Differences in characteristics of colorectal neoplasm between young and elderly Thais.


AIM:To analyze the differences of clinical characteristics of colorectal neoplasm including polyps between the elderly and young Thai patients. METHODS:Colonoscopy database from December 2000 to October 2004 was retrospectively analyzed. There were 1822 eligible patients who underwent colonoscopy (with a mean age of 56.6 years). Patients were classified into two groups: the older age group (aged > or = 60 years; n = 989) and the younger age group (aged < 60 years; n = 833). Data were recorded on age, colonoscopic indications, tumor location, colonoscopic findings and their related histological findings. RESULTS:Colorectal malignancy related lesions were more often found in the older age group (21%) than in the younger age group (12%). Left-sided lesions were detected more commonly than right-sided in both age groups in approximately two-thirds of all cases. Hematochezia showed greater association with left-sided lesions in the elderly. No relationship was found between age and neoplasm staging and severity. CONCLUSION:The chance of detecting colorectal neoplasm by colonoscopy was higher in the elderly than in the young Thais. However, both groups had the lesions predominantly located in the left side.


World J Gastroenterol


Rerknimitr R,Ratanapanich W,Kongkam P,Kullavanijaya P




Has Abstract


2006-12-21 00:00:00












  • Prognostic value of KIT mutation in gastrointestinal stromal tumors.

    abstract:AIM:To examine the prevalence and prognostic significance of C-kit gene mutation and analysis the correlation of C-kit gene mutation and the clinicalpathologic parameters of GISTs. METHODS:Eighty-two GISTs were studied for the mutation of C-kit gene by PCR-SSCP, DNA sequence. Statistical comparison were used to analys...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Liu XH,Bai CG,Xie Q,Feng F,Xu ZY,Ma DL

    更新日期:2005-07-07 00:00:00

  • Efficacy of mycofenolate mofetil for steroid-resistant acute rejection after living donor liver transplantation.

    abstract:AIM:To discuss the use of mycophenolate mofetil (MMF) as an immunosuppressant in steroid resistant rejection after liver transplantation. METHODS:The clinical records of 260 adult patients who underwent living donor liver transplantation (LDLT) were reviewed. Tacrolimus and methylprednisolone were used for primary imm...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Akamatsu N,Sugawara Y,Tamura S,Matsui Y,Kaneko J,Makuuchi M

    更新日期:2006-08-14 00:00:00

  • Chronic hepatitis B in children with or without malignancies: a 13-year follow-up.

    abstract:AIM:To evaluate the outcome of chronic hepatitis B (CHB) in children with or without malignancies. METHODS:Twenty four children (15 boys and 9 girls) with malignancies, followed up by the pediatric gastroenterology outpatient clinic for CHB between January 2000 and December 2013, were enrolled in the study (Group 1). ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Usta M,Urgancı N,Yıldırmak ZY,Dogan Vural S

    更新日期:2015-02-21 00:00:00

  • Human epidermal growth factor receptor-2 in oesophageal cancers: an observational study.

    abstract:AIM:To determine the incidence of human epidermal growth factor receptor 2 (HER2) over expression in oesophageal cancers. METHODS:A retrospective study, of one hundred consecutive cases of endoscopic histological samples of oesophageal cancers from a single British cancer network were included. Cancer cases were diagn...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Al-Momani H,Barnes R,El-Hadi A,Shah R,Lewis WG,Edwards P

    更新日期:2012-11-28 00:00:00

  • Intestinal perforation after combined liver-kidney transplantation for a case of congenital polycystic disease.

    abstract:AIM:To highlight the intestinal perforation (IP), an uncommon and catastrophic complication after combined liver-kidney transplantation. METHODS:Combined liver-kidney transplantation (LKTx) with left kidney excision and a cyst fenestration procedure on the right kidney were performed on a case of 46-year-old female wi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Peng T,Peng MH,Li LQ,Deng YL,Yang DH,Lu BY,Chen XG,Guo Y,Xiao KY,Chen B,Zhong Q,Wei MY

    更新日期:2004-09-15 00:00:00

  • Alcoholism and liver disease in Mexico: genetic and environmental factors.

    abstract::Alcoholism and cirrhosis, which are two of the most serious health problems worldwide, have a broad spectrum of clinical outcomes. Both diseases are influenced by genetic susceptibility and cultural traits that differ globally but are specific for each population. In contrast to other regions around the world, Mexican...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Roman S,Zepeda-Carrillo EA,Moreno-Luna LE,Panduro A

