New horizons in the endoscopic ultrasonography-based diagnosis of pancreatic cystic lesions.

Abstract:

:Pancreatic cystic lesions (PCLs) are increasingly being identified because of the widespread use of high-resolution abdominal imaging. These cysts encompass a spectrum from malignant disease to benign lesions, and therefore, accurate diagnosis is crucial to determine the best management strategy, either surgical resection or surveillance. However, the current standard of diagnosis is not accurate enough due to limitations of imaging and tissue sampling techniques, which entail the risk of unnecessary burdensome surgery for benign lesions or missed opportunities of prophylactic surgery for potentially malignant PCLs. In the last decade, endoscopic innovations based on endoscopic ultrasonography (EUS) imaging have emerged, aiming to overcome the present limitations. These new EUS-based technologies are contrast harmonic EUS, needle-based confocal endomicroscopy, through-the-needle cystoscopy and through-the needle intracystic biopsy. Here, we present a comprehensive and critical review of these emerging endoscopic tools for the diagnosis of PCLs, with a special emphasis on feasibility, safety and diagnostic performance.

journal_name

World J Gastroenterol

authors

Alvarez-Sánchez MV,Napoléon B

doi

10.3748/wjg.v24.i26.2853

subject

Has Abstract

pub_date

2018-07-14 00:00:00

pages

2853-2866

issue

26

eissn

1007-9327

issn

2219-2840

journal_volume

24

pub_type

杂志文章,评审
  • Prevalence of diverticulosis in recurrent Clostridium difficile infection.

    abstract:AIM:To re-evaluate the theory that colonic diverticulosis is associated with relapse of Clostridium difficile associated disease (CDAD) in light of data suggesting increasing rates of CDAD infection and relapse. METHODS:Charts were reviewed for patients with recurrent CDAD who had also had a prior colonoscopy or flexi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i3.345

    authors: Lipp MJ,Pagovich OE,Rabin D,Min AD,Bernstein BB

    更新日期:2010-01-21 00:00:00

  • A case of intrahepatic clear cell cholangiocarcinoma.

    abstract::Intrahepatic clear cell cholangiocarcinoma is very rare - only 8 cases have been reported. A 56-year-old Japanese man with chronic hepatitis B infection was diagnosed with a 2.2 cm hepatocellular carcinoma on imaging, and hepatic segmentectomy was performed. Histopathologically, the tumor cells had copious clear cytop...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i20.2571

    authors: Toriyama E,Nanashima A,Hayashi H,Abe K,Kinoshita N,Yuge S,Nagayasu T,Uetani M,Hayashi T

    更新日期:2010-05-28 00:00:00

  • Demethylation of tumor necrosis factor-α converting enzyme promoter associated with high hepatitis B e antigen level in chronic hepatitis B.

    abstract:AIM:To evaluate tumor necrosis factor-α converting enzyme (TACE) methylation status in patients with chronic hepatitis B (CHB). METHODS:Eighty patients with hepatitis B e antigen (HBeAg)-positive CHB, 80 with HBeAg-negative CHB, and 40 healthy controls (HCs) were randomly enrolled in this study. Genomic DNA was extrac...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i27.8382

    authors: Wang ZL,Gao S,Li XY,Sun FK,Li F,Fan YC,Wang K

    更新日期:2015-07-21 00:00:00

  • P53 immunohistochemical scoring: an independent prognostic marker for patients after hepatocellular carcinoma resection.

    abstract:AIM:To confirm if p53 mutation could be a routine predictive marker for the prognosis of hepatocellular carcinoma (HCC) patients. METHODS:Two hundreds and forty-four formalin-fixed paraffin-embedded tumor samples of the patients with HCC receiving liver resection were detected for nuclear accumulation of p53. The perc...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i3.459

    authors: Qin LX,Tang ZY,Ma ZC,Wu ZQ,Zhou XD,Ye QH,Ji Y,Huang LW,Jia HL,Sun HC,Wang L

    更新日期:2002-06-01 00:00:00

  • Effect of ginger on gastric motility and symptoms of functional dyspepsia.

    abstract:AIM:To evaluate the effects of ginger on gastric motility and emptying, abdominal symptoms, and hormones that influence motility in dyspepsia. METHODS:Eleven patients with functional dyspepsia were studied twice in a randomized double-blind manner. After an 8-h fast, the patients ingested three capsules that contained...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v17.i1.105

    authors: Hu ML,Rayner CK,Wu KL,Chuah SK,Tai WC,Chou YP,Chiu YC,Chiu KW,Hu TH

    更新日期:2011-01-07 00:00:00

  • Body mass index is associated with age-at-onset of HCV-infected hepatocellular carcinoma patients.

