Connective tissue growth factor is overexpressed in human hepatocellular carcinoma and promotes cell invasion and growth.

abstract：AIM:To determine the incidence of hepatocellular carcinoma (HCC) and the impact of HCC surveillance on early diagnosis and survival of cirrhotic outpatients. METHODS:In this retrospective cohort study, cirrhotic outpatients undergoing HCC surveillance between March 2005 and March 2014 were analyzed. Exclusion criteria...

journal_title：World journal of gastroenterology

authors： Appel-da-Silva MC,Miozzo SA,Dossin IA,Tovo CV,Branco F,de Mattos AA

更新日期：2016-12-14 00:00:00

abstract：AIM:To evaluate retrospectively the correlation between enhancement patterns on dynamic computed tomography (CT) and angiogenesis and fibrosis in pancreatic adenocarcinoma. METHODS:Twenty-three patients with pancreatic adenocarcinoma underwent dynamic CT and tumor resection. In addition to the absolute and relative en...

journal_title：World journal of gastroenterology

authors： Hattori Y,Gabata T,Matsui O,Mochizuki K,Kitagawa H,Kayahara M,Ohta T,Nakanuma Y

更新日期：2009-07-07 00:00:00

abstract：AIM:To clarify the clinicopathological characteristics of small and large early invasive colorectal cancers (EI-CRCs), and to determine whether malignancy grade depends on size. METHODS:A total of 583 consecutive EI-CRCs treated by endoscopic mucosal resection or surgery at the National Cancer Center Hospital between ...

journal_title：World journal of gastroenterology

authors： Matsuda T,Saito Y,Fujii T,Uraoka T,Nakajima T,Kobayashi N,Emura F,Ono A,Shimoda T,Ikematsu H,Fu KI,Sano Y,Fujimori T

更新日期：2009-06-14 00:00:00

abstract：AIM:To evaluate the expressions of apoptotic signal proteins FADD, TRADD, FasL, Fas, and NFkappaB in gastric carcinoma tissues and their clinical significance. METHODS:Western blot immune trace method was adopted to detect the expressions of apoptotic signal proteins FADD, TRADD, FasL, Fas, and NFkappaB in 55 tissue s...

journal_title：World journal of gastroenterology

authors： Zhao XH,Gu SZ,Tian HG,Quan P,Pan BR

更新日期：2005-07-07 00:00:00

abstract：:Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by the intake of pyrrolizidine alkaloids (PAs). To date, PAs-induced HSOS has not been extensively studied. In view of the difference in etiology of HSOS between the West and China, clinical profiles, imaging findings, treatment, and outcomes of HSOS associa...

journal_title：World journal of gastroenterology

authors： Yang XQ,Ye J,Li X,Li Q,Song YH

更新日期：2019-07-28 00:00:00

abstract：AIM:To investigate the effect of moxibustion on intestinal flora and release of interleukin-12 (IL-12) and tumor necrosis factor-α (TNF-α) from the colon in rat with ulcerative colitis (UC). METHODS:A rat model of UC was established by local stimulation of the intestine with supernatant from colonic contents harvested...

journal_title：World journal of gastroenterology

authors： Wang XM,Lu Y,Wu LY,Yu SG,Zhao BX,Hu HY,Wu HG,Bao CH,Liu HR,Wang JH,Yao Y,Hua XG,Guo HY,Shen LR

更新日期：2012-12-14 00:00:00

abstract：:The evasion from controlled cell death induction has been considered as one of the hallmarks of cancer cells. Defects in cell death signaling are a fundamental phenomenon in colorectal cancer. Nearly any non-invasive cancer treatment finally aims to induce cell death. However, apoptosis resistance is the major cause f...

journal_title：World journal of gastroenterology

authors： Koehler BC,Jäger D,Schulze-Bergkamen H

更新日期：2014-02-28 00:00:00

abstract：AIM:To review the surgical outcomes in terms of the surgical indications and relevant prognostic factors. METHODS:Sixteen patients underwent therapeutic lung surgery between March 1999 and May 2006. The observation period was terminated on May 31, 2007. The surgical outcomes and the clinicopathological factors were co...

journal_title：World journal of gastroenterology

authors： Kwon JB,Park K,Kim YD,Seo JH,Moon SW,Cho DG,Kim YW,Kim DG,Yoon SK,Lim HW

更新日期：2008-10-07 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) has become a major cause of chronic liver disease. The Chinese herbal medicine (CHM) Dachaihu decoction (DCHD) has been proved to treat NAFLD with good efficacy in previous studies. Based on the TCM principle of formula formation, we divided DCHD into soothing liver ...

journal_title：World journal of gastroenterology

authors： Yang JM,Sun Y,Wang M,Zhang XL,Zhang SJ,Gao YS,Chen L,Wu MY,Zhou L,Zhou YM,Wang Y,Zheng FJ,Li YH

更新日期：2019-09-14 00:00:00

abstract：:Colorectal cancer is a major cause of cancer-related death in many countries. Colorectal carcinogenesis is a stepwise process which, from normal mucosa leads to malignancy. Many factors have been shown to influence this process, however, at present, several points remain obscure. In recent years some hypotheses have b...

