Novel method for extracting exosomes of hepatocellular carcinoma cells.

abstract：:Liver cancers are the second most frequent cause of global cancer-related mortality of which 90% are attributable to hepatocellular carcinoma (HCC). Despite the advent of screening programmes for patients with known risk factors, a substantial number of patients are ineligible for curative surgery at presentation with...

journal_title：World journal of gastroenterology

authors： Inchingolo R,Posa A,Mariappan M,Spiliopoulos S

更新日期：2019-08-28 00:00:00

abstract：AIM:To evaluate the prophylactic efficacy of hepatitis B immunoglobulin (HBIG) in combination with different nucleos(t)ide analogues. METHODS:A total of 5333 hepatitis B surface antigen-positive patients from the China Liver Transplant Registry database were enrolled between January 2000 and December 2009. Low-dose in...

journal_title：World journal of gastroenterology

authors： Shen S,Jiang L,Xiao GQ,Yan LN,Yang JY,Wen TF,Li B,Wang WT,Xu MQ,Wei YG

更新日期：2015-01-14 00:00:00

abstract：:Gastric intramural hematoma is a rare injury of the stomach, and is most often seen in patients with underlying disease. Such injury following endoscopic therapy is even rarer, and there are no universally accepted guidelines for its treatment. In this case report, we describe a gastric intramural hematoma which occur...

journal_title：World journal of gastroenterology

authors： Sun P,Tan SY,Liao GH

更新日期：2012-12-21 00:00:00

abstract：:Gastrointestinal duplication is an uncommon congenital abnormality in two-thirds of cases manifesting before the age of 2 years. Ileal duplication is common while colonic duplication, either cystic or tubular, is a rather unusual clinical entity that remains asymptomatic and undiagnosed in most cases. Mostly occurring...

journal_title：World journal of gastroenterology

authors： Fotiadis C,Genetzakis M,Papandreou I,Misiakos EP,Agapitos E,Zografos GC

更新日期：2005-08-28 00:00:00

abstract：AIM:To investigate if non-peptidic small molecular inhibitors of the p53-HDM2 interaction could restore p53 function and kill tumor cells. METHODS:A series of non-peptidic small HDM2 inhibitors were designed by computer-aided model and synthesized by chemical method. Syl-155 was one of these inhibitors. Cytotoxic effe...

journal_title：World journal of gastroenterology

authors： Li WD,Wang MJ,Ding F,Yin DL,Liu ZH

更新日期：2005-05-21 00:00:00

abstract：:To review the implication of CXCR4 for gastrointestinal cancer, a "Pubmed" analysis was performed in order to evaluate the relevance of CXCR4 and its ligands for gastrointestinal cancers. Search terms applied were "cancer, malignoma, esophageal, gastric, colon, colorectal, hepatic, pancreatic, CXCR4, SDF-1alpha, and S...

journal_title：World journal of gastroenterology

authors： Schimanski CC,Galle PR,Moehler M

更新日期：2008-08-14 00:00:00

abstract：AIM:To identify the clinicopathological predictors of lymph node (LN) metastasis and evaluate the outcomes of endoscopic submucosal dissection (ESD) in papillary adenocarcinoma-type early gastric cancers (EGCs). METHODS:From January 2005 to May 2013, 49 patients who underwent surgical operation and 24 patients who und...

journal_title：World journal of gastroenterology

authors： Lee HJ,Kim GH,Park DY,Lee BE,Jeon HK,Jhi JH,Song GA

更新日期：2015-04-07 00:00:00

abstract：AIM:To analyse the role of genetic susceptibility and environmental factors in the process of esophageal cancer (EC) formation in Xi'an, China. METHODS:A hospital based case-control study, combined with molecular epidemiological method, was carried out. A total of 127 EC cases and 101 controls were interviewed with qu...

