Relationship between polymorphism of class II transactivator gene promoters and chronic hepatitis B.

Abstract:

AIM:To investigate the relationship between the polymorphism of class II transactivator (CIITA) gene promoters and chronic hepatitis B (CHB). METHODS:Genomic DNA was prepared from peripheral blood leukocytes. Promoters I, III and IV of gene were analyzed respectively with polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) in 65 patients with CHB, 26 patients with acute hepatitis B (AHB) and 85 normal controls. RESULTS:No abnormal migration was found in PCR-SSCP analysis of the three promoters in the three groups. Also, no sequential difference was observed at the three promoters among the CHB patients, AHB patients and normal controls. CONCLUSION:No polymorphism in promoters I, III and IV of CIITA gene exists in CHB patients, ABH patients and normal controls, suggesting that the promoter of CIITA gene might be a conserved domain.

journal_name

World J Gastroenterol

authors

Zhao YR,Gong L,He YL,Liu F,Lu C

doi

10.3748/wjg.v11.i6.854

keywords:

subject

Has Abstract

pub_date

2005-02-14 00:00:00

pages

854-7

issue

6

eissn

1007-9327

issn

2219-2840

journal_volume

11

pub_type

杂志文章
  • Differential gene expression during capillary morphogenesis in a microcarrier-based three-dimensional in vitro model of angiogenesis with focus on chemokines and chemokine receptors.

    abstract:AIM:To globally compare the gene expression profiles during the capillary morphogenesis of human microvascular endothelial cells (HMVECs) in an in vitro angiogenesis system with affymetrix oligonucleotide array. METHODS:A microcarrier-based in vitro angiogenesis system was developed, in which ECs migrated into the mat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i15.2283

    authors: Sun XT,Zhang MY,Shu C,Li Q,Yan XG,Cheng N,Qiu YD,Ding YT

    更新日期:2005-04-21 00:00:00

  • Impact of B-mode-ultrasound-guided transhepatic and transperitoneal cholecystostomy tube placement on laparoscopic cholecystectomy.

    abstract:BACKGROUND:B-mode-ultrasound-guided percutaneous cholecystostomy (PC) may be performed by a transhepatic or transperitoneal approach, called percutaneous transhepatic gallbladder drainage (PHGD) and percutaneous transperitoneal gallbladder drainage (PPGD), respectively. We compared the impact of PC related to the route...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i36.5498

    authors: Liu P,Liu C,Wu YT,Zhu JY,Zhao WC,Li JB,Zhang H,Yang YX

    更新日期:2020-09-28 00:00:00

  • Mycobacterium avium subspecies paratuberculosis causes Crohn's disease in some inflammatory bowel disease patients.

    abstract::Crohn's disease (CD) is a chronic inflammatory condition that plagues millions all over the world. This debilitating bowel disease can start in early childhood and continue into late adulthood. Signs and symptoms are usually many and multiple tests are often required for the diagnosis and confirmation of this disease....

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i23.7403

    authors: Naser SA,Sagramsingh SR,Naser AS,Thanigachalam S

    更新日期:2014-06-21 00:00:00

  • Effects of glutamine on intestinal permeability and bacterial translocation in TPN-rats with endotoxemia.

    abstract:AIM:To evaluate the protective effect and mechanism of glutamine on the intestinal barrier function in total parenteral nutrition (TPN) rats with trauma or endotoxemia. METHODS:To perform prospective, randomized and controlled animal experimentation of rats with surgical trauma, TPN and endotoxemia, thirty-four male, ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i6.1327

    authors: Ding LA,Li JS

    更新日期:2003-06-01 00:00:00

  • Factors related to lymph node metastasis and surgical strategy used to treat early gastric carcinoma.

    abstract:AIM:The prognosis of early gastric carcinoma (EGC) is generally excellent after surgery. The presence or absence of lymph node metastasis in EGC is an important prognostic factor. The survival and recurrence rates of node-negative EGC are much better than those of node-positive EGC. This study examined the factors rela...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i5.737

    authors: Kim DY,Joo JK,Ryu SY,Kim YJ,Kim SK

    更新日期:2004-03-01 00:00:00

  • New totally intracorporeal reconstructive approach after robotic total gastrectomy: Technical details and short-term outcomes.

