Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis.

abstract：AIM:To investigate whether the degree of rectal distension could define the rectum functions as a conduit or reservoir. METHODS:Response of the rectal and anal pressure to 2 types of rectal balloon distension, rapid voluminous and slow gradual distention, was recorded in 21 healthy volunteers (12 men, 9 women, age 41....

journal_title：World journal of gastroenterology

authors： Shafik A,Mostafa RM,Shafik I,Ei-Sibai O,Shafik AA

更新日期：2006-07-28 00:00:00

abstract：AIM:To investigate the therapeutic effects of mesenchymal stem cells (MSCs) transplanted intraperitoneally and intravenously in a murine model of colitis. METHODS:MSCs were isolated from C57BL/6 mouse adipose tissue. MSC cultures were analyzed according to morphology, cellular differentiation potential, and surface mo...

journal_title：World journal of gastroenterology

authors： Gonçalves Fda C,Schneider N,Pinto FO,Meyer FS,Visioli F,Pfaffenseller B,Lopez PL,Passos EP,Cirne-Lima EO,Meurer L,Paz AH

更新日期：2014-12-28 00:00:00

abstract：AIM:To investigate the relationship between urinary peptide changes and Helicobacter pylori (H. pylori) infection using urinary peptidome profiling. METHODS:The study was performed in volunteers (n=137) who gave informed consent. Urinary peptides were enriched by magnetic beads based weak cation exchange chromatograph...

journal_title：World journal of gastroenterology

authors： Xiao D,Meng FL,He LH,Gu YX,Zhang JZ

更新日期：2011-02-07 00:00:00

abstract：:Pegylated interferon (IFN) α-2a or 2b in combination with ribavirin for children aged 3 years and older is the standard treatment for paediatric chronic hepatitis C. This treatment regimen was developed firstly in adults. In recent years, a number of direct-acting antiviral agents (DAAs) are under development for trea...

journal_title：World journal of gastroenterology

authors： Serranti D,Indolfi G,Resti M

更新日期：2014-11-21 00:00:00

abstract：AIM:To investigate the diagnostic significance of transient elastography (TE) in a daily routine clinical setting in comparison to clinical signs, laboratory parameters and ultrasound. METHODS:TE, ultrasound, laboratory parameters and cutaneous liver signs were assessed in 291 consecutive patients with chronic liver d...

journal_title：World journal of gastroenterology

authors： Göbel T,Schadewaldt-Tümmers J,Greiner L,Poremba C,Häussinger D,Erhardt A

更新日期：2015-01-21 00:00:00

abstract：AIM:To hypothesize that beta-7 integrin affects cellular migration of both, lymphocytes and enterocytes. METHODS:The nucleoside analog BrdU was ip injected in beta-7-deficient mice (C57BL/6-Itgb(tmlcgn)/J) of male gender and age-matched male C57BL/J J mice (wild type) 4, 20, or 40 h before analysis. The total small in...

journal_title：World journal of gastroenterology

authors： Kaemmerer E,Kuhn P,Schneider U,Clahsen T,Jeon MK,Klaus C,Andruszkow J,Härer M,Ernst S,Schippers A,Wagner N,Gassler N

更新日期：2015-02-14 00:00:00

abstract：AIM:To examine the protective effect of green tea extract (GT) on hepatic fibrosis in vitro and in vivo in dimethylnitrosamine (DMN)-induced rats. METHODS:HSC-T6, a rat hepatic stellate cell line, was used as an in vitro assay system. Cell proliferation, collagen content, and type 1 collagen expression were examined i...

journal_title：World journal of gastroenterology

authors： Kim HK,Yang TH,Cho HY

更新日期：2009-11-07 00:00:00

abstract：:Hepatitis C is recognized as a major threat to global public health. The current treatment of patients with chronic hepatitis C is the addition of ribavirin to interferon-based therapy which has limited efficacy, poor tolerability, and significant expense. New treatment options that are more potent and less toxic are ...

journal_title：World journal of gastroenterology

authors： Khattab MA

更新日期：2009-07-28 00:00:00

abstract：AIM:To carry out a hospital-based case-control study to investigate risk factors for intrahepatic cholangiocarcinoma (ICC) in China. METHODS:A total of 312 ICC cases and 438 matched controls were included in the study. The presence of diabetes mellitus, hypertension, hepatolithiasis, primary sclerosing cholangitis, li...

journal_title：World journal of gastroenterology

authors： Zhou YM,Yin ZF,Yang JM,Li B,Shao WY,Xu F,Wang YL,Li DQ

更新日期：2008-01-28 00:00:00

abstract：:Crohn's disease is a chronic inflammatory granulomatous process that usually involves different sites in the intestinal tract. Genetic and environmental factors are thought to play a role in its etiology and pathogenesis. The disorder has a heterogeneous clinical expression and data from tertiary care settings have do...

