Hepatitis C virus in Pakistan: a systematic review of prevalence, genotypes and risk factors.

abstract：AIM:To conduct a prospective assessment of anti-hepatitis E virus (HEV) IgG seroprevalence in the Western Cape Province of South Africa in conjunction with evaluating risk factors for exposure. METHODS:Consenting participants attending clinics and wards of Groote Schuur, Red Cross Children's Hospital and their affilia...

journal_title：World journal of gastroenterology

authors： Madden RG,Wallace S,Sonderup M,Korsman S,Chivese T,Gavine B,Edem A,Govender R,English N,Kaiyamo C,Lutchman O,van der Eijk AA,Pas SD,Webb GW,Palmer J,Goddard E,Wasserman S,Dalton HR,Spearman CW

更新日期：2016-11-28 00:00:00

abstract：AIM:To evaluate the prognosis of type II diabetes mellitus (T2DM) after gastrectomy and related factors in gastric cancer patients. METHODS:403 gastric cancer patients with T2DM were studied, who underwent gastrectomy between May 2003 and September 2009. A review of medical records and telephone interviews was perform...

journal_title：World journal of gastroenterology

authors： Kim JW,Cheong JH,Hyung WJ,Choi SH,Noh SH

更新日期：2012-01-07 00:00:00

abstract：AIM:The prognosis of early gastric carcinoma (EGC) is generally excellent after surgery. The presence or absence of lymph node metastasis in EGC is an important prognostic factor. The survival and recurrence rates of node-negative EGC are much better than those of node-positive EGC. This study examined the factors rela...

journal_title：World journal of gastroenterology

authors： Kim DY,Joo JK,Ryu SY,Kim YJ,Kim SK

更新日期：2004-03-01 00:00:00

abstract：AIM:To clarify the molecular mechanism involved in pathogenesis of colorectal cancer as well as clinical significance of genetic analysis of histological samples. METHODS:A total of 480 blood and tissue specimens were collected in our hospital from January 2011 to October 2012. In the observation group, there were 120...

journal_title：World journal of gastroenterology

authors： Yan ZH,Cui LH,Wang XH,Li C,He X

更新日期：2014-12-28 00:00:00

abstract：:Anti-tumour necrosis factor α (anti-TNFα) therapy is an established treatment in inflammatory bowel disease. However, this treatment is associated with high costs and the possibility of severe adverse events representing a true challenge for patients, clinicians and health care systems. Consequently, a crucial questio...

journal_title：World journal of gastroenterology

authors： Papamichael K,Vermeire S

更新日期：2015-04-28 00:00:00

abstract：AIM:To investigate whether autofluorescence imaging (AFI) endoscopy can distinguish non-erosive reflux disease (NERD) from functional heartburn (FH). METHODS:In this prospective observational trial, 127 patients presenting with typical reflux symptoms for > 6 mo were screened. All the participants underwent endoscopy,...

journal_title：World journal of gastroenterology

authors： Luo X,Guo XX,Wang WF,Peng LH,Yang YS,Uedo N

更新日期：2016-04-14 00:00:00

abstract：AIM:To investigate the gastrin secreting cells (G cells) and the somatostatin secreting cells (D cells) of antral mucosa in rats at the ultrastructural level. METHODS:Revised immunoelectron microscopic technique was used to detect the G cells and D cells in rat antral mucosa through gastrin and somatostatin antibodies...

journal_title：World journal of gastroenterology

authors： Sun FP,Song YG

更新日期：2003-12-01 00:00:00

abstract：AIM:To evaluate if the administration of an enteral diet supplemented with glutamine, arginine and omega-3-fatty acids modulates inflammatory and immune responses after surgery. METHODS:A prospective randomized double-blind, clinical trial was performed. Forty-eight patients with gastrointestinal cancer were randomize...

journal_title：World journal of gastroenterology

authors： Wu GH,Zhang YW,Wu ZH

更新日期：2001-06-01 00:00:00

abstract：AIM:To investigate the roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells. METHODS:Human gastric cancer SGC-7901 cells were treated with VES at 5, 10, 20 mg x L(-1), succinic acid and vitamin E as vehicle control and condition media only as untreated (UT) con...

journal_title：World journal of gastroenterology

authors： Wu K,Li Y,Zhao Y,Shan YJ,Xia W,Yu WP,Zhao L

更新日期：2002-12-01 00:00:00

abstract：AIM:To determine short- and long-term outcomes of endoscopic submucosal dissection (ESD) using the stag beetle (SB) knife, a scissor-shaped device. METHODS:Seventy consecutive patients with 96 early esophageal neoplasms, who underwent ESD using a SB knife at Kure Medical Center and Chugoku Cancer Center, Japan, betwee...

journal_title：World journal of gastroenterology

authors： Kuwai T,Yamaguchi T,Imagawa H,Miura R,Sumida Y,Takasago T,Miyasako Y,Nishimura T,Iio S,Yamaguchi A,Kouno H,Kohno H,Ishaq S

