Length of negative resection margin does not affect local recurrence and survival in the patients with gastric cancer.

Abstract:

AIM:To investigate the influence of the resection margin on local recurrence and survival in gastric cancer patients. METHODS:We reviewed the medical records of 1788 patients who had undergone gastrectomy for gastric cancer at the Seoul National University Bundang Hospital, South Korea, between May 2003 and July 2009. The patients were divided into early and advanced gastric cancer groups. In each group, we analyzed the relationship between clinicopathologic factors and survival outcomes, and compared the hazard rates of event occurrence between patients with resection margins above and below the cut-off value, using a Cox proportional hazard model. RESULTS:The early and advanced gastric cancer groups included 1001 and 787 patients, respectively. The hazard rates of event occurrence did not significantly differ between the patients with resection margins above the cut-off value and those with resection margins below the cut-off value (P > 0.05, in all comparisons). Based on the multivariable analyses, the proximal and distal resection margins were not significantly associated with survival outcomes and local recurrence (P > 0.05, in all analyses). CONCLUSION:The proximal or distal resection margins did not affect the prognosis of patients with gastric cancer if the margins were pathologically negative.

journal_name

World J Gastroenterol

authors

Lee CM,Jee YS,Lee JH,Son SY,Ahn SH,Park DJ,Kim HH

doi

10.3748/wjg.v20.i30.10518

subject

Has Abstract

pub_date

2014-08-14 00:00:00

pages

10518-24

issue

30

eissn

1007-9327

issn

2219-2840

journal_volume

20

pub_type

杂志文章
  • Coexistence of hepatoma with mantle cell lymphoma in a hepatitis B carrier.

    abstract::The coexistence of hepatocellular carcinoma (HCC) and non-Hodgkin's lymphoma (NHL) in the liver is rare. Reports show that these patients have cirrhotic livers or hepatitis virus infections before they develop HCC and NHL. We present a patient with hepatitis B virus infection who was transferred to our hospital with a...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v21.i45.12981

    authors: Lee MH,Lin YC,Cheng HT,Chuang WY,Huang HC,Kao HW

    更新日期:2015-12-07 00:00:00

  • Anti-Helicobacter pylori therapy significantly reduces Helicobacter pylori -induced gastric mucosal damage in Mongolian gerbils.

    abstract:AIM:To investigate the effectiveness of 4 d' anti-Helicobacter pylori therapy on the H pylori-infected Mongolian gerbils based on physiological and pathological changes. METHODS:We used 6-wk-old male gerbils orally inoculated with H pylori (ATCC43504, 2X10(8) CFU/mL). Seven weeks after H pylori inoculation, the animal...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i7.982

    authors: Chang CC,Chen SH,Lien GS,Lee YJ,Lou HY,Hsieh CR,Fang CL,Pan S

    更新日期:2005-02-21 00:00:00

  • Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava.

    abstract::Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). T...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.15.4204

    authors: Tomimaru Y,Nagano H,Marubashi S,Kobayashi S,Eguchi H,Takeda Y,Tanemura M,Kitagawa T,Umeshita K,Hashimoto N,Yoshikawa H,Wakasa K,Doki Y,Mori M

    更新日期:2009-09-07 00:00:00

  • Clinical usefulness of adherence to gastro-esophageal reflux disease guideline by Spanish gastroenterologists.

    abstract:AIM:To investigate usefulness of adherence to gastro-esophageal reflux disease (GERD) guideline established by the Spanish Association of Gastroenterology. METHODS:Prospective, observational and multicentre study of 301 patients with typical symptoms of GERD who should be managed in accordance with guidelines and were...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v18.i35.4885

    authors: Mearin F,Ponce J,Ponce M,Balboa A,González MA,Zapardiel J

    更新日期:2012-09-21 00:00:00

  • Microbiota-based treatments in alcoholic liver disease.

    abstract::Gut microbiota plays a key role in the pathogenesis of alcoholic liver disease (ALD). Consumption of alcohol leads to increased gut permeability, small intestinal bacterial overgrowth, and enteric dysbiosis. These factors contribute to the increased translocation of microbial products to the liver via the portal tract...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i29.6673

    authors: Sung H,Kim SW,Hong M,Suk KT

    更新日期:2016-08-07 00:00:00

  • Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells.

    abstract:AIM:To investigate and compare the hepatogenic transdifferentiation of adipose tissue-derived stem cells (ADSC) and bone marrow-derived mesenchymal stem cells (BMSC) in vitro. Transdifferentiation of BMSC into hepatic cells in vivo has been described. Adipose tissue represents an accessible source of ADSC, with similar...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i36.5834

    authors: Taléns-Visconti R,Bonora A,Jover R,Mirabet V,Carbonell F,Castell JV,Gómez-Lechón MJ