journal_title：World journal of gastroenterology

authors： Mariani F,Sena P,Roncucci L

更新日期：2014-08-07 00:00:00

abstract：:Over the last 15 years, there have been major advances in the multimodal treatment of gastric cancer, in large part due to several phase III studies showing the treatment benefits of neoadjuvant and adjuvant chemotherapy and chemoradiation protocols. The objective of this editorial is to review the current high-level ...

journal_title：World journal of gastroenterology

authors： Choi AH,Kim J,Chao J

更新日期：2015-06-28 00:00:00

abstract：:Acute liver failure is a rare presentation of hematologic malignancy. Acute on chronic liver failure (ACLF) is a newly recognized clinical entity that describes acute hepatic decompensation in persons with preexisting liver disease. Diffuse large B-cell lymphoma (DLBCL) is an aggressive non-Hodgkin's lymphoma (NHL) wi...

journal_title：World journal of gastroenterology

authors： Siba Y,Obiokoye K,Ferstenberg R,Robilotti J,Culpepper-Morgan J

更新日期：2014-11-28 00:00:00

abstract：AIM:To highlight magnetic resonance enterography (MRE) for diagnosis of patients with refractory iron deficiency anemia and normal endoscopy results. METHODS:Fifty-three patients diagnosed with iron deficiency anemia refractory to treatment and normal gastroscopy and colonoscopy results were admitted to this prospecti...

journal_title：World journal of gastroenterology

authors： Cengic I,Tureli D,Aydin H,Bugdayci O,Imeryuz N,Tuney D

更新日期：2014-10-14 00:00:00

abstract：AIM:To identify the incidence and etiology of anemia after gastrectomy in patients with long-term follow-up after gastrectomy for early gastric cancer. METHODS:The medical records of those patients with early gastric adenocarcinoma who underwent curative gastrectomy between January 2006 and October 2007 were reviewed....

journal_title：World journal of gastroenterology

authors： Lim CH,Kim SW,Kim WC,Kim JS,Cho YK,Park JM,Lee IS,Choi MG,Song KY,Jeon HM,Park CH

更新日期：2012-11-14 00:00:00

abstract：:A female patient with anemia and hypoalbuminemia was admitted to our hospital due to an over 20-year history of recurrent dizziness, fatigue and ankle edema. She was diagnosed as multiple chronic non-specific ulcer of the small intestine characterized by non-specific histology and persistent gastrointestinal bleeding....

journal_title：World journal of gastroenterology

authors： Chen Y,Ma WQ,Chen JM,Cai JT

更新日期：2010-02-14 00:00:00

abstract：AIM:To retrospectively evaluate the imaging features of pancreatic intraductal papillary mucinous neoplasms (IPMNs) in multi-detector row computed tomography (MDCT). METHODS:A total of 20 patients with pathologically-confirmed intraductal papillary mucinous neoplasms (IPMNs) were included in this study. Axial MDCT ima...

journal_title：World journal of gastroenterology

authors： Tan L,Zhao YE,Wang DB,Wang QB,Hu J,Chen KM,Deng XX

更新日期：2009-08-28 00:00:00

abstract：AIM:To compare the therapeutic effects of proton pump inhibitors vs H₂ receptor antagonists for upper gastrointestinal bleeding in patients after successful endoscopy. METHODS:We searched the Cochrane library, MEDLINE, EMBASE and PubMed for randomized controlled trials until July 2014 for this study. The risk of bias ...

journal_title：World journal of gastroenterology

authors： Zhang YS,Li Q,He BS,Liu R,Li ZJ

更新日期：2015-05-28 00:00:00

abstract：:Although the lung is the major site for Mycobacterium tuberculosis infection, gastrointestinal involvement can be present as part of multiorgan disease process or, less commonly, can be seen as primary gastrointestinal tuberculosis. In the cases where the culture is negative, it can be difficult to differentiate tuber...

journal_title：World journal of gastroenterology

authors： Settbas Y,Alper M,Akcan Y,Gurbuz Y,Oksuz S

更新日期：2003-10-01 00:00:00

abstract：AIM:To assess the clinicopathological characteristics of duodenal well-differentiated endocrine tumors. METHODS:We examined clinicopathological characteristics in 11 consecutive patients with duodenal well-differentiated endocrine tumors treated by endoscopic therapy or surgery in our hospital from 1992 through 2007. ...

journal_title：World journal of gastroenterology

authors： Ishido K,Tanabe S,Higuchi K,Sasaki T,Katada C,Azuma M,Naruke A,Koizumi W,Mikami T

更新日期：2010-09-28 00:00:00

abstract：:Combined en bloc liver/pancreas transplantation (CLPT) was used primarily in the treatment of otherwise non-resectable upper abdominal malignancy. In fact, a more appropriate indication is in patients with liver disease and insulin-dependent diabetes mellitus (IDDM). Here, we report on two successful cases of CLPT at ...

