Inflammatory pathways in the early steps of colorectal cancer development.

abstract：AIM:To evaluate safety and effect on hepatitis B virus (HBV) suppression of a long-term treatment with lamivudine (LAM) at standard (100 mg/d) or double (200 mg/d) dose in chronic hepatitis B. METHODS:This was a case study with matched controls (1:3) in patients with chronic hepatitis B with anti-HBe antibodies. RESU...

journal_title：World journal of gastroenterology

authors： Stornaiuolo G,Stanzione M,Brancaccio G,Cuomo G,Precone V,Di Biase S,Felaco FM,Piccinino F,Gaeta GB

更新日期：2007-11-14 00:00:00

abstract：BACKGROUND:At our academic tertiary care medical center, we have noted patients referred for endoscopic retrograde cholangiopancreatography (ERCP) who increasingly require advanced cannulation techniques. This trend is noted despite increased endoscopist experience and annual ERCP volume over the same period. AIM:To e...

journal_title：World journal of gastroenterology

authors： Barakat MT,Girotra M,Thosani N,Kothari S,Banerjee S

更新日期：2020-11-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) remains to be one of the top causing cancer-related deaths today. The majority of HCC cases are reported to be the result of chronic hepatitis B virus (HBV) infection. Current treatments for HBV-related HCC revolve around the use of drugs to inhibit viral replication, as a high level of ...

journal_title：World journal of gastroenterology

authors： Tan YL,Chen WN

更新日期：2014-05-28 00:00:00

abstract：AIM:To study the expression of trefoil factor 1 (TFF1) and TFF2 in precancerous condition and gastric cancer and to explore the relationship between TFFs and tumorigenesis, precancerous condition and gastric cancer. METHODS:The expression of TFF1 and TFF2 was immunohistochemically analyzed in paraffin-embedded samples...

journal_title：World journal of gastroenterology

authors： Shi SQ,Cai JT,Yang JM

更新日期：2006-05-21 00:00:00

abstract：AIM:To longitudinally investigate cytokine gene expression and protein levels in Th17 and Treg cells, to observe T-cell phenotypes during hepatitis B virus (HBV)-related acute-on-chronic liver failure (ACHBLF) and to analyze changes in Th17 and Treg phenotypes during disease progression. METHODS:We measured the expres...

journal_title：World journal of gastroenterology

authors： Liang XS,Li CZ,Zhou Y,Yin W,Liu YY,Fan WH

更新日期：2014-07-14 00:00:00

abstract：BACKGROUND:The formation of liver fibrosis is mainly caused by the activation of hepatic stellate cells (HSCs) and the imbalance of extracellular matrix (ECM) production and degradation. The treatment of liver fibrosis mainly includes removing the cause, inhibiting the activation of HSCs, and inhibiting inflammation. N...

journal_title：World journal of gastroenterology

authors： Zhang YZ,Yao JN,Zhang LF,Wang CF,Zhang XX,Gao B

更新日期：2019-06-28 00:00:00

abstract：BACKGROUND:Stress-related gastric mucosal damage or ulcer remains an unsolved issue for critically ill patients. Stress ulcer prophylaxis has been part of routine intensive care, but uncertainty and controversy still exist. Co-secreted with mucins, intestinal trefoil factor (ITF) is reported to promote restitution and ...

journal_title：World journal of gastroenterology

authors： Huang Y,Wang MM,Yang ZZ,Ren Y,Zhang W,Sun ZR,Nie SN

更新日期：2020-12-28 00:00:00

abstract：:We describe herein a 68-year-old woman who was diagnosed with a quite rare entity of intraductal papillary mucinous neoplasms (IPMNs) occurring simultaneously in the left lateral lobe of liver and the tail of pancreas. Abdominal computed tomography and magnetic resonance cholangiopancreatography showed a cystic dilata...

journal_title：World journal of gastroenterology

authors： Xu XW,Li RH,Zhou W,Wang J,Zhang RC,Chen K,Mou YP

更新日期：2012-11-28 00:00:00

abstract：:Increased numbers of mucosa-associated Escherichia coli are observed in both of the major inflammatory bowel diseases, Crohn d' disease (CD) and ulcerative colitis (UC). A potential pathophysiological link between the presence of pathogenic invasive bacteria and genetic host susceptibility of patients with ileal CD is...

journal_title：World journal of gastroenterology

authors： Barnich N,Darfeuille-Michaud A

更新日期：2007-11-14 00:00:00

abstract：AIM:To identify esophageal cancer related gene2 (ECRG2) associated proteins and their possible interactions with ECRG2 gene. METHODS:In the yeast forward two-hybrid system, ECRG2 was fused with the DNA-binding domain (DBD) of Gal4 and human fetal liver cDNA library was fused with the transcriptional activation domain ...

