Pedigree and genetic analysis of a novel mutation carrier patient suffering from hereditary nonpolyposis colorectal cancer.

abstract：AIM:To evaluate the proinflammatory effects and molecular mechanisms of interleukin (IL)-17 in intestinal epithelial cell line HT-29. METHODS:HT-29 cells were cultured with IL-17, tumor necrosis factor (TNF)-α, or the combination of both IL-17 and TNF-α. Real-time PCR and Western blot were used to measure the gene exp...

journal_title：World journal of gastroenterology

authors： Wang YL,Fang M,Wang XM,Liu WY,Zheng YJ,Wu XB,Tao R

更新日期：2014-12-21 00:00:00

abstract：:Celiac disease is an immune-mediated disorder that causes severe architectural disturbance in the small intestinal mucosa of genetically-predisposed individuals. Impaired absorption of multiple nutrients results and diarrhea and weight loss develop. Evidence has accumulated that a strict gluten-free diet can result in...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2017-04-21 00:00:00

abstract：:The progressive loss of efficacy of standard eradication therapies has made the treatment of Helicobacter pylori (H. pylori) more challenging than ever. Endoscopic-guided antibiotic susceptibility testing had previously been suggested to guide treatment after failure of second-line therapies. However, its role has exp...

journal_title：World journal of gastroenterology

authors： Cammarota G,Ianiro G,Bibbò S,Di Rienzo TA,Masucci L,Sanguinetti M,Gasbarrini A

更新日期：2014-05-14 00:00:00

abstract：:Although antagonists of tumor necrosis factor have resulted in major therapeutic benefits in inflammatory bowel disease, the magnitude and durability of response are variable. Similar to previously available drugs such as 5-aminosalicylates and immunomodulators, the therapeutic effect is not universal leaving many peo...

journal_title：World journal of gastroenterology

authors： Krishnareddy S,Swaminath A

更新日期：2014-02-07 00:00:00

abstract：:Mother-to-child transmission of hepatitis B virus (HBV) is among the most important causes of chronic HBV infection and is the commonest mode of transmission worldwide. Currently, the presence of HBsAg, HBeAg and HBV DNA in breast milk is confirmed. Several studies have reported that breastfeeding carries no additiona...

journal_title：World journal of gastroenterology

authors： Petrova M,Kamburov V

更新日期：2010-10-28 00:00:00

abstract：:We describe herein a 68-year-old woman who was diagnosed with a quite rare entity of intraductal papillary mucinous neoplasms (IPMNs) occurring simultaneously in the left lateral lobe of liver and the tail of pancreas. Abdominal computed tomography and magnetic resonance cholangiopancreatography showed a cystic dilata...

journal_title：World journal of gastroenterology

authors： Xu XW,Li RH,Zhou W,Wang J,Zhang RC,Chen K,Mou YP

更新日期：2012-11-28 00:00:00

abstract：:The management of intraductal papillary mucinous neoplasms (IPMN) is presently evolving as a result of the improved understanding of the natural history and biological behavior of the different pancreatic cystic neoplasms; and better preoperative diagnosis of these neoplasms due to advancement in preoperative diagnost...

journal_title：World journal of gastroenterology

authors： Goh BK

更新日期：2015-09-14 00:00:00

abstract：AIM:To assess CT, MR manifestations and their diagnostic value in hepatic tuberculosis. METHODS:CT findings in 12 cases and MR findings in 4 cases of hepatic tuberculosis proved by surgery or biopsy were retrospectively analyzed. RESULTS:(1) CT findings: One case of serohepatic type of hepatic tuberculosis had multip...

journal_title：World journal of gastroenterology

authors： Yu RS,Zhang SZ,Wu JJ,Li RF

更新日期：2004-06-01 00:00:00

abstract：AIM:To compare two different laparotomy methods for modeling rabbit VX2 hepatocarcinoma. METHODS:Thirty New Zealand rabbits were randomly divided into two groups: A and B. Group A was assigned a traditional laparotomy method (embedding tumor fragments directly into the liver with tweezers). Group B was subjected to an...

journal_title：World journal of gastroenterology

authors： Chen Z,Kang Z,Xiao EH,Tong M,Xiao YD,Li HB

更新日期：2015-04-28 00:00:00

abstract：AIM:To determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of capecitabine combined with postoperative radiotherapy for gastric cancer. METHODS:We enrolled patients with any T stage and node-positive gastroesophageal or gastric adenocarcinoma after complete resection with negative margins (R0) ...

journal_title：World journal of gastroenterology

authors： Wang X,Jin J,Li YX,Ren H,Fang H,Wang SL,Liu YP,Wang WH,Yu ZH,Song YW,Liu XF