journal_title：World journal of gastroenterology

authors： Wang AH,Sun CS,Li LS,Huang JY,Chen QS,Xu DZ

更新日期：2004-04-01 00:00:00

abstract：AIM:To clarify the association of glypican-3 (GPC3) expression with Wnt and other growth signaling molecules in hepatocellular carcinoma (HCC). METHODS:Expression of GPC3, Wnt, matrix metalloproteinases (MMPs), sulfatase (SULF)1, SULF2, and other growth signaling molecules was analyzed in HCC cell lines and tissue sam...

journal_title：World journal of gastroenterology

authors： Akutsu N,Yamamoto H,Sasaki S,Taniguchi H,Arimura Y,Imai K,Shinomura Y

更新日期：2010-07-28 00:00:00

abstract：AIM:To assess the etiology of chronic liver diseases (CLD) from 1998 to 2014 at the outpatient clinic of Gastroenterology of the main hospital in Northwest of Italy among those dedicated to hepatology. METHODS:A random sample of charts of patients referred to for increased liver enzymes between January 1998 and Decemb...

journal_title：World journal of gastroenterology

authors： Saracco GM,Evangelista A,Fagoonee S,Ciccone G,Bugianesi E,Caviglia GP,Abate ML,Rizzetto M,Pellicano R,Smedile A

更新日期：2016-09-28 00:00:00

abstract：AIM:To investigate the anti-diabetogenic mechanism of Nardostachys jatamansi extract (NJE). METHODS:Mice were injected with streptozotocin via a tail vein to induce diabetes. Rat insulinoma RINm5F cells and isolated rat islets were treated with interleukin-1beta and interferon-gamma to induce cytotoxicity. RESULTS:Tr...

journal_title：World journal of gastroenterology

authors： Song MY,Bae UJ,Lee BH,Kwon KB,Seo EA,Park SJ,Kim MS,Song HJ,Kwon KS,Park JW,Ryu DG,Park BH

更新日期：2010-07-14 00:00:00

abstract：AIM:To investigate the dynamic features of insulin-like growth factor-I receptor (IGF-IR) expression in rat hepatocarcinogenesis, and the relationship between IGF-IR and hepatocytes malignant transformation at mRNA or protein level. METHODS:Hepatoma models were made by inducing with 2-fluorenylacetamide (2-FAA) on mal...

journal_title：World journal of gastroenterology

authors： Yan XD,Yao M,Wang L,Zhang HJ,Yan MJ,Gu X,Shi Y,Chen J,Dong ZZ,Yao DF

更新日期：2013-09-28 00:00:00

abstract：AIM:To investigate the efficacy and potential mechanism of Xiaotan Tongfu granules (XTTF) in stress ulcers. METHODS:One hundred sixty rats were randomly divided into 4 groups (n = 10) as follows: the model group (MP group), the control group (CP group), the ranitidine group (RP group) and the XTTF granule group (XP gr...

journal_title：World journal of gastroenterology

authors： Yan B,Shi J,Xiu LJ,Liu X,Zhou YQ,Feng SH,Lv C,Yuan XX,Zhang YC,Li YJ,Wei PK,Qin ZF

更新日期：2013-09-07 00:00:00

abstract：:The continued need to develop less invasive alternatives to surgical and radiologic interventions has driven the development of endoscopic ultrasound (EUS)-guided treatments. These include EUS-guided drainage of pancreatic fluid collections, EUS-guided necrosectomy, EUS-guided cholangiography and biliary drainage, EUS...

journal_title：World journal of gastroenterology

authors： Fabbri C,Luigiano C,Lisotti A,Cennamo V,Virgilio C,Caletti G,Fusaroli P

更新日期：2014-07-14 00:00:00

abstract：AIM:To determine the changes of CD8+ T subsets especially CD8+CD28- T regulatory cells in rat model of experimental colitis induced by 2,4-dinitrofluorobenzene (DNFB). METHODS:The rat model of experimental colitis was induced by enema with DNFB. Ten days later, colonic intraepithelial and splenic lymphocytes were isol...

