A clinical evaluation of serological diagnosis for pancreatic cancer.

abstract：AIM:To investigate whether ANNs and LDA could recognize patients with ABG in a database, containing only clinical and biochemical variables, of a pool of patients with and without ABG, by selecting the most predictive variables and by reducing input data to the minimum. METHODS:Data was collected from 350 consecutive ...

journal_title：World journal of gastroenterology

authors： Lahner E,Grossi E,Intraligi M,Buscema M,Corleto VD,Delle Fave G,Annibale B

更新日期：2005-10-07 00:00:00

abstract：AIM:To quantify the impact of split-dose regimen on endoscopists' compliance with guideline recommendations for timing of repeat colonoscopy in patients with normal colonoscopy or 1-2 small polyps (< 10 mm). METHODS:A retrospective chart review of all endoscopy reports was undertaken in average-risk individuals > 50 y...

journal_title：World journal of gastroenterology

authors： Menees SB,Kim HM,Schoenfeld P

更新日期：2018-02-14 00:00:00

abstract：AIM:To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS:Production of recombinant sH2a and development of a monoclonal antibody and an enzyme-linked immunosorbent assay (ELISA). This assay was used to determine the presence and concentrati...

journal_title：World journal of gastroenterology

authors： Benyair R,Kondratyev M,Veselkin E,Tolchinsky S,Shenkman M,Lurie Y,Lederkremer GZ

更新日期：2011-12-28 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the major causes of morbidity and mortality in patients with chronic liver disease. Transarterial chemoembolization (TACE) can significantly improve the survival rate of patients with HCC and is the first treatment choice for patients who are not suitable for surgical resection...

journal_title：World journal of gastroenterology

authors： Yang K,Zhang XM,Yang L,Xu H,Peng J

更新日期：2016-05-28 00:00:00

abstract：:Coeliac disease (CD) is a complex condition resulting from an interplay between genetic and environmental factors. When diagnosing the condition, serological testing and genotyping are useful in excluding CD, although the gold standard of testing is currently histopathological examination of the small intestine. There...

journal_title：World journal of gastroenterology

authors： Charlesworth RP

更新日期：2020-01-07 00:00:00

abstract：:Pancreatic cystic lesions (PCLs) are increasingly being identified because of the widespread use of high-resolution abdominal imaging. These cysts encompass a spectrum from malignant disease to benign lesions, and therefore, accurate diagnosis is crucial to determine the best management strategy, either surgical resec...

journal_title：World journal of gastroenterology

authors： Alvarez-Sánchez MV,Napoléon B

更新日期：2018-07-14 00:00:00

abstract：AIM:To evaluate the impact of sociodemographic/clinical factors on early virological response (EVR) to peginterferon/ribavirin for chronic hepatitis C (CHC) in clinical practice. METHODS:We conducted a multicenter, cross-sectional, observational study in Hepatology Units of 91 Spanish hospitals. CHC patients treated w...

journal_title：World journal of gastroenterology

authors： García-Samaniego J,Romero M,Granados R,Alemán R,Jorge Juan M,Suárez D,Pérez R,Castellano G,González-Portela C

更新日期：2013-03-28 00:00:00

abstract：AIM:To see the possibility of avoiding routine colostomy in patients presenting with unprepared bowel. METHODS:The cohort is composed of 103 patients, of these, 86 patients presented as emergencies (self-inflected and iatrogenic colon injuries, stab wounds and blast injury of the colon, volvulus sigmoid, obstructing l...

journal_title：World journal of gastroenterology

authors： Asfar SK,Al-Sayer HM,Juma TH

更新日期：2007-06-21 00:00:00

abstract：AIM:To review the cases reported in the literature, examined their clinicopathological features, and evaluated the efficacy of different therapeutic modalities for this rare condition. METHODS:A search of the MEDLINE database revealed 16 cases of pericarditis carcinomatosa (PC) originating from GC reported in the lite...

journal_title：World journal of gastroenterology

authors： Kobayashi M,Okabayashi T,Okamoto K,Namikawa T,Araki K

更新日期：2005-11-28 00:00:00

abstract：AIM:To evaluate the optimal intervention point of a selective cyclooxygenase-2 (COX-2) inhibitor, celecoxib, for inhibiting Helicobacter pylori (H. pylori)-associated gastric carcinogenesis in Mongolian gerbils (MGs). METHODS:One hundred and twelve MGs were divided into six groups (A-F). One hundred gerbils were inocu...

journal_title：World journal of gastroenterology

authors： Kuo CH,Hu HM,Tsai PY,Wu IC,Yang SF,Chang LL,Wang JY,Jan CM,Wang WM,Wu DC

更新日期：2009-10-21 00:00:00

abstract：AIM:To investigate the safety and feasibility of needlescopic grasper-assisted single-incision laparoscopic common bile duct exploration (nSIL-CBDE) by comparing the surgical outcomes of this technique with those of conventional laparoscopic CBDE (CL-CBDE). METHODS:We retrospectively analyzed the clinical data of pati...