    abstract:AIM:To identify factors associated with the age at onset of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). METHODS:Five hundred and fifty-six consecutive patients positive for HCV antibody and treatment-naïve HCC diagnosed between 1995 and 2004 were analyzed. Patients were classified into three groups...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i7.914

    authors: Akiyama T,Mizuta T,Kawazoe S,Eguchi Y,Kawaguchi Y,Takahashi H,Ozaki I,Fujimoto K

    更新日期:2011-02-21 00:00:00

  • Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer.

    abstract:AIM:To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer. METHODS:One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study. The serum concentrations of MMP-1 and TIMP-1 in these patients a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i16.2109

    authors: Kemik O,Kemik AS,Sümer A,Dulger AC,Adas M,Begenik H,Hasirci I,Yilmaz O,Purisa S,Kisli E,Tuzun S,Kotan C

    更新日期:2011-04-28 00:00:00

  • Positron emission tomography/computer tomography in guidance of extrahepatic hepatocellular carcinoma metastasis management.

    abstract::Hepatocellular carcinoma (HCC) is one of the most common primary cancers in the world. Surgery is the gold standard for treatment of patients with HCC. Recurrence and metastasis are the major obstacles to further improve the prognosis of HCC. Most recurrences are intrahepatic. However, 30% of the recurrences are extra...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i40.5413

    authors: Sun L,Guan YS,Pan WM,Chen GB,Luo ZM,Wu H

    更新日期:2007-10-28 00:00:00

  • Endoscopic treatment of Barrett's esophagus: From metaplasia to intramucosal carcinoma.

    abstract::The annual incidence of adenocarcinoma arising from Barrett's esophagus (BE) is approximately 0.5%. Through a process of gradual transformation from low-grade dysplasia to high-grade dysplasia (HGD), adenocarcinoma can develop in the setting of BE. The clinical importance of appropriate identification and treatment of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v16.i30.3780

    authors: Chennat J,Waxman I

    更新日期:2010-08-14 00:00:00

  • Molecular evolution of hepatitis A virus in a human diploid cell line.

    abstract:AIM:To investigate the hotspots, direction, and the time course of evolution of hepatitis A virus in the process of consecutive cell culture passage in human KMB17 diploid cells. METHODS:Wild type hepatitis A virus H2w was serially propagated in KMB17 cells until passage 30, and the full-length genomes of H2w and its ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i34.4630

    authors: Tang CH,Mao JS,Chai SA,Chen Y,Zhuang FC

    更新日期:2007-09-14 00:00:00

  • S100A4 silencing blocks invasive ability of esophageal squamous cell carcinoma cells.

    abstract:AIM:To investigate a potential role of S100A4 in esophagus squamous cell carcinoma metastasis (ESCCs). METHODS:Expression of S100A4 and E-cadherin were analyzed in frozen sections from ESCCs (metastasis, n = 28; non-metastasis, n = 20) by reverse transcription-polymerase chain reaction, quantitative polymerase chain r...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i9.915

    authors: Chen D,Zheng XF,Yang ZY,Liu DX,Zhang GY,Jiao XL,Zhao H

    更新日期:2012-03-07 00:00:00

  • Overexpression of p28/gankyrin in human hepatocellular carcinoma and its clinical significance.

    abstract:AIM:To investigate the expression of p28/gankyrin gene and its role in the carcinogenetic process of human hepatocellular carcinoma (HCC). METHODS:64 specimens of HCC and para-carcinoma tissues, 22 specimens of non-tumor liver tissues (7 normal, 15 cirrhosis), 10 specimens of normal human tissues and 5 hepatoma cell l...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i4.638

    authors: Fu XY,Wang HY,Tan L,Liu SQ,Cao HF,Wu MC

    更新日期:2002-08-01 00:00:00

  • Risk factors for intrahepatic cholangiocarcinoma: a case-control study in China.

    abstract:AIM:To carry out a hospital-based case-control study to investigate risk factors for intrahepatic cholangiocarcinoma (ICC) in China. METHODS:A total of 312 ICC cases and 438 matched controls were included in the study. The presence of diabetes mellitus, hypertension, hepatolithiasis, primary sclerosing cholangitis, li...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.632

    authors: Zhou YM,Yin ZF,Yang JM,Li B,Shao WY,Xu F,Wang YL,Li DQ

    更新日期:2008-01-28 00:00:00

  • Incidence of hepatocellular carcinoma in patients with chronic liver disease due to hepatitis B or C and coinfected with the human immunodeficiency virus: A retrospective cohort study.

    abstract:AIM:To assess the incidence of hepatocellular carcinoma (HCC) in chronic liver disease due to hepatitis B virus (HBV) or hepatitis C virus (HCV) coinfected with human immunodeficiency virus (HIV). METHODS:A retrospective cohort study was performed, including patients with chronic liver disease due to HBV or HCV, with ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i5.613

    authors: Marcon PDS,Tovo CV,Kliemann DA,Fisch P,de Mattos AA

    更新日期:2018-02-07 00:00:00

  • Quantification of choline concentration following liver cell apoptosis using 1H magnetic resonance spectroscopy.