    abstract:AIM:To show outcomes of our series of patients that underwent a total gastrectomy with a robotic approach and highlight the technical details of a proposed solution for the reconstruction phase. METHODS:Data of gastrectomies performed from May 2014 to October 2016, were extracted and analyzed. Basic characteristics of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i23.4293

    authors: Parisi A,Ricci F,Gemini A,Trastulli S,Cirocchi R,Palazzini G,D'Andrea V,Desiderio J

    更新日期:2017-06-21 00:00:00

  • Update on the management of pancreatic cancer: surgery is not enough.

    abstract::Pancreatic ductal adenocarcinoma (PDAC) represents the fourth cause of death in cancer and has a 5-year survival of < 5%. Only about 15% of the patients present with a resectable PDAC with potential to undergo "curative" surgery. After surgery, local and systemic recurrence, is though very common. The median survival ...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v21.i11.3157

    authors: Ansari D,Gustafsson A,Andersson R

    更新日期:2015-03-21 00:00:00

  • NAT2 6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis.

    abstract:AIM:To investigate an association between N-acetyltransferase 2 (NAT2)-haplotypes/diplotypes and adverse effects in Japanese pulmonary tuberculosis patients. METHODS:We studied 100 patients with pulmonary TB treated with anti-TB drugs including INH. The frequencies and distributions of single nucleotide polymorphisms,...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.45.6003

    authors: Higuchi N,Tahara N,Yanagihara K,Fukushima K,Suyama N,Inoue Y,Miyazaki Y,Kobayashi T,Yoshiura K,Niikawa N,Wen CY,Isomoto H,Shikuwa S,Omagari K,Mizuta Y,Kohno S,Tsukamoto K

    更新日期:2007-12-07 00:00:00

  • Expression of ORF2 partial gene of hepatitis E virus in tomatoes and immunoactivity of expression products.

    abstract:AIM:To transfer hepatitis E virus (HEV) ORF2 partial gene to tomato plants, to investigate its expression in transformants and the immunoactivity of expression products, and to explore the feasibility of developing a new type of plant-derived HEV oral vaccine. METHODS:Plant binary expression vector p1301E2, carrying a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i10.2211

    authors: Ma Y,Lin SQ,Gao Y,Li M,Luo WX,Zhang J,Xia NS

    更新日期:2003-10-01 00:00:00

  • How much helpful is the capsule endoscopy for the diagnosis of small bowel lesions?

    abstract:AIM:To assess the practically usefulness and diagnostic yield of this new method in a group of patients with suspected small bowel lesions. METHODS:Capsule endoscopic (CE) examination by using M2A capsule endoscope TM (Given Imaging, Yoqneam, Israel) was performed in thirty nine patients (26 males, 13 females) with su...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v12.i24.3906

    authors: Ersoy O,Sivri B,Arslan S,Batman F,Bayraktar Y

    更新日期:2006-06-28 00:00:00

  • Barrett's metaplasia: clinical implications.

    abstract::The incidence of Barrett's metaplasia (BM) as well as Barrett's adenocarcinoma (BA) has been increasing in western populations. The prognosis of BA is worse because individuals present at a late stage. Attempts have been made to intervene at early stage using surveillance programmes, although proof of efficacy of endo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v7.i4.563

    authors: Ishaq S,Jankowski JA

    更新日期:2001-08-01 00:00:00

  • Role of MGST1 in reactive intermediate-induced injury.

    abstract::Microsomal glutathione transferase (MGST1, EC 2.5.1.18) is a membrane bound glutathione transferase extensively studied for its ability to detoxify reactive intermediates, including metabolic electrophile intermediates and lipophilic hydroperoxides through its glutathione dependent transferase and peroxidase activitie...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v17.i20.2552

    authors: Schaffert CS

    更新日期:2011-05-28 00:00:00

  • Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells.

    abstract:AIM:To determine the cytological and molecular effects of peroxisome proliferation-activated receptor (PPAR)-gamma and PPAR-gamma agonists on stomach cancer cells. METHODS:To determine the proliferation-suppressive effects of troglitazone and ciglitazone, SNU-216 and SNU-668 stomach cancer cells were plated in media c...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.310

    authors: Cheon CW,Kim DH,Kim DH,Cho YH,Kim JH

    更新日期:2009-01-21 00:00:00

  • Large mucinous biliary cystadenoma with "ovarian-like" stroma: a case report.

    abstract::Hepatobiliary cystadenomas are rare tumors that are difficult to diagnose preoperatively. They can reach large sizes that make them real intraoperative "surprises". A 63-year-old woman, presented with a symptomatic huge abdominal cystic mass, underwent complete resection of the mass with safety margins. Histopathologi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i23.3779

    authors: Beuran M,Venter MD,Dumitru L

    更新日期:2006-06-21 00:00:00

  • Seven synchronous early gastric cancer with 28 lymph nodes metastasis.