journal_title：World journal of gastroenterology

authors： Kim SJ,Kim KH,An CH,Kim JS

更新日期：2015-12-07 00:00:00

abstract：BACKGROUND:Intrahepatic cholangiocarcinoma (ICC) is a heterogeneous hepatobiliary cancer with limited treatment options. A number of studies have illuminated the relationship between inflammation-based prognostic scores and outcomes in patients with ICC. However, the use of reliable and personalized prognostic algorith...

journal_title：World journal of gastroenterology

authors： Wang JJ,Li H,Li JX,Xu L,Wu H,Zeng Y

更新日期：2020-04-07 00:00:00

abstract：AIM:To determine the possible existence of a hepato-cardiovascular response and its regulatory mechanism in normal rats. METHODS:Systemic hemodynamic changes following intraportal injection of latex microspheres were studied in two modified rat models of hepatic circulation, in which the extrahepatic splanchnic circul...

journal_title：World journal of gastroenterology

authors： Li XN,Benjamin IS,Alexander B

更新日期：2005-02-07 00:00:00

abstract：AIM:To investigate whether butyrate or glutamine enemas could diminish inflammation in experimental diversion colitis. METHODS:Wistar specific pathogen-free rats were submitted to a Hartmann's end colostomy and treated with enemas containing glutamine, butyrate, or saline. Enemas were administered twice a week in the ...

journal_title：World journal of gastroenterology

authors： Pacheco RG,Esposito CC,Müller LC,Castelo-Branco MT,Quintella LP,Chagas VL,de Souza HS,Schanaider A

更新日期：2012-08-28 00:00:00

abstract：AIM:To investigate the efficacy of neoadjuvant chemoradiotherapy (NACRT) for resectability of locally advanced gastric cancer (LAGC). METHODS:Between November 2007 and January 2014, 29 patients with LAGC (clinically T3 with distal esophagus invasion/T4 or bulky regional node metastasis) that were treated with NACRT fo...

journal_title：World journal of gastroenterology

authors： Kim MS,Lim JS,Hyung WJ,Lee YC,Rha SY,Keum KC,Koom WS

更新日期：2015-03-07 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is a highly invasive tumor that metastasizes hematogenously and lymphogenously to distant site. Frequent sites are lung, regional lymph node, bone, and adrenal gland. But metastasis to the gastrointestinal (GI) tract is rare, and most common site is stomach. Metastasis to the small intes...

journal_title：World journal of gastroenterology

authors： Kim HS,Shin JW,Kim GY,Kim YM,Cha HJ,Jeong YK,Jeong ID,Bang SJ,Kim DH,Park NH

更新日期：2006-03-28 00:00:00

abstract：AIM:To assess the viability of orthotopic and heterotopic patient-derived pancreatic cancer xenografts implanted into nude mice. METHODS:This study presents a prospective experimental analytical follow-up of the development of tumours in mice upon implantation of human pancreatic adenocarcinoma samples. Specimens were...

journal_title：World journal of gastroenterology

authors： Rubio-Manzanares Dorado M,Marín Gómez LM,Aparicio Sánchez D,Pereira Arenas S,Praena-Fernández JM,Borrero Martín JJ,Farfán López F,Gómez Bravo MÁ,Muntané Relat J,Padillo Ruiz J

更新日期：2018-02-21 00:00:00

abstract：AIM:To establish an ideal implantable rat liver tumor model for interventional therapy study and examine its angiographic signs and MRI, CT features before and after embolization. METHODS:Forty male Wistar rats were implanted with Walker-256 tumor in the left lateral lobe of liver. Digital subtraction angiography (DSA...

journal_title：World journal of gastroenterology

authors： Li X,Zheng CS,Feng GS,Zhuo CK,Zhao JG,Liu X

更新日期：2002-12-01 00:00:00

abstract：AIM:To investigate a potential role of S100A4 in esophagus squamous cell carcinoma metastasis (ESCCs). METHODS:Expression of S100A4 and E-cadherin were analyzed in frozen sections from ESCCs (metastasis, n = 28; non-metastasis, n = 20) by reverse transcription-polymerase chain reaction, quantitative polymerase chain r...

journal_title：World journal of gastroenterology

authors： Chen D,Zheng XF,Yang ZY,Liu DX,Zhang GY,Jiao XL,Zhao H

更新日期：2012-03-07 00:00:00

abstract：:Pancreatic carcinomas with acinar differentiation are rare, accounting for 1%-2% of adult pancreatic tumors; they include pancreatic acinar cell carcinoma (PACC), pancreatoblastoma, and carcinomas of mixed differentiation. Patients with PACC have a prognosis better than pancreatic ductal adenocarcinomas but worse than...