更新日期：2014-01-28 00:00:00

abstract：:The incidence of gastric cancer remains high in South Korea. Upper gastrointestinal (GI) endoscopy, i.e., esophagogastroduodenoscopy (EGD), has a higher diagnostic specificity and sensitivity than the upper GI series. Additionally, EGD has the ability to biopsy, through taking a tissue of the pathologic lesion. Succes...

journal_title：World journal of gastroenterology

authors： Lee SH,Park YK,Cho SM,Kang JK,Lee DJ

更新日期：2015-01-21 00:00:00

abstract：:Helicobacter pylori (H. pylori) infection has been clearly linked to peptic ulcer disease and some gastrointestinal malignancies. Increasing evidence demonstrates possible associations to disease states in other organ systems, known as the extraintestinal manifestations of H. pylori. Different conditions associated wi...

journal_title：World journal of gastroenterology

authors： Wong F,Rayner-Hartley E,Byrne MF

更新日期：2014-09-14 00:00:00

abstract：AIM:To evaluate the accuracy of spot urinary Na/K and Na/creatinine (Cr) ratios as an alternative to 24-h urinary sodium in monitoring dietary compliance in patients with liver cirrhosis and ascites treated with diuretics. METHODS:The study was carried on 40 patients with liver cirrhosis and ascites treated with diure...

journal_title：World journal of gastroenterology

authors： El-Bokl MA,Senousy BE,El-Karmouty KZ,Mohammed Iel K,Mohammed SM,Shabana SS,Shalaby H

更新日期：2009-08-07 00:00:00

abstract：:Liver resection for hepatocellular carcinoma (HCC) is currently known to be a safer procedure than it was before because of technical advances and improvement in postoperative patient management and remains the first-line treatment for HCC in compensated cirrhosis. The aim of this review is to assess current indicatio...

journal_title：World journal of gastroenterology

authors： Gaillard M,Tranchart H,Dagher I

更新日期：2014-05-07 00:00:00

abstract：AIM:To compare the efficacy, improved quality of life, and prognosis in patients undergoing either subtotal colonic bypass with antiperistaltic cecoproctostomy (SCBAC) or subtotal colonic bypass plus colostomy with antiperistaltic cecoproctostomy (SCBCAC) for the treatment of slow transit constipation. METHODS:Between...

journal_title：World journal of gastroenterology

authors： Yang Y,Cao YL,Wang WH,Zhang YY,Zhao N,Wei D

更新日期：2018-06-21 00:00:00

abstract：AIM:To evaluate the optimal intervention point of a selective cyclooxygenase-2 (COX-2) inhibitor, celecoxib, for inhibiting Helicobacter pylori (H. pylori)-associated gastric carcinogenesis in Mongolian gerbils (MGs). METHODS:One hundred and twelve MGs were divided into six groups (A-F). One hundred gerbils were inocu...

journal_title：World journal of gastroenterology

authors： Kuo CH,Hu HM,Tsai PY,Wu IC,Yang SF,Chang LL,Wang JY,Jan CM,Wang WM,Wu DC

更新日期：2009-10-21 00:00:00

abstract：AIM:To determine whether absorbable sutures or non-absorbable sutures are better in preventing surgical site infection (SSI), in this paper we discuss the results of a randomized clinical trial which examined the type of sutures used during hepatectomy. METHODS:All hepatic resections performed from January 2007 to Nov...

journal_title：World journal of gastroenterology

authors： Harimoto N,Shirabe K,Abe T,Yukaya T,Tsujita E,Gion T,Kajiyama K,Nagaie T

更新日期：2011-05-14 00:00:00

abstract：AIM:To explore the mechanism of protection against acetaminophen-induced acute liver injury by Liuweiwuling tablets. METHODS:Intraperitoneal injections of acetaminophen (250 mg/kg) were used to induce acute liver injury in male C57BL/6 mice. A total of 24 healthy mice were randomly assigned to two groups: an acute liv...

journal_title：World journal of gastroenterology

authors： Lei YC,Li W,Luo P

更新日期：2015-07-14 00:00:00

abstract：AIM:To present a case of combined small bowel and reduced auxiliary liver transplantation. METHODS:A 55-year-old patient with short bowel syndrome and TPN-related liver dysfunction received small bowel transplantation combined with a reduced auxiliary liver graft. A liver was added to restore the patient's liver funct...

journal_title：World journal of gastroenterology

authors： Zhang WJ,Liu DG,Ye QF,Sha B,Zhen FJ,Guo H,Xia SS

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:The etiology of inflammatory bowel disease (IBD) is unknown, but it is believed to be multifactorial. The hygiene hypothesis proposes that better hygiene conditions would lead to less infectious disease during childhood and favor the development of immune-mediated diseases. AIM:To test the hygiene hypothesi...

