Characteristics of non-erosive gastroesophageal reflux disease refractory to proton pump inhibitor therapy.

abstract：AIM:To study the effects of Changtai granules (CTG), a traditional compound Chinese medicine, on chronic trinitrobenzene sulfonic acid-induced colitis in rats. METHODS:Healthy adult Sprague-Dawley (SD) rats of both sexes, weighing 250-300 g, were employed in the present study. The rat colitis models were induced by 2,...

journal_title：World journal of gastroenterology

authors： Cao YB,Zhang JD,Diao YY,Yan L,Wang DJ,Jia XM,Gao PH,Cheng MH,Xu Z,Wang Y,Jiang YY

更新日期：2005-06-21 00:00:00

abstract：AIM:To study the effect of probiotics on interleukin-8 secretion in intestinal epithelia when stimulated by proinflammatory cytokines. METHODS:Colonic adenocarcinoma HT29 cells were cultured and divided into four groups: control, TNF-alpha (group T in short), bifidobacterium (group B), lactobacillus (group L). B. Long...

journal_title：World journal of gastroenterology

authors： Bai AP,Ouyang Q,Zhang W,Wang CH,Li SF

更新日期：2004-02-01 00:00:00

abstract：AIM:To observe the preventive effects of combined therapy of AMD (allantoin, metronidazolem and dexamethasone in combination) on intra-abdominal adhesion in dogs. METHODS:20 dogs of both sexes were used in this study. After laparotomy under anesthesia, 2 cm section of cecal end was clamped and ligated, then 1 cm cecum...

journal_title：World journal of gastroenterology

authors： Wang XC,Gui CQ,Zheng QS

更新日期：2003-03-01 00:00:00

abstract：AIM:To assess the efficacy and safety of fourth-generation quinolones for Helicobacter pylori (H. pylori) eradication, we conducted this systematic review and meta-analysis of randomized clinical trials. METHODS:Major literature databases (PubMed, EMBASE and the Cochrane Central Register of Controlled Trials) were sea...

journal_title：World journal of gastroenterology

authors： An Y,Wang Y,Wu S,Wang YH,Qian X,Li Z,Fu YJ,Xie Y

更新日期：2018-08-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common and highly fatal malignancies worldwide. Chronic infection with hepatitis B virus (HBV) is a major cause of HCC. High HBV replication rate and related non-resolving inflammation are the major risk factors of HCC occurrence and postoperative recurrence. Early pro...

journal_title：World journal of gastroenterology

authors： Du Y,Han X,Ding YB,Yin JH,Cao GW

更新日期：2016-08-07 00:00:00

abstract：:Multiple studies have demonstrated alterations in the intestinal microbial community (termed the microbiome) in Crohn's disease (CD) and several lines of evidence suggest these changes may have a significant role in disease pathogenesis. In active and quiescent disease, both the faecal and mucosa-associated microbiome...

journal_title：World journal of gastroenterology

authors： Tawfik A,Flanagan PK,Campbell BJ

更新日期：2014-07-21 00:00:00

abstract：AIM:To investigate that both the neuronal function of the contractile system and structural apparatus of the gastrointestinal tract are affected in patients with longstanding diabetes and auto mic neuropathy. METHODS:The evoked esophageal and duodenal contractile activity to standardized bag distension was assessed us...

journal_title：World journal of gastroenterology

authors： Frokjaer JB,Andersen SD,Ejskjaer N,Funch-Jensen P,Drewes AM,Gregersen H

更新日期：2007-09-28 00:00:00

abstract：AIM:To explore the cooperative effects of antisense oligonucleotide (ASON) of cell adhesion molecules and cimetidine on the expression of E-selectin and ICAM-1 in endothelial cells and their adhesion to tumor cells. METHODS:After treatment of endothelial cells with ASON and/or cimetidine and induction with TNF-alpha, ...

journal_title：World journal of gastroenterology

authors： Tang NH,Chen YL,Wang XQ,Li XJ,Yin FZ,Wang XZ

更新日期：2004-01-01 00:00:00

abstract：AIM:To observe whether there are differences in the effects of electro-acupuncture (EA) and moxibustion (Mox) in rats with visceral hypersensitivity. METHODS:EA at 1 mA and 3 mA and Mox at 43 °C and 46 °C were applied to the Shangjuxu (ST37, bilateral) acupoints in model rats with visceral hypersensitivity. Responses ...

journal_title：World journal of gastroenterology

authors： Zhao JM,Li L,Chen L,Shi Y,Li YW,Shang HX,Wu LY,Weng ZJ,Bao CH,Wu HG

更新日期：2017-04-28 00:00:00

abstract：:Most medical specialties including the field of gastroenterology are mainly aimed at treating diseases rather than preventing them. Genomic medicine studies the health/disease process based on the interaction of the human genes with the environment. The gastrointestinal (GI) system is an ideal model to analyze the int...