    更新日期:2013-11-28 00:00:00

  • Effects of palmatine on potassium and calcium currents in isolated rat hepatocytes.

    abstract:AIM:To study the effects of palmatine, a known inhibitor on delayed rectifier potassium current and L-type calcium current (I(Ca,L)) in guinea pig ventricular myocytes, on the potassium and calcium currents in isolated rat hepatocytes. METHODS:Tight-seal whole-cell patch-clamp techniques were performed to investigate ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Wang F,Zhou HY,Cheng L,Zhao G,Zhou J,Fu LY,Yao WX

    更新日期:2003-02-01 00:00:00

  • Cellular DNA repair cofactors affecting hepatitis B virus infection and replication.

    abstract:AIM:To investigate whether hepatitis B virus (HBV) infection activates DNA damage response and DNA repair cofactors inhibit HBV infection and replication. METHODS:Human hepatocyte cell line HL7702 was studied. Immunoblotting was performed to test the expression of ataxia telangiectasia-mutated (ATM)-Rad3-related prote...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Zhao F,Hou NB,Song T,He X,Zheng ZR,Ma QJ,Li L,Zhang YH,Zhong H

    更新日期:2008-08-28 00:00:00

  • Tumor necrosis factor alpha receptor 1 deficiency in hepatocytes does not protect from non-alcoholic steatohepatitis, but attenuates insulin resistance in mice.

    abstract:BACKGROUND:End-stage liver disease caused by non-alcoholic steatohepatitis (NASH) is the second leading indication for liver transplantation. To date, only moderately effective pharmacotherapies exist to treat NASH. Understanding the pathogenesis of NASH is therefore crucial for the development of new therapies. The in...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Bluemel S,Wang Y,Lee S,Schnabl B

    更新日期:2020-09-07 00:00:00

  • Development of hepatorenal syndrome in bile duct ligated rats.

    abstract:AIM:To evaluate in bile duct ligated rats whether there were progressive alterations of renal function without changes in histopathology. METHODS:Male Wistar rats were submitted to sham-surgery or bile duct ligation (BDL) and divided according to the post-procedure time (2, 4 and 6-wk). To determine renal function par...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Pereira RM,dos Santos RA,Oliveira EA,Leite VH,Dias FL,Rezende AS,Costa LP,Barcelos LS,Teixeira MM,Simoes e Silva AC

    更新日期:2008-07-28 00:00:00

  • Pernicious anemia: new insights from a gastroenterological point of view.

    abstract::Pernicious anemia (PA) is a macrocytic anemia that is caused by vitamin B(12) deficiency, as a result of intrinsic factor deficiency. PA is associated with atrophic body gastritis (ABG), whose diagnosis is based on histological confirmation of gastric body atrophy. Serological markers that suggest oxyntic mucosa damag...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审


    authors: Lahner E,Annibale B

    更新日期:2009-11-07 00:00:00

  • Effects of recombinant human growth hormone on rat septic shock with intraabdominal infection by E. coli.

    abstract:AIM:To investigate the therapeutic effects of recombinant human growth hormone (rhGH) on rat septic shock with intraabdominal infection by E. coli and its possible mechanism. METHODS:76 SD rats were divided into 3 groups randomly: control group (group C, n=16) without any special treatment, septic shock group (group S...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Huang Y,Wang SR,Yi C,Ying MY,Lin Y,Zhi MH

    更新日期:2002-12-01 00:00:00

  • Survival outcome of patients with spontaneously ruptured hepatocellular carcinoma treated surgically or by transarterial embolization.

    abstract:AIM:To evaluate clinical outcomes of patients that underwent surgery, transarterial embolization (TAE), or supportive care for spontaneously ruptured hepatocellular carcinoma (HCC). METHODS:A consecutive 54 patients who diagnosed as spontaneously ruptured HCC at our institution between 2003 and 2012 were retrospective...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Jin YJ,Lee JW,Park SW,Lee JI,Lee DH,Kim YS,Cho SG,Jeon YS,Lee KY,Ahn SI

    更新日期:2013-07-28 00:00:00

  • miR-30b inhibits autophagy to alleviate hepatic ischemia-reperfusion injury via decreasing the Atg12-Atg5 conjugate.

    abstract:AIM:To explore the role and potential mechanism of miR-30b regulation of autophagy in hepatic ischemia-reperfusion injury (IRI). METHODS:An animal model of hepatic IRI was generated in C57BL/6 mice. For in vitro studies, AML12 cells were immersed in mineral oil for 1 h and then cultured in complete Dulbecco's Modified...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Li SP,He JD,Wang Z,Yu Y,Fu SY,Zhang HM,Zhang JJ,Shen ZY

