Pancreatic biomarkers: could they be the answer?

abstract：:A 66-year-old woman underwent partial splenic embolization (PSE) for hypersplenism with idiopathic portal hypertension (IPH). One week later, contrast-enhanced CT revealed extensive portal vein thrombosis (PVT) and dilated portosystemic shunts. The PVT was not dissolved by the intravenous administration of urokinase. ...

journal_title：World journal of gastroenterology

authors： Nakai M,Sato M,Sahara S,Kawai N,Kimura M,Maeda Y,Ibata Y,Higashi K

更新日期：2006-08-21 00:00:00

abstract：AIM:To assess potential contributions of biliary IgA for crystal agglomeration into gallstones, we visualized cholesterol crystal binding of biliary IgA. METHODS:Crystal binding biliary proteins were extracted from human gallbladder bile using lectin affinity chromatography.Biliary IgA was isolated from the bound prot...

journal_title：World journal of gastroenterology

authors： Lammert F,Südfeld S,Busch N,Matern S

更新日期：2001-04-01 00:00:00

abstract：AIM:To assess the usefulness of contrast-enhanced harmonic endoscopic ultrasonography (CH-EUS) for lymph node metastasis in pancreatobiliary carcinoma. METHODS:All patients suspected of pancreatobiliary carcinoma with visible lymph nodes after standard EUS between June, 2009 and January, 2012 were enrolled. In the pri...

journal_title：World journal of gastroenterology

authors： Miyata T,Kitano M,Omoto S,Kadosaka K,Kamata K,Imai H,Sakamoto H,Nisida N,Harwani Y,Murakami T,Takeyama Y,Chiba Y,Kudo M

更新日期：2016-03-28 00:00:00

abstract：AIM:To investigate serum mean platelet volume (MPV) levels in acute pancreatitis (AP) patients and assess whether MPV effectively predicts the disease severity of AP. METHODS:We included 117 consecutive patients with AP as the AP group and 34 consecutive patients with colorectal polyps (before endoscopic treatment) as...

journal_title：World journal of gastroenterology

authors： Lei JJ,Zhou L,Liu Q,Xiong C,Xu CF

更新日期：2017-04-07 00:00:00

abstract：:Hepatoid adenocarcinoma of the stomach (HAS) is a rare form of gastric cancer that has unique clinicopathological features and an extremely poor prognosis. Here, we report on three patients with suspected gastric cancer who were referred to our hospital. Gastrointestinal fiberscopy on the three patients revealed two l...

journal_title：World journal of gastroenterology

authors： Ye MF,Tao F,Liu F,Sun AJ

更新日期：2013-07-21 00:00:00

abstract：:An estimated 300 million people worldwide suffer from chronic hepatitis C with a prevalence of 0.8%-1.0% of the general population in Canada. An increasing pool of evidence exists supporting the use of pegylated- interferon (pegIFN) and ribavirin combination therapy for hepatitis C. We report a 49-year old male of Nor...

journal_title：World journal of gastroenterology

authors： Zandieh I,Adenwalla M,Cheong-Lee C,Ma PE,Yoshida EM

更新日期：2006-08-14 00:00:00

abstract：AIM:To accurately and realistically elucidate human stem cell behaviors in vivo and the fundamental mechanisms controlling human stem cell fates in vivo, which is urgently required in regenerative medicine and treatments for some human diseases, a surrogate human-rat chimera model was developed. METHODS:Human-rat chim...

journal_title：World journal of gastroenterology

authors： Sun Y,Xiao D,Pan XH,Zhang RS,Cui GH,Chen XG

更新日期：2007-05-21 00:00:00

abstract：AIM:To investigate serum insulin-like growth factor-binding protein 5 (IGFBP-5) levels and intestinal IGFBP-5 expression in patients with Crohn's disease (CD). METHODS:We analyzed the serum concentrations and intestinal expression of IGFBP-5 in 42 patients with CD, of whom 26 had endoscopically or radiologically prove...

journal_title：World journal of gastroenterology

authors： Adali G,Yorulmaz E,Ozkanli S,Ulasoglu C,Bayraktar B,Orhun A,Colak Y,Tuncer I

更新日期：2013-12-21 00:00:00

abstract：AIM:To induce the tolerance of rat liver allograft by dendritic cells (DCs) modified with NF-kappaB decoy oligodeoxynucleotides (ODNs). METHODS:Bone marrow (BM)-derived DCs from SD rats were propagated in the presence of GM-CSF or GM-CSF+IL-4 to obtain immature DCs or mature DCs. GM-CSF+IL-4-propagated DCs were treate...

journal_title：World journal of gastroenterology

authors： Xu MQ,Suo YP,Gong JP,Zhang MM,Yan LN

更新日期：2004-08-15 00:00:00

abstract：:The aetiology of primary sclerosing cholangitis (PSC) is not known and controversy exists as to whether PSC should be denominated an autoimmune disease. A large number of autoantibodies have been detected in PSC patients, but the specificity of these antibodies is generally low, and the frequencies vary largely betwee...