journal_title：World journal of gastroenterology

authors： Panduro A,Rivera-Iñiguez I,Sepulveda-Villegas M,Roman S

更新日期：2017-05-07 00:00:00

abstract：AIM:To investigate and compare the hepatogenic transdifferentiation of adipose tissue-derived stem cells (ADSC) and bone marrow-derived mesenchymal stem cells (BMSC) in vitro. Transdifferentiation of BMSC into hepatic cells in vivo has been described. Adipose tissue represents an accessible source of ADSC, with similar...

journal_title：World journal of gastroenterology

authors： Taléns-Visconti R,Bonora A,Jover R,Mirabet V,Carbonell F,Castell JV,Gómez-Lechón MJ

更新日期：2006-09-28 00:00:00

abstract：:Heterotopic pancreatic tissue within the stomach is rare and dysplasia within heterotopic pancreatic tissue is very rare. We present the first report of a patient with concurrent occurrence of heterotopic pancreas in the stomach with a gastrointestinal stromal tumour. ...

journal_title：World journal of gastroenterology

authors： Kaufman A,Storey D,Lee CS,Murali R

更新日期：2007-11-21 00:00:00

abstract：:Infection with hepatitis B virus is an important health problem worldwide: it affects more than 350 million people and is a leading cause of liver-related morbidity, accounting for 1 million deaths annually. Hepatic fibrosis is a consequence of the accumulation of extracellular matrix components in the liver. An accur...

journal_title：World journal of gastroenterology

authors： Enomoto M,Morikawa H,Tamori A,Kawada N

更新日期：2014-09-14 00:00:00

abstract：AIM:To further elucidate the pathogenesis and mechanisms of the high risk of gallstone formation in Crohn's disease. METHODS:Gallbladder bile was obtained from patients with Crohn's disease who were admitted for elective surgery (17 with ileal/ileocolonic disease and 7 with Crohn's colitis). Fourteen gallstone patient...

journal_title：World journal of gastroenterology

authors： Lapidus A,Akerlund JE,Einarsson C

更新日期：2006-01-07 00:00:00

abstract：AIM:To investigate the effects of adeno-associated virus (AAV) mediated expression of human interferon-gamma for gene therapy in experimental hepatic fibrosis in vitro and in vivo. METHODS:We constructed the recombinant AAV encoding human INF-gamma (rAAV- INF-gamma) and took the primary rat hepatic stellate cells and ...

journal_title：World journal of gastroenterology

authors： Chen M,Wang GJ,Diao Y,Xu RA,Xie HT,Li XY,Sun JG

更新日期：2005-07-14 00:00:00

abstract：:The occurrence of pancreatic pleural effusion, secondary to an internal pancreatic fistula, is a rare clinical syndrome and diagnosis is often missed. The key to the diagnosis is a dramatically elevated pleural fluid amylase. This pancreatic pleural effusion is also called a pancreatic pleural fistula. It is character...

journal_title：World journal of gastroenterology

authors： Jin SG,Chen ZY,Yan LN,Zeng Y

更新日期：2010-09-21 00:00:00

abstract：AIM:To evaluate the risk factors for ampullary adenoma and ampullary cancer. METHODS:This case-control study included ampullary tumor patients referred to Peking Union Medical College Hospital. Controls were randomly selected from an existing database of healthy individuals at the Health Screening Center of the same h...

journal_title：World journal of gastroenterology

authors： He XD,Wu Q,Liu W,Hong T,Li JJ,Miao RY,Zhao HT

更新日期：2014-07-28 00:00:00

abstract：:We have read with interest the paper by Roman C. and colleagues discussing the relationship between gastroesophageal reflux disease and atrial fibrillation. The review is presenting the available evidence for the common pathogenic mechanisms. However, from a cardiologist perspective, some available data were not highl...

journal_title：World journal of gastroenterology

authors： Floria M,Drug VL

更新日期：2015-03-14 00:00:00

abstract：AIM:To investigate the efficacy and safety of gemcitabine (Gem)-based combination chemotherapies for the treatment of advanced biliary tract cancer. METHODS:Clinical trials were identified by searching scientific literature databases (PubMed, EMBASE and the Cochrane Library) for studies published between 1975 and 2013...

journal_title：World journal of gastroenterology

authors： Liu H,Zhang QD,Li ZH,Zhang QQ,Lu LG

更新日期：2014-12-21 00:00:00

abstract：:Liver regeneration after major surgery may activate occult micrometastases and facilitate tumor growth, leading to liver tumor recurrence. Molecular changes during liver regeneration can provide a microenvironment that stimulates intrahepatic tumor propagation through alterations in cellular signaling pathways, where ...

journal_title：World journal of gastroenterology

authors： Shi JH,Line PD

更新日期：2014-11-21 00:00:00

abstract：AIM:To evaluate the diagnostic value of gadobenate dimeglumine (Gd-BOPTA)-enhanced hepatocyte-phase magnetic resonance imaging (MRI) in evaluating hepatic fibrosis and hepatitis. METHODS:Hepatocyte-phase images of Gd-BOPTA-enhanced MRI were retrospectively evaluated in 76 patients with chronic liver disease. These pat...

