X-ray induced L02 cells damage rescued by new anti-oxidant NADH.

abstract：AIM:To determine whether IFN-alpha is the agent that turns a slightly effective treatment (radiochemotherapy) into a potent therapy, we tested IFN-alpha for its synergistic properties. METHODS:Eight pancreatic carcinoma cell lines were treated with the single agents and combinations of these. The role of IFN-alpha reg...

journal_title：World journal of gastroenterology

authors： Ma JH,Patrut E,Schmidt J,Knaebel HP,Büchler MW,Märten A

更新日期：2005-03-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common primary cancers in the world. Surgery is the gold standard for treatment of patients with HCC. Recurrence and metastasis are the major obstacles to further improve the prognosis of HCC. Most recurrences are intrahepatic. However, 30% of the recurrences are extra...

journal_title：World journal of gastroenterology

authors： Sun L,Guan YS,Pan WM,Chen GB,Luo ZM,Wu H

更新日期：2007-10-28 00:00:00

abstract：AIM:To investigate the relationship between certain biochemical parameters of lipid metabolism in the serum and steatosis in the liver. METHODS:The grade of steatosis (0-3) and histological activity index (HAI, 0-18) in liver biopsy specimens were correlated with serum alanine aminotransferase (ALT), total cholesterol...

journal_title：World journal of gastroenterology

authors： Jármay K,Karácsony G,Nagy A,Schaff Z

更新日期：2005-11-07 00:00:00

abstract：AIM:To assess CD163 expression in plasma and peripheral blood and analyze its association with disease in acute-on-chronic hepatitis B liver failure (ACHBLF) patients. METHODS:A retrospective study was conducted from January 1, 2011 to January 1, 2012. Forty patients with ACHBLF (mean age 44.48 ± 12.28 years, range 18...

journal_title：World journal of gastroenterology

authors： Ye H,Wang LY,Zhao J,Wang K

更新日期：2013-05-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and leading cause of death among patients with cirrhosis. Treatment guidelines are based according to the Barcelona Clinic Liver Cancer staging system. The choice among therapeutic options that include liver resection, liver transplantation, loco...

journal_title：World journal of gastroenterology

authors： Tabrizian P,Roayaie S,Schwartz ME

更新日期：2014-08-14 00:00:00

abstract：AIM:To investigate the effects of adeno-associated virus (AAV) mediated expression of human interferon-gamma for gene therapy in experimental hepatic fibrosis in vitro and in vivo. METHODS:We constructed the recombinant AAV encoding human INF-gamma (rAAV- INF-gamma) and took the primary rat hepatic stellate cells and ...

journal_title：World journal of gastroenterology

authors： Chen M,Wang GJ,Diao Y,Xu RA,Xie HT,Li XY,Sun JG

更新日期：2005-07-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major causes of morbidity and mortality in patients with chronic liver disease. Transarterial chemoembolization (TACE) can significantly improve the survival rate of patients with HCC and is the first treatment choice for patients who are not suitable for surgical resection...

journal_title：World journal of gastroenterology

authors： Yang K,Zhang XM,Yang L,Xu H,Peng J

更新日期：2016-05-28 00:00:00

abstract：AIM:To retrospectively evaluate the vaccination-induced anti-HBs seroconversion rates in treatment-naive and treatment-experienced chronic hepatitis C (CHC) patients. Also to prospectively evaluate the seroconversion rates in CHC patients during pegylated interferon (PEG) plus ribavirin (RIB) treatment. METHODS:Sevent...

journal_title：World journal of gastroenterology

authors： Elefsiniotis IS,Vezali E,Kamposioras K,Pantazis KD,Tontorova R,Ketikoglou I,Moulakakis A,Saroglou G

更新日期：2006-07-21 00:00:00

abstract：AIM:To evaluate the impact of glycemic control and nutritional status after total pancreatectomy (TP) on complications, tumor recurrence and overall survival. METHODS:Retrospective records of 52 patients with pancreatic tumors who underwent TP were collected from 2007 to 2015. A series of clinical parameters collected...

journal_title：World journal of gastroenterology

authors： Shi HJ,Jin C,Fu DL

更新日期：2017-01-14 00:00:00

abstract：AIM:To establish whether there are fundamental differences in the biochemistries of adenocarcinomas of the gastroesophageal junction (GEJ) and the squamous cell carcinomas of the lower third of the esophagus (LTE). METHODS:Between February 1, 1997 and February 1, 2000, we obtained tissue samples at the moment of resec...

journal_title：World journal of gastroenterology

authors： Altorjay A,Paal B,Sohar N,Kiss J,Szanto I,Sohar I

更新日期：2005-10-07 00:00:00

abstract：:Proteus syndrome is an extremely rare congenital disorder that produces multifocal overgrowth of tissue. This report presents a surgical case of a large lipoma in the abdominal wall of a patient with Proteus syndrome. She was diagnosed with Proteus syndrome based on certain diagnostic criteria. The neoplasm increased ...

