Anti-Helicobacter pylori therapy significantly reduces Helicobacter pylori -induced gastric mucosal damage in Mongolian gerbils.

abstract：AIM:To investigate biogenesis and intracellular localizations of clusterin to elucidate the potential molecular mechanisms implicated in tumorigenesis of esophageal mucosa. METHODS:Semi-quantitative RT-PCR for multi-region alteration analysis, Western blot for different transcriptional forms and immunohistochemical st...

journal_title：World journal of gastroenterology

authors： He HZ,Song ZM,Wang K,Teng LH,Liu F,Mao YS,Lu N,Zhang SZ,Wu M,Zhao XH

更新日期：2004-05-15 00:00:00

abstract：AIM:To describe the bowel habits and the prevalence of irritable bowel syndrome (IBS) and to investigate the influence of health behavior and social factors on IBS prevalence in university students. METHODS:This cross-sectional study was conducted at five major universities in Greater Beirut and its suburbs, between F...

journal_title：World journal of gastroenterology

authors： Costanian C,Tamim H,Assaad S

更新日期：2015-03-28 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. At the molecular level, GISTs can be categorized into two groups based on the causative oncogenic mutations. Approximately 85% of GISTs are caused by gain-of-function mutations in the tyrosine kinase receptor ...

journal_title：World journal of gastroenterology

authors： Zhao Y,Feng F,Guo QH,Wang YP,Zhao R

更新日期：2020-09-14 00:00:00

abstract：:The systemic therapies available for the management of Psoriasis (PsO) patients who cannot be treated with more conservative options, such as topical agents and/or phototherapy, with the exception of acitretin, can worsen or reactivate a chronic infection. Therefore, before administering immunosuppressive therapies wi...

journal_title：World journal of gastroenterology

authors： Bonifati C,Lora V,Graceffa D,Nosotti L

更新日期：2016-07-28 00:00:00

abstract：AIM:To investigate the efficacy of neoadjuvant chemoradiotherapy (NACRT) for resectability of locally advanced gastric cancer (LAGC). METHODS:Between November 2007 and January 2014, 29 patients with LAGC (clinically T3 with distal esophagus invasion/T4 or bulky regional node metastasis) that were treated with NACRT fo...

journal_title：World journal of gastroenterology

authors： Kim MS,Lim JS,Hyung WJ,Lee YC,Rha SY,Keum KC,Koom WS

更新日期：2015-03-07 00:00:00

abstract：:Esophageal cancer is an aggressive malignancy associated with dismal treatment outcomes. Presence of two distinct histopathological types distinguishes it from other gastrointestinal tract malignancies. Surgery is the cornerstone of treatment in locally advanced esophageal cancer (T2 or greater or node positive); howe...

journal_title：World journal of gastroenterology

authors： Garg PK,Sharma J,Jakhetiya A,Goel A,Gaur MK

更新日期：2016-10-21 00:00:00

abstract：:Cholangiocarcinoma is the second most common primary hepatic cancer. Despite advances in diagnostic techniques during the past decade, cholangiocarcinoma is usually encountered at an advanced stage. In this review, we describe the classification, diagnosis, and initial management of cholangiocarcinoma with obstructive...

journal_title：World journal of gastroenterology

authors： Tajiri T,Yoshida H,Mamada Y,Taniai N,Yokomuro S,Mizuguchi Y

更新日期：2008-05-21 00:00:00

abstract：AIM:To study the clinical outcome of antiviral therapy in hepatitis B-related decompensated cirrhotic patients. METHODS:Three hundred and twelve patients with decompensated hepatitis B cirrhosis were evaluated in a prospective cohort. With two years of follow-up, 198 patients in the group receiving antiviral therapy w...

journal_title：World journal of gastroenterology

authors： Li L,Liu W,Chen YH,Fan CL,Dong PL,Wei FL,Li B,Chen DX,Ding HG

更新日期：2013-12-07 00:00:00

abstract：:Inflammatory bowel diseases (IBDs) are characterized by a chronic course with an alternation of relapses and remissions. Questions about prognosis are important for the patient who wants to know how the disease will affect his/her life and also for clinicians to make management decisions. Correct selection of the pati...

journal_title：World journal of gastroenterology

authors： Modesto I,Perricone G,Orlando A,Cottone M

更新日期：2012-08-07 00:00:00

abstract：AIM:To summarize progress in the study of K-ras gene studies in pancreatic cancer and its potential clinical significance in screening test for early detection of pancreatic cancer, and to differentiate pancreatic cancer from chronic pancreatitis in recent decade. METHODS:Literature search (MEDLINE 1986-2003) was perf...

