risk. METHODS:Systematic literature search was conducted in MEDLINE, EMBASE, and the Cochrane Library to identify studies through January 2011. Search terms were "bi...

journal_title：World journal of gastroenterology

authors： Oh YH,Yoon C,Park SM

更新日期：2012-10-28 00:00:00

abstract：:A 67-year-old male underwent endoscopic submucosal dissection (ESD) to treat early gastric cancer (EGC) in 2001. The lesion (50 mm × 25 mm diameter) was histologically diagnosed as poorly differentiated adenocarcinoma, with an ulcer finding. Although the tumor was confined to the mucosa with no evidence of lymphovascu...

journal_title：World journal of gastroenterology

authors： Kawabata H,Oda I,Suzuki H,Nonaka S,Yoshinaga S,Katai H,Taniguchi H,Kushima R,Saito Y

更新日期：2013-08-14 00:00:00

abstract：AIM:Passive immunotherapy using antibody against hepatitis B surface antigen (HBsAg) has been advocated in certain cases of Hepatitis B infection. We had earlier reported on the cloning and expression of a high affinity scFv derived from a mouse monoclonal (5S) against HBsAg. However this mouse antibody cannot be used ...

journal_title：World journal of gastroenterology

authors： Bose B,Khanna N,Acharya SK,Sinha S

更新日期：2005-12-28 00:00:00

abstract：:Over the past decade, research has shown that aberrant expression of microRNA (miRNA) is involved in colorectal cancer development and progression. MicroRNAs are small sequences of non-coding RNA that regulate expression of genes involved in important cellular functions, such as cell differentiation, multiplication, a...

journal_title：World journal of gastroenterology

authors： Hollis M,Nair K,Vyas A,Chaturvedi LS,Gambhir S,Vyas D

更新日期：2015-07-21 00:00:00

abstract：BACKGROUND:Given the shortage of suitable liver grafts for liver transplantation, proper use of hepatitis B core antibody-positive livers might be a possible way to enlarge the donor pool and to save patients with end-stage liver diseases. However, the safety of hepatitis B virus core antibody positive (HBcAb+) donors ...

journal_title：World journal of gastroenterology

authors： Lei M,Yan LN,Yang JY,Wen TF,Li B,Wang WT,Wu H,Xu MQ,Chen ZY,Wei YG

更新日期：2018-12-28 00:00:00