journal_title：World journal of gastroenterology

authors： Nakayama Y,Kusuda S,Nagata N,Yamaguchi K

更新日期：2009-07-14 00:00:00

abstract：AIM:To explore the correlation between expression of somatostatin (SS), gastrin (GAS) and cell apoptosis regulation gene bcl-2/bax in large intestine carcinoma. METHODS:Sixty-two large intestine cancer tissue samples were randomly and retrospectively selected from patients with large intestine carcinoma. Immunohistoch...

journal_title：World journal of gastroenterology

authors： Mao JD,Wu P,Xia XH,Hu JQ,Huang WB,Xu GQ

更新日期：2005-02-07 00:00:00

abstract：AIM:To study the viscoelastic properties of human hepatocytes and hepatocellular carcinoma (HCC) cells under cytoskeletal perturbation, and to further to study the viscoelastic properties and the adhesive properties of mouse hepatoma cells (HTC) in different cell cycle. METHODS:Micropipette aspiration technique was ad...

journal_title：World journal of gastroenterology

authors： Zhang G,Long M,Wu ZZ,Yu WQ

更新日期：2002-04-01 00:00:00

abstract：AIM:To evaluate the effect of the shunting branch of the portal vein (PV) (left or right) and the initial stent position (optimal or suboptimal) of a transjugular intrahepatic portosystemic shunt (TIPS). METHODS:We retrospectively reviewed 307 consecutive cirrhotic patients who underwent TIPS placement for variceal bl...

journal_title：World journal of gastroenterology

authors： Bai M,He CY,Qi XS,Yin ZX,Wang JH,Guo WG,Niu J,Xia JL,Zhang ZL,Larson AC,Wu KC,Fan DM,Han GH

更新日期：2014-01-21 00:00:00

abstract：AIM:To evaluate the feasibility of using multiphoton microscopy (MPM) to assess a tumor regression grading (TRG) system. METHODS:Fresh specimens from seven patients with colorectal carcinoma undergoing neoadjuvant radiochemotherapy at the Fujian Medical University Union Hospital were obtained immediately after proctec...

journal_title：World journal of gastroenterology

authors： Li LH,Chen ZF,Wang XF,Zhuo SM,Li HS,Jiang WZ,Guan GX,Chen JX

更新日期：2015-04-14 00:00:00

abstract：:Hepatocellular carcinomas (HCCs) frequently recur despite initial successful surgical resection or local ablation therapy. Diagnostic methods for small HCCs have improved with the introduction of gadoxetic acid-enhanced liver magnetic resonance imaging and diffusion-weighted imaging (DWI). Currently, sub-centimeter re...

journal_title：World journal of gastroenterology

authors： Lee MW,Lim HK

更新日期：2018-12-14 00:00:00

abstract：:Adult to adult living donor liver transplantation (AALDLT) was first preformed in the United States in 1997. The procedure was rapidly integrated into clinical practice, but in 2002, possibly due to the first widely publicized donor death, the number of living liver donors plummeted. The number of donors has since rea...

journal_title：World journal of gastroenterology

authors： Carlisle EM,Testa G

更新日期：2012-12-14 00:00:00

abstract：AIM:To compare the results for endoscopic ultrasound (EUS)-guided drainage of clear fluid pancreatic pseudocysts with the results for abscess drainage. METHODS:All patients referred for endoscopic drainage of a fluid collection were prospectively included. The outcome was recorded. RESULTS:Altogether 26 pseudocysts o...

journal_title：World journal of gastroenterology

authors： Sadik R,Kalaitzakis E,Thune A,Hansen J,Jönson C

更新日期：2011-01-28 00:00:00

abstract：:Treatment of chronic pancreatitis has been exclusively surgical for a long time. Recently, endoscopic therapy has become widely used as a primary therapeutic option. Initially performed for drainage of pancreatic cysts and pseudocysts, endoscopic treatments were adapted to biliary and pancreatic ducts stenosis. Pancre...

journal_title：World journal of gastroenterology

authors： Heyries L,Sahel J

更新日期：2007-12-14 00:00:00

abstract：AIM:To study the expression levels of E- selectin, integrin beta1 and immunoglobulin superfamily member-intercellular adhesion molecule-1 (ICAM-1) in human gastric carcinoma cells, and to explore the relationship between these three kinds of cell adhesion molecules and gastric carcinoma. METHODS:The serum contents of ...

