NAT2 6A, a haplotype of the N-acetyltransferase 2 gene, is an important biomarker for risk of anti-tuberculosis drug-induced hepatotoxicity in Japanese patients with tuberculosis.

abstract：AIM:To investigate the risk indicators, pattern of clinical presentation and treatment strategy of superior mesenteric artery syndrome (SMAS) after scoliosis surgery. METHODS:From July 1997 to October 2003, 640 patients with adolescent scoliosis who had undergone surgical treatment were evaluated prospectively, and am...

journal_title：World journal of gastroenterology

authors： Zhu ZZ,Qiu Y

更新日期：2005-06-07 00:00:00

abstract：:This review focused in the perioperative management of patients with pancreatic cancer in order to improve the outcome of the disease. We consider that the most controversial points in pancreatic cancer management are jaundice management, vascular resection and neo-adjuvant therapy. Preoperative biliary drainage is re...

journal_title：World journal of gastroenterology

authors： Alamo JM,Marín LM,Suarez G,Bernal C,Serrano J,Barrera L,Gómez MA,Muntané J,Padillo FJ

更新日期：2014-10-21 00:00:00

abstract：AIM:To investigate the ultrastructure of abnormal hepatocyte mitochondria, including their cellular and hepatic zonal distribution, in bioptates in pediatric non-alcoholic steatohepatitis (NASH). METHODS:Ultrastructural investigations were conducted on biopsy liver specimens obtained from 10 children (6 boys and 4 gir...

journal_title：World journal of gastroenterology

authors： Lotowska JM,Sobaniec-Lotowska ME,Bockowska SB,Lebensztejn DM

更新日期：2014-04-21 00:00:00

abstract：:Lipoma is relatively common in the colon but is less often in the small intestine. Most lipomas are incidentally detected at endoscopy and are usually small and asymptomatic. However, some of them can present with obstruction and/or intussusceptions. Surgical resection is commonly recommended to remove such significan...

journal_title：World journal of gastroenterology

authors： Morimoto T,Fu KI,Konuma H,Izumi Y,Matsuyama S,Ogura K,Miyazaki A,Watanabe S

更新日期：2010-04-07 00:00:00

abstract：AIM:To evaluate the clinical advantages of single-port laparoscopic hepatectomy (SPLH) compare to multi-port laparoscopic hepatectomy (MPLH). METHODS:We retrospectively reviewed the medical records of 246 patients who underwent laparoscopic liver resection between January 2008 and December 2015 at our hospital. We div...

journal_title：World journal of gastroenterology

authors： Han JH,You YK,Choi HJ,Hong TH,Kim DG

更新日期：2018-01-21 00:00:00

abstract：:Innate lymphoid cells (ILCs) are defined as a distinct arm of innate immunity. According to their profile of secreted cytokines and lineage-specific transcriptional factors, ILCs can be categorized into the following three groups: group 1 ILCs (including natural killer (NK) cells and ILC1s) are dependent on T-bet and ...

journal_title：World journal of gastroenterology

authors： Shen Y,Li J,Wang SQ,Jiang W

更新日期：2018-05-14 00:00:00

abstract：:AIM:To study the clinical significance of the diagnosis and catheterized interventional treatment of digital subtraction angiography (DSA) for pancreatic tumors.METHODS: Ninety-two patients with pancreatic tumor, 69 males and 23 females, aged from 41 to 70 years (mean 57.1 years) were diagnosed with DSA. Sixty-one pat...

journal_title：World journal of gastroenterology

authors： Xu HB,Zhang YJ,Wei WJ,Li WM,Tu XQ

更新日期：1998-02-01 00:00:00

abstract：:Angiosarcoma is a rare primary malignant neoplasm of the liver with a poor prognosis. Here, we report a case of a patient with a ruptured hepatic angiosarcoma which was treated by emergency catheter-directed embolization, followed by left-sided hemihepatectomy. ...

journal_title：World journal of gastroenterology

authors： Leowardi C,Hormann Y,Hinz U,Wente MN,Hallscheidt P,Flechtenmacher C,Buchler MW,Friess H,Schwarzbach MH

更新日期：2006-02-07 00:00:00

abstract：AIM:Granuloma is considered the hallmark of microscopic diagnosis in Crohn's disease (CD), but granulomas can be detected in only 21-60% of CD patients. The aim of this study was to evaluate the frequency of granulomas by multiple endoscopic biopsies in patients with CD and to examine whether group of patients with or ...

journal_title：World journal of gastroenterology

authors： Molnár T,Tiszlavicz L,Gyulai C,Nagy F,Lonovics J

更新日期：2005-05-28 00:00:00

abstract：AIM:To investigate the relationship between Helicobacter pylori (H. pylori) and mucin expression in gastric mucosa. METHODS:English Medical literature searches were conducted for gastric mucin expression in H. pylori infected people vs uninfected people. Searches were performed up to December 31(th) 2014, using MEDLIN...