    abstract::An 85 year male patient complaining epigastric discomfort was admitted. From the esophagogastroduodenoscopy, three early gastric cancer (EGCa) lesions had been identified and these were diagnosed as adenocarcinoma with poorly differentiated cell type. The patient underwent operation. From the post-operative mapping, h...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i44.8141

    authors: Seong H,Kim JI,Lee HJ,Kim HJ,Cho HJ,Kim HK,Cheung DY,Kim DJ,Kim W,Kim TJ

    更新日期:2013-11-28 00:00:00

  • Multidrug-resistant bacterial infections after liver transplantation: an ever-growing challenge.

    abstract::Bacterial infections are a leading cause of morbidity and mortality among solid organ transplant recipients. Over the last two decades, various multidrug-resistant (MDR) pathogens have emerged as relevant causes of infection in this population. Although this fact reflects the spread of MDR pathogens in health care fac...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i20.6201

    authors: Santoro-Lopes G,de Gouvêa EF

    更新日期:2014-05-28 00:00:00

  • Epidemiology, demographic characteristics and prognostic predictors of ulcerative colitis.

    abstract::Ulcerative colitis (UC) is a chronic disease characterized by diffuse inflammation of the mucosa of the colon and rectum. The hallmark clinical symptom of UC is bloody diarrhea. The clinical course is marked by exacerbations and remissions, which may occur spontaneously or in response to treatment changes or intercurr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i28.9458

    authors: da Silva BC,Lyra AC,Rocha R,Santana GO

    更新日期:2014-07-28 00:00:00

  • Examining pathogenic concepts of autoimmune hepatitis for cues to future investigations and interventions.

    abstract::Multiple pathogenic mechanisms have been implicated in autoimmune hepatitis, but they have not fully explained susceptibility, triggering events, and maintenance or escalation of the disease. Furthermore, they have not identified a critical defect that can be targeted. The goals of this review are to examine the diver...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v25.i45.6579

    authors: Czaja AJ

    更新日期:2019-12-07 00:00:00

  • Effects of CPG ODN on biological behavior of PANC-1 and expression of TLR9 in pancreatic cancer.

    abstract:AIM:To determine the expression of toll-like receptor 9 (TLR9) in pancreatic tumor and the effects of cytosine phosphate-guanosine oligodeoxynucleotides 2216 (CPG ODN2216) on biological behavior of pancreatic carcinoma cell line PANC-1 and explore their clinical significance. METHODS:The immunohistochemistry and Weste...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i8.996

    authors: Wu HQ,Wang B,Zhu SK,Tian Y,Zhang JH,Wu HS

    更新日期:2011-02-28 00:00:00

  • Hepatoma with cardiac metastasis: an advanced cancer requiring advanced treatment.

    abstract:AIM:To investigate the clinical and pathologic findings, and to discuss the pathophysiology of hepatocellular carcinoma with cardiac metastasis. METHODS:Eight hepatoma patients with cardiac metastasis, who were treated by surgical excision from 1993 to 2006, were retrospectively studied. Detailed clinical parameters w...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i25.3513

    authors: Lin YS,Jung SM,Tsai FC,Yeh CN,Shiu TF,Wu HH,Lin PJ,Chu PH

    更新日期:2007-07-07 00:00:00

  • Endoscopic diagnosis of Barrett's esophagus.

    abstract::The Prague C and M Criteria have been developed for the objective endoscopic diagnosis of Barrett's esophagus (BE). BE arises between the squamocolumnar junction and the gastroesophageal junction at the proximal margin of the gastric folds. In this study, we reported that 43.0% of the subjects examined were diagnosed ...

    journal_title:World journal of gastroenterology

    pub_type: 信件

    doi:10.3748/wjg.v18.i26.3477

    authors: Akiyama T,Sekino Y,Iida H,Koyama S,Gotoh E,Maeda S,Nakajima A,Inamori M

    更新日期:2012-07-14 00:00:00

  • Evidence of human papilloma virus infection and its epidemiology in esophageal squamous cell carcinoma.

