Hepatoma with cardiac metastasis: an advanced cancer requiring advanced treatment.

Abstract:

AIM:To investigate the clinical and pathologic findings, and to discuss the pathophysiology of hepatocellular carcinoma with cardiac metastasis. METHODS:Eight hepatoma patients with cardiac metastasis, who were treated by surgical excision from 1993 to 2006, were retrospectively studied. Detailed clinical parameters were analyzed. RESULTS:Of those eight patients, two (25%) were women and six (75%) were men, with the mean age of 50 years (range, 40-70 years). The presentations included: asymptomatic (75%), heart failure (25%), and pulmonary embolism (12.5%). All lesions involved the right atrium, and extended to the lung (12.5%), inferior vena cava (25%), and left atrium (12.5%). The level of tumor marker, alpha-fetal protein, was not correlated with the severity of metastasis or disease prognosis. Moreover, the availably estimated doubling time was less than 3 mo. The pathological findings included variable hemorrhage and necrosis. The survival time following surgery also varied from one month to more than 30 mo. CONCLUSION:Hepatoma metastasis to the heart was detected in all eight patients. This study demonstrates that surgery might help the outcome in such cases.

journal_name

World J Gastroenterol

authors

Lin YS,Jung SM,Tsai FC,Yeh CN,Shiu TF,Wu HH,Lin PJ,Chu PH

doi

10.3748/wjg.v13.i25.3513

subject

Has Abstract

pub_date

2007-07-07 00:00:00

pages

3513-6

issue

25

eissn

1007-9327

issn

2219-2840

journal_volume

13

pub_type

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