journal_title：World journal of gastroenterology

authors： Li XM,Chen Z,Xiao EH,Shang QL,Ma C

更新日期：2017-05-07 00:00:00

abstract：AIM:To determine the prognostic significance of isolated tumor cells (ITCs) and lymph node micrometastases in gastric cancer. METHODS:Hematoxylin and eosin-stained slides of lymph node dissections of 632 consecutive gastric cancers were reviewed. Cytokeratin immunostaining was performed in 280 node-negative cases and ...

journal_title：World journal of gastroenterology

authors： Lee HS,Kim MA,Yang HK,Lee BL,Kim WH

更新日期：2005-10-14 00:00:00

abstract：AIM:To investigate disease-specific gene expression profiles of peripheral blood mononuclear cells (PBMCs) from Crohn's disease (CD) patients in clinical remission. METHODS:Patients with CD in clinical remission or with very low disease activity according to the Crohn's disease activity index were genotyped regarding ...

journal_title：World journal of gastroenterology

authors： Schäffler H,Rohde M,Rohde S,Huth A,Gittel N,Hollborn H,Koczan D,Glass Ä,Lamprecht G,Jaster R

更新日期：2018-03-21 00:00:00

abstract：AIM:To investigate the effect of schisandrin B (Sch B) on proliferation and apoptosis of human hepatoma SMMC-7721 cells in vitro and regulation of Hsp70 and Caspases-3, 7, 9 expression by Sch B. METHODS:Human hepatoma cell line SMMC-7721 was cultured and treated with Sch B at various concentrations. Growth suppression...

journal_title：World journal of gastroenterology

authors： Wu YF,Cao MF,Gao YP,Chen F,Wang T,Zumbika EP,Qian KX

更新日期：2004-10-15 00:00:00

abstract：AIM:To assess whether the use of fibrin sealant shortens the closure time of postoperative enterocutaneous fistulas (ECFs). METHODS:The prospective case-control study included 70 patients with postoperative ECFs with an output of < 500 mL/d, a fistulous tract of > 2 cm and without any local complication. They were div...

journal_title：World journal of gastroenterology

authors： Avalos-González J,Portilla-deBuen E,Leal-Cortés CA,Orozco-Mosqueda A,Estrada-Aguilar Mdel C,Velázquez-Ramírez GA,Ambriz-González G,Fuentes-Orozco C,Guzmán-Gurrola AE,González-Ojeda A

更新日期：2010-06-14 00:00:00

abstract：AIM:To analyze the safety and efficiency of direct-acting antiviral (DAA) regimens in liver-transplanted patients with hepatitis C virus (HCV) reinfection. METHODS:Between January 2014 and December 2016, 39 patients with HCV reinfection after liver transplantation were treated at our tertiary referral center with sofo...

journal_title：World journal of gastroenterology

authors： Rupp C,Hippchen T,Neuberger M,Sauer P,Pfeiffenberger J,Stremmel W,Gotthardt DN,Mehrabi A,Weiss KH

更新日期：2018-03-28 00:00:00

abstract：AIM:To investigate whether illness severity has an impact on gastric residual volume (GRV) in medical critically ill patients. METHODS:Medical intensive care unit (ICU) patients requiring nasogastric feeding were enrolled. Sequential Organ Failure Assessment (SOFA) score was assessed immediately preceding the start of...

journal_title：World journal of gastroenterology

authors： Hsu CW,Sun SF,Lee DL,Lin SL,Wong KF,Huang HH,Li HJ

更新日期：2011-04-21 00:00:00

abstract：BACKGROUND:Pit pattern classification using magnifying chromoendoscopy is the established method for diagnosing colorectal lesions. The Japan Narrow-band-imaging (NBI) Expert Team (JNET) classification is a novel NBI magnifying endoscopic classification that focuses on the vessel, and surface patterns. AIM:To determin...

journal_title：World journal of gastroenterology

authors： Zhang Y,Chen HY,Zhou XL,Pan WS,Zhou XX,Pan HH

更新日期：2020-10-28 00:00:00

abstract：BACKGROUND:Irritable bowel syndrome (IBS) is a common chronic non-organic disease of the digestive system. Berberine (BBR) has been used to treat patients with IBS, but the underlying therapeutic mechanism is little understood. We believe that BBR achieves its therapeutic effect on IBS by preventing stress intestinal i...

journal_title：World journal of gastroenterology

authors： Yu ZC,Cen YX,Wu BH,Wei C,Xiong F,Li DF,Liu TT,Luo MH,Guo LL,Li YX,Wang LS,Wang JY,Yao J

更新日期：2019-08-07 00:00:00

abstract：:The diagnosis of herbal hepatotoxicity or herb induced liver injury (HILI) represents a particular clinical and regulatory challenge with major pitfalls for the causality evaluation. At the day HILI is suspected in a patient, physicians should start assessing the quality of the used herbal product, optimizing the clin...

journal_title：World journal of gastroenterology

authors： Teschke R,Frenzel C,Schulze J,Eickhoff A

更新日期：2013-05-21 00:00:00