journal_title：World journal of gastroenterology

authors： Salgado VCL,Luiz RR,Boéchat NLF,Leão IS,Schorr BDC,Parente JML,Lima DC,Silveira Júnior ES,Silva GOS,Almeida NP,Vieira A,de Bueno MLQ,Chebli JM,Bertges ÉR,Brugnara LMDC,Junqueira Neto C,Campbell SBG,Discacciati LL,Céza

更新日期：2020-07-07 00:00:00

abstract：AIM:to approach the relationship between alveolar echinococcosis (AE) pathology and level of sIL-2R,TNF-alpha and IFN-gamma in sera and the significance of cytokines in development of AE. METHODS:After 23 patients with AE were confirmed by ELISA and ultrasound, their sera were collected and the concentrations of sIL-2...

journal_title：World journal of gastroenterology

authors： Shi DZ,Li FR,Bartholomot B,Vuitton DA,Craig PS

更新日期：2004-12-15 00:00:00

abstract：AIM:To determine whether the expression profiles of EphB receptor and ephrin-B ligand can be used as markers for dysplastic/oncogenic transformation in gastric mucosa. METHODS:The protein expression and localization of EphB and ephrin-B in normal, ulcerated regenerating, and dysplastic gastric mucosa were examined in ...

journal_title：World journal of gastroenterology

authors： Uchiyama S,Saeki N,Ogawa K

更新日期：2015-01-14 00:00:00

abstract：:Management of acute diarrhea remains a global challenge, particularly in resource-limiting countries. Oral rehydration solution (ORS), a passive rehydrating therapy developed approximately 40 years ago, remains the mainstay treatment. Although ORS is effective for hydration, since it does not inhibit enterotoxin-media...

journal_title：World journal of gastroenterology

authors： Cheng SX

更新日期：2016-03-07 00:00:00

abstract：AIM:To investigate the effect of Jianweiyuyang (JWYY) granule on gastric ulcer recurrence and its mechanism in the treatment of gastric ulcer in rats. METHODS:Gastric ulcer in rats was induced according to Okeba's method with minor modification and the recurrence model was induced by IL-1beta. The expression of vascul...

journal_title：World journal of gastroenterology

authors： Dai XP,Li JB,Liu ZQ,Ding X,Huang CH,Zhou B

更新日期：2005-09-21 00:00:00

abstract：:Study of the effects of natural products, including traditional Chinese Medicines, on acetaminophen hepatotoxicity has gained considerable popularity in recent years, and some of them showed positive results and even promising therapeutic potentials. A recent report suggested that Liuweiwuling tablets protect against ...

journal_title：World journal of gastroenterology

authors： Du K,Jaeschke H

更新日期：2016-03-21 00:00:00

abstract：AIM:To evaluate the usefulness of contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) in differentiating between pancreatic adenocarcinomas and other pancreatic disease. METHODS:This retrospective cohort study evaluated 90 patients who were seen between November 2010 and May 2013. All these patients had solid pa...

journal_title：World journal of gastroenterology

authors： Park JS,Kim HK,Bang BW,Kim SG,Jeong S,Lee DH

更新日期：2014-01-14 00:00:00

abstract：AIM:To investigate the effects of autoantibodies against beta(1)-adrenoceptor in hepatitis virus myocarditis on action potential and L-type Ca(2+) currents. METHODS:Fifteen samples of autoantibodies against beta(1)-adrenoceptor positive sera of patients with hepatitis virus myocarditis were obtained and IgGs were puri...

journal_title：World journal of gastroenterology

authors： Liu K,Liao YH,Wang ZH,Li SL,Wang M,Zeng LL,Tang M

更新日期：2004-04-15 00:00:00

abstract：AIM:To evaluate the significance of hsp90alpha expression in human gastric cancer tissues. METHODS:Immunohistochemical staining was used in clinical specimens from 33 cases of gastric cancer and 33 cases of gastritis with rabbit anti-human hsp90alpha multi-clonal antibody in order to explore the relationship between t...

journal_title：World journal of gastroenterology

authors： Zuo DS,Dai J,Bo AH,Fan J,Xiao XY

更新日期：2003-11-01 00:00:00

abstract：:Patients with ulcerative colitis (UC) and Crohn's disease (CD) are at increased risk for developing colorectal cancer (CRC), and this is believed to be a result of chronic inflammation. Although conclusive evidence is still missing, both epidemiological and experimental observations suggest that certain drugs used to ...

journal_title：World journal of gastroenterology

authors： Stolfi C,Pellegrini R,Franze E,Pallone F,Monteleone G

更新日期：2008-07-28 00:00:00

abstract：:Hepatitis B virus (HBV) infection is still the most common cause of hepatocellular carcinoma and liver cirrhosis world wide. Recently, however, there has been quite dramatic improvement in the understanding of HBV associated liver disease and its treatment. It has become clear that high viral replication is a major ri...

journal_title：World journal of gastroenterology

authors： Tillmann HL

更新日期：2007-01-07 00:00:00