Therapeutic drug monitoring in patients with inflammatory bowel disease.

abstract：AIM:To evaluate the diagnostic efficiency of endoscopic ultrasound (EUS) as the main imaging modality in patients with moderate suspicion of common bile duct stones (CBDS). METHODS:55 patients with moderate clinical suspicion of CBDS were prospectively included to the study and evaluated with EUS. This study was done ...

journal_title：World journal of gastroenterology

authors： Kohut M,Nowak A,Nowakowska-Dulawa E,Marek T,Kaczor R

更新日期：2003-03-01 00:00:00

abstract：AIM:To investigate the effects and mechanisms of melatonin on immunological liver injury in mice. METHODS:A model of liver injury was induced by tail vein injection of Bacillus Calmette Guerin (BCG) and lipopolysaccharide (LPS) in mice. Kupffer cells and hepatocytes were isolated and cultured according to a modified t...

journal_title：World journal of gastroenterology

authors： Wang H,Wei W,Shen YX,Dong C,Zhang LL,Wang NP,Yue L,Xu SY

更新日期：2004-09-15 00:00:00

abstract：:Neurofibromas of the large bowel are very rare and usually are part of the colonic involvement in neurofibromatosis type 1 (Nf1, von Recklinghausen's disease). Solitary neurofibromas of the colon are extremely rare. We describe a case of an isolated neurofibroma that was found in the large bowel of a patient who suffe...

journal_title：World journal of gastroenterology

authors： Panteris V,Vassilakaki T,Vaitsis N,Elemenoglou I,Mylonakou I,Karamanolis DG

更新日期：2005-09-21 00:00:00

abstract：:The clinical course of chronic liver diseases is significantly dependent on the progression rate and the extent of fibrosis, i.e. the non-structured replacement of necrotic parenchyma by extracellular matrix. Fibrogenesis, i.e. the development of fibrosis can be regarded as an unlimited wound healing process, which is...

journal_title：World journal of gastroenterology

authors： Gressner AM,Gao CF,Gressner OA

更新日期：2009-05-28 00:00:00

abstract：AIM:To investigate if non-peptidic small molecular inhibitors of the p53-HDM2 interaction could restore p53 function and kill tumor cells. METHODS:A series of non-peptidic small HDM2 inhibitors were designed by computer-aided model and synthesized by chemical method. Syl-155 was one of these inhibitors. Cytotoxic effe...

journal_title：World journal of gastroenterology

authors： Li WD,Wang MJ,Ding F,Yin DL,Liu ZH

更新日期：2005-05-21 00:00:00

abstract：AIM:To evaluate the inhibition effect of HCV NS5A on p53 transactivation on p21 promoter and explore its possible mechanism for influencing p53 function. METHODS:p53 function of transactivation on p21 promoter was studied with a luciferase reporter system in which the luciferase gene is driven by p21 promoter, and the...

journal_title：World journal of gastroenterology

authors： Gong GZ,Jiang YF,He Y,Lai LY,Zhu YH,Su XS

更新日期：2004-08-01 00:00:00

abstract：:Most medical specialties including the field of gastroenterology are mainly aimed at treating diseases rather than preventing them. Genomic medicine studies the health/disease process based on the interaction of the human genes with the environment. The gastrointestinal (GI) system is an ideal model to analyze the int...

journal_title：World journal of gastroenterology

authors： Panduro A,Rivera-Iñiguez I,Sepulveda-Villegas M,Roman S

更新日期：2017-05-07 00:00:00

abstract：:Gastric cancer is the second leading cause of cancer mortality worldwide. The diagnosis of gastric cancer has been significantly improved with the broad availability of gastrointestinal endoscopy. Effective technologies for accurate staging and quantitative evaluation are still in demand to merit reasonable treatment ...

journal_title：World journal of gastroenterology

authors： Wu CX,Zhu ZH

更新日期：2014-04-28 00:00:00

abstract：AIM:To conduct a multicentre retrospective review of virological response rates in Asians infected with genotype 1 chronic hepatitis C (CHC) treated with combination interferon and ribavirin and then to compare their responses to that among Caucasians. METHODS:Asian patients infected with genotype 1 CHC treated at 4 A...

journal_title：World journal of gastroenterology

authors： Yan KK,Guirgis M,Dinh T,George J,Dev A,Lee A,Zekry A

更新日期：2008-06-07 00:00:00

abstract：:Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts. In immunocompromised individuals, particularly transplanted patie...

journal_title：World journal of gastroenterology

authors： Umbro I,Tinti F,Muiesan P,Mitterhofer AP

更新日期：2016-01-28 00:00:00

abstract：:Acute pancreatitis constitutes 3% of all admissions with abdominal pain. There are reports of osteal fat necrosis leading to periosteal reactions and osteolytic lesions following severe pancreatitis, particularly in long bones. A 54-year-old man was admitted to our hospital with acute pancreatitis, who later developed...