journal_title：World journal of gastroenterology

authors： Freeman HJ

更新日期：2009-03-21 00:00:00

abstract：INTRODUCTION:This paper provides a review of the practice of liver transplantation with the main emphasis on UK practice and indications for transplantation. REFERRAL AND ASSESSMENT:This section reviews the process of referral and assessment of patients with liver disease with reference to UK practice. DONOR ORGANS:T...

journal_title：World journal of gastroenterology

authors： Bramhall SR,Minford E,Gunson B,Buckels JA

更新日期：2001-10-01 00:00:00

abstract：:Sorafenib has been considered the standard of care for patients with advanced unresectable hepatocellular carcinoma (HCC) since 2007 and numerous studies have investigated the role of markers involved in the angiogenesis process at both the expression and genetic level and clinical aspect. What results have ten years ...

journal_title：World journal of gastroenterology

authors： Marisi G,Cucchetti A,Ulivi P,Canale M,Cabibbo G,Solaini L,Foschi FG,De Matteis S,Ercolani G,Valgiusti M,Frassineti GL,Scartozzi M,Casadei Gardini A

更新日期：2018-09-28 00:00:00

abstract：:AIM:To compare the features of gastroesophageal reflux disease between elderly and younger patients.METHODS:Twenty-four hour pH-monitoring and endoscopy were performed for the 66 elderly patients with typical gastroesophageal reflux symptoms, and the results were compared with 112 symptomatic younger patients.RESULTS:...

journal_title：World journal of gastroenterology

authors： Huang X,Zhu HM,Deng CZ,Porro GB,Sangaletti O,Pace F

更新日期：1999-10-01 00:00:00

abstract：AIM:To improve anti-inflammatory activity while reducing drug doses, we developed a nanoformulation carrying dexamethasone and butyrate. METHODS:Dexamethasone cholesteryl butyrate-solid lipid nanoparticles (DxCb-SLN) were obtained with the warm microemulsion method. The anti-inflammatory activity of this novel nanofor...

journal_title：World journal of gastroenterology

authors： Dianzani C,Foglietta F,Ferrara B,Rosa AC,Muntoni E,Gasco P,Della Pepa C,Canaparo R,Serpe L

更新日期：2017-06-21 00:00:00

abstract：:An inefficient cellular immune response likely leads to chronic hepatitis C virus (HCV) infection. Resolution of chronic HCV infection in the absence of treatment is a rare occurrence. We report the case of a 39-year old white male with a 17-year history of chronic HCV infection, who eradicated HCV following a serious...

journal_title：World journal of gastroenterology

authors： Byrnes V,Chopra S,Koziel MJ

更新日期：2007-08-21 00:00:00

abstract：AIM:To explore molecular mechanism of nicotinamide adenine dinucleotide (NADH) antagonization against X-ray induced L02 cells damage. METHODS:L02 liver cells were cultured in RPMI 1640, exposed to X-ray irradiation and continued to culture in the presence or absence of NADH. Cellular viability was analyzed by routine ...

journal_title：World journal of gastroenterology

authors： Liu FQ,Zhang JR

更新日期：2003-08-01 00:00:00

abstract：AIM:To determine the incidence of brain metastasis in a contemporary group of patients with carcinoma of the esophagus. METHODS:Retrospective analysis of 53 patients with esophageal carcinoma who received radiotherapy as a component of treatment between 1998 and 2007, including patient and tumor characteristics, and s...

journal_title：World journal of gastroenterology

authors： Smith RS,Miller RC

更新日期：2011-05-21 00:00:00

abstract：:Investigation of the possible role of Campylobacter concisus (C. concisus) in inflammatory bowel disease (IBD) is an emerging research area. Despite the association found between C. concisus and IBD, it has been difficult to explain how C. concisus, a bacterium that is commonly present in the human oral cavity, may co...

journal_title：World journal of gastroenterology

authors： Zhang L,Lee H,Grimm MC,Riordan SM,Day AS,Lemberg DA

更新日期：2014-02-07 00:00:00

abstract：AIM:To evaluate the clinical outcomes and safety of anterior- and conventional-approach hepatectomy for patients with large liver tumors. METHODS:PubMed, EMBASE, Google Scholar and the Cochrane Library databases were searched for randomized controlled trials (RCTs) and controlled clinical trials comparing anterior-app...

journal_title：World journal of gastroenterology

authors： Li L,Wang HQ,Wang Q,Yang J,Yang JY

更新日期：2014-12-07 00:00:00

abstract：AIM:To identify the prognostic value of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections in patients with intrahepatic cholangiocarcinoma. METHODS:A search was performed for relevant publications in PubMed, EMBASE and Web of Science databases. The pooled effects were calculated from the available informa...

journal_title：World journal of gastroenterology

authors： Wang Z,Sheng YY,Dong QZ,Qin LX

更新日期：2016-03-14 00:00:00

abstract：:A 70-year-old woman was found to have 2 cystic lesions in the head of the pancreas on abdominal ultrasonography during a routine medical examination. Endoscopic ultrasonography (EUS) and magnetic resonance cholangiopancreatography showed multilocular cysts in the head of the pancreas without dilation of the main pancr...

