Abstract:
AIM:To present a case of combined small bowel and reduced auxiliary liver transplantation. METHODS:A 55-year-old patient with short bowel syndrome and TPN-related liver dysfunction received small bowel transplantation combined with a reduced auxiliary liver graft. A liver was added to restore the patient's liver function and to protect the intestinal allograft from rejection. His own liver was not removed. RESULTS:Without donor pretreatment and by conventional immunosuppresive therapy following transplantation, the patient experienced had only one episode of mild intestinal rejection, which was easily reversed by treatment with Methylprednisolone. No liver rejection occurred. Unfortunately, the patient died of heart and lung failure 30d after transplantation, despite successful graft replacement. Histopathologic examination of specimens after death demonstrated normal structure in both intestinal and liver grafts. CONCLUSION:The auxiliary liver graft might play a role in preventing intestinal allograft rejection. However, the observation period in this case is short. Further study is needed to determine the risks, effect on the protecting the small-bowel from rejection, and feasibility of general application of this procedure.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Zhang WJ,Liu DG,Ye QF,Sha B,Zhen FJ,Guo H,Xia SSdoi
10.3748/wjg.v8.i5.956keywords:
subject
Has Abstractpub_date
2002-10-01 00:00:00pages
956-60issue
5eissn
1007-9327issn
2219-2840journal_volume
8pub_type
杂志文章abstract:AIM:To determine the association of circulating miR-125a/b expression with the risk and disease severity of Crohn's disease (CD), and with inflammatory cytokines. METHODS:Plasma samples were collected from patients with active CD (A-CD), or CD in remission (R-CD) and from healthy controls (HCs). The levels of the infl...
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pub_type: 临床试验,杂志文章
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pub_type: 评论,信件
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doi:10.3748/wjg.15.4392
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pub_type: 杂志文章,评审
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pub_type: 评论,信件
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pub_type: 杂志文章
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pub_type: 杂志文章,多中心研究
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doi:10.3748/wjg.v12.i32.5186
更新日期:2006-08-28 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章
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journal_title:World journal of gastroenterology
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pub_type: 杂志文章
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journal_title:World journal of gastroenterology
pub_type: 杂志文章
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更新日期:2007-02-21 00:00:00
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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更新日期:2004-04-01 00:00:00