    更新日期:2006-09-28 00:00:00

  • Prognostic and predictive significance of MSI in stages II/III colon cancer.

    abstract::In colon cancer, classic disease staging remains the key prognosis and treatment determinant. Although adjuvant chemotherapy has an established role in stage III colon cancer patients, in stage II it is still a subject of controversy due to its restriction to a small subgroup of patients with high-risk histopathologic...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i22.6809

    authors: Saridaki Z,Souglakos J,Georgoulias V

    更新日期:2014-06-14 00:00:00

  • Effects of hemoperfusion adsorption and/or plasma exchange in treatment of severe viral hepatitis: a comparative study.

    abstract:AIM:Non-bioartificial liver has been applied to clinic for quite a long time, but the reported efficacy has been very different. The aim of this study was to compare the efficacy and safety of hemoperfusion adsorption, plasma exchange and plasma exchange plus hemoperfusion adsorption in treatment of severe viral hepati...

    journal_title:World journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.3748/wjg.v10.i8.1218

    authors: He NH,Wang YJ,Wang ZW,Liu J,Li JJ,Liu GD,Wang YM

    更新日期:2004-04-15 00:00:00

  • Serum vitamin D and colonic vitamin D receptor in inflammatory bowel disease.

    abstract:AIM:To determine serum vitamin D levels and colonic vitamin D receptor (VDR) expression in inflammatory bowel disease (IBD) and non-IBD patients and correlate these with histopathology. METHODS:Puerto Rican IBD (n = 10) and non-IBD (n = 10) patients ≥ 21 years old scheduled for colonoscopy were recruited. Each patient...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i13.3581

    authors: Abreu-Delgado Y,Isidro RA,Torres EA,González A,Cruz ML,Isidro AA,González-Keelan CI,Medero P,Appleyard CB

    更新日期:2016-04-07 00:00:00

  • Pediatric non-alcoholic fatty liver disease: Recent solutions, unresolved issues, and future research directions.

    abstract::Non-alcoholic fatty liver disease (NAFLD) in children is becoming a major health concern. A "multiple-hit" pathogenetic model has been suggested to explain the progressive liver damage that occurs among children with NAFLD. In addition to the accumulation of fat in the liver, insulin resistance (IR) and oxidative stre...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v22.i36.8078

    authors: Clemente MG,Mandato C,Poeta M,Vajro P

    更新日期:2016-09-28 00:00:00

  • Antineoplastic effects of octreotide on human gallbladder cancer cells in vitro.

    abstract:AIM:To investigate whether octreotide can inhibit the growth of human gallbladder cancer cells in vitro and to elucidate the antineoplastic mechanism of octreotide in gallbladder cancer. METHODS:A human gallbladder cancer cell line, GBC-SD, was cultured in vitro. The antiproliferative effects of octreotide were examin...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v10.i7.1043

    authors: Wang JH,Xing QT,Yuan MB

    更新日期:2004-04-01 00:00:00

  • Colorectal cancer: Parametric evaluation of morphological, functional and molecular tomographic imaging.

    abstract::Colorectal cancer (CRC) represents one of the leading causes of tumor-related deaths worldwide. Among the various tools at physicians' disposal for the diagnostic management of the disease, tomographic imaging (e.g., CT, MRI, and hybrid PET imaging) is considered essential. The qualitative and subjective evaluation of...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v25.i35.5233

    authors: Mainenti PP,Stanzione A,Guarino S,Romeo V,Ugga L,Romano F,Storto G,Maurea S,Brunetti A

    更新日期:2019-09-21 00:00:00

  • Endoscopic submucosal dissection for early esophageal neoplasms using the stag beetle knife.

    abstract:AIM:To determine short- and long-term outcomes of endoscopic submucosal dissection (ESD) using the stag beetle (SB) knife, a scissor-shaped device. METHODS:Seventy consecutive patients with 96 early esophageal neoplasms, who underwent ESD using a SB knife at Kure Medical Center and Chugoku Cancer Center, Japan, betwee...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v24.i15.1632

    authors: Kuwai T,Yamaguchi T,Imagawa H,Miura R,Sumida Y,Takasago T,Miyasako Y,Nishimura T,Iio S,Yamaguchi A,Kouno H,Kohno H,Ishaq S

    更新日期:2018-04-21 00:00:00

  • Effects of combined pre- and post-natal protein deprivation on the myenteric plexus of the esophagus of weanling rats: a histochemical, quantitative and ultrastructural study.

    abstract:AIM:To evaluate the effects of protein deprivation on the myenteric plexus of the esophagus of weanling rats. METHODS:Pregnant female Wistar rats were divided into 2 groups: nourished (N), receiving normal diet, and undernourished (D), receiving a protein-deprived diet, which continued after birth. At twenty-one days ...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v13.i26.3598

    authors: Liberti EA,Fontes RB,Fuggi VM,Maifrino LB,Souza RR

    更新日期:2007-07-14 00:00:00

  • Endoscopic trans-esophageal submucosal tunneling surgery: A new therapeutic approach for diseases located around the aorta ventralis.