journal_title：World journal of gastroenterology

authors： Urata T,Naito Y,Izumi Y,Takekuma Y,Yokomizo H,Nagamine M,Fukuda S,Notohara K,Hifumi M

更新日期：2013-12-21 00:00:00

abstract：:High-quality data remains scarce in terms of optimal management strategies in the elderly inflammatory bowel disease (IBD) population. Indeed, available trials have been mostly retrospective, of small sample size, likely owing to under-representation of such a population in the major randomized controlled trials. Howe...

journal_title：World journal of gastroenterology

authors： LeBlanc JF,Wiseman D,Lakatos PL,Bessissow T

更新日期：2019-08-14 00:00:00

abstract：:A 66-year-old female presented with the main complaint of defecation trouble and abdominal distention. With diagnosis of rectal cancer, cSS, cN0, cH0, cP0, cM0 cStage II, Hartmann's operation with D3 lymph node dissection was performed and a para-aortic lymph node and a disseminated node near the primary tumor were re...

journal_title：World journal of gastroenterology

authors： Takeshita N,Fukunaga T,Kimura M,Sugamoto Y,Tasaki K,Hoshino I,Ota T,Maruyama T,Tamachi T,Hosokawa T,Asai Y,Matsubara H

更新日期：2015-11-28 00:00:00

abstract：AIM:To evaluate the impact of therapeutic education on adherence to antiviral treatment and sustained virological response (SVR) in a real-life setting in genotype 2/3 hepatitis C, as there are few adherence data in genotype 2/3 infection, even from randomized trials. METHODS:This prospective survey included genotype ...

journal_title：World journal of gastroenterology

authors： Cacoub P,Ouzan D,Melin P,Lang JP,Rotily M,Fontanges T,Varastet M,Chousterman M,Marcellin P

更新日期：2008-10-28 00:00:00

abstract：AIM:To evaluate the efficacy of stents in treating patients with anastomotic site obstructions due to cancer recurrence following colorectal surgery. METHODS:The medical records of patients who underwent endoscopic self-expanding metal stents (SEMS) insertion for colorectal obstructions between February 2004 and Janua...

journal_title：World journal of gastroenterology

authors： Kim JH,Lee JJ,Cho JH,Kim KO,Chung JW,Kim YJ,Kwon KA,Park DK,Kim JH

更新日期：2014-10-14 00:00:00

abstract：AIM:To evaluate the diagnostic values of serum autoantibodies against matrix metalloproteinase-7 (MMP-7) in patients with esophageal squamous cell carcinoma (ESCC). METHODS:The MMP-7 cDNA was cloned from ESCC tissues, and MMP-7 was expressed and purified from a prokaryotic system. MMP-7 autoantibodies were then measur...

journal_title：World journal of gastroenterology

authors： Zhou JH,Zhang B,Kernstine KH,Zhong L

更新日期：2011-03-14 00:00:00

abstract：:A 55-year old male patient was diagnosed with strongy-loides hyper-infection with stool analysis and intestinal biopsy shortly after his chemotherapy for myeloma. He was commenced on albendazole anthelmintic therapy. After initiation of the treatment he suffered life-threatening gastrointestinal (GI) bleeding. Repeate...

journal_title：World journal of gastroenterology

authors： Csermely L,Jaafar H,Kristensen J,Castella A,Gorka W,Chebli AA,Trab F,Alizadeh H,Hunyady B

更新日期：2006-10-21 00:00:00

abstract：AIM:To examine the prevalence and prognostic significance of C-kit gene mutation and analysis the correlation of C-kit gene mutation and the clinicalpathologic parameters of GISTs. METHODS:Eighty-two GISTs were studied for the mutation of C-kit gene by PCR-SSCP, DNA sequence. Statistical comparison were used to analys...

journal_title：World journal of gastroenterology

authors： Liu XH,Bai CG,Xie Q,Feng F,Xu ZY,Ma DL

更新日期：2005-07-07 00:00:00

abstract：:Percutaneous ablation using thermal or chemical methods has been widely used in the treatment of hepatocellular carcinoma (HCC). Nowadays, contrast-enhanced imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and contrast-enhanced ultrasound (CEUS) are widely used to evaluate local t...

journal_title：World journal of gastroenterology

authors： Liu LN,Xu HX,Zhang YF,Xu JM

更新日期：2013-02-14 00:00:00

abstract：:Hepatoblastoma is the most common primary hepatic tumor of children. However, only a very few cases have been reported in adults. Most studies support treatment with chemotherapy followed by surgical resection. We present the first reported case of adult hepatoblastoma in Taiwan. A 52-year-old female suffered from sud...

journal_title：World journal of gastroenterology

authors： Ke HY,Chen JH,Jen YM,Yu JC,Hsieh CB,Chen CJ,Liu YC,Chen TW,Chan DC

更新日期：2005-10-21 00:00:00