journal_title：World journal of gastroenterology

authors： Cui YP,Wang JB,Zhang XY,Bi MX,Guo LP,Lu SH

更新日期：2003-09-01 00:00:00

abstract：AIM:To compare natural orifice transluminal endoscopic surgery (NOTES) vs standard laparoscopic ovariectomy in mini pigs with respect to technical aspects, complications and parameters of systemic inflammatory response. METHODS:This was a randomized, experimental, survival study. Ten female mini pigs underwent NOTES t...

journal_title：World journal of gastroenterology

authors： Martínek J,Ryska O,Filípková T,Doležel R,Juhas S,Motlík J,Holubová M,Nosek V,Rotnáglová B,Zavoral M,Ryska M

更新日期：2012-07-21 00:00:00

abstract：:Cystic dystrophy of the duodenal wall is a rare form of the disease which was described in 1970 by French authors who reported the presence of focal pancreatic disease localized in an area comprising the C-loop of the duodenum and the head of the pancreas. German authors have defined this area as a "groove". We report...

journal_title：World journal of gastroenterology

authors： Pezzilli R,Santini D,Calculli L,Casadei R,Morselli-Labate AM,Imbrogno A,Fabbri D,Taffurelli G,Ricci C,Corinaldesi R

更新日期：2011-10-21 00:00:00

abstract：:Ulcerative colitis (UC) is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum. The hallmark clinical symptom of UC is bloody diarrhea. The clinical course is marked by exacerbations and remissions, which may occur spontaneously or in response to treatment changes or intercurr...

journal_title：World journal of gastroenterology

authors： da Silva BC,Lyra AC,Rocha R,Santana GO

更新日期：2014-07-28 00:00:00

abstract：:Colorectal cancer is a major public health burden worldwide. There is clear-cut evidence that screening will reduce colorectal cancer mortality and the only contentious issue is which screening tool to use. Most evidence points towards screening with fecal occult blood testing. The immunochemical fecal occult blood te...

journal_title：World journal of gastroenterology

authors： McLoughlin RM,O'Morain CA

更新日期：2006-11-14 00:00:00

abstract：AIM:To investigate the diagnosis of nonalcoholic steatohepatitis (NASH) using contrast ultrasonography in the NASH rat model. METHODS:The liver in methionine choline-deficient diet (MCDD) rats, a NASH model constructed by feeding an MCDD, was examined by contrast ultrasonography at weeks 2, 4, 8, 12 and 16, with late ...

journal_title：World journal of gastroenterology

authors： Miyata Y,Miyahara T,Moriyasu F

更新日期：2011-10-07 00:00:00

abstract：AIM:To investigate the effects of osteopontin (OPN) gene expression knockdown on colon cancer Lovo cells in vitro. METHODS:Four candidate small interfering RNA (siRNA) constructs targeting the OPN gene and a scrambled control sequence (NC-siRNA) were synthesized and inserted into a pGPU6/GFP/Neo expression vector. Aft...

journal_title：World journal of gastroenterology

authors： Wu XL,Lin KJ,Bai AP,Wang WX,Meng XK,Su XL,Hou MX,Dong PD,Zhang JJ,Wang ZY,Shi L

更新日期：2014-08-14 00:00:00

abstract：AIM:To investigate the relationship between pathological oropharyngeal (OP) acid exposure and esophageal motility in patients with extra-esophageal syndromes. METHODS:In this prospective study we enrolled consecutive outpatients with extra-esophageal symptoms suspected to be related to gastroesophageal reflux disease ...

journal_title：World journal of gastroenterology

authors： Passaretti S,Mazzoleni G,Vailati C,Testoni PA

更新日期：2016-10-28 00:00:00

abstract：AIM:To investigate protective effects and molecular mechanisms of green tea polyphenols (GTP) on non-alcoholic fatty liver disease (NAFLD) in Zucker fatty (ZF) rats. METHODS:Male ZF rats were fed a high-fat diet (HFD) for 2 wk then treated with GTP (200 mg/kg) or saline (5 mL/kg) for 8 wk, with Zucker lean rat as thei...

journal_title：World journal of gastroenterology

authors： Tan Y,Kim J,Cheng J,Ong M,Lao WG,Jin XL,Lin YG,Xiao L,Zhu XQ,Qu XQ

更新日期：2017-06-07 00:00:00

abstract：AIM:To evaluate the diagnostic values of serum autoantibodies against matrix metalloproteinase-7 (MMP-7) in patients with esophageal squamous cell carcinoma (ESCC). METHODS:The MMP-7 cDNA was cloned from ESCC tissues, and MMP-7 was expressed and purified from a prokaryotic system. MMP-7 autoantibodies were then measur...

journal_title：World journal of gastroenterology

authors： Zhou JH,Zhang B,Kernstine KH,Zhong L

更新日期：2011-03-14 00:00:00

abstract：AIM:To assess the efficacy and safety of TECA type hybrid artificial liver support system (TECA-HALSS) in providing liver function of detoxification, metabolism and physiology by treating the patients with acute liver failure (ALF). METHODS:The porcine liver cells (1-2) x 10(10) were separated from the Chinese small s...