journal_title：World journal of gastroenterology

authors： Muthukumarasamy G,Shanmugam V,Yule SR,Ravindran R

更新日期：2007-07-21 00:00:00

abstract：AIM:To investigate the effect of APOBEC3G mediated antiviral activity against hepatitis B virus (HBV) in cell cultures and replication competent HBV vector-based mouse model. METHODS:The mammalian hepatoma cells Huh7 and HepG2 were cotransfected with various amounts of CMV-driven expression vector encoding APOBEC3G an...

journal_title：World journal of gastroenterology

authors： Lei YC,Hao YH,Zhang ZM,Tian YJ,Wang BJ,Yang Y,Zhao XP,Lu MJ,Gong FL,Yang DL

更新日期：2006-07-28 00:00:00

abstract：:Pseudo-Meigs' syndrome associated with colorectal cancer is extremely rare. We report here a case of pseudo-Meigs' syndrome secondary to metachronous ovarian metastases from colon cancer. A 65-year-old female with a history of surgery for transverse colon cancer and peritoneal dissemination suffered from metachronous ...

journal_title：World journal of gastroenterology

authors： Kyo K,Maema A,Shirakawa M,Nakamura T,Koda K,Yokoyama H

更新日期：2016-05-14 00:00:00

abstract：:Hepatitis C virus (HCV) infects approximately 170 million individuals worldwide. Prevention of HCV infection complications is based on antiviral therapy with the combination of pegylated interferon alfa and ribavirin. The use of serological and virological tests has become essential in the management of HCV infection ...

journal_title：World journal of gastroenterology

authors： Chevaliez S,Pawlotsky JM

更新日期：2007-05-07 00:00:00

abstract：AIM:To identify a molecular marker for gastric cancer, and to investigate the relationship between the polymorphism of pepsinogen C (PGC) gene and the genetic predisposition to gastric cancer. METHODS:A total of 289 cases were involved in this study. 115 cases came from Shenyang area, a low risk area of gastric cancer...

journal_title：World journal of gastroenterology

authors： Liu HJ,Guo XL,Dong M,Wang L,Yuan Y

更新日期：2003-01-01 00:00:00

abstract：:Two major types of cancer occur in the esophagus: squamous cell carcinoma, which is associated with chronic smoking and alcohol consumption, and adenocarcinoma, which typically arises in gastric reflux-associated Barrett's esophagus. Although there is increasing incidence of esophageal adenocarcinoma in Western counti...

journal_title：World journal of gastroenterology

authors： Sasaki Y,Tamura M,Koyama R,Nakagaki T,Adachi Y,Tokino T

更新日期：2016-02-21 00:00:00

abstract：:The occurrence of adult intussusception from small intestinal lymphoma is quite rare. We present an 82-year-old man with a two-month history of intermittent abdominal pain, nausea and fatigue. Clinical symptoms included moderate abdominal tenderness in the right lower abdomen. Computed tomography scan of the abdomen r...

journal_title：World journal of gastroenterology

authors： Xu XQ,Hong T,Li BL,Liu W

更新日期：2013-12-07 00:00:00

abstract：AIM:To investigate the role of Delta-like ligand 4 (DLL4) on tumour growth in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) in vivo. METHODS:We suppressed DLL4 expression in an HBV expressing HCC cell line, HepG2.2.15 and analysed the growth ability of cells as subcutaneous tumours in nude mice. Th...

journal_title：World journal of gastroenterology

authors： Kunanopparat A,Issara-Amphorn J,Leelahavanichkul A,Sanpavat A,Patumraj S,Tangkijvanich P,Palaga T,Hirankarn N

更新日期：2018-09-14 00:00:00

abstract：AIM:To investigate the effect of pituitary homeobox 1 (PITX1) expression in cases of human gastric cancer on cancer differentiation and progression, and carcinogenesis. METHODS:Using polyclonal PITX1 antibodies, we studied the expression of PITX1 in normal gastric mucosa, atypical hyperplasia, intestinal metaplasia, a...

journal_title：World journal of gastroenterology

authors： Chen YN,Chen H,Xu Y,Zhang X,Luo Y

更新日期：2008-01-14 00:00:00

abstract：:Benign multicystic peritoneal mesothelioma (BMPM) is a rare cystic mesothelial lesion that occurs predominantly in reproductive aged women. A 56-year-old Caucasian male was admitted to our surgical department with a chief complaint of a painful mass in his right lower abdomen for almost 2 years. The physical examinati...

journal_title：World journal of gastroenterology

authors： Wang TB,Dai WG,Liu DW,Shi HP,Dong WG

更新日期：2013-10-21 00:00:00

abstract：AIM:To identify the prevalence of hepatitis B e antigen (HBeAg) and to assess the association of hepatitis B virus (HBV) core promoter mutations and viral load in Indonesian patients. METHODS:Sixty-four patients with chronic hepatitis, 65 with liver cirrhosis and 50 with hepatocellular carcinoma were included in this ...