journal_title：World journal of gastroenterology

authors： Mu DQ,Peng YS,Xu QJ

更新日期：2004-02-15 00:00:00

abstract：AIM:To evaluate the long-term efficacy of endoscopic resection (ER) for small (≤ 4.0 cm) gastric gastrointestinal stromal tumors (GISTs) originating from the muscularis propria layer. METHODS:Between June 2005 and February 2015, we retrospectively analyzed 229 consecutive patients with gastric MP-GISTs who underwent E...

journal_title：World journal of gastroenterology

authors： Zhang Y,Mao XL,Zhou XB,Yang H,Zhu LH,Chen G,Ye LP

更新日期：2018-07-21 00:00:00

abstract：AIM:To assess the outcome of patients, who underwent transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) and subsequently liver transplantation (OLT) irrespective of tumor size when no tumor progression was observed. METHODS:Records, imaging studies and pathology of 84 patients with HCC were revi...

journal_title：World journal of gastroenterology

authors： Obed A,Beham A,Püllmann K,Becker H,Schlitt HJ,Lorf T

更新日期：2007-02-07 00:00:00

abstract：AIM:To investigate that both the neuronal function of the contractile system and structural apparatus of the gastrointestinal tract are affected in patients with longstanding diabetes and auto mic neuropathy. METHODS:The evoked esophageal and duodenal contractile activity to standardized bag distension was assessed us...

journal_title：World journal of gastroenterology

authors： Frokjaer JB,Andersen SD,Ejskjaer N,Funch-Jensen P,Drewes AM,Gregersen H

更新日期：2007-09-28 00:00:00

abstract：:Primary liver cancer is amongst the commonest tumors worldwide, particularly in parts of the developing world, and is increasing in incidence. Over the past three decades, surgical hepatic resection has evolved from a high risk, resource intensive procedure with limited application, to a safe and commonly performed op...

journal_title：World journal of gastroenterology

authors： Tsim NC,Frampton AE,Habib NA,Jiao LR

更新日期：2010-02-28 00:00:00

abstract：:Previously, we reported the efficacy of a newly developed inverted overtube in shortening the hemostatic time and obtaining a clear endoscopic view in emergency endoscopic hemostasis. This device also helped us to perform gastric endoscopic submucosal dissection (ESD) more safely by changing the direction of gravity i...

journal_title：World journal of gastroenterology

authors： Mori H,Rafiq K,Kobara H,Nishiyama N,Fujihara S,Yachida T,Ayagi M,Tani J,Miyoshi H,Masaki T

更新日期：2014-02-14 00:00:00

abstract：AIM:To determine the efficacy and safety of meticulous cannulation by needle-knife. METHODS:Three needle-knife procedures were used to facilitate cannulation in cases when standard cannulation techniques failed. A total of 104 cannulations via the minor papilla attempted in 74 patients at our center between January 20...

journal_title：World journal of gastroenterology

authors： Wang W,Gong B,Jiang WS,Liu L,Bielike K,Xv B,Wu YL

更新日期：2015-05-21 00:00:00

abstract：AIM:To clone and express the antigen of monoclonal antibody (MAb) PD4 for further investigation of its function. METHODS:MGC803 cDNA expression library was constructed and screened with PD4 as probes to clone the antigen. After failed in the library screening, immunoprecipitation and SDS-polyacrylamide gel electrophor...

journal_title：World journal of gastroenterology

authors： Ning JY,Sun GX,Huang S,Ma H,An P,Meng L,Song SM,Wu J,Shou CC

更新日期：2003-10-01 00:00:00

abstract：AIM:To describe our own experience with pyogenic liver abscesses over the past 10 years and investigate the risk factors associated with failure of initial percutaneous therapy. METHODS:A retrospective study of records of 63 PLA patients presenting between 1998 and 2008 to Australian tertiary referral centre, were rev...

journal_title：World journal of gastroenterology

authors： Pang TC,Fung T,Samra J,Hugh TJ,Smith RC

更新日期：2011-03-28 00:00:00

abstract：:Helicobacter pylori (H. pylori) infection has been clearly linked to peptic ulcer disease and some gastrointestinal malignancies. Increasing evidence demonstrates possible associations to disease states in other organ systems, known as the extraintestinal manifestations of H. pylori. Different conditions associated wi...

journal_title：World journal of gastroenterology

authors： Wong F,Rayner-Hartley E,Byrne MF

更新日期：2014-09-14 00:00:00

abstract：:The incidence of obesity has dramatically increased in recent years. Consequently, obesity and associated disorders such as nonalcoholic fatty liver disease constitute a serious problem. Therefore, the contribution of adipose tissue to metabolic homeostasis has become a focus of interest. In this review, we discuss th...