journal_title：World journal of gastroenterology

authors： Xue YL,Zhao SF,Luo Y,Li XJ,Duan ZP,Chen XP,Li WG,Huang XQ,Li YL,Cui X,Zhong DG,Zhang ZY,Huang ZQ

更新日期：2001-12-01 00:00:00

abstract：AIM:To evaluate the possible influences of HCV infection and relative antiviral treatment on seminal parameters and reproductive hormonal serum levels. METHODS:Ten male patients with HCV-related chronic hepatitis and 16 healthy male volunteers were studied. In all subjects seminal parameters (nemaspermic concentration...

journal_title：World journal of gastroenterology

authors： Durazzo M,Premoli A,Di Bisceglie C,Bertagna A,Faga E,Biroli G,Manieri C,Bo S,Pagano G

更新日期：2006-05-21 00:00:00

abstract：AIM:To determine the association of circulating miR-125a/b expression with the risk and disease severity of Crohn's disease (CD), and with inflammatory cytokines. METHODS:Plasma samples were collected from patients with active CD (A-CD), or CD in remission (R-CD) and from healthy controls (HCs). The levels of the infl...

journal_title：World journal of gastroenterology

authors： Sun CM,Wu J,Zhang H,Shi G,Chen ZT

更新日期：2017-11-28 00:00:00

abstract：:Sorafenib is the current standard treatment for advanced hepatocellular carcinoma (HCC), but its efficacy is modest with low response rates and short response duration. Predictive biomarkers for sorafenib efficacy are necessary. However, efforts to determine biomarkers for sorafenib have led only to potential candidat...

journal_title：World journal of gastroenterology

authors： Shao YY,Hsu CH,Cheng AL

更新日期：2015-09-28 00:00:00

abstract：AIM:To investigate the efficacy and safety of gemcitabine (Gem)-based combination chemotherapies for the treatment of advanced biliary tract cancer. METHODS:Clinical trials were identified by searching scientific literature databases (PubMed, EMBASE and the Cochrane Library) for studies published between 1975 and 2013...

journal_title：World journal of gastroenterology

authors： Liu H,Zhang QD,Li ZH,Zhang QQ,Lu LG

更新日期：2014-12-21 00:00:00

abstract：AIM:To assess the efficiency and safety of radiofrequency-assisted hepatectomy in patients with hepatocellular carcinoma (HCC) and cirrhosis. METHODS:From January 2010 to December 2013, 179 patients with HCC and cirrhosis were recruited for this retrospective study. Of these, 100 patients who received radiofrequency-a...

journal_title：World journal of gastroenterology

authors： Zhang F,Yan J,Feng XB,Xia F,Li XW,Ma KS,Bie P

更新日期：2015-09-21 00:00:00

abstract：AIM:To evaluate the efficacy and the safety of combined 5-Fluorouracil, irinotecan, bevacizumab and sirolimus in refractory advanced colorectal carcinoma. METHODS:We initiated a regimen with at day 1 an injection (iv) of bevacizumab at 5 mg/kg, followed by 180 mg/m(2) irinotecan, followed by Leucovorin 400 mg/m(2), fo...

journal_title：World journal of gastroenterology

authors： Ghiringhelli F,Guiu B,Chauffert B,Ladoire S

更新日期：2009-09-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the 10 most common cancers worldwide. There is no ideal treatment for HCC yet and many researchers are trying to improve the effects of treatment by changing therapeutic strategies. As the majority of human cancers seem to exhibit either abnormal p53 gene or disrupted p53 gene ...

journal_title：World journal of gastroenterology

authors： Guan YS,La Z,Yang L,He Q,Li P

更新日期：2007-02-21 00:00:00

abstract：:Hepatitis C virus (HCV) infection disrupts the normal metabolism processes, but is also influenced by several of the host's metabolic factors. An obvious and significantly detrimental pathophysiological feature of HCV infection is insulin resistance in hepatic and peripheral tissues. Substantial research efforts have ...

journal_title：World journal of gastroenterology

authors： Kawaguchi Y,Mizuta T

更新日期：2014-03-21 00:00:00

abstract：BACKGROUND:Pit pattern classification using magnifying chromoendoscopy is the established method for diagnosing colorectal lesions. The Japan Narrow-band-imaging (NBI) Expert Team (JNET) classification is a novel NBI magnifying endoscopic classification that focuses on the vessel, and surface patterns. AIM:To determin...

journal_title：World journal of gastroenterology

authors： Zhang Y,Chen HY,Zhou XL,Pan WS,Zhou XX,Pan HH

更新日期：2020-10-28 00:00:00

abstract：:A 21-year-old woman with complaints of hematochezia was diagnosed as having Cowden's disease (CD), an autosomal dominant condition characterized by multiple hamartomas, since facial papules and gingival papillomas were identified. On endoscopy, multiple hyperplastic polyps were seen in the rectum and left-side colon. ...

journal_title：World journal of gastroenterology

authors： Isomoto H,Furusu H,Ohnita K,Takehara Y,Wen CY,Kohno S

更新日期：2005-03-14 00:00:00