更新日期：2018-04-21 00:00:00

abstract：:Arthrogryposis, renal dysfunction and cholestasis (ARC) syndrome (OMIM 208085) is an autosomal recessive disorder that is caused by mutations in 2 interacting genes VPS33B and VIPAS39. Mutations in VPS33B gene account for most cases of ARC. As low or normal gamma-glutamyl transpeptidase (GGT) activity has been describ...

journal_title：World journal of gastroenterology

authors： Wang JS,Zhao J,Li LT

更新日期：2014-04-28 00:00:00

abstract：AIM:To evaluate the feasibility of quantifying liver choline concentrations in both normal and apoptotic rabbit livers in vivo, using 1H magnetic resonance spectroscopy (1H-MRS). METHODS:1H-MRS was performed in 18 rabbits using a 1.5T GE MR system with an eight-channel head/neck receiving coil. Fifteen rabbits were in...

journal_title：World journal of gastroenterology

authors： Shen ZW,Cao Z,You KZ,Yang ZX,Xiao YY,Cheng XF,Chen YW,Wu RH

更新日期：2012-03-14 00:00:00

abstract：AIM:To look for the evidence of human papilloma virus (HPV) infection in esophageal squamous cell carcinomas (ESCC) and to investigate the potential role and epidemiology of HPV infection in the pathogenesis of esophageal carcinomas in Henan emigrants. METHODS:Papilloma virus(PV) and HPV were determined by Ultrasensiv...

journal_title：World journal of gastroenterology

authors： Yao PF,Li GC,Li J,Xia HS,Yang XL,Huang HY,Fu YG,Wang RQ,Wang XY,Sha JW

更新日期：2006-03-07 00:00:00

abstract：AIM:To investigate the effects of exogenously mutated p27(kipl) (p27) on proliferation and apoptosis of human cholangiocarcinoma cell line, QBC(939)in vivo. METHODS:Adenviral vectors were used to transfect mutated p27 cDNA into human QBC(939)cell line. Expression of p27 was detected by RT-PCR. Western blot. Cell growt...

journal_title：World journal of gastroenterology

authors： Luo J,Chen YJ,Wang WY,Zou SQ

更新日期：2008-09-14 00:00:00

abstract：:We report a rare case of a 68-year-old male with metachronous pancreatic metastasis that was resected 2 years after salvage esophagectomy for local recurrence of esophageal squamous cell carcinoma (ESCC). Two years and 8 mo ago, he had undergone definitive chemoradiotherapy for the lower thoracic ESCC and achieved a c...

journal_title：World journal of gastroenterology

authors： Okamoto H,Hara Y,Chin M,Hagiwara M,Onodera Y,Horii S,Shirahata Y,Kamei T,Hashizume E,Ohuchi N

更新日期：2014-01-14 00:00:00

abstract：AIM:To identify the predictive clinicopathological factors for lymph node metastasis (LNM) in poorly differentiated early gastric cancer (EGC) and to further expand the possibility of using endoscopic mucosal resection (EMR) for the treatment of poorly differentiated EGC. METHODS:Data were collected from 85 poorly-dif...

journal_title：World journal of gastroenterology

authors： Li H,Lu P,Lu Y,Liu CG,Xu HM,Wang SB,Chen JQ

更新日期：2008-07-14 00:00:00

abstract：AIM:To meta-analyse the European abstracts presented between 1997-2004 at the European H pylori Study Group, United European Gastroenterology Week meetings and World Congresses of Gastroenterology. METHODS:The abstracts of randomized/controlled prospective studies were classified into groups based on first-line eradic...

journal_title：World journal of gastroenterology

authors： Buzás GM,Józan J

更新日期：2006-09-07 00:00:00

abstract：AIM:To identify whether chitinase 3-like 1 (CHI3L1) serves as a suitable biomarker for the prognosis of esophageal squamous cell carcinoma (ESCC) and to analyze this protein's cellular source. METHODS:An ELISA was conducted to detect the concentration of CHI3L1 in the serum of 150 ESCC patients diagnosed between Janua...

journal_title：World journal of gastroenterology

authors： Xing S,Zheng X,Zeng T,Zeng MS,Zhong Q,Cao YS,Pan KL,Wei C,Hou F,Liu WL

更新日期：2017-11-21 00:00:00

abstract：:AIM:To assess the diagnostic values of tumor markers for pancreatic cancer.METHODS:Pancreatic cancer-associated antigen from colonic mucosa (PCAAc), pancreas-specific antigen (PaA), pancreatic oncofetal antigen (POA) and minimolecular pancreatic antigen (mPOA) were detected by double antibodies Sandwich ELISA; CA19-9,...

journal_title：World journal of gastroenterology

authors： Zhao XY,Yu SY,Da SP,Bai L,Guo XZ,Dai XJ,Wang YM

更新日期：1998-04-01 00:00:00

abstract：:During the last decade, inflammation (carditis) and intestinal metaplasia localized to immediately below the human gastro-oesophageal junction have received much attention in relation to the rising incidence of cancer at this site. Since these histological findings are frequently observed even among those who are H py...