journal_title：World journal of gastroenterology

authors： Hov JR,Boberg KM,Karlsen TH

更新日期：2008-06-28 00:00:00

abstract：AIM:To examine whether vitamin D improved viral response and predicted treatment outcome in patients with hepatitis C virus (HCV) genotype 2-3. METHODS:Fifty patients with chronic HCV genotype 2-3 were randomized consecutively into two groups: Treatment group [20 subjects, age 48 ± 14 years, body mass index (BMI) 30 ±...

journal_title：World journal of gastroenterology

authors： Nimer A,Mouch A

更新日期：2012-02-28 00:00:00

abstract：AIM:To investigate the safety and efficacy of adding bevacizumab to first-line chemotherapy in metastatic colorectal cancer patients with peritoneal disease. METHODS:We compared rates of gastrointestinal perforation in patients with metastatic colorectal cancer and peritoneal disease receiving first-line chemotherapy ...

journal_title：World journal of gastroenterology

authors： Roohullah A,Wong HL,Sjoquist KM,Gibbs P,Field K,Tran B,Shapiro J,Mckendrick J,Yip D,Nott L,Gebski V,Ng W,Chua W,Price T,Tebbutt N,Chantrill L

更新日期：2015-05-07 00:00:00

abstract：:Angiosarcoma is a rare primary malignant neoplasm of the liver with a poor prognosis. Here, we report a case of a patient with a ruptured hepatic angiosarcoma which was treated by emergency catheter-directed embolization, followed by left-sided hemihepatectomy. ...

journal_title：World journal of gastroenterology

authors： Leowardi C,Hormann Y,Hinz U,Wente MN,Hallscheidt P,Flechtenmacher C,Buchler MW,Friess H,Schwarzbach MH

更新日期：2006-02-07 00:00:00

abstract：:Several drugs are used in the treatment of irritable bowel syndrome (IBS) but all have side effects and variable efficacy. Considering the role of the gut-brain axis, immune, neural, and endocrine pathways in the pathogenesis of IBS and possible beneficial effects of benzodiazepines (BZD) in this axis, the present sys...

journal_title：World journal of gastroenterology

authors： Salari P,Abdollahi M

更新日期：2011-10-14 00:00:00

abstract：:The diagnosis of early gastric cancer (EGC) is of great interest because its endoscopic and surgical treatment presents the best chance for a cure. With technical development, endoscopic submucosal dissection (ESD) has been widely performed for the curative treatment of EGC in Korea. Multinational studies of ESD for E...

journal_title：World journal of gastroenterology

authors： Cho WY,Cho JY,Chung IK,Kim JI,Jang JS,Kim JH

更新日期：2011-06-07 00:00:00

abstract：AIM:To investigate the association between adiponectin levels and risk of colorectal adenoma and cancer (early and advanced). METHODS:A cross-sectional study in a cohort of hospital-based patients was conducted between January 2004 and March 2006 at Yamagata University Hospital. Male subjects, who had colorectal tumor...

journal_title：World journal of gastroenterology

authors： Otake S,Takeda H,Fujishima S,Fukui T,Orii T,Sato T,Sasaki Y,Nishise S,Kawata S

更新日期：2010-03-14 00:00:00

abstract：AIM:To investigate the relationship between autophagy and perineural invasion (PNI), clinical features, and prognosis in patients with pancreatic cancer. METHODS:Clinical and pathological data were retrospectively collected from 109 patients with pancreatic ductal adenocarcinoma who underwent radical resection at the ...

journal_title：World journal of gastroenterology

authors： Yang YH,Liu JB,Gui Y,Lei LL,Zhang SJ

更新日期：2017-10-28 00:00:00

abstract：AIM:To describe the significant over-expression of fibroblast growth factor receptor 3 (FGFR3), which is a signal transduction and cell proliferation related gene in hepatocellular carcinoma (HCC). METHODS:Following DNA microarray, Northern blot and quantitative real-time PCR were employed to confirm FGFR3 expression ...

journal_title：World journal of gastroenterology

authors： Qiu WH,Zhou BS,Chu PG,Chen WG,Chung C,Shih J,Hwu P,Yeh C,Lopez R,Yen Y

更新日期：2005-09-14 00:00:00

abstract：AIM:To evaluate prospectively usefulness of fecal lactoferrin (Lf) and fecal hemoglobin (Hb) in the diagnosis of colorectal diseases. METHODS:Fecal Lf and Hb were measured using ELISA in 872 patients before they underwent colorectal endoscopy. RESULTS:Lf was positive in 18 (50%) of 36 patients with colorectal cancer,...

journal_title：World journal of gastroenterology

authors： Hirata I,Hoshimoto M,Saito O,Kayazawa M,Nishikawa T,Murano M,Toshina K,Wang FY,Matsuse R

更新日期：2007-03-14 00:00:00

abstract：BACKGROUND:Accumulating evidence has revealed that several long non-coding ribonucleic acids (lncRNAs) are crucial in the progress of hepatocellular carcinoma (HCC). AIM:To classify a long non-coding RNA, i.e., lncRNA W5, and to determine the clinical significance and potential roles of lncRNA W5 in HCC. METHODS:The ...

