Effect of synbiotics on intestinal microflora and digestive enzyme activities in rats.

abstract：:Over the last 15 years, there have been major advances in the multimodal treatment of gastric cancer, in large part due to several phase III studies showing the treatment benefits of neoadjuvant and adjuvant chemotherapy and chemoradiation protocols. The objective of this editorial is to review the current high-level ...

journal_title：World journal of gastroenterology

authors： Choi AH,Kim J,Chao J

更新日期：2015-06-28 00:00:00

abstract：AIM:To investigate the predictive factors of self-expandable metallic stent patency after stent placement in patients with inoperable malignant gastroduodenal obstruction. METHODS:A total of 116 patients underwent stent placements for inoperable malignant gastroduodenal obstruction at a tertiary academic center. Clini...

journal_title：World journal of gastroenterology

authors： Kim SH,Chun HJ,Yoo IK,Lee JM,Nam SJ,Choi HS,Kim ES,Keum B,Seo YS,Jeen YT,Lee HS,Um SH,Kim CD

更新日期：2015-08-14 00:00:00

abstract：:Elastography-based liver stiffness measurement (LSM) is a non-invasive tool for estimating liver fibrosis but also provides an estimate for the severity of portal hypertension in patients with advanced chronic liver disease (ACLD). The presence of varices and especially of varices needing treatment (VNT) indicates dis...

journal_title：World journal of gastroenterology

authors： Paternostro R,Reiberger T,Bucsics T

更新日期：2019-01-21 00:00:00

abstract：AIM:To examined the bile acid receptor TGR5 expression in squamous mucosa, Barrett's mucosa, dysplasia and esophageal adenocarcinoma (EA). METHODS:Slides were stained with TGR5 antibody. The staining intensity was scored as 1+, 2+ and 3+. The extent of staining (percentage of cells staining) was scored as follows: 1+,...

journal_title：World journal of gastroenterology

authors： Marketkar S,Li D,Yang D,Cao W

更新日期：2017-02-28 00:00:00

abstract：AIM:To study the effects of palmatine, a known inhibitor on delayed rectifier potassium current and L-type calcium current (I(Ca,L)) in guinea pig ventricular myocytes, on the potassium and calcium currents in isolated rat hepatocytes. METHODS:Tight-seal whole-cell patch-clamp techniques were performed to investigate ...

journal_title：World journal of gastroenterology

authors： Wang F,Zhou HY,Cheng L,Zhao G,Zhou J,Fu LY,Yao WX

更新日期：2003-02-01 00:00:00

abstract：:Hilar tumors have proven to be a challenge to treat and manage because of their poor sensitivity to conventional therapies and our inability to prevent or to detect early tumor formation. Endoscopic stent drainage has been proposed as an alternative to biliary-enteric bypass surgery and percutaneous drainage to pallia...

journal_title：World journal of gastroenterology

authors： De Palma GD,Masone S,Rega M,Simeoli I,Salvatori F,Siciliano S,Maione F,Girardi V,Celiento M,Persico G

更新日期：2007-08-14 00:00:00

abstract：:The severity of fecal incontinence widely varies and can have dramatic devastating impacts on a person's life. Fecal incontinence is common, though it is often under-reported by patients. In addition to standard treatment options, new treatments have been developed during the past decade to attempt to effectively trea...

journal_title：World journal of gastroenterology

authors： Van Koughnett JA,Wexner SD

更新日期：2013-12-28 00:00:00

abstract：AIM:To identify a molecular marker for gastric cancer, and to investigate the relationship between the polymorphism of pepsinogen C (PGC) gene and the genetic predisposition to gastric cancer. METHODS:A total of 289 cases were involved in this study. 115 cases came from Shenyang area, a low risk area of gastric cancer...

journal_title：World journal of gastroenterology

authors： Liu HJ,Guo XL,Dong M,Wang L,Yuan Y

更新日期：2003-01-01 00:00:00

abstract：AIM:To study the effect of sulfated cholecystokinin-octapeptide (CCK-8) on systemic hypotension, gene and protein expression of TNF-alpha in the spleen of lipopolysaccharide (LPS)-induced endotoxic shock (ES) rats, and further investigate the signal transduction mechanism of p38 mitogen-activated protein kinase (MAPK)....

journal_title：World journal of gastroenterology

authors： Meng AH,Ling YL,Zhang XP,Zhao XY,Zhang JL

更新日期：2002-02-01 00:00:00

abstract：:AIM:To study the relationship between insulin A chain regions and insulin biological activities, we designed a series of insulin analogues with changes at A21, A12-18 of C terminal helical region and A8-10 located in the region of A6-A11 intra-chain disulphide bond.METHODS:Insulin A-chain analogues were prepared by st...