journal_title：World journal of gastroenterology

authors： Al-Hader A,Al-Rohil RN,Han H,Von Hoff D

更新日期：2017-12-07 00:00:00

abstract：AIM:To construct and highly express an epitope of hepatitis C virus (HCV) in a foreign epitope presenting vector based on an insect virus, and to study the antigenicity of the epitope. METHODS:The HCV epitope sequence (amino acid residues 315 to 328: EGHRMAWDMMMNWS) of the E1 region was constructed at different positi...

journal_title：World journal of gastroenterology

authors： Peng M,Dai CB,Chen YD

更新日期：2005-06-14 00:00:00

abstract：AIM:To investigate the role of nuclear division cycle (NDC)80 in human hepatocellular carcinogenesis. METHODS:NDC80 gene expression was analyzed by real-time reverse transcription polymerase chain reaction in 47 paired hepatocellular carcinoma (HCC) and adjacent tissues. The HCC cell line SMMC-7721 was transfected wit...

journal_title：World journal of gastroenterology

authors： Ju LL,Chen L,Li JH,Wang YF,Lu RJ,Bian ZL,Shao JG

更新日期：2017-05-28 00:00:00

abstract：:The goal of therapy in chronic hepatitis C virus (HCV) infection is sustained virological response (SVR) which reflects HCV eradication. Treatment against HCV has dramatically improved with the recent availability of direct-acting antivirals (DAAs) including sofosbuvir, simeprevir, daclatasvir, ledipasvir/sofosbuvir, ...

journal_title：World journal of gastroenterology

authors： Cholongitas E,Pipili C,Papatheodoridis G

更新日期：2015-08-28 00:00:00

abstract：:Alcoholic patients have a high incidence of hepatitis C virus (HCV) infection. Alcohol consumption enhances the severity of the HCV disease course and worsens the outcome of chronic hepatitis C. The accumulation of virally infected cells in the liver is related to the HCV-induced inability of the immune system to reco...

journal_title：World journal of gastroenterology

authors： Osna NA

更新日期：2009-03-14 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is the commonest chronic liver disease in high-income countries and is associated with increased morbidity and mortality. Macrophages appear to play an important role in the development and progression of hepatic fibrosis in patients with NAFLD. Accordingly, modulation of macro...

journal_title：World journal of gastroenterology

authors： Neokosmidis G,Tziomalos K

更新日期：2018-12-28 00:00:00

abstract：AIM:To detect distribution and relative frequency of endocrine cells in gastrointestinal tract of flower fish (Pseudophoxinus antalyae). METHODS:The intestinal tract of flower fish was divided into four portions from proximal to distal; the enlarged area after oesophagus and anterior, middle and posterior intestine. I...

journal_title：World journal of gastroenterology

authors： Cinar K,Senol N,Ozen MR

更新日期：2006-11-14 00:00:00

abstract：AIM:To objectively evaluate the effect of TJ-68 on colonic spasms during colonoscopy. METHODS:One hundred and one patients subjected to screening colonoscopy were randomly assigned to two groups: TJ-68 in 51 subjects and saline as the control in 50. The endoscope was inserted into the sigmoid colon, then a spastic reg...

journal_title：World journal of gastroenterology

authors： Ai M,Yamaguchi T,Odaka T,Mitsuhashi K,Shishido T,Yan J,Seza A,Saisho H

更新日期：2006-02-07 00:00:00

abstract：AIM:To investigate the diagnostic significance of transient elastography (TE) in a daily routine clinical setting in comparison to clinical signs, laboratory parameters and ultrasound. METHODS:TE, ultrasound, laboratory parameters and cutaneous liver signs were assessed in 291 consecutive patients with chronic liver d...

journal_title：World journal of gastroenterology

authors： Göbel T,Schadewaldt-Tümmers J,Greiner L,Poremba C,Häussinger D,Erhardt A

更新日期：2015-01-21 00:00:00

abstract：:In 2004, an association of genetic variation in the discs large homolog 5 (DLG5) gene with inflammatory bowel disease (IBD) was described in two large European study samples. The initial report of DLG5 as a novel IBD susceptibility gene sparked a multitude of studies investigating its effect on CD and IBD, respectivel...

journal_title：World journal of gastroenterology

authors： Friedrichs F,Stoll M

更新日期：2006-06-21 00:00:00

abstract：AIM:To assess the risk of relapse in ulcerative colitis (UC) patients in clinical remission using mucosal status and fecal immunochemical test (FIT) results. METHODS:The clinical outcomes of 194 UC patients in clinical remission who underwent colonoscopy were based on evaluations of Mayo endoscopic subscores (MESs) an...

journal_title：World journal of gastroenterology

authors： Nakarai A,Kato J,Hiraoka S,Takashima S,Takei D,Inokuchi T,Sugihara Y,Takahara M,Harada K,Okada H

更新日期：2016-06-07 00:00:00