journal_title：World journal of gastroenterology

authors： Utama A,Siburian MD,Purwantomo S,Intan MD,Kurniasih TS,Gani RA,Achwan WA,Arnelis,Lelosutan SA,Lukito B,Harmono T,Zubir N,Julius,Soemohardjo S,Lesmana LA,Sulaiman A,Tai S

更新日期：2011-02-14 00:00:00

abstract：:Benign duodenal tumors are rare and less common than malignant tumors. Furthermore, vascular lesions of the duodenum, including hemangiomas, are rare causes of gastrointestinal bleeding. This report describes a case with bleeding hemangiomas in the third portion of the duodenum and jejunum and their successful treatme...

journal_title：World journal of gastroenterology

authors： Kanaji S,Nakamura T,Nishi M,Yamamoto M,Kanemitu K,Yamashiita K,Imanishi T,Sumi Y,Suzuki S,Tanaka K,Kakeji Y

更新日期：2014-09-14 00:00:00

abstract：:Although primary gastrointestinal lymphoma is a rare malignancy, it can cause an intussusception in adults and can be a clinically challenging condition to manage. Intussusception could progress to life-threatening complications if left untreated or could delay chemotherapy if inappropriate surgical management is used...

journal_title：World journal of gastroenterology

authors： Yang TW,Lin YY,Tsuei YW,Chen YL,Huang CY,Hsu SD

更新日期：2016-05-21 00:00:00

abstract：:Primary sclerosing cholangitis (PSC) is a chronic, progressive, cholestatic liver disease characterized by inflammation and fibrotic obliteration of the hepatic biliary tree. It is commonly associated with inflammatory bowel disease (IBD). A number of complications can occur which require special consideration, the mo...

journal_title：World journal of gastroenterology

authors： Shorbagi A,Bayraktar Y

更新日期：2008-07-07 00:00:00

abstract：:Endoscopic retrograde cholangiopancreatography (ERCP) is a state of the art diagnostic and therapeutic procedure for various pancreatic and biliary problems. In spite of the well-established safety of the procedure, there is still a risk of complications such as pancreatitis, cholangitis, bleeding and perforation. Air...

journal_title：World journal of gastroenterology

authors： Yilmaz B,Roach EC,Koklu S,Aydin O,Unlu O,Kilic YA

更新日期：2015-04-21 00:00:00

abstract：AIM:To study the relationship between the patterns of postprandial peristalsis and transduodenal bolus transport in healthy subjects. METHODS:Synchronous recording of chyme transport and peristaltic activity was performed during the fasting state and after administration of a test meal using a special catheter device ...

journal_title：World journal of gastroenterology

authors： Nguyen HN,Winograd R,Domingues GR,Lammert F

更新日期：2006-10-07 00:00:00

abstract：AIM:To investigate whether American ginseng (AG, Panax quinquefolium) supplementation was able to improve endurance exercise performance. METHODS:Thirteen physically active male college students were divided into two groups (AG or placebo) and received supplementation for 4 wk, before the exhaustive running exercise. ...

journal_title：World journal of gastroenterology

authors： Hsu CC,Ho MC,Lin LC,Su B,Hsu MC

更新日期：2005-09-14 00:00:00

abstract：:We report a case of a 32-year-old woman with episodic right lower quadrant abdominal pain. With the diagnosis of either acute appendicitis or tubo-ovarian abscess, she was treated with antibiotics, which successfully relieved the pain and the inflammatory findings. She repeated the clinical condition a few times and a...

journal_title：World journal of gastroenterology

authors： Niwa H,Hiramatsu T

更新日期：2008-02-28 00:00:00

abstract：AIM:To investigate the relationship of changes in expression of marker genes in functional categories or molecular networks comprising one functional category or multiple categories in progression of hepatic fibrosis in hepatitis C (HCV) patients. METHODS:Marker genes were initially identified using DNA microarray dat...

journal_title：World journal of gastroenterology

authors： Takahara Y,Takahashi M,Zhang QW,Wagatsuma H,Mori M,Tamori A,Shiomi S,Nishiguchi S

更新日期：2008-04-07 00:00:00

abstract：:Intestinal Ca(2+) absorption is a crucial physiological process for maintaining bone mineralization and Ca(2+) homeostasis. It occurs through the transcellular and paracellular pathways. The first route comprises 3 steps: the entrance of Ca(2+) across the brush border membranes (BBM) of enterocytes through epithelial ...

journal_title：World journal of gastroenterology

authors： Diaz de Barboza G,Guizzardi S,Tolosa de Talamoni N

更新日期：2015-06-21 00:00:00