journal_title：World journal of gastroenterology

authors： Xiao WB,Liu YL

更新日期：2003-11-01 00:00:00

abstract：AIM:To investigate the roles of the adipocytokines, ghrelin and leptin in gastric cancer cachexia. METHODS:Resistin, ghrelin, leptin, adiponectin, insulin and insulin-like growth factor (IGF-I), were measured in 30 healthy subjects, and 60 gastric cancer patients of which 30 suffered from cancer-induced cachexia and 3...

journal_title：World journal of gastroenterology

authors： Kerem M,Ferahkose Z,Yilmaz UT,Pasaoglu H,Ofluoglu E,Bedirli A,Salman B,Sahin TT,Akin M

更新日期：2008-06-21 00:00:00

abstract：AIM:To investigate the effect of diazoxide administration on liver ischemia/reperfusion injury. METHODS:Wistar male rats underwent partial liver ischemia performed by clamping the pedicle from the medium and left anterior lateral segments for 1 h under mechanical ventilation. They were divided into 3 groups: Control G...

journal_title：World journal of gastroenterology

authors： Nogueira MA,Coelho AM,Sampietre SN,Patzina RA,Pinheiro da Silva F,D'Albuquerque LA,Machado MC

更新日期：2014-11-07 00:00:00

abstract：AIM:Recent reports have shown the capacity of mesenchymal stem cells (MSCs) to differentiate into hepatocytes in vitro and in vivo. MSCs administration could repair injured liver, lung, or heart through reducing inflammation, collagen deposition, and remodeling. These results provide a clue to treatment of liver fibros...

journal_title：World journal of gastroenterology

authors： Zhao DC,Lei JX,Chen R,Yu WH,Zhang XM,Li SN,Xiang P

更新日期：2005-06-14 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most lethal cancers, and its rate of incidence is rising annually. Despite the progress in diagnosis and treatment, the overall prognoses of HCC patients remain dismal due to the difficulties in early diagnosis and the high level of tumor invasion, metastasis and recurrence...

journal_title：World journal of gastroenterology

authors： Shang RZ,Qu SB,Wang DS

更新日期：2016-12-07 00:00:00

abstract：AIM:To assess the clinicopathologic characteristics, risk factors, and prognosis for synchronous multiple early gastric cancer (SMGC). METHODS:A total of 146 patients with SMGC and 1194 patients with single gastric cancer who had undergone gastrectomy between 1989 and 2008 were retrospectively analyzed to determine th...

journal_title：World journal of gastroenterology

authors： Isobe T,Hashimoto K,Kizaki J,Murakami N,Aoyagi K,Koufuji K,Akagi Y,Shirouzu K

更新日期：2013-11-07 00:00:00

abstract：AIM:To investigate the relationship between the polymorphism of class II transactivator (CIITA) gene promoters and chronic hepatitis B (CHB). METHODS:Genomic DNA was prepared from peripheral blood leukocytes. Promoters I, III and IV of gene were analyzed respectively with polymerase chain reaction single strand confor...

journal_title：World journal of gastroenterology

authors： Zhao YR,Gong L,He YL,Liu F,Lu C

更新日期：2005-02-14 00:00:00

abstract：BACKGROUND:B-mode-ultrasound-guided percutaneous cholecystostomy (PC) may be performed by a transhepatic or transperitoneal approach, called percutaneous transhepatic gallbladder drainage (PHGD) and percutaneous transperitoneal gallbladder drainage (PPGD), respectively. We compared the impact of PC related to the route...

journal_title：World journal of gastroenterology

authors： Liu P,Liu C,Wu YT,Zhu JY,Zhao WC,Li JB,Zhang H,Yang YX

更新日期：2020-09-28 00:00:00

abstract：AIM:To elucidate high mobility group-box 3 (HMGB3) protein expression in gastric adenocarcinoma, its potential prognostic relevance, and possible mechanism of action. METHODS:Ninety-two patients with gastric adenocarcinomas surgically removed entered the study. HMGB3 expression was determined by immunohistochemistry t...