journal_title：World journal of gastroenterology

authors： Iijima K,Shimosegawa T

更新日期：2006-09-28 00:00:00

abstract：:E2F family of transcription factors regulates various cellular functions related to cell cycle and apoptosis. Its individual members have traditionally been classified into activators and repressors, based on in vitro studies. However their contribution in human cancer is more complicated and difficult to predict. We ...

journal_title：World journal of gastroenterology

authors： Xanthoulis A,Tiniakos DG

更新日期：2013-06-07 00:00:00

abstract：AIM:To study the relationship between Helicobacter pylori (H. pylori) and gastric carcinoma and its possible pathogenesis by H. pylori. METHODS:DNEL technique and immunohistochemical technique were used to study the state of apoptosis, proliferation and p53 gene expression. A total of 100 gastric mucosal biopsy specim...

journal_title：World journal of gastroenterology

authors： Zhang Z,Yuan Y,Gao H,Dong M,Wang L,Gong YH

更新日期：2001-12-01 00:00:00

abstract：AIM:To investigate microRNA-133a (miR-133a) expression in colorectal cancer (CRC) and its relationship with tumorigenesis and disease prognosis. METHODS:Quantitative real-time polymerase chain reaction was used to measure levels of miR-133a in tumor samples and adjacent non-cancerous tissues from 169 patients undergoi...

journal_title：World journal of gastroenterology

authors： Wang LL,Du LT,Li J,Liu YM,Qu AL,Yang YM,Zhang X,Zheng GX,Wang CX

更新日期：2014-08-28 00:00:00

abstract：AIM:To study the efficacy and factors associated with a sustained virological response (SVR) in chronic hepatitis C (CHC) relapsing patients. METHODS:Out of 1228 CHC patients treated with pegylated interferon (PEG-IFN) and ribavirin (RBV), 165 (13%) had a relapse. Among these, 62 patients were retreated with PEG-IFN-α...

journal_title：World journal of gastroenterology

authors： Stern C,Martinot-Peignoux M,Ripault MP,Boyer N,Castelnau C,Valla D,Marcellin P

更新日期：2012-06-21 00:00:00

abstract：AIM:To explore the inducing effect of human mutant p27 gene on the apoptosis of the human gastric cancer cell line MKN-45 and its associated mechanisms. METHODS:The recombinant adenovirus Ad-p27mt was constructed to infect the human gastric cancer cell line MKN-45. Using flow cytometry, TUNEL assay and DNA fragment an...

journal_title：World journal of gastroenterology

authors： Zhu JS,Wang L,Cheng GQ,Li Q,Zhu ZM,Zhu L

更新日期：2005-12-21 00:00:00

abstract：:Currently approved treatments for hepatitis B virus (HBV) infection include the immunomodulatory agent, IFN-alpha, and nucleos(t)ide analogues. Their efficacy is limited by their side effects, as well as the induction of viral mutations that render them less potent. It is thus necessary to develop drugs that target ad...

journal_title：World journal of gastroenterology

authors： Wu GY,Chen HS

更新日期：2007-02-14 00:00:00

abstract：:The scientific framework concerning estrogen effects on different tissues has expanded enormously during the last decades, when estrogen receptor (ER) subtypes were identified. Estrogens are not only essential for the female reproductive system, but they also control fundamental functions in other tissues including th...

journal_title：World journal of gastroenterology

authors： Alvaro D,Mancino MG,Onori P,Franchitto A,Alpini G,Francis H,Glaser S,Gaudio E

更新日期：2006-06-14 00:00:00

abstract：:Video capsule endoscopy (CE) since its introduction 13 years back, has revolutionized our approach to small intestinal diseases. Obscure gastrointestinal bleed (OGIB) continues to be the most important indication for CE with a high sensitivity, specificity as well as positive and negative predictive values. It is best...

journal_title：World journal of gastroenterology

authors： Goenka MK,Majumder S,Goenka U

更新日期：2014-08-07 00:00:00

abstract：AIM:To investigate the relationship and molecular features of CD74/macrophage migration inhibitory factor (MIF)/Toll-like receptor 4 (TLR4) in gastric cancer. METHODS:CD74, MIF and TLR4 expression in the paraffin-embedded sections of gastric cancer from 120 patients were detected by immunohistochemical staining. Knock...

journal_title：World journal of gastroenterology

authors： Zheng YX,Yang M,Rong TT,Yuan XL,Ma YH,Wang ZH,Shen LS,Cui L

更新日期：2012-05-14 00:00:00

abstract：AIM:To investigate whether composite yogurt with acacia dietary fiber and Bifidobacterium lactis (B. lactis) has additive effects in irritable bowel syndrome (IBS). METHODS:A total of 130 patients were randomly allocated to consume, twice daily for 8 wk, either the composite yogurt or the control product. The composit...

journal_title：World journal of gastroenterology

authors： Min YW,Park SU,Jang YS,Kim YH,Rhee PL,Ko SH,Joo N,Kim SI,Kim CH,Chang DK

更新日期：2012-09-07 00:00:00