journal_title：World journal of gastroenterology

authors： Yang SZ,Huang YD,Jie XF,Feng YM,Niu JY

更新日期：2000-06-01 00:00:00

abstract：:Because of the low prevalence of non-ampullary duodenal epithelial tumors (NADETs), standardized clinical management of sporadic superficial NADETs, including diagnosis, treatment, and follow-up, has not yet been established. Retrospective studies have revealed certain endoscopic findings suggestive of malignancy. Duo...

journal_title：World journal of gastroenterology

authors： Kakushima N,Kanemoto H,Tanaka M,Takizawa K,Ono H

更新日期：2014-09-21 00:00:00

abstract：AIM:Overexpression of tumor protein p53-induced nuclear protein 1 (TP53INP1) induces G1 cell cycle arrest and increases p53-mediated apoptosis. To clarify the clinical importance of TP53INP1, we analyzed TP53INP1 and p53 expression in gastric cancer. METHODS:TP53INP1 and p53 expression were examined using immunohistoc...

journal_title：World journal of gastroenterology

authors： Jiang PH,Motoo Y,Garcia S,Iovanna JL,Pébusque MJ,Sawabu N

更新日期：2006-02-07 00:00:00

abstract：:We report the case of a 21-year-old man who was noted to have pneumomediastinum during an admission for an acute flare of ulcerative colitis. At that time, he was on maintenance treatment with azathioprine at a dose of 1.25 mg/kg per day, and had not received supplementary steroids for 9 mo. He had never received anti...

journal_title：World journal of gastroenterology

authors： Lee JC,Bell DC,Guinness RM,Ahmad T

更新日期：2009-04-21 00:00:00

abstract：:The advances of laparoscopic surgery since the early 1990s have caused one of the largest technical revolutions in medicine since the detection of antibiotics (1922, Flemming), the discovery of DNA structure (1953, Watson and Crick), and solid organ transplantation (1954, Murray). Perseverance through a rocky start an...

journal_title：World journal of gastroenterology

authors： Kaiser AM

更新日期：2014-11-07 00:00:00

abstract：:Castleman's disease (CD) is a rare lymphoproliferative disorder of unknown etiology. Clinically, it occurs as a localized (unicentric) disease or as a systemic (multicentric) disease. Unicentric Castleman's disease (UCD) presents as a solitary mass and primarily affects the mediastinal, retroperitoneal, and cervical l...

journal_title：World journal of gastroenterology

authors： Lee HJ,Jeon HJ,Park SG,Park CY

更新日期：2015-02-07 00:00:00

abstract：AIM:To study the effect of IGF-1/IGF-1R and gastrin/CCK-BR on carcinogenesis and development of human gastric carcinoma and to explore its mechanism and provide a credible theoretical foundation for early diagnosis and molecular therapy of gastric carcinoma. METHODS:mRNA expression levels of IGF-1/IGF-1R and gastrin/C...

journal_title：World journal of gastroenterology

authors： Zhao MD,Hu XM,Sun DJ,Zhang Q,Zhang YH,Meng W

更新日期：2005-06-07 00:00:00

abstract：:Helicobacter pylori (H. pylori) colonizes the stomach of humans and causes chronic infection. The majority of bacteria live in the mucus layer overlying the gastric epithelial cells and only a small proportion of bacteria are found interacting with the epithelial cells. The bacteria living in the gastric mucus may act...

journal_title：World journal of gastroenterology

authors： Dunne C,Dolan B,Clyne M

更新日期：2014-05-21 00:00:00

abstract：:We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation. Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during ...

journal_title：World journal of gastroenterology

authors： Lin CH,Yu JC,Chen TW,Chan DC,Chen CJ,Hsieh CB

更新日期：2005-09-14 00:00:00

abstract：:Colorectal adenocarcinoma (CRC) is the third most common type of cancer and the fourth most frequent cause of death due to cancer worldwide. Given the natural history of CRC, early diagnosis appears to be the most appropriate tool to reduce disease-related mortality. A field of recent interest is clinical proteomics, ...

journal_title：World journal of gastroenterology

authors： de Noo ME,Tollenaar RA,Deelder AM,Bouwman LH

更新日期：2006-11-07 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) encompasses a range of liver histology severity and outcomes in the absence of chronic alcohol use. The mildest form is simple steatosis in which triglycerides accumulate within hepatocytes. A more advanced form of NAFLD, non-alcoholic steatohepatitis, includes inflammation and...

journal_title：World journal of gastroenterology

authors： Pacifico L,Nobili V,Anania C,Verdecchia P,Chiesa C

更新日期：2011-07-14 00:00:00

abstract：AIM:To explore the effects of peptide S-8300 from shark liver (S-8300) on liver function as well as in regulating immune functions in experimental injury models. METHODS:Mice were administered with different doses of S-8300 for four consecutive days, followed by mice injected with tetrachloromethane (CCl(4)) on d 3. T...