    更新日期:2016-05-14 00:00:00

  • Risk factors and outcome of bacterial infections in cirrhosis.

    abstract::Viable and non-viable pathological bacterial translocation promote a self-perpetuating circle of dysfunctional immune activation and systemic inflammation facilitating infections and organ failure in advanced cirrhosis. Bacterial infections and sepsis are now recognized as a distinct stage in the natural progression o...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Bruns T,Zimmermann HW,Stallmach A

    更新日期:2014-03-14 00:00:00

  • Effect of composite yogurt enriched with acacia fiber and Bifidobacterium lactis.

    abstract:AIM:To investigate whether composite yogurt with acacia dietary fiber and Bifidobacterium lactis (B. lactis) has additive effects in irritable bowel syndrome (IBS). METHODS:A total of 130 patients were randomly allocated to consume, twice daily for 8 wk, either the composite yogurt or the control product. The composit...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验


    authors: Min YW,Park SU,Jang YS,Kim YH,Rhee PL,Ko SH,Joo N,Kim SI,Kim CH,Chang DK

    更新日期:2012-09-07 00:00:00

  • Atrial fibrillation and gastroesophageal reflux disease: From the cardiologist perspective.

    abstract::We have read with interest the paper by Roman C. and colleagues discussing the relationship between gastroesophageal reflux disease and atrial fibrillation. The review is presenting the available evidence for the common pathogenic mechanisms. However, from a cardiologist perspective, some available data were not highl...

    journal_title:World journal of gastroenterology

    pub_type: 评论,杂志文章


    authors: Floria M,Drug VL

    更新日期:2015-03-14 00:00:00

  • Validation of the chronic liver disease questionnaire in Serbian patients.

    abstract:AIM:To translate into Serbian and to investigate the validity of the cross-culturally adapted the chronic liver disease questionnaire (CLDQ). METHODS:The questionnaire was validated in 103 consecutive CLD patients treated between October 2009 and October 2010 at the Clinic for Gastroenterology, Clinical Centre of Serb...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Popovic DDj,Kovacevic NV,Kisic Tepavcevic DB,Trajkovic GZ,Alempijevic TM,Spuran MM,Krstic MN,Jesic RS,Younossi ZM,Pekmezovic TD

    更新日期:2013-08-14 00:00:00

  • Micronucleus analysis in patients with colorectal adenocarcinoma and colorectal polyps.

    abstract:AIM:To determine, by counting micronucleus (MN) frequencies, whether chromosomal or DNA damage have an effect on the pathogenesis of early colorectal adenocarcinoma (CRC). METHODS:We analyzed MN frequencies in 21 patients with CRC, 24 patients with colon polyps [10 neoplastic polyps (NP) and 14 non-neoplastic polyps (...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Karaman A,Binici DN,Kabalar ME,Calikuşu Z

    更新日期:2008-11-28 00:00:00

  • Novel method for extracting exosomes of hepatocellular carcinoma cells.

    abstract:AIM:To develop a novel method for the rapid and efficient extraction of exosomes secreted by tumor cells. METHODS:Unlike the traditional extraction method, the supernatants of cell cultures were concentrated, and the exosomes were isolated promptly and effectively using a novel nanomaterial called ExoQuick. Coomassie ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Zhu L,Qu XH,Sun YL,Qian YM,Zhao XH

    更新日期:2014-06-07 00:00:00

  • Correlation of fibrinogen-like protein 2 with progression of acute pancreatitis in rats.

    abstract:AIM:To examine fibrinogen-like protein 2 (fgl2) expression during taurocholate-induced acute pancreatitis progression in rats and its correlation with pancreatic injury severity. METHODS:Forty-eight male Sprague-Dawley rats were randomly divided into the severe acute pancreatitis (SAP) group (n = 24) and the sham oper...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Ye XH,Chen TZ,Huai JP,Lu GR,Zhuge XJ,Chen RP,Chen WJ,Wang C,Huang ZM

    更新日期:2013-04-28 00:00:00

  • Positron emission tomography/computer tomography in guidance of extrahepatic hepatocellular carcinoma metastasis management.

    abstract::Hepatocellular carcinoma (HCC) is one of the most common primary cancers in the world. Surgery is the gold standard for treatment of patients with HCC. Recurrence and metastasis are the major obstacles to further improve the prognosis of HCC. Most recurrences are intrahepatic. However, 30% of the recurrences are extra...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Sun L,Guan YS,Pan WM,Chen GB,Luo ZM,Wu H