    abstract:AIM:To look for the evidence of human papilloma virus (HPV) infection in esophageal squamous cell carcinomas (ESCC) and to investigate the potential role and epidemiology of HPV infection in the pathogenesis of esophageal carcinomas in Henan emigrants. METHODS:Papilloma virus(PV) and HPV were determined by Ultrasensiv...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i9.1352

    authors: Yao PF,Li GC,Li J,Xia HS,Yang XL,Huang HY,Fu YG,Wang RQ,Wang XY,Sha JW

    更新日期:2006-03-07 00:00:00

  • Foreign body impaction in the sigmoid colon: a twenty euro bet.

    abstract::Foreign body ingestion is a common clinical problem in early childhood. However, it may occur even in adults, unknowingly. Most ingested foreign bodies entering the stomach pass through the gastrointestinal tract uneventfully. Here we report on a 13-year-old boy who presented with chronic abdominal pain, weight loss a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i24.3892

    authors: Müller KE,Arató A,Lakatos PL,Papp M,Veres G

    更新日期:2013-06-28 00:00:00

  • Strangulated diaphragmatic hernia presenting clinically as pericarditis.

    abstract::A case of strangulation of the transverse colon in a traumatic left diaphragmatic hernia manifesting as pericarditis is reported. This is unusual because pericardial signs in traumatic diaphragmatic hernia have been previously described in association with direct pericardial injury. This is the only such case where el...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i9.1449

    authors: Makhija R,Akoh JA

    更新日期:2007-03-07 00:00:00

  • Prevalence of celiac disease in adult patients with refractory functional dyspepsia: value of routine duodenal biopsy.

    abstract:AIM:To investigate the prevalence of celiac disease (CD) in adult patients referred to an open access gastroenterology clinic in the south of Italy and submitted to esophago-gastro-duodenoscopy (EGD) for evaluation of refractory functional dyspepsia. METHODS:Seven hundred and twenty six consecutive dyspeptic patients ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.6948

    authors: Giangreco E,D'agate C,Barbera C,Puzzo L,Aprile G,Naso P,Bonanno G,Russo FP,Nicoletti A,Incarbone S,Trama G,Russo A

    更新日期:2008-12-07 00:00:00

  • Chinese guidelines on the management of liver cirrhosis (abbreviated version).

    abstract::Based on reviews of the literature and experts' consensus, the Chinese Society of Hepatology developed guidelines for the diagnosis and treatment of liver cirrhosis, in order to improve clinical practice. In addition to what has been covered in previously published guidelines on the management of cirrhosis complicatio...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v26.i45.7088

    authors: Xu XY,Ding HG,Li WG,Xu JH,Han Y,Jia JD,Wei L,Duan ZP,Ling-Hu EQ,Zhuang H

    更新日期:2020-12-07 00:00:00

  • Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon.

    abstract::Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions are well established biological events which have an important role in not just normal tissue and organ development, but in the pathogenesis of diseases. Increasing evidence has established their presence in the human colon during colorectal carcinoge...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v18.i7.601

    authors: Sipos F,Galamb O

    更新日期:2012-02-21 00:00:00

  • E2F transcription factors and digestive system malignancies: how much do we know?

    abstract::E2F family of transcription factors regulates various cellular functions related to cell cycle and apoptosis. Its individual members have traditionally been classified into activators and repressors, based on in vitro studies. However their contribution in human cancer is more complicated and difficult to predict. We ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v19.i21.3189

    authors: Xanthoulis A,Tiniakos DG

    更新日期:2013-06-07 00:00:00

  • Detection of carcinoembryonic antigen mRNA in peritoneal washes from gastric cancer patients and its clinical significance.

    abstract:AIM:To establish a more sensitive method for detection of free cancer cells in peritoneal washes from gastric cancer patients during surgery and to evaluate its clinical significance. METHODS:The carcinoembryonic antigen (CEA) mRNA levels in peritoneal washes from 65 cases of gastric cancer were detected by real-time ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i9.1408

    authors: Zhang YS,Xu J,Luo GH,Wang RC,Zhu J,Zhang XY,Nilsson-Ehle P,Xu N

    更新日期:2006-03-07 00:00:00

  • Metastatic breast cancer to the gastrointestinal tract: a case series and review of the literature.

    abstract::Metastatic breast cancer involving the hepatobiliary tract or ascites secondary to peritoneal carcinomatosis has been well described. Luminal gastrointestinal tract involvement is less common and recognition of the range of possible presentations is important for early and accurate diagnosis and treatment. We report 6...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v12.i38.6219

    authors: Nazareno J,Taves D,Preiksaitis HG

    更新日期:2006-10-14 00:00:00