    abstract:AIM:To assess the efficiency of endoscopic trans-esophageal submucosal tunneling surgery (EESTS) technique for diseases located around the aorta ventralis. METHODS:Nine pigs were assigned to EESTs. The procedures were as follows: First, a long esophageal submucosal tunnel was established. Second, full-thickness myotom...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v25.i1.85

    authors: Xiong Y,Chen QQ,Chai NL,Jiao SC,Ling Hu EQ

    更新日期:2019-01-07 00:00:00

  • Spices, herbal xenobiotics and the stomach: friends or foes?

    abstract::Spices and herbal remedies have been used since ancient times to treat a variety of disorders. It has been experimentally demonstrated that spices, herbs, and their extracts possess antimicrobial, anti-inflammatory, antirheumatic, lipid-lowering, hepatoprotective, nephroprotective, antimutagenic and anticancer activit...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.v16.i22.2710

    authors: Al Mofleh IA

    更新日期:2010-06-14 00:00:00

  • Management of patients with sphincter of Oddi dysfunction based on a new classification.

    abstract:AIM:To propose a new classification system for sphincter of Oddi dysfunction (SOD) based on clinical data of patients. METHODS:The clinical data of 305 SOD patients documented over the past decade at our center were analyzed retrospectively, and typical cases were reported. RESULTS:The new classification with two mor...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v17.i3.385

    authors: Gong JQ,Ren JD,Tian FZ,Jiang R,Tang LJ,Pang Y

    更新日期:2011-01-21 00:00:00

  • Early colon cancer within a diverticulum treated by magnifying chromoendoscopy and laparoscopy.

    abstract::We report a unique case of intramucosal carcinoma in a tubulovillous adenoma arising from a single diverticulum. Endoscopic mucosal resection (EMR) was carried out successfully and completely with the assistance of laparoscopy. A 71-year-old man was admitted to our hospital because of melena and anemia. Emergent colon...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v16.i12.1545

    authors: Fu KI,Hamahata Y,Tsujinaka Y

    更新日期:2010-03-28 00:00:00

  • Pre- and postoperative systemic hemodynamic evaluation in patients subjected to esophagogastric devascularization plus splenectomy and distal splenorenal shunt: a comparative study in schistomomal portal hypertension.

    abstract:AIM:To investigate the systemic hemodynamic effects of two surgical procedures largely employed for treatment of schistosomal portal hypertension. METHODS:Thirty-six patients undergoing elective surgical treatment of portal hypertension due to hepatosplenic mansonic schistosomiasis were prospectively evaluated. All pa...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3748/wjg.v13.i41.5471

    authors: de Cleva R,Herman P,D'albuquerque LA,Pugliese V,Santarem OL,Saad WA

    更新日期:2007-11-07 00:00:00

  • Changing patterns of colorectal cancer in China over a period of 20 years.

    abstract:AIM:To determine whether any changes have occurred on the patterns of colorectal cancer in China. METHODS:Data from 21 Chinese articles published from 1980 to 1999, were used to analyze the time trend of colorectal cancer according to the patients' age at diagnosis, sex, the site of the tumor, stage, and the pathology...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i30.4685

    authors: Li M,Gu J

    更新日期:2005-08-14 00:00:00

  • Preparation of monoclonal antibody against apoptosis-associated antigens of hepatoma cells by subtractive immunization.

    abstract:AIM:To elucidate the expression of the apoptosis-associated molecules in human primary hepatocellular carcinoma (HCC) cells, and prepare the monoclonal antibodies (mAb) against the apoptosis-associated antigens of HCC cells. METHODS:Human HCC cell line HCC-9204 cells were induced apoptosis with 60 mL x L(-1) ethanol f...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v8.i5.808

    authors: Yang LJ,Wang WL

    更新日期:2002-10-01 00:00:00

  • Treatment of gastrointestinal bleeding in left ventricular assist devices: A comprehensive review.

    abstract::Left ventricular assist devices (LVAD) are increasingly become common as life prolonging therapy in patients with advanced heart failure. Current devices are now used as definitive treatment in some patients given the improved durability of continuous flow pumps. Unfortunately, continuous flow LVADs are fraught with c...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v26.i20.2550

    authors: Vedachalam S,Balasubramanian G,Haas GJ,Krishna SG

    更新日期:2020-05-28 00:00:00

  • Differential expression of apoptosis related proteins and nitric oxide synthases in Epstein Barr associated gastric carcinomas.