    更新日期:2007-10-28 00:00:00

  • Value of transient elastography for the prediction of variceal bleeding.

    abstract:AIM:To determine if liver stiffness (LS) measurements by means of transient elastography (TE) correlate with the presence of significant esophageal varices (EV) and if they can predict the occurrence of variceal bleeding. METHODS:We studied 1000 cases of liver cirrhosis divided into 2 groups: patients without EV or wi...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Sporea I,Raţiu I,Sirli R,Popescu A,Bota S

    更新日期:2011-05-07 00:00:00

  • Case of plasmablastic lymphoma of the sigmoid colon and literature review.

    abstract::Plasmablastic lymphoma (PBL) is a rare form of non-Hodgkin's lymphoma that is associated with human immunodeficiency virus (HIV) infection. Although PBL is most commonly observed in the oral cavity of HIV-positive patients, it can also be observed at extra-oral sites in HIV-negative patients. This report represents an...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审


    authors: Haramura T,Haraguchi M,Irie J,Ito S,Tokai H,Noda K,Kitajima M,Minami S,Inoue K,Sasaki Y,Oshima K,Eguchi S

    更新日期:2015-06-28 00:00:00

  • Endoscopic ultrasound-guided biliary drainage: Bilateral systems drainage via left duct approach.

    abstract::Endoscopic ultrasound (EUS)-guided biliary drainage is accepted as a less invasive, alternative treatment for patients in whom endoscopic retrograde cholangiopancreatography has failed. Most patients with malignant hilar obstruction undergo EUS-guided hepaticogastrostomy. The authors present the case of a 77-year-old ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Prachayakul V,Aswakul P

    更新日期:2015-09-14 00:00:00

  • Phase I clinical study of personalized peptide vaccination combined with radiotherapy for advanced hepatocellular carcinoma.

    abstract:AIM:To assess the efficacy and safety of a new treatment modality, cellular immune therapy based on personalized peptide vaccination (PPV-DC-CTL) combined with radiotherapy, for treating advanced hepatocellular carcinoma (HCC). METHODS:A total of nine patients with advanced HCC were enrolled. Multidisciplinary consult...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Shen J,Wang LF,Zou ZY,Kong WW,Yan J,Meng FY,Chen FJ,Du J,Shao J,Xu QP,Ren HZ,Li RT,Wei J,Qian XP,Liu BR

    更新日期:2017-08-07 00:00:00

  • Efficacy of noninvasive evaluations in monitoring inflammatory bowel disease activity: A prospective study in China.

    abstract:AIM:To optimize the efficacy of noninvasive evaluations in monitoring the endoscopic activity of inflammatory bowel disease (IBD). METHODS:Fecal calprotectin (FC), clinical activity index (CDAI or CAI), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and procalcitonin (PCT) were measured for 136 IBD pa...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Chen JM,Liu T,Gao S,Tong XD,Deng FH,Nie B

    更新日期:2017-12-14 00:00:00

  • G and D cells in rat antral mucosa: an immunoelectron microscopic study.

    abstract:AIM:To investigate the gastrin secreting cells (G cells) and the somatostatin secreting cells (D cells) of antral mucosa in rats at the ultrastructural level. METHODS:Revised immunoelectron microscopic technique was used to detect the G cells and D cells in rat antral mucosa through gastrin and somatostatin antibodies...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Sun FP,Song YG

    更新日期:2003-12-01 00:00:00

  • Preparation of monoclonal antibody against apoptosis-associated antigens of hepatoma cells by subtractive immunization.

    abstract:AIM:To elucidate the expression of the apoptosis-associated molecules in human primary hepatocellular carcinoma (HCC) cells, and prepare the monoclonal antibodies (mAb) against the apoptosis-associated antigens of HCC cells. METHODS:Human HCC cell line HCC-9204 cells were induced apoptosis with 60 mL x L(-1) ethanol f...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Yang LJ,Wang WL

    更新日期:2002-10-01 00:00:00

  • Mechanical properties of hepatocellular carcinoma cells.

    abstract:AIM:To study the viscoelastic properties of human hepatocytes and hepatocellular carcinoma (HCC) cells under cytoskeletal perturbation, and to further to study the viscoelastic properties and the adhesive properties of mouse hepatoma cells (HTC) in different cell cycle. METHODS:Micropipette aspiration technique was ad...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章


    authors: Zhang G,Long M,Wu ZZ,Yu WQ

    更新日期:2002-04-01 00:00:00