journal_title：World journal of gastroenterology

authors： Lei GL,Fan HX,Wang C,Niu Y,Li TL,Yu LX,Hong ZX,Yan J,Wang XL,Zhang SG,Ren MJ,Yang PH

更新日期：2021-01-07 00:00:00

abstract：:To review the inhibitory effect of preventive approaches on recurrence after operation in patients with hepatocellular carcinoma (HCC), we summarized all available publications reporting randomized control trial indexed in PubMed. The treatment approaches presented above included pre-operative transcatheter arterial c...

journal_title：World journal of gastroenterology

authors： Sun HC,Tang ZY

更新日期：2003-04-01 00:00:00

abstract：AIM:To investigate the effect of bile acid on the expression of histidine decarboxylase (HDC), which is a major enzyme involved in histamine production, and gene expression of gastric transcription factors upon cooperative activation. METHODS:HDC expression was examined by immunohistochemistry, reverse transcriptase p...

journal_title：World journal of gastroenterology

authors： Ku HJ,Kim HY,Kim HH,Park HJ,Cheong JH

更新日期：2014-01-07 00:00:00

abstract：AIM:To unravel the differences between systematic inflammatory response syndrome (SIRS) of acute pancreatitis compared to the same syndrome in sepsis. METHODS:Twenty-five patients were enrolled, 12 with sepsis and 13 acute pancreatitis. After diagnosis 20 mL blood was sampled. Half were assayed for isolation of monocy...

journal_title：World journal of gastroenterology

authors： Koussoulas V,Tzivras M,Karagianni V,Spyridaki E,Plachouras D,Giamarellou H,Giamarellos-Bourboulis EJ

更新日期：2006-11-07 00:00:00

abstract：AIM:To describe the learning curves of hand-assisted laparoscopic D2 radical gastrectomy (HALG) for the treatment of gastric cancer. METHODS:The HALG surgical procedure consists of three stages: surgery under direct vision via the port for hand assistance, hand-assisted laparoscopic surgery, and gastrointestinal tract...

journal_title：World journal of gastroenterology

authors： Gong JQ,Cao YK,Wang YH,Zhang GH,Wang PH,Luo GD

更新日期：2015-02-07 00:00:00

abstract：AIM:To explore molecular mechanism of nicotinamide adenine dinucleotide (NADH) antagonization against X-ray induced L02 cells damage. METHODS:L02 liver cells were cultured in RPMI 1640, exposed to X-ray irradiation and continued to culture in the presence or absence of NADH. Cellular viability was analyzed by routine ...

journal_title：World journal of gastroenterology

authors： Liu FQ,Zhang JR

更新日期：2003-08-01 00:00:00

abstract：:Proton pump inhibitors (PPIs) represent a milestone in the treatment of acid-related diseases, and are the mainstay in preventing upper gastrointestinal bleeding in high-risk patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin. However, this beneficial effect does not extend to the ...

journal_title：World journal of gastroenterology

authors： Lué A,Lanas A

更新日期：2016-12-28 00:00:00

abstract：AIM:To investigate the clinical utility of biological age (BA) measurement in screening colonoscopy for the detection of colorectal adenomas in the average-risk population. METHODS:A consecutive series of asymptomatic subjects aged ≥ 30 years who underwent colonoscopy in routine check-ups were enrolled. Colorectal ade...

journal_title：World journal of gastroenterology

authors： Kim SJ,Kim BJ,Kang H

更新日期：2017-10-07 00:00:00

abstract：:Malignant gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors originating from the wall of the gastrointestinal tract. Their coexistence with other tumors originating from other germ layers is unique. We have reported a case of a 63-year-old GIST patient presenting as an epigastric mass associated with ...

journal_title：World journal of gastroenterology

authors： Jaworski R,Jastrzebski T,Swierblewski M,Drucis K,Kobierska-Gulida G

更新日期：2006-01-28 00:00:00

abstract：AIM:To evaluate the effects of omeprazole on gastric mechanosensitivity in humans. METHODS:A double lumen polyvinyl tube with a plastic bag was introduced into the stomach of healthy volunteers under fluorography and connected to a barostat device. Subjects were then positioned so they were sitting comfortably, and th...

journal_title：World journal of gastroenterology

authors： Iida A,Kaneko H,Konagaya T,Funaki Y,Tokudome K,Izawa S,Tamura Y,Mizuno M,Ogasawara N,Sasaki M,Kasugai K

更新日期：2012-10-21 00:00:00

abstract：AIM:To identify the prevalence of hepatitis B e antigen (HBeAg) and to assess the association of hepatitis B virus (HBV) core promoter mutations and viral load in Indonesian patients. METHODS:Sixty-four patients with chronic hepatitis, 65 with liver cirrhosis and 50 with hepatocellular carcinoma were included in this ...

journal_title：World journal of gastroenterology

authors： Utama A,Siburian MD,Purwantomo S,Intan MD,Kurniasih TS,Gani RA,Achwan WA,Arnelis,Lelosutan SA,Lukito B,Harmono T,Zubir N,Julius,Soemohardjo S,Lesmana LA,Sulaiman A,Tai S

更新日期：2011-02-14 00:00:00