    abstract:AIM:To determine the incidence of Epstein Barr virus associated gastric carcinoma (GC) in Brazil and compare the expressions of apoptosis related proteins and nitric oxide synthases between EBV positive and negative gastric carcinoma. METHODS:In situ hybridization of EBV-encoded small RNA-1 (EBER-1) and PCR was perfor...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v12.i31.4959

    authors: Begnami MD,Montagnini AL,Vettore AL,Nonogaki S,Brait M,Simoes-Sato AY,Seixas AQ,Soares FA

    更新日期:2006-08-21 00:00:00

  • Targeted medical therapy of biliary tract cancer: recent advances and future perspectives.

    abstract::The limited efficacy of cytotoxic therapy for advanced biliary tract and gallbladder cancers emphasizes the need for novel and more effective medical treatment options. A better understanding of the specific biological features of these neoplasms led to the development of new targeted therapies, which take the abundan...

    journal_title:World journal of gastroenterology

    pub_type: 社论,评审

    doi:10.3748/wjg.14.7021

    authors: Hopfner M,Schuppan D,Scherubl H

    更新日期:2008-12-14 00:00:00

  • Long-term outcome in patients with obscure gastrointestinal bleeding after negative capsule endoscopy.

    abstract:AIM:To investigate long-term outcome in obscure gastrointestinal bleeding (OGIB) after negative capsule endoscopy (CE) and identify risk factors for rebleeding. METHODS:A total of 113 consecutive patients underwent CE for OGIB from May 2003 to June 2010 at Seoul National University Hospital. Ninety-five patients (84.1...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v19.i10.1632

    authors: Koh SJ,Im JP,Kim JW,Kim BG,Lee KL,Kim SG,Kim JS,Jung HC

    更新日期:2013-03-14 00:00:00

  • Successful treatment of ileal ulcers caused by immunosuppressants in two organ transplant recipients.

    abstract::Although gastroduodenal ulcers are common in solid organ transplant patients, there are few reports on multiple giant ulcers in the distal ileum and ileocecal valve caused by immunosuppressants Herein, we report on a liver transplant recipient and a renal transplant recipient with multiple large ulcers in the distal i...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v22.i24.5616

    authors: Guo YW,Gu HY,Abassa KK,Lin XY,Wei XQ

    更新日期:2016-06-28 00:00:00

  • Parameters of a severe disease course in ulcerative colitis.

    abstract:AIM:To detect high risk patients with a progressive disease course of ulcerative colitis (UC) requiring immunosuppressive therapy (IT). METHODS:A retrospective, multicenter analysis of 262 UC patients from eight German tertiary inflammatory bowel disease centres was performed. Patients were divided into two groups dep...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.3748/wjg.v20.i35.12574

    authors: Stallmach A,Nickel L,Lehmann T,Bokemeyer B,Bürger M,Hüppe D,Kruis W,Nikolaus S,Preiss JC,Sturm A,Teich N,Schmidt C

    更新日期:2014-09-21 00:00:00

  • Anti-HBV effect of liposome-encapsulated matrine in vitro and in vivo.

    abstract:AIM:To study the anti-HBV effect of liposome-encapsulated matrine (Lip-M) in vitro and in vivo. METHODS:2.2.15 cell line was cultured in vitro to observe the effect of Lip-M and matrine on the secretion of HBsAg and HBeAg. The toxicity of Lip-M and matrine to 2.2.15 cell line was also studied by MTT method. In in vivo...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v11.i3.426

    authors: Li CQ,Zhu YT,Zhang FX,Fu LC,Li XH,Cheng Y,Li XY

    更新日期:2005-01-21 00:00:00

  • Laparoscopic liver resection: wedge resections to living donor hepatectomy, are we heading in the right direction?

    abstract::Despite inception over 15 years ago and over 3000 completed procedures, laparoscopic liver resection has remained mainly in the domain of selected centers and enthusiasts. Requirement of extensive open liver resection (OLR) experience, in-depth understanding of anatomy and considerable laparoscopic technical expertise...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.3748/wjg.v20.i37.13369

    authors: Cherian PT,Mishra AK,Kumar P,Sachan VK,Bharathan A,Srikanth G,Senadhipan B,Rela MS

    更新日期:2014-10-07 00:00:00

  • Right hepatectomy for giant cavernous hemangioma with diffuse hemangiomatosis around Glisson's capsule.

    abstract::Diffuse liver hemangiomatosis with giant cavernous hemangioma in adult is extremely rare. A 35 year-old woman presented to hospital with main complaint of epigastric pain and abdominal fullness. An enhanced computed tomography scan revealed a massive liver tumor in right lobe about 150 mm in size. There was contrast e...

    journal_title:World journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3748/wjg.v20.i25.8312

    authors: Ohkura Y,Hashimoto M,Lee S,Sasaki K,Matsuda M,Watanabe G

    更新日期:2014-07-07 00:00:00