journal_title：World journal of gastroenterology

authors： Huang FJ,Lv ZB,Li Q,Wei LJ,Zhang L,Wu WT

更新日期：2005-03-28 00:00:00

abstract：:Hepatitis B virus (HBV) and hepatitis C virus (HCV) share common mode of transmission and both are able to induce a chronic infection. Dual HBV/HCV chronic coinfection is a fairly frequent occurrence, especially in high endemic areas and among individuals at high risk of parenterally transmitted infections. The intrac...

journal_title：World journal of gastroenterology

authors： Caccamo G,Saffioti F,Raimondo G

更新日期：2014-10-28 00:00:00

abstract：:Oncological treatment is currently directed toward a tailored therapy concept. Squamous cell carcinoma of the anal canal could be considered a suitable platform to test new therapeutic strategies to minimize treatment morbidity. Standard of care for patients with anal canal cancer consists of a combination of radiothe...

journal_title：World journal of gastroenterology

authors： De Nardi P,Carvello M,Staudacher C

更新日期：2012-11-28 00:00:00

abstract：:Since the development of uncovered self-expanding metal stents (SEMS) in the 1990s, endoscopic stents have evolved dramatically. Application of new materials and new designs has expanded the indications for enteral SEMS. At present, enteral stents are considered the first-line modality for palliative care, and numerou...

journal_title：World journal of gastroenterology

authors： Kim EJ,Kim YJ

更新日期：2016-01-14 00:00:00

abstract：AIM:To investigate the changing patterns of glycogen and enzyme histochemical activities in rat liver graft under a different warm ischemia time (WIT) and to predict the tolerant time limitation of the liver graft to warm ischemia injury. METHODS:The rats were randomized into five groups, WIT was 0, 15, 30, 45, 60 min...

journal_title：World journal of gastroenterology

authors： He XS,Ma Y,Wu LW,Wu JL,Hu RD,Chen GH,Huang JF

更新日期：2005-05-07 00:00:00

abstract：:In the last decade trans-arterial radioembolization has given promising results in the treatment of patients with intermediate or advanced stage hepatocellular carcinoma (HCC), both in terms of disease control and tolerability profile. This technique consists of the selective intra-arterial administration of microsphe...

journal_title：World journal of gastroenterology

authors： Sacco R,Mismas V,Marceglia S,Romano A,Giacomelli L,Bertini M,Federici G,Metrangolo S,Parisi G,Tumino E,Bresci G,Corti A,Tredici M,Piccinno M,Giorgi L,Bartolozzi C,Bargellini I

更新日期：2015-06-07 00:00:00

abstract：AIM:To study the efficacy and factors associated with a sustained virological response (SVR) in chronic hepatitis C (CHC) relapsing patients. METHODS:Out of 1228 CHC patients treated with pegylated interferon (PEG-IFN) and ribavirin (RBV), 165 (13%) had a relapse. Among these, 62 patients were retreated with PEG-IFN-α...

journal_title：World journal of gastroenterology

authors： Stern C,Martinot-Peignoux M,Ripault MP,Boyer N,Castelnau C,Valla D,Marcellin P

更新日期：2012-06-21 00:00:00

abstract：:Peritoneal carcinomatosis appears to be the most common pattern of metastasis or recurrence and is associated with poor prognosis in gastric cancer patients. Many efforts have been made to improve the survival in patients with peritoneal metastasis. Hyperthermic intraperitoneal chemotherapy remains a widely accepted s...

journal_title：World journal of gastroenterology

authors： Wei J,Wu ND,Liu BR

更新日期：2016-09-07 00:00:00

abstract：:We review the case of a 74-year-old patient with advanced colon cancer who suffered recurrent bouts of hypoglycemia. A state of inappropriate, non-suppressed hyperinsulinism in the presence of severe hypoglycemia was diagnosed. We finally discuss the known mechanisms behind fasting hypoglycemia in patients with advanc...

journal_title：World journal of gastroenterology

authors： Díaz R,Aparicio J,Mendizábal A,Faus M,Fleitas T,Aparisi F,Martín M

更新日期：2008-03-28 00:00:00

abstract：AIM:To study the anti-hepatofibrosis mechanism of Bie Jia Jian oral liquid (BOL). METHODS:The model was induced by subcutaneous injection of CCl(4). BOL was administered and the change of serum hyaluronic acid (HA) and laminin (LN) was observed and the degeneration of liver cells and the degree of fibre hyperplasia an...

journal_title：World journal of gastroenterology

authors： Yao L,Yao ZM,Yu T

更新日期：2001-12-01 00:00:00