    abstract:AIM:To evaluate the feasibility of quantifying liver choline concentrations in both normal and apoptotic rabbit livers in vivo, using 1H magnetic resonance spectroscopy (1H-MRS). METHODS:1H-MRS was performed in 18 rabbits using a 1.5T GE MR system with an eight-channel head/neck receiving coil. Fifteen rabbits were in...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v18.i10.1130

    authors: Shen ZW,Cao Z,You KZ,Yang ZX,Xiao YY,Cheng XF,Chen YW,Wu RH

    更新日期:2012-03-14 00:00:00

  • alpha,beta-amyrin, a natural triterpenoid ameliorates L-arginine-induced acute pancreatitis in rats.

    abstract:AIM:To study the beneficial effects of triterpene alpha,beta-amyrin and the underlying mechanisms in an experimental pancreatitis model. METHODS:Acute pancreatitis was induced in five groups of rats (n = 8) by L-arginine (2 x 2.5 g/kg, intraperitoneal, 1 h apart) and 1 h later, they received a single oral dose of alph...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i34.4272

    authors: Melo CM,Carvalho KM,Neves JC,Morais TC,Rao VS,Santos FA,Brito GA,Chaves MH

    更新日期:2010-09-14 00:00:00

  • Therapeutic plasma exchange in patients with hyperlipidemic pancreatitis.

    abstract:AIM:To clarify the effectiveness of plasma exchange by comparing the mortality and morbidity before and after the intervention of plasma exchange. METHODS:Plasma exchange has been available as an optional therapy for hyperlipidemic pancreatitis since August 1999 in our hospital. The patients were assorted into 2 group...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v10.i15.2272

    authors: Chen JH,Yeh JH,Lai HW,Liao CS

    更新日期:2004-08-01 00:00:00

  • Colorectal and interval cancers of the Colorectal Cancer Screening Program in the Basque Country (Spain).

    abstract:AIM:To assess proportions, related conditions and survival of interval cancer (IC). METHODS:The programme has a linkage with different clinical databases and cancer registers to allow suitable evaluation. This evaluation involves the detection of ICs after a negative faecal inmunochemical test (FIT), interval cancer F...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v23.i15.2731

    authors: Portillo I,Arana-Arri E,Idigoras I,Bilbao I,Martínez-Indart L,Bujanda L,Gutierrez-Ibarluzea I

    更新日期:2017-04-21 00:00:00

  • Differences in characteristics of colorectal neoplasm between young and elderly Thais.

    abstract:AIM:To analyze the differences of clinical characteristics of colorectal neoplasm including polyps between the elderly and young Thai patients. METHODS:Colonoscopy database from December 2000 to October 2004 was retrospectively analyzed. There were 1822 eligible patients who underwent colonoscopy (with a mean age of 5...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i47.7684

    authors: Rerknimitr R,Ratanapanich W,Kongkam P,Kullavanijaya P

    更新日期:2006-12-21 00:00:00

  • Is rectal cancer prone to metastasize to lymph nodes than colon cancer?

    abstract::The biology of colorectal cancer differs according to its location within the large intestine. A report published in a previous issue of World Journal of Gastroenterology (November 2010) evaluated the importance of tumor location as a risk factor for lymph node metastasis in colorectal cancer, and showed that rectal c...

    journal_title:World journal of gastroenterology

    pub_type: 评论,信件

    doi:10.3748/wjg.v17.i29.3465

    authors: Akiyoshi T,Watanabe T,Ueno M,Muto T

    更新日期:2011-08-07 00:00:00

  • Acute hepatitis C virus infection in a nurse trainee following a needlestick injury.

    abstract::Hepatitis C virus (HCV) infection after biological accident (needlestick injury) is a rare event. This report describes the first case of acute HCV infection after a needlestick injury in a female nursing student at Padua University Hospital. The student nurse was injured on the second finger of the right hand when re...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i4.581

    authors: Scaggiante R,Chemello L,Rinaldi R,Bartolucci GB,Trevisan A

    更新日期:2013-01-28 00:00:00

  • Pathological evolution of hepatitis C virus-"Healthy carriers".

    abstract:AIM:To determine factors associated with fibrosis progression in hepatitis C virus (HCV)-infected patients without significant initial pathological lesions. METHODS:Seventy six untreated HCV-infected patients with initially normal liver as defined by a Knodell score < or = 3, with 2 liver biopsies and detectable HCV-R...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.14.3861

    authors: Sobesky R,Lebray P,Nalpas B,Vallet-Pichard A,Fontaine H,Lagneau JL,Pol S

    更新日期:2008-06-28 00:00:00

  • Effects of herbal compound 861 on human hepatic stellate cell proliferation and activation.