journal_title：World journal of gastroenterology

authors： Ke JJ,Shao QS,Ling ZQ

更新日期：2006-06-14 00:00:00

abstract：:Clostridium septicum (C. septicum) gas gangrene is well documented in the literature, typically in the setting of trauma or immunosuppression. In this paper, we report a unique case of spontaneous clostridial myonecrosis in a patient with Crohn's disease and sulfasalazine-induced neutropenia. The patient presented wit...

journal_title：World journal of gastroenterology

authors： Kiel N,Ho V,Pascoe A

更新日期：2011-09-07 00:00:00

abstract：AIM:To investigate the efficacy of neoadjuvant chemoradiotherapy (NACRT) for resectability of locally advanced gastric cancer (LAGC). METHODS:Between November 2007 and January 2014, 29 patients with LAGC (clinically T3 with distal esophagus invasion/T4 or bulky regional node metastasis) that were treated with NACRT fo...

journal_title：World journal of gastroenterology

authors： Kim MS,Lim JS,Hyung WJ,Lee YC,Rha SY,Keum KC,Koom WS

更新日期：2015-03-07 00:00:00

abstract：:Over the last 15 years, there have been major advances in the multimodal treatment of gastric cancer, in large part due to several phase III studies showing the treatment benefits of neoadjuvant and adjuvant chemotherapy and chemoradiation protocols. The objective of this editorial is to review the current high-level ...

journal_title：World journal of gastroenterology

authors： Choi AH,Kim J,Chao J

更新日期：2015-06-28 00:00:00

abstract：:AIM:To study the peripheral mechanism of the inhibitory effect of intra-third ventricular administration (icv) of histamine (HA) on gastric acid secretion in rats.METHODS:Gastric acid was continuously washed with 37&mgr; saline by a perfusion pump in male adrenalectomized SD rats. Drugs were injected intravenously (iv...

journal_title：World journal of gastroenterology

authors： Zhang ZF,Wang ZL,Lu GQ

更新日期：1998-06-01 00:00:00

abstract：:Of the diverse biological agents used for patients with ulcerative colitis, the anti-tumor necrosis factor-α agents infliximab and adalimumab have been used in large-scale clinical trials and are currently widely used in the treatment of inflammatory bowel disease patients. Recent studies have indicated that golimumab...

journal_title：World journal of gastroenterology

authors： Seo GS,Chae SC

更新日期：2014-10-07 00:00:00

abstract：:Helicobacter pylori (H pylori) infection is the main cause of gastritis, gastroduodenal ulcer disease, and gastric cancer. After more than 20 years of experience in H pylori treatment, in my opinion, the ideal regimen to treat this infection is still to be found. Currently, apart from having to know first-line eradica...

journal_title：World journal of gastroenterology

authors： Gisbert JP

更新日期：2008-09-21 00:00:00

abstract：:Studies on rodents and humans demonstrate an inherited predisposition to hepatocellular carcinoma (HCC). Analysis of the molecular alterations involved in the acquisition of a phenotype resistant or susceptible to hepatocarcinogenesis showed a deregulation of G1 and S phases in HCC of genetically susceptible F344 rats...

journal_title：World journal of gastroenterology

authors： Feo F,Frau M,Pascale RM

更新日期：2008-11-21 00:00:00

abstract：AIM:We aimed to observe the expression of extracellular matrix (ECM) and cellular adhesion molecules (CAM) in cirrhotic liver tissues after hepatitis C virus (HCV) infection. METHODS:Twelve patients with post HCV inflammatory liver cirrhosis were selected to evaluate their liver function and other virological, patholo...

journal_title：World journal of gastroenterology

authors： Xu X,Li YM,Ji H,Hou CZ,Cheng YB,Ma FP

更新日期：2005-04-14 00:00:00

abstract：AIM:To clarify the strategy for early diagnosis of pancreaticobiliary maljunction (PBM) without biliary dilatation and to pathologically examine gallbladder before cancer develops. METHODS:The anatomy of the union of the pancreatic and bile ducts was assessed by using endoscopic retrograde cholangiopancreatography (ER...

journal_title：World journal of gastroenterology

authors： Takuma K,Kamisawa T,Tabata T,Hara S,Kuruma S,Inaba Y,Kurata M,Honda G,Tsuruta K,Horiguchi S,Igarashi Y

更新日期：2012-07-14 00:00:00

abstract：AIM:To assess the efficiency of endoscopic trans-esophageal submucosal tunneling surgery (EESTS) technique for diseases located around the aorta ventralis. METHODS:Nine pigs were assigned to EESTs. The procedures were as follows: First, a long esophageal submucosal tunnel was established. Second, full-thickness myotom...

journal_title：World journal of gastroenterology

authors： Xiong Y,Chen QQ,Chai NL,Jiao SC,Ling Hu EQ

更新日期：2019-01-07 00:00:00