journal_title：World journal of gastroenterology

authors： Niv Y

更新日期：2015-08-21 00:00:00

abstract：:The motor function of the gastrointestinal tract has primarily been studied using manometry and radiography, though more indirect tests have also been applied. Manometry and radiography do not provide detailed information about the muscle properties as can be assessed from studies of muscle properties in muscle strips...

journal_title：World journal of gastroenterology

authors： Gregersen H,Liao D

更新日期：2006-05-14 00:00:00

abstract：AIM:To determine whether the gastrin stimulated intestinal crypt cell (IEC-6) proliferation by induction of ornithine decarboxylase (ODC). METHODS:IEC-6 cells were grown in DMEM containing 50 mL x L(-1) dialyzed fetal bovine serum for 24h and then were treated with gastrin. The proliferative capability of the cells wa...

journal_title：World journal of gastroenterology

authors： Zhang ZL,Chen WW

更新日期：2002-02-01 00:00:00

abstract：AIM:To evaluate the usefulness of contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) in differentiating between pancreatic adenocarcinomas and other pancreatic disease. METHODS:This retrospective cohort study evaluated 90 patients who were seen between November 2010 and May 2013. All these patients had solid pa...

journal_title：World journal of gastroenterology

authors： Park JS,Kim HK,Bang BW,Kim SG,Jeong S,Lee DH

更新日期：2014-01-14 00:00:00

abstract：:Human intestinal microbiota create a complex polymicrobial ecology. This is characterised by its high population density, wide diversity and complexity of interaction. Any dysbalance of this complex intestinal microbiome, both qualitative and quantitative, might have serious health consequence for a macro-organism, in...

journal_title：World journal of gastroenterology

authors： Bures J,Cyrany J,Kohoutova D,Förstl M,Rejchrt S,Kvetina J,Vorisek V,Kopacova M

更新日期：2010-06-28 00:00:00

abstract：:As among persons with normal anatomy, occasional patients with situs inversus develop malignant tumors. Recently, several laparoscopic operations have been reported in patients with situs inversus. We describe laparoscopic hemicolectomy with radical lymphadenectomy in such a patient. Careful consideration of the mirro...

journal_title：World journal of gastroenterology

authors： Fujiwara Y,Fukunaga Y,Higashino M,Tanimura S,Takemura M,Tanaka Y,Osugi H

更新日期：2007-10-07 00:00:00

abstract：AIM:Various side effects have been reported in patients infected with hepatitis C virus (HCV) who were treated with interferon-alpha (IFN-alpha), including the appearance or exacerbation of underlying autoimmune diseases and the development of a variety of organ and non-organ specific autoantibodies (NOSA). However, ve...

journal_title：World journal of gastroenterology

authors： Gatselis NK,Georgiadou SP,Tassopoulos N,Zachou K,Liaskos C,Hatzakis A,Dalekos GN

更新日期：2005-01-28 00:00:00

abstract：AIM:To investigate the role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning (IPC). METHODS:A rat model of acute hepatic ischemia-reperfusion was established, 24 healthy male Wistar rats were randomly divided into sham-operated group, ische...

journal_title：World journal of gastroenterology

authors： Sun K,Liu ZS,Sun Q

更新日期：2004-07-01 00:00:00

abstract：AIM:To compare the results for endoscopic ultrasound (EUS)-guided drainage of clear fluid pancreatic pseudocysts with the results for abscess drainage. METHODS:All patients referred for endoscopic drainage of a fluid collection were prospectively included. The outcome was recorded. RESULTS:Altogether 26 pseudocysts o...

journal_title：World journal of gastroenterology

authors： Sadik R,Kalaitzakis E,Thune A,Hansen J,Jönson C

更新日期：2011-01-28 00:00:00

abstract：AIM:To detect high risk patients with a progressive disease course of ulcerative colitis (UC) requiring immunosuppressive therapy (IT). METHODS:A retrospective, multicenter analysis of 262 UC patients from eight German tertiary inflammatory bowel disease centres was performed. Patients were divided into two groups dep...

journal_title：World journal of gastroenterology

authors： Stallmach A,Nickel L,Lehmann T,Bokemeyer B,Bürger M,Hüppe D,Kruis W,Nikolaus S,Preiss JC,Sturm A,Teich N,Schmidt C

更新日期：2014-09-21 00:00:00

abstract：AIM:To evaluate the clinical characteristics of nonvariceal upper gastrointestinal hemorrhage (NGIH) in patients with chronic kidney disease (CKD). METHODS:From 2003 to 2010, a total of 72 CKD patients (male n = 52, 72.2%; female n = 20, 27.8%) who had undergone endoscopic treatments for NGIH were retrospectively iden...

journal_title：World journal of gastroenterology

authors： Bang CS,Lee YS,Lee YH,Sung H,Park HJ,Kim HS,Kim JB,Baik GH,Kim YS,Yoon JH,Kim DJ,Suk KT