    abstract:AIM:To investigate the effects of herbal compound 861 (Cpd 861) on cell proliferation in human hepatic stellate cells (LX-2) and human hepatocellular liver carcinoma cells (HepG2), and expression of alpha-smooth muscle actin (alpha-SMA) in LX-2 cells. METHODS:LX-2 and HepG2 cells were incubated with various concentrat...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i19.2831

    authors: Wang L,Wang J,Wang BE,Xiao PG,Qiao YJ,Tan XH

    更新日期:2004-10-01 00:00:00

  • Carcinosarcoma of the liver with mesenchymal differentiation.

    abstract::We report an extremely rare case where a mesenchymal differentiation, especially embryonal sarcoma, was demonstrated in cholangiocarcinoma. At autopsy, a yellowish-white tumor (15 cm x 12 cm) was found in the right hepatic lobe, and there were several daughter nodules in both hepatic lobes. Histologically, most of the...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i5.809

    authors: Sumiyoshi S,Kikuyama M,Matsubayashi Y,Kageyama F,Ide Y,Kobayashi Y,Nakamura H

    更新日期:2007-02-07 00:00:00

  • Diagnosis and treatment of iron-deficiency anemia in gastrointestinal bleeding: A systematic review.

    abstract:BACKGROUND:Anemia is considered a public health issue and is often caused by iron deficiency. Iron-deficiency anemia (IDA) often originates from blood loss from lesions in the gastrointestinal tract in men and postmenopausal women, and its prevalence among patients with gastrointestinal bleeding has been estimated to b...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v26.i45.7242

    authors: Cotter J,Baldaia C,Ferreira M,Macedo G,Pedroto I

    更新日期:2020-12-07 00:00:00

  • Prognostic and predictive biomarkers in metastatic colorectal cancer anti-EGFR therapy.

    abstract:AIM:To reviewing genetic and epigenetic make-up of metastatic colorectal cancers (mCRCs) addicted to epidermal growth factor receptor (EGFR) signalling. METHODS:The present study summarizes the potential value of prognostic and predictive biomarkers in selecting mCRC patients treated with anti-EGFR therapy. A meta-ana...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i30.6944

    authors: Lo Nigro C,Ricci V,Vivenza D,Granetto C,Fabozzi T,Miraglio E,Merlano MC

    更新日期:2016-08-14 00:00:00

  • Effects of premedication with Pronase for endoscopic ultrasound of the stomach: A randomized controlled trial.

    abstract:AIM:To analyze the effects of premedication with Pronase for endoscopic ultrasound (EUS) examination of the stomach. METHODS:This was a prospective, randomized and controlled clinical study. All patients were randomly assigned to either the Pronase group or placebo group. The pretreatment solution was a mixed solution...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v22.i48.10673

    authors: Wang GX,Liu X,Wang S,Ge N,Guo JT,Sun SY

    更新日期:2016-12-28 00:00:00

  • Incidence of hepatocellular carcinoma in outpatients with cirrhosis in Brazil: A 10-year retrospective cohort study.

    abstract:AIM:To determine the incidence of hepatocellular carcinoma (HCC) and the impact of HCC surveillance on early diagnosis and survival of cirrhotic outpatients. METHODS:In this retrospective cohort study, cirrhotic outpatients undergoing HCC surveillance between March 2005 and March 2014 were analyzed. Exclusion criteria...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i46.10219

    authors: Appel-da-Silva MC,Miozzo SA,Dossin IA,Tovo CV,Branco F,de Mattos AA

    更新日期:2016-12-14 00:00:00

  • Nestin in gastrointestinal and other cancers: effects on cells and tumor angiogenesis.

    abstract::Nestin is a class VI intermediate filament protein that was originally described as a neuronal stem cell marker during central nervous system (CNS) development, and is currently widely used in that capacity. Nestin is also expressed in non-neuronal immature or progenitor cells in normal tissues. Under pathological con...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v17.i4.409

    authors: Ishiwata T,Matsuda Y,Naito Z

    更新日期:2011-01-28 00:00:00

  • Improvement of diabetes and hypertension after gastrectomy: a nationwide cohort study.

    abstract:AIM:To evaluate the effect of gastrectomy on diabetes mellitus (DM) and hypertension (HTN) in non-obese gastric cancer patients. METHODS:A total of 100000 patients, diagnosed with either type 2 DM or HTN, were randomly selected from the 2004 Korean National Health Insurance System claims. Among them, 360 diabetes and ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i4.1173

    authors: Lee EK,Kim SY,Lee YJ,Kwak MH,Kim HJ,Choi IJ,Cho SJ,Kim YW,Lee JY,Kim CG,Yoon HM,Eom BW,Kong SY,Yoo MK,Park JH,Ryu KW

    更新日期:2015-01-28 00:00:00