Reduction of the closure time of postoperative enterocutaneous fistulas with fibrin sealant.

Abstract:

AIM:To assess whether the use of fibrin sealant shortens the closure time of postoperative enterocutaneous fistulas (ECFs). METHODS:The prospective case-control study included 70 patients with postoperative ECFs with an output of < 500 mL/d, a fistulous tract of > 2 cm and without any local complication. They were divided into study (n = 23) and control groups (n = 47). Esophageal, gastric and colocutaneous fistulas were monitored under endoscopic visualization, which also allowed fibrin glue application directly through the external hole. Outcome variables included closure time, time to resume oral feeding and morbidity related to nutritional support. RESULTS:There were no differences in mean age, fistula output, and follow-up. Closure-time for all patients of the study group was 12.5 +/- 14.2 d and 32.5 +/- 17.9 d for the control group (P < 0.001), and morbidity related to nutritional support was 8.6% and 42.5%, respectively (P < 0.01). In patients with colonic fistulas, complete closure occurred 23.5 +/- 19.5 d after the first application of fibrin glue, and spontaneous closure was observed after 36.2 +/- 22.8 d in the control group (P = 0.36). Recurrences were observed in 2 patients because of residual disease. One patient of each group died during follow-up as a consequence of septic complications related to parenteral nutrition. CONCLUSION:Closure time was significantly reduced with the use of fibrin sealant, and oral feeding was resumed faster. We suggest the use of fibrin sealant for the management of stable enterocutaneous fistulas.

journal_name

World J Gastroenterol

authors

Avalos-González J,Portilla-deBuen E,Leal-Cortés CA,Orozco-Mosqueda A,Estrada-Aguilar Mdel C,Velázquez-Ramírez GA,Ambriz-González G,Fuentes-Orozco C,Guzmán-Gurrola AE,González-Ojeda A

doi

10.3748/wjg.v16.i22.2793

subject

Has Abstract

pub_date

2010-06-14 00:00:00

pages

2793-800

issue

22

eissn

1007-9327

issn

2219-2840

journal_volume

16

pub_type

杂志文章
  • Technical skills and training of upper gastrointestinal endoscopy for new beginners.

    abstract::The incidence of gastric cancer remains high in South Korea. Upper gastrointestinal (GI) endoscopy, i.e., esophagogastroduodenoscopy (EGD), has a higher diagnostic specificity and sensitivity than the upper GI series. Additionally, EGD has the ability to biopsy, through taking a tissue of the pathologic lesion. Succes...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v21.i3.759

    authors: Lee SH,Park YK,Cho SM,Kang JK,Lee DJ

    更新日期:2015-01-21 00:00:00

  • Hepatitis C virus RNA detection in serum and peripheral blood mononuclear cells of patients with hepatitis C.

    abstract:AIM:To investigate the existence and clinical significance of hepatitis C virus (HCV) RNA in the serum and peripheral blood mononuclear cells (PBMC) of patients with hepatitis C. METHODS:HCV RNA was detected by nested polymerase chain reaction (Nested PCR) in serum and in PBMC of 46 patients with acute hepatitis C (AH...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v3.i2.108

    authors: Zhou P,Cai Q,Chen YC,Zhang MS,Guan J,Li XJ

    更新日期:1997-06-15 00:00:00

  • Value of mink vomit model in study of anti-emetic drugs.

    abstract:AIM:To establish a new, reliable vomit model of minks. METHODS:Adult male minks were randomly divided into 8 groups (n=6): cisplatin (7.5 mg/kg) intraperitoneal injection (i.p.) group, copper sulfate (40 mg/kg) intragastric injection (i.g.) group, apomorphine (1.6 mg/kg) subcutaneous injection (s.c.) group, and 18 Gy ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i8.1300

    authors: Zhang F,Wang L,Yang ZH,Liu ZT,Yue W

    更新日期:2006-02-28 00:00:00

  • Fenofibrate for patients with asymptomatic primary biliary cirrhosis.

    abstract:AIM:Primary biliary cirrhosis (PBC) is a chronic, cholestatic disease of autoimmune etiology, the histology of which shows a destruction of the intrahepatic bile duct and portal inflammation. Ursodeoxycholic acid (UDCA) is now used as a first-line drug for asymptomatic PBC (aPBC) because it is reported that UDCA decrea...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v10.i6.894

    authors: Dohmen K,Mizuta T,Nakamuta M,Shimohashi N,Ishibashi H,Yamamoto K

    更新日期:2004-03-15 00:00:00

  • Endoscopic management of intragastric penetrated adjustable gastric band for morbid obesity.