更新日期：2013-11-21 00:00:00

abstract：AIM:To assess the efficacy and safety of fourth-generation quinolones for Helicobacter pylori (H. pylori) eradication, we conducted this systematic review and meta-analysis of randomized clinical trials. METHODS:Major literature databases (PubMed, EMBASE and the Cochrane Central Register of Controlled Trials) were sea...

journal_title：World journal of gastroenterology

authors： An Y,Wang Y,Wu S,Wang YH,Qian X,Li Z,Fu YJ,Xie Y

更新日期：2018-08-07 00:00:00

abstract：AIM:To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death. METHODS:We used data extracted from the Registry of Upper Gastrointestinal Bleeding and Endoscopy including information of 1869 patients with non-variceal upper gastrointestinal bleeding t...

journal_title：World journal of gastroenterology

authors： Enns RA,Gagnon YM,Barkun AN,Armstrong D,Gregor JC,Fedorak RN,RUGBE Investigators Group.

更新日期：2006-12-28 00:00:00

abstract：AIM:To explore the regulator of G-protein signaling 5 (RGS5) expression in gastric carcinoma and its association with differentiation and microvascular density (MVD). METHODS:Expression of RGS5 and CD34 were examined in 76 cases of gastric carcinoma, including 22 cases with lymph node metastasis and 54 cases without l...

journal_title：World journal of gastroenterology

authors： Wang JH,Huang WS,Hu CR,Guan XX,Zhou HB,Chen LB

更新日期：2010-11-28 00:00:00

abstract：AIM:To screen a suspected Hungarian HNPCC family to find specific mutations and to evaluate their effect on the presentation of the disease. METHODS:The family was identified by applying the Amsterdam and Bethesda Criteria. Immunohistochemistry was performed, and DNA samples isolated from tumor tissue were evaluated f...

journal_title：World journal of gastroenterology

authors： Tanyi M,Olasz J,Lukács G,Csuka O,Tóth L,Szentirmay Z,Ress Z,Barta Z,Tanyi JL,Damjanovich L

更新日期：2006-02-28 00:00:00

abstract：AIM:To establish cell line and patient-derived xenograft (PDX) models for neuroendocrine carcinomas (NEC) which is highly desirable for gaining insight into tumor development as well as preclinical research including biomarker testing and drug response prediction. METHODS:Cell line establishment was conducted from dir...

journal_title：World journal of gastroenterology

authors： Gock M,Mullins CS,Harnack C,Prall F,Ramer R,Göder A,Krämer OH,Klar E,Linnebacher M

更新日期：2018-09-07 00:00:00

abstract：:Infection with hepatitis B virus is an important health problem worldwide: it affects more than 350 million people and is a leading cause of liver-related morbidity, accounting for 1 million deaths annually. Hepatic fibrosis is a consequence of the accumulation of extracellular matrix components in the liver. An accur...

journal_title：World journal of gastroenterology

authors： Enomoto M,Morikawa H,Tamori A,Kawada N

更新日期：2014-09-14 00:00:00

abstract：:A number of alterations have been found within the gut microbial profile of patients with inflammatory bowel diseases when compared with the healthy population; however, it is unclear whether such dysbiosis is the cause or simply the consequence of the disease state. In ulcerative colitis, the environment seems to pla...

journal_title：World journal of gastroenterology

authors： Sorrentino D

更新日期：2017-10-07 00:00:00

abstract：AIM:To examine the potency of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) as a hepatic heme oxygenase-1 (HO-1) inducer and its regulation in HepG2 cells. METHODS:Expression of HO-1 and NF-E2-related factor 2 (Nrf2) and activation of mitogen-activated protein (MAP) kinases were analyzed by Western blot, immunofluore...

journal_title：World journal of gastroenterology

authors： Pae HO,Oh GS,Jeong SO,Jeong GS,Lee BS,Choi BM,Lee HS,Chung HT

更新日期：2006-01-14 00:00:00

abstract：:Primary hepatic neuroendocrine tumor (PHNET) is an extremely rare liver tumor. Patients often have no clinical symptoms or have only non-specific symptoms, such as abdominal pain and abdominal mass. The clinical manifestations, disease development, treatment methods, and treatment outcomes of PHNET vary greatly among ...

journal_title：World journal of gastroenterology

authors： Meng XF,Pan YW,Wang ZB,Duan WD

更新日期：2018-06-28 00:00:00

abstract：:Although plasma cell infiltration is not rare in autopsy of patients with multiple myeloma (MM), it is very rarely detected in living patients. This is because MM rarely causes significant liver dysfunction that requires further evaluation. A 49-year-old man presented with acute renal failure and was diagnosed with ka...

journal_title：World journal of gastroenterology

authors： Rahhal FE,Schade RR,Nayak A,Coleman TA

更新日期：2009-04-28 00:00:00