journal_title：World journal of gastroenterology

authors： Tarantino G,Caputi A

更新日期：2011-09-07 00:00:00

abstract：AIM:To investigate the effects of restraint stress on chronic colitis in interleukin (IL)-10 deficient (IL-10(-/-)) mice. METHODS:The first experiment compared the effect of restraint stress on the development of intestinal inflammation in wild-type and IL-10(-/-) mice. Both wild-type and IL-10(-/-) mice were physical...

journal_title：World journal of gastroenterology

authors： Koh SJ,Kim JW,Kim BG,Lee KL,Kim JS

更新日期：2015-07-28 00:00:00

abstract：AIM:To investigate and compare the hepatogenic transdifferentiation of adipose tissue-derived stem cells (ADSC) and bone marrow-derived mesenchymal stem cells (BMSC) in vitro. Transdifferentiation of BMSC into hepatic cells in vivo has been described. Adipose tissue represents an accessible source of ADSC, with similar...

journal_title：World journal of gastroenterology

authors： Taléns-Visconti R,Bonora A,Jover R,Mirabet V,Carbonell F,Castell JV,Gómez-Lechón MJ

更新日期：2006-09-28 00:00:00

abstract：:Angiosarcoma is a rare primary malignant neoplasm of the liver with a poor prognosis. Here, we report a case of a patient with a ruptured hepatic angiosarcoma which was treated by emergency catheter-directed embolization, followed by left-sided hemihepatectomy. ...

journal_title：World journal of gastroenterology

authors： Leowardi C,Hormann Y,Hinz U,Wente MN,Hallscheidt P,Flechtenmacher C,Buchler MW,Friess H,Schwarzbach MH

更新日期：2006-02-07 00:00:00

abstract：:This issue presents different new techniques aiming to increase our understanding of the gastrointestinal system and to improve treatment. The technologies cover selected methods to evoke and assess gut pain, new methods for imaging and physiological measurements, histochemistry, pharmacological modelling etc. There i...

journal_title：World journal of gastroenterology

authors： Drewes AM,Gregersen H

更新日期：2009-01-14 00:00:00

abstract：AIM:To investigate the effect of synbiotics, i.e. probiotics and prebiotics mixture, on the gut microbial ecology and digestive enzyme activities in rats. METHODS:Forty-eight SD rats weighing about 280 g were used in this study. Rats were divided into three groups according to the contents of probiotics and prebiotics...

journal_title：World journal of gastroenterology

authors： Yang SC,Chen JY,Shang HF,Cheng TY,Tsou SC,Chen JR

更新日期：2005-12-21 00:00:00

abstract：AIM:To identify a molecular marker for gastric cancer, and to investigate the relationship between the polymorphism of pepsinogen C (PGC) gene and the genetic predisposition to gastric cancer. METHODS:A total of 289 cases were involved in this study. 115 cases came from Shenyang area, a low risk area of gastric cancer...

journal_title：World journal of gastroenterology

authors： Liu HJ,Guo XL,Dong M,Wang L,Yuan Y

更新日期：2003-01-01 00:00:00

abstract：:Novel molecular targets are being discovered as we learn more about the aberrant processes underlying various cancers. Efforts to translate this knowledge are starting to impact on the care of patients with gastrointestinal cancers. The epidermal growth factor receptor (EGFR) pathway and angiogenesis have been targete...

journal_title：World journal of gastroenterology

authors： Ma WW,Hidalgo M

更新日期：2007-11-28 00:00:00

abstract：AIM:To assess the clinical presentation and genotypes of delta hepatitis in local population. METHODS:In this prospective study, 39 consecutive patients who were positive for HBsAg and hepatitis D virus (HDV) antibody were included. The patients were divided in two groups on the basis of presence or absence of HDV RNA...

journal_title：World journal of gastroenterology

authors： Moatter T,Abbas Z,Shabir S,Jafri W

更新日期：2007-05-14 00:00:00

abstract：AIM:To look for the evidence of human papilloma virus (HPV) infection in esophageal squamous cell carcinomas (ESCC) and to investigate the potential role and epidemiology of HPV infection in the pathogenesis of esophageal carcinomas in Henan emigrants. METHODS:Papilloma virus(PV) and HPV were determined by Ultrasensiv...

journal_title：World journal of gastroenterology

authors： Yao PF,Li GC,Li J,Xia HS,Yang XL,Huang HY,Fu YG,Wang RQ,Wang XY,Sha JW

更新日期：2006-03-07 00:00:00

abstract：AIM:To elucidate the expression of the apoptosis-associated molecules in human primary hepatocellular carcinoma (HCC) cells, and prepare the monoclonal antibodies (mAb) against the apoptosis-associated antigens of HCC cells. METHODS:Human HCC cell line HCC-9204 cells were induced apoptosis with 60 mL x L(-1) ethanol f...

journal_title：World journal of gastroenterology

authors： Yang LJ,Wang WL

更新日期：2002-10-01 00:00:00