journal_title：World journal of gastroenterology

authors： Chen ZS,Meng FY,Chen XP,Liu DG,Wei L,Jiang JP,Du DF,Zhang WJ,Ming CS,Gong NQ

更新日期：2009-05-28 00:00:00

abstract：BACKGROUND:At our academic tertiary care medical center, we have noted patients referred for endoscopic retrograde cholangiopancreatography (ERCP) who increasingly require advanced cannulation techniques. This trend is noted despite increased endoscopist experience and annual ERCP volume over the same period. AIM:To e...

journal_title：World journal of gastroenterology

authors： Barakat MT,Girotra M,Thosani N,Kothari S,Banerjee S

更新日期：2020-11-07 00:00:00

abstract：:Immunoglobulin G4-related sclerosing cholangitis (IgG4-SC) is frequently associated with type 1 autoimmune pancreatitis (AIP). Association with AIP can be utilized in the diagnosis of IgG4-SC. However, some cases of IgG4-SC are isolated from AIP, which complicates the diagnosis. Most of the reported cases of isolated ...

journal_title：World journal of gastroenterology

authors： Nakazawa T,Ikeda Y,Kawaguchi Y,Kitagawa H,Takada H,Takeda Y,Makino I,Makino N,Naitoh I,Tanaka A

更新日期：2015-01-28 00:00:00

abstract：:Cholangiocarcinoma is the second most common primary hepatic cancer. Despite advances in diagnostic techniques during the past decade, cholangiocarcinoma is usually encountered at an advanced stage. In this review, we describe the classification, diagnosis, and initial management of cholangiocarcinoma with obstructive...

journal_title：World journal of gastroenterology

authors： Tajiri T,Yoshida H,Mamada Y,Taniai N,Yokomuro S,Mizuguchi Y

更新日期：2008-05-21 00:00:00

abstract：:Innate lymphoid cells (ILCs) are defined as a distinct arm of innate immunity. According to their profile of secreted cytokines and lineage-specific transcriptional factors, ILCs can be categorized into the following three groups: group 1 ILCs (including natural killer (NK) cells and ILC1s) are dependent on T-bet and ...

journal_title：World journal of gastroenterology

authors： Shen Y,Li J,Wang SQ,Jiang W

更新日期：2018-05-14 00:00:00

abstract：AIM:Small intestinal bacterial overgrowth (SIBO) may contribute to the appearance of several gastrointestinal nonspecific symptoms. Acute diverticulitis is affected by some similar symptoms and bacterial colonic overgrowth. We assessed the prevalence of SIBO in acute uncomplicated diverticulitis and evaluated its influ...

journal_title：World journal of gastroenterology

authors： Tursi A,Brandimarte G,Giorgetti GM,Elisei W

更新日期：2005-05-14 00:00:00

abstract：:A rare case of multiple small bowel ruptures due to ischemic enteritis (ISE) is reported. The patient was admitted to the hospital with acute abdominal pain followed by bloody diarrhoeas. Preoperative colonoscopic findings were similar to those presented in Crohn's disease. Intraoperatively, ischemic lesions and multi...

journal_title：World journal of gastroenterology

authors： Delikoukos S,Christodoulidis G,Zacharoulis D,Poultsidi A,Hatzitheofilou C

更新日期：2006-07-14 00:00:00

abstract：:We here report a case of a 18-year-old man with a history of recurrent abdominal pain and a previous episode of severe acute pancreatitis. Abdominal ultrasonography, contrast enhanced multislice computer tomography, endoscopic retrograde cholangiopancreatography, endoscopic ultrasonography and magnetic resonance imagi...

journal_title：World journal of gastroenterology

authors： Guarise A,Faccioli N,Ferrari M,Romano L,Parisi A,Falconi M

更新日期：2006-03-14 00:00:00

abstract：AIM:To evaluate the association between HLA-DRB1 alleles and Han and Uyghur ulcerative colitis (UC) patients residing in the Xinjiang Uyghur Autonomous Region of China. METHODS:In this study, 102 UC patients (53 Han including 22 men and 31 women, and 49 Uyghur patients including 25 men and 24 women; aged 48.07 ± 15.83...

journal_title：World journal of gastroenterology

authors： Aheman A,Gao F,Kuerbanjiang A,Li YX,Abuduhadeer M

更新日期：2013-05-07 00:00:00

abstract：AIM:To analyze, retrospectively in a population-based study, the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS:All rectal carcinomas diagnosed during 1998 to 2000 and initially treated w...

journal_title：World journal of gastroenterology

authors： Bakx R,Visser O,Josso J,Meijer S,Slors JF,van Lanschot JJ

更新日期：2008-10-21 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) has been recognized as a major health burden. The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity, unhealthy dietary pattern, and sedentary lifestyle. The efficacy and safety profile of pharmacotherapy in the treatment of NAFLD remains uncertai...

journal_title：World journal of gastroenterology

authors： Zelber-Sagi S,Ratziu V,Oren R

更新日期：2011-08-07 00:00:00