    abstract::This report describes a case of successful endoscopic management of intragastric penetrated adjustable gastric band in a patient with morbid obesity. The favorable course of the case described here demonstrates that adjustable gastric bands in the process of migration need not be removed surgically in patients who are...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i25.4098

    authors: De Palma GD,Formato A,Pilone V,Rega M,Giuliano ME,Simeoli I,Forestieri P

    更新日期:2006-07-07 00:00:00

  • Association of genetic polymorphisms of aldehyde dehydrogenase-2 with esophageal squamous cell dysplasia.

    abstract:AIM:To demonstrate the possible associations between genetic polymorphisms of aldehyde dehydrogenase-2 (ALDH2) and esophageal squamous cell dysplasia (ESCD). METHODS:All participants came from an area of high incidence of esophageal cancer and underwent an endoscopic staining examination; biopsies were taken from a no...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i27.3445

    authors: Zhou YZ,Diao YT,Li H,Li HQ,Ma Q,Cui J

    更新日期:2010-07-21 00:00:00

  • Evaluation and management of patients with refractory ascites.

    abstract::Some patients with ascites due to liver cirrhosis become no longer responsive to diuretics. Once other causes of ascites such as portal vein thrombosis, malignancy or infection and non-compliance with medications and low sodium diet have been excluded, the diagnosis of refractory ascites can be made based on strict cr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.15.67

    authors: Senousy BE,Draganov PV

    更新日期:2009-01-07 00:00:00

  • Penicillium marneffei chylous ascites in acquired immune deficiency syndrome: a case report.

    abstract::Penicillium marneffei (P. marneffei) infection usually occurs with skin, bone marrow, lung or hepatic involvement. However, no cases of P. marneffei infection with chylous ascites have been reported thus far. In this report, we describe the first case of acquired immune deficiency syndrome (AIDS) which has been compli...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i37.5312

    authors: Shen YZ,Wang ZY,Lu HZ

    更新日期:2012-10-07 00:00:00

  • Trocar-related abdominal wall bleeding in 200 patients after laparoscopic cholecistectomy: Personal experience.

    abstract:AIM:To determine the complications and incidence of the first and second access-related vascular injuries induced by videolaparoscopic cholecistectomy. METHODS:We retrospectively reviewed vascular injuries in 200 consecutive patients who underwent videolaparoscopic cholecistectomy from 2003 to 2005. One hundred and on...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i44.7165

    authors: Geraci G,Sciume C,Pisello F,Li Volsi F,Facella T,Modica G

    更新日期:2006-11-28 00:00:00

  • Infections with Helicobacter pylori and challenges encountered in Africa.

    abstract::Helicobacter pylori (H. pylori) is the causative agent of gastritis, peptic ulcer disease, mucosa associated lymphoid tissue lymphoma and gastric cancer (GC). While this bacterium infects 50% of the world's population, in Africa its prevalence reach as high as 80% as the infection is acquired during childhood. Risk fa...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v25.i25.3183

    authors: Smith S,Fowora M,Pellicano R

    更新日期:2019-07-07 00:00:00

  • Pancreatic necrosis and severity are independent risk factors for pancreatic endocrine insufficiency after acute pancreatitis: A long-term follow-up study.

    abstract:BACKGROUND:Pancreatic endocrine insufficiency after acute pancreatitis (AP) has drawn increasing attention in recent years. AIM:To assess the impact of risk factors on the development of pancreatic endocrine insufficiency after AP. METHODS:This retrospective observational long-term follow-up study was conducted in a ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i23.3260

    authors: Yu BJ,Li NS,He WH,He C,Wan JH,Zhu Y,Lu NH

    更新日期:2020-06-21 00:00:00

  • Prevalence of IgA-antiendomysial antibody in a patient cohort with idiopathic low bone mineral density.

    abstract:AIM:To investigate the frequency of serum IgA-antiendomysial antibody positivity in patients with low bone mineral density and to assess the risk group for screening of celiac disease. METHODS:One hundred and thirty-five patients (14 male, 121 female) with idiopathic low bone mineral density were evaluated. The median...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i21.2978

    authors: Karakan T,Ozyemisci-Taskiran O,Gunendi Z,Atalay F,Tuncer C

    更新日期:2007-06-07 00:00:00

  • A newly designed big cup nitinol stent for gastric outlet obstruction.

    abstract:AIM:To find out whether a newly designed big cup nitinol stent is suitable for treatment of patients with gastric outlet obstruction resulting from gastric cancer. METHODS:The new stent is composed of a proximal big cup segment (20 mm in length and 48-55 mm in diameter), a middle part (60 mm in length and 20 mm in dia...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i33.4206

    authors: Shi D,Liao SH,Geng JP

    更新日期:2010-09-07 00:00:00

  • Hepatitis C virus may infect extrahepatic tissues in patients with hepatitis C.