journal_title：World journal of gastroenterology

authors： Tang HR,Luo XQ,Xu G,Wang Y,Feng ZJ,Xu H,Shi YW,Zhang Q,Wu LG,Xue CQ,Wang CW,Wu CY

更新日期：2012-12-28 00:00:00

abstract：AIM:To evaluate the role of preoperative angiography in the diagnosis and treatment of colorectal cancer. METHODS:The authors performed selective arterial cannulation by Seldinger's method in 47 patients to locate the primary cancer and to diagnose metastasis to the liver. Each patient was then given intra-arterial re...

journal_title：World journal of gastroenterology

authors： Gu J,Ma ZL,Li Y,Li M,Xu GW

更新日期：2003-02-01 00:00:00

abstract：AIM:Positioning of interventional devices in liver lesions is a challenging task if only CT is available. We investigated the potential benefit of combined PET/CT images for localization of interventional devices in interventional liver studies. METHODS:Thirty lesions each of hyperdense, isodense and hypodense attenua...

journal_title：World journal of gastroenterology

authors： Veit P,Kuehle C,Beyer T,Kuehl H,Bockisch A,Antoch G

更新日期：2006-04-21 00:00:00

abstract：AIM:To compare two tests for exocrine pancreatic function (EPF) for use in M-ANNHEIM staging for pancreatitis. METHODS:One hundred and ninety four consecutive patients with acute pancreatitis (AP; n = 13), recurrent acute pancreatitis (RAP; n = 65) and chronic pancreatitis (CP; n = 116) were enrolled. EPF was assessed...

journal_title：World journal of gastroenterology

authors： Kamath MG,Pai CG,Kamath A,Kurien A

更新日期：2017-03-28 00:00:00

abstract：AIM:To retrospectively evaluate the vaccination-induced anti-HBs seroconversion rates in treatment-naive and treatment-experienced chronic hepatitis C (CHC) patients. Also to prospectively evaluate the seroconversion rates in CHC patients during pegylated interferon (PEG) plus ribavirin (RIB) treatment. METHODS:Sevent...

journal_title：World journal of gastroenterology

authors： Elefsiniotis IS,Vezali E,Kamposioras K,Pantazis KD,Tontorova R,Ketikoglou I,Moulakakis A,Saroglou G

更新日期：2006-07-21 00:00:00

abstract：:Celiac disease (CD) is manifested by a variety of clinical signs and symptoms that may begin either in childhood or adult life. Neurological symptoms without signs of malabsorption have been observed for a long time in CD. In this report, an 8-year-old girl with CD presented with rarely seen dilated cardiomyopathy and...

journal_title：World journal of gastroenterology

authors： Doğan M,Peker E,Cagan E,Akbayram S,Acikgoz M,Caksen H,Uner A,Cesur Y

更新日期：2010-05-14 00:00:00

abstract：:Autoimmune pancreatitis has emerged over the last 40 years from a proposed concept to a well established and recognized entity. As an efficient mimicker of pancreatic carcinoma, its early and appropriate recognition are crucial. With mounting understanding of its pathogenesis and natural history, significant advances ...

journal_title：World journal of gastroenterology

authors： Zandieh I,Byrne MF

更新日期：2007-12-21 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is a disease in which excessive fat accumulates in the liver of a patient without a history of alcohol abuse. This disease includes simple steatosis and nonalcoholic steatohepatitis (NASH). NAFLD/NASH is recognized as a hepatic manifestation of metabolic syndrome. In recent yea...

journal_title：World journal of gastroenterology

authors： Takahashi Y,Fukusato T

更新日期：2010-11-14 00:00:00