    abstract::AIM:To explore the status of extrahepatic hepatitis C virus (HCV) infection and replication in hepatitis C patients,and its potential implication in HCV infection and pathogenicity.METHODS:By reverse-transcriptase poly-merase chain reaction (RT-PCR),in situ hybridization (ISH) and immunohis-tochemistry, HCV RNA, HCV r...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v6.i6.805

    authors: Yan FM,Chen AS,Hao F,Zhao XP,Gu CH,Zhao LB,Yang DL,Hao LJ

    更新日期:2000-12-01 00:00:00

  • Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.

    abstract:AIM:To reviewing genetic and epigenetic make-up of metastatic colorectal cancers (mCRCs) addicted to epidermal growth factor receptor (EGFR) signalling. METHODS:The present study summarizes the potential value of prognostic and predictive biomarkers in selecting mCRC patients treated with anti-EGFR therapy. A meta-ana...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i30.6944

    authors: Lo Nigro C,Ricci V,Vivenza D,Granetto C,Fabozzi T,Miraglio E,Merlano MC

    更新日期:2016-08-14 00:00:00

  • Hepatitis C virus: virology, diagnosis and management of antiviral therapy.

    abstract::Hepatitis C virus (HCV) infects approximately 170 million individuals worldwide. Prevention of HCV infection complications is based on antiviral therapy with the combination of pegylated interferon alfa and ribavirin. The use of serological and virological tests has become essential in the management of HCV infection ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v13.i17.2461

    authors: Chevaliez S,Pawlotsky JM

    更新日期:2007-05-07 00:00:00

  • Stronger inhibition of gastric acid secretion by lafutidine, a novel H2 receptor antagonist, than by the proton pump inhibitor lansoprazole.

    abstract:AIM:To compare the antisecretory activity and plasma drug concentrations of a single oral dose of 10 mg lafutidine, a novel H2 receptor antagonist, with those of the proton pump inhibitor lansoprazole (LPZ) 30 mg. METHODS:Ten volunteers without H pylori infection participated in this crossover study comparing lafutidi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.14.2406

    authors: Yamagishi H,Koike T,Ohara S,Horii T,Kikuchi R,Kobayashi S,Abe Y,Iijima K,Imatani A,Suzuki K,Hishinuma T,Goto J,Shimosegawa T

    更新日期:2008-04-21 00:00:00

  • Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning.

    abstract:AIM:To investigate the role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning (IPC). METHODS:A rat model of acute hepatic ischemia-reperfusion was established, 24 healthy male Wistar rats were randomly divided into sham-operated group, ische...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i13.1934

    authors: Sun K,Liu ZS,Sun Q

    更新日期:2004-07-01 00:00:00

  • Correlation of Chlamydia pneumoniae infection with primary biliary cirrhosis.

    abstract:AIM:To evaluate the association between Chlamydia pneumoniae (Cpn) infection and primary biliary cirrhosis (PBC). METHODS:Cpn IgG and IgM were determined by enzyme-linked immunosorbent assay (ELISA) in 41 well-established PBC patients and two race-matched control groups (post-hepatitis cirrhosis, n = 70; healthy contr...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i26.4108

    authors: Liu HY,Deng AM,Zhang J,Zhou Y,Yao DK,Tu XQ,Fan LY,Zhong RQ

    更新日期:2005-07-14 00:00:00

  • Expression of mucins and E-cadherin in gastric carcinoma and their clinical significance.

    abstract:AIM:To investigate the expression of three types of mucin (MUC1, MUC2, MUC5AC) and E-cadherin in human gastric carcinomas and their clinical significance. METHODS:Ninety-four gastric cancer specimens were classified according to WHO criteria and detected by immunohistochemical assay of expression of mucins and E-cadhe...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i20.3044

    authors: Zhang HK,Zhang QM,Zhao TH,Li YY,Yi YF

    更新日期:2004-10-15 00:00:00

  • Group II p21-activated kinases as therapeutic targets in gastrointestinal cancer.

    abstract::P21-activated kinases (PAKs) are central players in various oncogenic signaling pathways. The six PAK family members are classified into group I (PAK1-3) and group II (PAK4-6). Focus is currently shifting from group I PAKs to group II PAKs. Group II PAKs play important roles in many fundamental cellular processes, som...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i3.1224

    authors: Shao YG,Ning K,Li F

    更新日期:2016-01-21 00:00:00

  • Hepatitis C virus in Pakistan: a systematic review of prevalence, genotypes and risk factors.

    abstract::In Pakistan more than 10 million people are living with Hepatitis C virus (HCV), with high morbidity and mortality. This article reviews the prevalence, genotypes and factors associated with HCV infection in the Pakistani population. A literature search was performed by using the keywords; HCV prevalence, genotypes an...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.15.5647

    authors: Waheed Y,Shafi T,Safi SZ,Qadri I

    更新日期:2009-12-07 00:00:00

  • Prognostic factors in patients with advanced cholangiocarcinoma: role of surgery, chemotherapy and body mass index.

    abstract:AIM:To study the factors that may affect survival of cholangiocarcinoma in Lebanon. METHODS:A retrospective review of the medical records of 55 patients diagnosed with cholangio-carcinoma at the American University of Beirut between 1990 and 2005 was conducted. Univariate and multivariate analyses were performed to de...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.3224

    authors: Farhat MH,Shamseddine AI,Tawil AN,Berjawi G,Sidani C,Shamseddeen W,Barada KA

    更新日期:2008-05-28 00:00:00

  • Case of pediatric traditional serrated adenoma resected via endoscopic submucosal dissection.

    abstract::Traditional serrated adenoma (TSA) is a type of serrated polyp of the colorectum and is thought to be a precancerous lesion. There are three types of serrated polyps, namely, hyperplastic polyps, sessile serrated adenomas/polyps, and TSAs. TSA is the least common of the three types and accounts for about 5% of serrate...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i24.4462

    authors: Kondo S,Mori H,Nishiyama N,Kondo T,Shimono R,Okada H,Kusaka T

    更新日期:2017-06-28 00:00:00

  • Risk factors and outcome of bacterial infections in cirrhosis.

    abstract::Viable and non-viable pathological bacterial translocation promote a self-perpetuating circle of dysfunctional immune activation and systemic inflammation facilitating infections and organ failure in advanced cirrhosis. Bacterial infections and sepsis are now recognized as a distinct stage in the natural progression o...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i10.2542

    authors: Bruns T,Zimmermann HW,Stallmach A

    更新日期:2014-03-14 00:00:00

  • Impact of alcohol on hepatitis C virus replication and interferon signaling.

    abstract::Hepatitis C virus (HCV) is one of the main etiological factors responsible for liver disease worldwide. It has been estimated that there are over 170 million people infected with HCV worldwide. Of these infected individuals, approximately 75% will go on to develop a life long necroinflammatory liver disease, which ove...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v16.i11.1337

    authors: McCartney EM,Beard MR

    更新日期:2010-03-21 00:00:00

  • Effects of glutamine on intestinal permeability and bacterial translocation in TPN-rats with endotoxemia.

    abstract:AIM:To evaluate the protective effect and mechanism of glutamine on the intestinal barrier function in total parenteral nutrition (TPN) rats with trauma or endotoxemia. METHODS:To perform prospective, randomized and controlled animal experimentation of rats with surgical trauma, TPN and endotoxemia, thirty-four male, ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v9.i6.1327

    authors: Ding LA,Li JS

    更新日期:2003-06-01 00:00:00

  • Expression of some tumor associated factors in human carcinogenesis and development of gastric carcinoma.

    abstract:AIM:To study the effect of IGF-1/IGF-1R and gastrin/CCK-BR on carcinogenesis and development of human gastric carcinoma and to explore its mechanism and provide a credible theoretical foundation for early diagnosis and molecular therapy of gastric carcinoma. METHODS:mRNA expression levels of IGF-1/IGF-1R and gastrin/C...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i21.3217

    authors: Zhao MD,Hu XM,Sun DJ,Zhang Q,Zhang YH,Meng W

    更新日期:2005-06-07 00:00:00

  • Role of succinate dehydrogenase deficiency and oncometabolites in gastrointestinal stromal tumors.

    abstract::Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. At the molecular level, GISTs can be categorized into two groups based on the causative oncogenic mutations. Approximately 85% of GISTs are caused by gain-of-function mutations in the tyrosine kinase receptor ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v26.i34.5074

    authors: Zhao Y,Feng F,Guo QH,Wang YP,Zhao R

    更新日期:2020-09-14 00:00:00

  • Long-term natural history of Crohn's disease.

    abstract::Crohn's disease is a chronic inflammatory granulomatous process that usually involves different sites in the intestinal tract. Genetic and environmental factors are thought to play a role in its etiology and pathogenesis. The disorder has a heterogeneous clinical expression and data from tertiary care settings have do...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.1315

    authors: Freeman HJ

    更新日期:2009-03-21 00:00:00